林地利用에 따른 溪流水의 水質變化

具瀟瑛,鄭源玉,金弘洙,朴晋源,麻鎬燮 경상대학교 농과대학 부속연습림 2001 演習林硏究報告 Vol.- No.11

Table 2. Evaluation of stream water quality in three stands by Drinking water quality standard <원문참조> 임지이용에 따른 수질변화 및 오염정도를 구명하여 향후 비점오염원 관리를 위한 기초자료를 제공하고자 경남 진주시 정평리에 위치한 3개 임분(소나무, 밤나무Ⅰ, 반나무Ⅱ임분)에서 2000년 7월부터 9월까지 계류수의 수질변화를 분석하여 얻은 결과는 다음과 같다. 1. 세 임분의 계류수 pH는 소나무 임분(pH6.59)>밤나무 Ⅱ임분(ph 6.53)>밤나무 Ⅰ임분(pH 6.47)계류수 순으로 나타났다. 2. 전기전도도는 밤나무 Ⅰ임분>소나무 임분>밤나무 Ⅱ임분 계류수의 순으로 높게 나타났다. 3. 양이온은 세 임분의 계류수 모두 Ca^2+, Na^+, Mg^2+, K^+, NH_^+의 순으로 높게 나타났다. 4. 음이온은 소나무 임분과 밤나무 Ⅱ임분 계류수에서는 SO_4^2, Cl, NO_3의 순으로 높게 나타났고, 밤나무 Ⅰ임분 계류수에서는 NO_3, SO_4^2, Cl 의 순으로 높게 나타나 차이를 보였다. 5. 소나무, 밤나무 Ⅱ임분 계류수는 pH, NH_4+, NO_3, Cl, SO_4^2이 먹는 물 수질기준 범위내에 있었다. 그러나 밤나무 Ⅰ임분 계류수에서 5항목 중 NO_3는 먹는 물 수질기준을 넘어서는 범위에 있어 임지이용에 따른 하류수질의 오염이 우려되었다. 따라서 이러한 상류지역에서 오염원 차단을 위한 수질정화시설 등의 대책이 마련되어야 할 것으로 사료된다. This study was carried out to clarify the change characteristics of stream water quality by land-use of forest from July to September, 2000 in three stands(Pinus densiflora, Castanea crenata(Ⅰ), Castanea crenata(Ⅱ) stand) of Jeongpyeong-ri, Jinju-si, Gyeongnam. The mean pH of rainfall results in acid rain of 5.3. The pH of stream water in three stands was hugh in order of Pinus densiflora (pH 6.59), Castanea crenata(Ⅱ)(pH 6.53) and Castanea crenata(Ⅰ) stand(pH 6.47). The electrical conductivity of stream water was high in order of Castanea crenata(Ⅰ), Pinus densiflora and Castanea crenata(Ⅱ) stand. Cations of three stand in stream water high in order of Ca^2+, Na^+, Mg^2+, K^+ and NH_4^+. But anions of stream water in Pinus densiflora stand and Castanea crenata(Ⅱ) stand were high in order of SO_4^2, Cl and NO_3. In Castanea crenata(Ⅰ) stand cations of stream water were high in order of NO_3, SO_^2 and Cl. The level of pH, NH_4^+, NO_3, Cl and SO_4^2 of stream water in Pinus densiflora stand and Castanea crenata(Ⅱ) stand reached within the level of domestic use standard for drinking water But the level of NO_3 of stream water in Castanea crenata(Ⅰ) stand was higher than that of domestic use standard. Therefore, non-point sources like forest watersheds which are fertilizer application lands should be taken to the appropriate mitigation measures.

Effect of ER signal peptides (KDEL) on expression and function of anti-virus monoclonal antibody in plant

Da-Young Park,Yangkang So,Kyung-Jin Lee,Zhe Lu,Eun-Yi Oh,Kwang-Wok Min,Seul-Ki Lee,Jung-Hwan Lee,Mi-Hyun Ahn,Mira Song,Doo-Byoung Oh,Youngkwan Kim,Kisung Ko 한국당과학회 2009 한국당과학회 학술대회 Vol.2009 No.1

Plant genetic engineering has led to the production of plant-derived mAb (mAbP), which provides a safe and economically feasible alternative to the current antibody expression systems. In this study, the expression levels of mAbP SO57 with or without ER-signal peptides (Lys-Asp-Gly-Leu;KDEL) in transgenic tobacco plants were analysed in transgenic plant. PCR and Reverse Transcription-PCR analyses showed existence of heavy and light chain genes of mAb with or without KEDL and their transcription in plant, respectively. Western blot showed that the expression levels of mAbP SO57 with KDEL were significantly higher than that without KDEL. Flow cytometry analysis showed that the Fc domains of both purified mAbP and mammalian-derived mAb have similar binding activity to the FcγRI receptor. High-performance liquid chromatography analysis showed that the mAbP SO57 with KDEL had glycan profile with both oligomannose and golgi type, whereas the mAbP SO57 without KDEL had only golgi type glycans. Neutralizing analysis with rabies virus CVS-11 showed the similar neutralizing activity between mAbP SO57 with and without KDEL. These results suggest that the potential of mAbP SO57 for rabies immunotherapy is regardless of plant specific glycan structures.

