골판지 고지의 물리화학적 처리에 의한 강도향상(제3보) - 수초지의 물리적 특성변화 -

이종훈,서영범,전양,이학래,신종호,Lee, Jong-Hoon,Seo, Yung B.,Jeon, Yang,Lee, Hak-Lae,Shin, Jong-Ho 한국펄프종이공학회 2000 펄프.종이기술 Vol.32 No.2

This study is a continuation of the previous experimental analysis and is mostly focused on handsheet strength properties. Four completely different fibers, which were Hw-BKP, SW-BKP, White ledger, and OCC, were selected to investigate the effect of mechanical pre-treatment by Hobart mixer on handsheet strehgth properties. After equal time mechanical pre-treatment, the fibers were refined with laboratory valley beater for 10, 20 and 30 minutes, and handsheets were prepared from the fibers for physical strength comparison. Handsheets from SW-BKP and OCC showed 5-30% increase of breaking length, burst index, tear index, and compression index while handsheets from HW-BKP and White ledger no increase except tear index. In Hobart mixer pre-treatment, HW-BKP and White ledger fibers were easily attached to the wall of the mixer bowl and mechanical action was not effectively applied. The fiber length of Hw-BKP and White ledger were 0.837 mm and 1.591 mm, respectively, while SW-BKP and OCC were 2.744 mm and 2.033 mm, respectively, in weight weighted length. The effective mechanical pre-treatment seems to be related to the fiber length. Tear indexes of the pre-treated furnish were much higher than no pre-treatment at the same breaking length level.

골판지 고지의 물리화학적 처리에 의한 강도향상(제2보)

이종훈,서영범,전양,이학래,신종호,Lee, Jong-Hoon,Seo, Yung B.,Jeon, Yang,Lee, Hak-Lae,Shin, Jong-Ho 한국펄프종이공학회 2000 펄프.종이기술 Vol.32 No.2

In the previous experiment, it was found that OCC pre-treatment with Hobart mixer at 20-25% consistency for 3 hrs or more followed by the application of the equal refining time, caused the increase of tensile strength, burst strength, compressive strength and tear resistance, compared to the no pre-treated. Four completely different fibers, which were Hw-BKP, Sw-BKP, White ledger, and OCC were selected for this experiment to investigate the effect of mechanical pre-treatment process on different fibers. From the experiment, it was found that the mechanical pre-treatment did not decrease fiber length at all, but decreased freeness, com-pared to the no pre-treated, when the same refining time was applied. WRVs of the pre-treated fibers were higher than the no pre-treated at the same freeness level. It was speculated that the mechanical pre-treatment induced only hydrophilic nature of fibers without damaging fiber length by delaminating fiber walls. The fiber surface area and the physical strength differences of handsheets will be discussed in the next publication.

Ilizarov 시술 후 추적검사에 있어 초음파검사의 유용성 : 단순촬영과의 비교

이종훈,지성우,이호원,이성문,김정식,김홍,송광순,조길호,우성구,Lee, Jong Hoon,Jee, Sung Woo,Lee, Ho Won,Lee, Sung Moon,Kim, Jung Sik,Kim, Hong,Song, Kwang Soon,Cho, Kil Ho,Woo, Sung Ku 대한영상의학회 1998 대한영상의학회지 Vol.38 No.6

