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이희정,정희선,주나미,Lee, Heejeong,Jeong, Hee Sun,Joo, Nami 한국식품조리과학회 2015 한국식품조리과학회지 Vol.31 No.2
본 연구에서는 아가리쿠스 버섯 가루를 첨가한 쿠키 제조 조건의 최적화를 위해 아가리쿠스 버섯 가루와 버터의 양을 독립변수로 하였고, Design Expert 8(State-easy Co.)을 사용하여 실험을 계획하고 최적화하였다. 아가리쿠스 버섯 가루와 버터의 최대 및 최소범위는 예비실험을 거쳐 아가리쿠스 버섯 가루는 1~5 g, 버터는 40~70 g으로 하여 쿠키를 제조하여 이화학적, 관능적 특성 검사를 실시하였다. 1. 쿠키의 수분함량은 유의적으로 아가리쿠스 버섯과 버터의 첨가량이 증가할수록 수분함량이 증가하였고(p<0.001), 독립변수가 서로 상호작용하는 2FI model이 선정되었으며, 이는 버섯의 식이섬유소의 수분 보유 성질에 의해 수분 보유력이 증가한 것으로 판단된다. 반죽의 수분함량은 유의적인 차이는 아니지만 아가리쿠스 버섯이 증가할수록 감소하고 버터가 증가할수록 증가하는 경향을 보였다. 2. pH와 당도는 아가리쿠스 버섯과 버터의 첨가량이 증가할수록 감소하였으나 유의적인 차이는 아니었다. 색도에서 명도는 아가리쿠스 버섯 가루 1 g과 버터 70 g에서 가장 높았고, 0.1%수준에서 유의적인 차이가 있었다. 적색도는 아가리쿠스 버섯 첨가량이 증가할수록 급격하게 증가하였으며 0.1%수준에서 유의적인 차이를 보였고 이는 버섯 특유의 색상이 영향을 준 것으로 판단된다. 황색도에서는 유의적인 차이는 없었다. 3. 퍼짐성은 아가리쿠스 버섯 가루와 버터의 양이 증가할수록 증가하였고 5% 수준에서 유의한 것으로 나타났으며, 경도는 버터의 첨가량이 증가할수록 급격하게 감소하는 것으로 나타났으나 유의적인 차이는 없었다. 4. 관능적 특성에서 색, 향미, 조직감, 전체적인 기호도 항목은 5% 수준에서 유의한 것으로 나타났으며, 아가리쿠스 버섯 가루와 버터의 양이 많아질수록 기호도는 일정수준까지 증가하다가 급격히 감소한 것으로 나타났다. 관능의 모든 항목에서 아가리쿠스 버섯 가루 3.5 g 버터 55 g에서 기호도가 가장 높은 것으로 나타났다. 5. 이상의 실험 결과를 바탕으로 아가리쿠스 버섯 쿠키의 유의적인 관능항목의 수치 최적화와 모형적 최적화를 통해 관능적 최적 배합비율은 아가리쿠스 버섯 가루 3.63g과 버터 55.37 g으로 산출되었다. 본 연구를 통해 아가리쿠스 버섯 쿠키의 영양, 기능, 품질, 기호도 측면에서 상품화를 위한 충분한 가능성이 있다고 판단되며, 아가리쿠스 버섯을 이용한 식품개발 가능성을 확인할 수 있었다. The purpose of this study was to determine the optimal mixing ratio of Agaricus blazei Murill powder and butter in the preparation of cookies. The experimental design utilized herein was based on central composite design for response surface methodology, which included 10 experimental points, including 2 replicates for Agaricus blazei Murill and butter. The physical, mechanical, and sensory properties of the test were measured, and these values were applied to the mathematical models. A canonical form and perturbation plot showed the influence of each ingredient on the final mixed product. The spread ratio increased significantly with an increase in Agaricus blazei Murill powder and butter (p<0.05). The response surface methodology was applied to evaluate the effect of Agaricus blazei Murill powder and butter on cookie moisture and color (L, a) (p<0.001). Sensory evaluation showed significant values for color (p<0.05), flavor (p<0.05), texture (p<0.05) and overall quality (p<0.01) in the predicted model. The optimum formulation by numerical and graphical methods was calculated as follows: Agaricus blazei Murill powder 3.63 g, butter 55.37 g.
사기질모세포종의 세침흡인 세포학적 소견 - 1예 보고-
이희정,김병기,강창석,정은선,Lee, Hee-Jeong,Kim, Byung-Kee,Kang, Chang-Suk,Jung, Eun-Sun 대한세포병리학회 2002 대한세포병리학회지 Vol.13 No.2
Utilization of fine needle aspiration cytology (FNAC) in the diagnosis of odontogenic tumors seems to have little attention. Ameloblastoma is the most common epithelial odontogenic tumor. However, the cytologic findings of ameloblastoma are described recently. We report a case of ameloblastoma diagnosed by FNAC. The aspirated blood-tinged mucoid fluid from maxillary mass showed a few clusters of tumor cells with distinct two-cell population: basaloid cells with palisading arrangement and squamous cells with more abundant and eosinophilic cytoplasm. Nuclear atypism, pleomorphism or mitosis were absent. A few keratinized bodies in the tumor cell clusters and the third component, stellate cells were also characteristic.