A case of idiopathic hemihypertrophy with hemihypertrichosis

( So Hee Park ),( Do Hyeong Kim ),( Wonkyung Lee ),( Jeong Nan Kang ),( Jung Eun Seol ),( Hyojin Kim ),( Ho Suk Sung ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

A 4-year-old boy had hemihypertrophy and hemihypertrichosis on his left leg since he was 10 months old. Any other family history or past medical history was not noted. The circumference of left calf was 2cm thicker than right calf, and magnetic resonance image also showed hypertrophic muscles. Folliscopic image revealed increased density and thickness of hairs on his left calf. No other systemic abnormalities were detected. The patient was diagnosed idiopathic hemihypertrophy with hemihypertrichosis. Hemihypertrophy is a rare congenital abnormality, showing a fast growth of one side of the body. It usually accompanies diseases such as Beckwith- Wiedemann syndrome, Silver-Russell syndrome, Proteus syndrome. Hypertrichosis shows excessive growth of body hair over the normal range. Three types of congenital hypertrichosis were reported, congenital hypertrichosis lanuginosa, congenital hypertrichosis terminalis and nevoid hypertrichosis. Nevoid hypertrichosis is similar to hypertrichosis in our patient. Co-presence of hemihypertrophy and hemihypertrichosis is very rare and the etiology is unclear. 4 cases of hemihypertrophy with hemihypertrichosis without any abnormalities, so-called idiopathic hemihypertrophy with hemihypertrichosis, were reported. It needs further evaluation to determine whether this condition is a just incidental coexistence or a new syndrome. Herein, we report a case of idiopathic hemihypertrophy with hemihypertrichosis.

다중지능이론을 적용한 디자인 교육활동이 유아의 지능에 미치는 영향

박소연(Park So Yeon),송민정(Song Min Jung) 한국디지털디자인협의회 2012 디지털디자인학연구 Vol.12 No.4

현대사회는 탁월한 성취, 창의성 등을 두루 갖춘 창조적인 인재상을 추구한다. 이에, 창의적 인재양성을 위한 창의적 교수학습법이 화두가 되고 있다. 창의적 교수학습법의 일환으로 창의성, 자율성, 개별화 교육, 자기주도적 학습 등이 핵심 키워드로 거론되고 있으며, 이는 획일주의 교육에서 벗어나 다차원적 관점에서 바라보는 다양한 교육방법의 필요성과 중요성이 있음을 시사하고 있다. 이에 본 연구에서는 개인차 고려, 통합교과과정 적용, 학습자중심 교육을 지향하는 다중지능이론을 적용한 교수학습안을 설계하고, 학습자에게 적용 후, 학습자에게 미치는 영향에 대해 알아보고자 한다. 다중지능이론은 Howard Gardner박사가 정립한 것으로, 인간의 지능은 총 8가지 언어지능, 논리수학지능, 시각공간지능, 자연탐구지능, 개인내적지능, 대인관계지능, 음악지능, 운동지능 등으로 측정?평가할 수 있다고 한다. 그는 다중지능이론을 통해 획일화된 교육이 아닌 개인차를 고려한 학습자중심 교육의 접근법이 이루어져야 한다고 주장한다. 특히 유아의 다중지능 특성을 유아기 초기부터 발견하고 이에 적합한 개별교육이 수행된다면 유아의 흥미와 자아를 존중하는 전인교육이 수행되는 것이며 이러한 교육을 받은 유아들은 미래 사회에서 자신만의 쟁력을 갖춘 성인으로 성장할 수 있다고 지적하고 있다.1)유아교육과정의 원리요소 미루어 보아 놀이 개념의 디자인 중심 학습활동이 유아의 흥미 및 동기유발, 통합적 교과과정의 원리 측면에서 효율적인 교육적 도구가 될 수 있다. 이에 본 연구는 다중지능이론에 근거한 유아 디자인프로그램 및 교수학습안을 만들어 프로그램 적용 전?후의 결과를 비교함으로써 첫째, 유아의 디자인 교육의 필요성과 중요성에 대해 알아보고, 둘째, 다중지능이론을 적용한 디자인프로그램이 유아의 각 지능에 미치는 영향에 대해 살펴보고자 한다. In the modern society, a variety of sciences and technologies are fused to create new knowledge and value. Because of it, a creative teaching-learning method is continuously mentioned for cultivation of creative talent. Recently, creativeness, approach centered on learners and self-directed learning all of which are being emphasized in educational circles strongly indicate that each individual needs to aggressively introduce their own multiple intelligence profiles for teaching-learning process. It is the very Multiple Intelligence Theory developed by Howard Gardner that has suggested a new direction for education. He not only defined the human intelligence as standardized and single intelligence from the cognitive viewpoint but also categorized it into the total 8 fields intelligences. Howard Gardener points out that if the nature of children’s multiple intelligence can be found from early childhood and the individual education appropriate to it is to be carried out the so-called whole-rounded education respecting their interest and egos will be accomplished and those children receiving the education will grow to adults with their own competitiveness in the future. Through design education among children’s learning domains, children can find out the designs which are everywhere in our daily lives, explore the possibility of various expressions and have both convergent and divergent thoughts. Accordingly, the design education is an excellent teaching medium to make children expand the width of thought and cultivate the logic thought. Thus, for this study, a program for children’s design activities by applying Multiple Intelligence Theory will be made to figure out what influence it will have on children’s multiple intelligences.