Purpose : To compare the usefulness of ultrasonography in follow up evaluation after the Ilizarov procedurewith that of plain radiography. Materials and Methods : We analyzed ultrasound findings in twelve patients who hadundergone the Ilizarov procedure, and retrospectively compared the results with the findings of plain radiography.The procedure was performed due to post-traumatic limb deformity or non-union(nine of twelve patients), congenitalpseudoarthrosis(one case), sequelae of poliomyelitis(one case), and short stature(one case). The patients' meanage was 29 years ; eleven of twelve were male. Ten of twelve procedures were performed on the tibia and two on thefemur. After 7-10 days, distraction was initiated at a rate of 0.25mm four times a day. Ultrasonography wasperformed with a 5-10 MHz linear or convex transducer ; new bone formation was defined as dotted or linearechogenic foci within a hypoechoic distraction gap. Initial ultrasonographic examination was performed 2-4 weeksafter distraction, and the results were compared with those of plain radiography. Color Doppler imaging wasperformed in three cases. Results : On ultrasonograms, new bone formation was initially detected 18-29(mean, 23)days after distraction, and on plain radiographs, 37-58(mean, 45) days after this procedure ; ultrasonography thusdetected new bone formation at least three weeks earlier than did plain radiography. Complication after theIlizarov procedure were four cysts at the distraction site, and one pin site infection, as seen on ultrasonograms.None of these four cysts, the size of which was 12-22mm(mean, 17mm), was visible on plain radiographs. In one casein which a cyst was present, ultrasound-guided aspiration was performed. Color Doppler examination was performedin three of twelve patients, and in all three, periosteal vascularity at the edge of the distracted gap was seento be preserved. Conclusion : After the Ilizarov bone lengthening procedure, ultrasound appears to be useful forfollow-up examination. New bone formation, as well as complications, can be detected earlier ; it can indicatewhether ultrasound-guided interventional procedure is required, and if combined with color Doppler study, is ableto detect the periosteal blood supply. Further evaluation of the clinical significance of preserved periostealblood supply seems however, to be needed.

부안정수장 송수펌프의 운영방안에 관한 연구

이종훈,이동원,윤영수,이정우,Lee, Jong-Hoon,Lee, Dong-Won,Yoon, Young-Soo,Lee, Jung-Woo 한국유체기계학회 2004 한국유체기계학회 논문집 Vol.19 No.4

랫드에서 hyaluronic acid에 의한 유착 방지 효과에 관한 연구

이종훈,이주명,윤영민,강태영,우호춘,강윤호,김남중,김희석,이경갑,정종태,Lee, Jong hoon,Lee, Joo Myoung,Yun, Young min,Kang, Tae young,Woo, Ho choon,Kang, Yoon ho,Kim, Nam joong,Kim, Hee seok,Lee, Kyoung kap,Cheong, Jongtae 대한수의학회 2004 大韓獸醫學會誌 Vol.44 No.4

This study was conducted to investigate the effect of hyaluronic acid (HA) on prevention of abdominal adhesions depending on various concentrations thereof by inducing an abrasion experimentally in the cecum of rats. Each group was consisted of 10 rats, and 40 rats were divided into 4 groups comprising the saline treatment group, HA 0.4% treated group, 0.6% treated group, and 0.8% treated group. And abrasion was caused in the cecum by using dry gauze and thereby, adhesion was induced. On 7 days after the operation, adhesions of each region were evaluated into the range of 0-4. Significant difference was found in the adhesion score between the control group and each experimental group (P<0.05). Also, HA 0.4% treatment group showed the lowest adhesion score (P<0.05). In the light of the above results, HA 0.4% solution was more effective on prevention of adhesion than HA 0.6% and 0.8% solution.

비인두암의 한의학적 진료 지침 개발을 위한 기초 연구

이종훈,강세영,유화승,Lee, Jong-hoon,Kang, Sei-young,Yoo, Hwa-seung 대한한방내과학회 2016 大韓韓方內科學會誌 Vol.37 No.3

Objectives: The purpose of this study is to present clinical practice guidelines for nasopharyngeal cancer (NPC).Methods: Data related to western and oriental medical treatment of NPC were collected using various search engines such as Google Scholar, KIOM OASIS, PUBMED, and the library of Woosuk University.Results: In recent studies, applying combined oriental and western medicine has been shown to improve survival, quality of life, and immune function and to decrease side effects with respect to NPC. However, there still is no objective and systematic clinical guideline for NPC, so we have proposed one. This study will be meaningful in establishing clinical practice guidelines of Korean medicine for NPC.Conclusion: Further studies related to Korean medicine are needed to develop more advanced clinical practice NPC guidelines.

