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이호원,강승훈,이영선 한국정밀공학회 2014 International Journal of Precision Engineering and Vol. No.
In this study, dynamic recrystallization during nonisothermal hot compression test was numerically simulated by finite elementanalysis using new grain aggregate model for dynamic recrystallization. This model was developed based on mean field approachby assuming grain aggregate as representative element. For each grain aggregate, changes of state variables were calculated usingthree sub-models for work hardening, nucleation, and nucleus growth. A conventional single parameter dislocation density model wasused to calculate change of dislocation density in grains. For modeling nucleation, constant nucleation rate and nucleation criteriondeveloped by Roberts and Ahlblom were used. It was assumed that the nucleation occurs when the dislocation density of certain grainreaches a critical nucleation criterion. Conventional rate theory was used to model nucleus growth. The developed dynamicrecrystallization model was validated by comparing with isothermal hot compression of pure copper. Then, the finite element analysiswas conducted to predict the local changes of microstructure and average grain size by using the grain aggregate model. Thepredicted results were compared with nonisothermal hot compression results. The simulation results were in reasonably goodagreement with experimentally obtained microstructures and the calculation time was much shorter than cellular automata-finiteelement method.
이호원,양형진,이재은,김영관,하윤경 한국물리학회 2015 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.66 No.1
Transparent electrodes and heteroleptic iridium complexes have attracted tremendous scientificinterest to organic light-emitting diodes (OLEDs) because they have an advantage in that transparentelectrodes can replace indium-tin-oxide (ITO) electrode that has structural defects or diffuseindium into the organic layer. Moreover, heteroleptic iridium complexes exhibit high luminescenceand quantum yield, as well as superior device performance. Therefore, we propose the use of flexiblewhite OLEDs with semitransparent Ni/Ag/Ni multi-metal layers and a new combination of iridiumcomplex as an orange phosphorescent emitter. We demonstrate that flexible white OLEDs withITO-free electrodes and new orange phosphorescent emitters have the potential of stable electricaland optical characteristics.
이호원,권지욱,좌동경,홍석교 제어로봇시스템학회 2009 제어로봇시스템학회 국내학술대회 논문집 Vol.2009 No.9
In this paper,we discuss about pose estimation of multiple mobile robots system using by machine vision system.We improve target recognition and pose estimation algorithm that utilize two-dimensional marker which was developed before. First,we set upthree-dimensional marker to each mobile robots. Also, we estimate relative location and pose by getting calibrated image from camera.Then we use position of point on marker and minimizes quantity of processing data differently from past researches. Finally, this paper proposes algorithm thatcan apply to mobile robot by simplifying camera calibration and pose estimation
Clinicopathologic Implication of Ezrin Expression in Non-small Cell Lung Cancer
이호원,오미혜,김의한 대한병리학회 2012 Journal of Pathology and Translational Medicine Vol.46 No.5
Background: Ezrin, a member of the ezrin-radixin-moesin family, is implicated in tumor progression, metastatic dissemination, and adverse outcomes, in several cancer types. In this study, we explored the clinicopathological significance of ezrin expression in non-small cell lung carcinomas (NSCLCs). Methods: Immunohistochemical analysis of tissue microarray with 112 surgically resected NSCLC specimens, was performed to examine the ezrin expression. We also correlated ezrin expression with other clinicopathological features and prognosis. Results: The ezrin-positive group revealed significantly higher correlation with pleural invasion (p=0.016) and pathologic stage (p=0.050). Univariate survival analysis showed that ezrin-positive group had a significantly shorter cancer-specific survival than ezrin-negative group (p=0.016). Meanwhile, female (p=0.030), no pleural invasion (p=0.023), no lymphatic invasion (p=0.026), and early pathologic stage (p= 0.008) significantly correlated with longer survival. Multivariate survival analysis showed that variables such as ezrin positivity (p=0.032), female (p=0.035), and early pathologic stage (p=0.001) were independent prognostic factors for NSCLC. Conclusions: Ezrin might be a molecular marker to predict poor prognosis of NSCLC.
The Study About Physical Activity for Subjects With Prevention of Benign Prostate Hyperplasia
이호원,김신아,남지원,김미경,최보율,문홍상 대한배뇨장애요실금학회 2014 International Neurourology Journal Vol.18 No.3
Purpose: The number of benign prostatic hyperplasia (BPH) subjects has been increasing worldwide, and many studies have been conducted to determine the treatment that can delay drug therapy or surgery. Subsequently, most of these studies involved physical activity (PA) and associated factors. Therefore, we aimed to determine factors associated with BPH prevalence based on a review of past and present studies and to investigate the effect of a healthy lifestyle as a protective factor of BPH occurrence. Methods: We selected 582 subjects aged ≥40 years from an initial 779 subjects recruited from Gyeonggi, Yangpyeong, South Korea, during August 2009 to August 2011. Trained investigators surveyed International Prostate Symptom Score and demographic information, including PA and lifestyle questionnaire during face-to-face interviews; further, they performed digital rectal examination, rectal ultrasonography, and measured prostate-specific antigen levels. The statistical association between PA and BPH was analyzed by logistic regression analysis using multivariable regression models which use categorical variables by the Cochran-Mantel-Haenszel test and continuous variables by the general linear model. Results: Seven statistically significant variables for PA were selected. Regular exercise, frequency of exercise, sedentary time, nonsedentary time, leisure time PA (metabolic equivalent, hr/wk) were not statistically associated with prostate volume but sedentary time (hr/day) was the only factor that showed a significant association in the multivariable model, including a linear effect relationship. Subjects with lower levels of sedentary time (4.5–7.0 hr/day) had a significantly lower risk of BPH (odds ratio [OR], 0.93; 95% confidence interval [CI], 0.52–1.67) than those with a higher sedentary time (>7 hr/day) (OR, 1.72; 95% CI, 0.96–3.09) (P for trend=0.05). Conclusions: Our study showed that reducing sedentary time could have a protective effect and reduce the prevalence of BPH. Further prospective studies with a larger sample size are needed to assess the impact of reducing sedentary time on BPH risk.