한 대학한방병원에 입원한 뇌졸중환자의 입원경로를 중심으로 한 기술역학적 고찰

김송,박종,김기순,이철갑,류소연,정영 조선대학교 부설 의학연구소 1998 The Medical Journal of Chosun University Vol.23 No.2

To find the characteristics of stroke patients and the relation between the pathway of admission and characteristics, of the patients including general characteristics, progression of disease and subjective complaints, an analysis was made from the medical record of 291 inpatients due to stroke admitted to a oriental medicine university hospital in 1997. 1. Diagnosis categories of analyzed Patients were 50 cerebral hemorrhage and cerebral infarction. 2. Sex distribution of patients showed 125 male and 165 female and age distribution showed peak 33.7% at 60-69 year old group, 26.5% at 70-79 year old group in descending order(p<05). 3. Thirty four percent of stroke patients had family history of stroke and male showed significantly higher rate of family history of than female(p<05). 4. The type of physical constitution was classified as Tea-Eum-In(太陰人) 43,6%, So-Eum-In(少陰人) 29.9%, So-Yang-In(少陽人) 26.1%, Tea-Yang-In(太陽人) 0.3% in descending order of frequency. 5. Hypertension was the preceding condition for 36.4% of cerebral hemorrhage and 42.7% of cerebral infarction. 6. Sixty nine point four percent of the patients of the patients suffered from the stroke for the first time and 25.4% for the recurred stroke. Major subjective complaints of the patients were motor disturbance, speech difficulty and headache in descending order. 7. As the institution for medical care to this admission, 138 person(47.4%) used western type hospital or clinics, 137 persons(47.1%) passed oriental medicine clinics or hospitals, 6 persons(2.1%) used both type of western medicine and oriental medicine and 10 person(3.4%) used pharmacy folk medicine. 8. As pathway of medical care for cerebral hemorrhage 71.2% of patients used western type hospital or clinic and 26.9% used oriental type of care where as for cerebral infarction 42.3% used western type and 51.5% used oriental type. 9. While admitted to this hospital within one day after occurrence of the disease used oriental type by 87.5% and western type by 14.3%, patient admitted in one week after occurrence of the disease used western type by 66.9% and oriental type by 27.1%. The above results showed that the pathway of medical care for the stroke patients was complicated and make many problems due to delay in the arrival to medical care. So effective health care delivery system for the stroke patients must be made for more efficient medical care.

Interacelluar reprogramming of expression, glycosylation, and function of plant-derived anti-virus therapeutic monoclonal antibody

Da-Young Park,Kyung-Jin Lee,Yangkang So,Zhe Lu,Seulki Lee,Jung-Hwan Lee,Seung Han Oh,Yeon Soo Han,Doo-Byoung Oh,Youngkwan Kim,Kisung Ko 한국당과학회 2010 한국당과학회 학술대회 Vol.2010 No.1

Plant genetic engineering has led to production of plant-derived mAb (mAbP), which can provides a safe and economically effective alternative to the conventional antibody expression methods. In this study, the expression levels of mAbP SO57 with or without ER-retention peptide extensions signal (Lys-Asp-Glu-Leu; KDEL) in transgenic tobacco plants were analysed in transgenic plant. The expression levels of mAbP SO57 with KDEL were significantly higher than that without KDEL regardless of transcription level. mAbP SO57 with KDEL localized surround to the nucleus suggesting that the mAbP with KDEL is localized in ER. The mAbP without KDEL and mAbH had mainly Golgi type glycans, whereas the ER-localized mAbP with KDEL had glycan profile with both oligomannose type (47.6%) and Golgi type (52.4%). The Fc domains of both purified mAbP (with and without KDEL) and human-derived mAb (mAbH) had similar bingding activity to the Fcγ RI receptor (CD64). Both mAbP (with and without KDEL) had a shorter half-life than mAbH. However, both mAbP with and without KDEL was as effective at neutralizing activity of the rabies virus CVS-11 as the mAbH. These results suggest that ER localization of recombinant mAbP by KDEL reprograms glycosylation and enhances production of the functional antivirus therapeutic antibody in the plant.