흰 쥐의 감염된 전층피부 결손에서 Iodine의 드레싱 방법에 따른 창상치유 효과의 비교

이종훈,김요한,민경희,홍성희,이원미,채정돈,전진현,Lee, Jong-Hoon,Kim, Yo-Han,Min, Kyung-Hee,Hong, Sung-Hee,Lee, Won-Mi,Chae, Jeong-Don,Jun, Jin-Hyun 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.3

Purpose: Iodine has been used for the prevention or management of wound infection as a topical agent. Although iodine was widely used mainly by Betadine$^{(R)}$ and cadexomer iodine, there was no comparative study on the efficacies of dressing methods of iodine. And also it's wound healing effect was not yet clear. The purpose of this study is to compare antibacterial effects and wound healing effects associated with various dressing methods of iodine on infected full thickness skin defect in the mouse. Methods: One full thickness skin defects in the mice (n=60) were developed on the back and left open for twenty-four hours. Sixty mice were divided into four groups : group S (dressing with Betadine$^{(R)}$ soaking, n=15), group T (dressing with Betadine$^{(R)}$ topping, n=15), group I (dressing with Iodosorb$^{(R)}$, n=15), group G (control group, dressing with dry gauze, n=15). The size of the wound defects and the grades of wound healing were evaluated in 4, 7, 10 days, and antibacterial effect was evaluated with restricted zone in Mueller Hinton agar by disk diffusion method. Results: After the wound was left open for twenty-four hours, many Staphylococcus aureus were cultured. The wound defect size was decreased in order of Betadine$^{(R)}$ soaking, Iodosorb$^{(R)}$, Betadine$^{(R)}$ topping and gauze dressing group in all days, but difference among experimental groups was not statistically significant. The grade score of wound healing was increased in order of Betadine$^{(R)}$ soaking, Iodosorb$^{(R)}$, Betadine$^{(R)}$ topping and gauze dressing group, and the difference was statistically significant. Antibacterial effect for S. aureus was increased in order of Iodosorb$^{(R)}$, Betadine$^{(R)}$ soaking, Betadine$^{(R)}$ topping and gauze dressing group, and the difference was statistically significant. Conclusion: Selection of the effective dressing method of iodine for infected wounds remains a controversial decision. According to this study, Iodosorb$^{(R)}$ may be most effective method for antibacterial effect and Betadine$^{(R)}$ soaking may be most effective method for infected wound healing. However, further study is necessary to evaluate the clinical efficacy of dressing methods of iodine and to search for the mechanisms that explain their effects.

연구논문 - 수명 및 건전성평가 - : HK40 Reformer Tube 의 장시간 사용에 따른 미세조직과 기계적 특성 변화

이종훈,강수현,이재현,조경식,최승주 ( Jong Hoon Lee,Soo Hyeon Kang,Je Hyun Lee,Kyung Shik cho,Seung Joo Choe ) 대한금속재료학회 ( 구 대한금속학회 ) 1996 재료강도 심포지엄 Vol.- No.-

인진청간탕(茵蔯淸肝湯)이 HepG2 cell의 인터페론 신호전달계에 미치는 영향

이종훈,김영철,이장훈,우홍정,Yi, Jong-Hoon,Kim, Young-Chul,Lee, Jang-Hoon,Woo, Hong-Jung 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.1