Film screen system과 DR system하의 상부위장관 조영술 진단 결과의 비교 분석
이희정,손순룡,강성호,장용철,류명선,Lee Hee Jeong,Son Soon Yong,Kang Sung Ho,Jang Vong Cheol,Ryu Myeong Sun 대한방사선사협회 2002 대한방사선사협회지 Vol.28 No.1
Purpose : The aim of this study is to rise interest in system control for digital image of high quality by investigating diagnostic value of Digital radiographic system in upper gastrointestinal study Materials and Method : Upper gastrointestinal study wa
한국 소아 기관지 천식 환아에서 연령에 따른 Theophylline 의 대사 변화에 관한 연구
이희정(Hee Jeong Lee),조혜영(Hye Young Cho),윤운기(Un Ki Youn),오지섭(Ji Sub Oh),류환선(Hwan Seon Ryu),손기호(Kie Ho Sohn),(Charles D . Sands) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 1995 소아알레르기 및 호흡기학회지 Vol.5 No.1
N/A Theophylline is widely used in Korean pediatric patients in the treatment of asthma. To achieve adequate bronchodilation and avoid side effects , it is generally accepted that the serum theophylline concentration should be maintained between 10 and 20mcg/ml . Concentrations greater than 20mcg/ml are associated with an increased incidence of toxicity . Clinical effectiveness and toxicity are clearly related to understand factors which might altel theophylline pharmacokinetics . Age has been reported as a factor which might alter theophylline clearance. Thus we studied 287 asthmatic children who were admitted to our hospital and received intravenous aminophylline and oral theophylline. The average total clearance of theophylline was 30.00ml/kg/h in the infants under 6 months old and 53.14ml/kg/h in the infants between the age of 6 and 12 months . The average total clearance of theophylline was significantly increased in infants above 6 months old(p<0.001) . The average total clearance of theophylline of the children aged between 1 to 12 years was 65.77ml/kg/h and no significant difference according to age was noticed in this group . These suggest that age may be a factor which affects clearance of theophylline under 12 months old .
이희정 ( Hee Jung Lee ),정현용 ( Hyun Yong Jeong ),박남환 ( Nam Hwan Park ),홍순창 ( Sun Chang Hong ),남관우 ( Gwan Woo Nam ),문희석 ( Hee Seok Moon ),이엄석 ( Eaum Seok Lee ),김석현 ( Seok Hyun Kim ),성재규 ( Jae Kyu Sung ),이병 대한소화기학회 2011 대한소화기학회지 Vol.57 No.4
Background/Aims: Recently colonoscopy and screening programs have led to the detection and removal of increasing numbers of early colorectal cancer (ECC), which can reduce its related mortality. We analysed the clinical, endoscopic, and histologic findings, as well as the follow-up data, to evaluate the effectiveness and the long-term results of endoscopic mucosal resection (EMR) for ECC. Methods: We analysed, retrospectively, 94 lesions in 92 patients who underwent EMR for ECC from January 2002 to June 2009. Results: The overage age of patients was 60 years old. The mean follow-up period was 22.1 months (6-80). En bloc resection rate was 64.9%. Submucosal invasion was found in 30 cases (31.9%). De novo cancer rate was 26.6% which had higher submucosal invasion rate (60%, p=0.003). The complete resection rate was 87.2%, and there was no recurrence of cancer during follow-up (p=0.000). Twelve incomplete resection cases had received further surgical treatments. No procedure-related mortality was found and no recurrent malignancy was found except 1 case. Conclusions: This study shows that EMR is an effective and safe treatment for ECC. En bloc resection provides precise histologic information and prevention of tumor recurrence. (Korean J Gastroenterol 2011;57:230-236)
증례 : 순환기 ; 심정지 이후에 장시간 시행된 흉부압박에 의해 발생한 우심실 파열 1예
이희정 ( Hee Jeong Lee ),권성순 ( Seong Soon Kwon ),강혜란 ( Hye Ran Kang ),방덕원 ( Duk Won Bang ),박병원 ( Byoung Won Park ),이민호 ( Min Ho Lee ),장원호 ( Won Ho Chang ) 대한내과학회 2015 대한내과학회지 Vol.88 No.4
원인이 명확하지 않은 46세 급성 심장정지 환자에서 2시간 이상의 흉부압박을 시행 후 자발 순환 회복되었으나 설명되지 않는 지속적 저혈압을 보여 반복적인 심초음파를 시행하였고, 심낭압전 및 혈심낭이 확인되어 진단적 개흉술로 우심실벽 파열을 진단한 환자를 경험하여 보고하는 바이다. A 46-year-old male arrived at the emergency department with acute dyspnea. On the way to the hospital, heart massage was performed in the ambulance due to asystole on electrocardiography. After 2 hr of resuscitation, sinus rhythm was restored. Extracorporeal life support and an intra-aortic balloon pump were applied due to cardiogenic shock, but the patient showed sustained hypotension. Echocardiography showed moderate pericardial effusion with physiological evidence of cardiac tamponade; emergency pericardiocentesis was performed, which produced bloody pericardial fluid. An explorative sternotomy revealed a massive hematoma in the mediastinum and right ventricular (RV) free wall rupture. After primary repair, echocardiography showed improved left ventricular systolic function and the patient was stable clinically. This case presents RV free wall rupture as an unusual complication of prolonged heart massage. Heart rupture should be considered in hemodynamically unstable patients after prolonged heart massage.