암환자에게 제공된 다빈도 간호중재 분석 : 5개 종합병원을 중심으로

문경희,안미정,김필자,박정연,김명애,박인숙,배수현,이소정,권인각,김소선 병원간호사회 2009 임상간호연구 Vol.15 No.1

Purpose: The purpose of this study was to identify nursing interventions frequently used with cancer patients. Nursing records from 5 general hospitals for patients with stomach, liver, lung or colon cancer were analyzed. Method: A descriptive study methodology was used and nursing records for 15 patients in each disease category at each hospital, who were admitted and discharged during June 2007 were analyzed. Results: Five domains of NIC were found and the physiological(basic) domain was most frequent (31.52%). Twenty two classes of NIC were identified with risk management for safety being most frequent (22.49%). For the 119 nursing interventions identified, the most frequent was pain management with 7,827 (12.31%), followed by prevention of falls (11.76%), surveillance (6.79%) and wound care (5.12%). Nursing activities of pain management and prevention of falls were comparable to activities listed in literature on guidelines for evidence based and best practices in nursing care. Eight of the 17 nursing activities for pain management, and 9 of 14 for fall prevention were consistent with these guidelines. Conclusion: In this study, nursing interventions were found to be focused on physical care, monitoring patients' condition and education. We have to develop diverse nursing interventions and a convenient recording process.

흡연에 의한 급성 호산구성 폐렴 2예

박종빈,김학렬,주현준,유태양,신성남,신정현,송정섭,황기은,김소영,양세훈,정은택 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

최근 흡연을 시작한 젊은 성언에서 급성 호산구성 폐렴의 발생에 대한 증례가 보고되고 있다. 급성 호산구성 폐렴은 대개 발열을 동반하기 때문에 초기에는 감염성 폐렴으로 잘못 진단, 치료되는 경우가 많다. 아직 정확한 병태 생리 및 조직학적 소견은 밝혀져 있지 않지만 병력 청취 및 임상 양상, 방사선 소견의 관찰을 통해 급성 호산구성 폐렴을 의심하고, 진단을 위해 기관지 폐포 세척액 검사를 시행한다면 좀 더 쉽게 진단 내릴 수 있을 것이다. 본 저자들은 최근 처음 시작한 흡연에 의해 발생한 급성 호산구성 폐렴을 진단하고, 스테로이드를 투여하여 성공적으로 치료한 환자 2예를 경험하였기에 이를 문헌 고찰과 함께 보고하는 바이다. Acute eosinophilic pneumonia(AEP) is characterized by acute febrile respiratory illness associated with diffuse pulmonary infiltration and pulmonary eosinophilia. The specific etiology for acute eosinophilic pneumonia is elusive. By some investigators, cigarette smoking is suggested as a causative substance which can cause AEP. In recent, the authors experienced two cases of AEP following cigarette smoking. Both cases had characteristic features including age around 20 years, new onset smoking before occurance of AEP, diffuse infiltration on chest radiography, pulmonary eosinophilia based on bronchoalveolar lavage and acute improvement after steroid therapy. These clinical features are resemble with previous smoking induced AEP case reports. Base on these clinical features, cigarette smoking associated AEP could be diagnosed more easily.

급성췌장염을 동반한 특발성 양측성 횡격막 마비 1례

박주경,소정일,류진호,김성근,허탁,민용일 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.4

Bilateral diaphragmatic paralysis(BDP) is a rare disorder, which can be secondary to spinal cord injury, motor neuron disease, myopathy, noninfectious polyneuropathy, infection, iced saline cardioplegia performed during cardiac surgery, or idiopathic causes. There may be typical presentations such as dyspnea, paradoxical respiratory movement, and hypercapnic respiratory failure. It needs to exclude above secondary causes to consider idiopathic bilateral diaphragmatic paralysis. We report a 51-years-old man who presented with idiopathic bilateral diaphragmatic paralysis combined with acute pancreatitis. We couldn't find out the association of these two clinical conditions. The patient was improved by mechanical ventilation.

측두골의 거대한 판간내 표피양 낭종 1예

박소영,정대건,김병국,김정묵 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.11