Objectives/Methods : To analyze the effect of Injinchunggantang(IJCGT) to Interferon-${\alpha}/{\beta}$ signal transmission system in HepG2 cells, HepG2 Cell were treated with IJCGT. Also, revelation of MxA, 2'5'-OAS mRNA leaded by Interferon-${\alpha}/{\beta}$ and revelation and activation of Jak1, TYK1, and STAT 1, all main signal transmission factors, were analyzed. Results : The analysis resulted in the following 1. With interferon ${\alpha}/{\beta}$ there was no affect cell propagation of Hep G2 cells. With IJCGT alone, cell propagation of HepG2 was promoted, and cell propagation control function was recovered. 2. With interferon ${\alpha}/{\beta}$ cell death was unaffected. With IJCGT apoptosis of HepG2 cell was restrained, and the cell's reaction to interferon was unaffected. 3. With interferon ${\alpha}/{\beta}$ treatment mRNA revelation of MxA and 2'5'-OAS was induced. When HepG2 cells were injected with IJCGT without interferon ${\alpha}/{\beta}$ treatment, mRNA revelation of MxA and 2'5'-OAS increased in proportion to the treatment density. With pre-treatment of IJCGT, leaded with interferon ${\alpha}/{\beta}$, promoted revelation of MxA, 2'5' -OAS mRNA. 4. Though mRNA revelation of lakl, TYK1 and STAT1 was unaffected with IJCGT, activation of STAT1 was promoted with an increase of phosphorylation of STAT1 protein. With pre-treatment of IJCGT, Jak1, TYK2, STAT1 phosphorylation, leaded with interferon, strengthened. 5. TNF-a, IL-1b and LPS present, revelation of MxA and 2'5'-OAS mRNA leaded by interferon was restrained when HepG2 cells were treated with IJCGT, and the interferon signal transmission system restraint action leaded by inflammatory cytokines was moderated. Conclusion : These results support a role for IJGCT in promotion of anti-virus action through maintainance of the liver's sensibility toward interferon. A clinical study of an interferon treated patient treated also with IJGCT is needed to determine its efficacy.

정렬에 무관한 마이크로옵틱 마하젠더 간섭계형 필터

이종훈,김현덕,송재원,Lee, Jong-Hoon,Kim, Hyun-Deok,Song, Jae-Won 한국광학회 2006 한국광학회지 Vol.17 No.3

광섬유형 콜리메이터와 광 진행 경로의 수직 방향으로 삽입된 주기적으로 식각된 줄무늬(stripe) 평판에 의해 진행하는 빔의 일부에 광 경로차를 유도하는 마이크로 옵틱형 마하젠더 간섭형 필터를 제안하고 구현하였다. 제안된 마이크로 옵틱 필터는 주기적으로 식각된 줄무늬(stripe) 구조의 평판을 빔 경로에 삽입하여 측방향 정렬에 무관하게 특정 소멸비 값 이상의 특성을 구현할 수 있으며, 식각된 박막의 두께를 조정함으로써 원하는 대역폭 및 주기의 전달특성을 가지는 필터를 구현할 수 있다. 네거티브 포토레지스터인 SU-8을 기반으로 줄무늬(stripe) 구조의 주기적으로 식각된 평판을 제작하였으며 이를 이용하여 구현된 필터의 소멸비는 측방향 정렬에 무관하게 30 dB이상의 값을 가진다. 제작된 필터의 FSR(Free Spectral Range)은 장파장 대역에서 약 237 nm이고 그리고 삽입손실은 2 dB 미만의 값을 가진다. 통과대역에서의 PDL(Polarisation Dependent Loss)값은 0.15 dB 미만이다. A novel alignment-free micro-optic MZI filter has been demonstrated. The filter is composed of two fiber-pigtailed collimators and a beam-splittingplate with a periodically etched stripe pattern. We fabricated the plate through a standard lithographic formulation process by using a pyrex substrate glass with SU-8 resist coating on its one of the surfaces. The maximum insertion loss of the implemented filter was less than 2 dB over 1000 nm to 1600 nm and the extinction ratio was larger than 33 dB. The measured PDL within the 3-dB pass band of the filter was less than 0.15dB and the maximum extinction ratio variation was less than 2 dB even when the worst alignment error occured.