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      • 마이크로 어셈블리용 6자유도 정렬기의 기구학적 분석 및 디자인

        유용환,이문구,이수훈,홍민성,송준엽,이창우 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

        This work will develop a 6-DOF precision aligner with small size and high resolution for assembling the micro parts for a mobile electronics. Here, Tiny PicomotorTM actuator that is small and reliable will be applied to this aligner system. The principle of this actuator is PZT that turns a precision thread and then the screw moves linearly. Arrangement of actuators will be a symmetrical based on kinematic design. This paper presents combining two modules of mechanism for the 6-DOF precision aligner. The first is a stage which can control XYθz motion, and the second can control Z motion, in other words, Z tilt motion. According to its specifications, it is expected to satisfy requirement of precision.

      • KCI등재

        자기조절초점과 제품유형이 비교 광고 노출에 따른 소비자 반응에 미치는 영향

        여준상,송환웅 한국방송광고공사 2007 광고연구 Vol.0 No.77

        Although many researches addressed the effectiveness of comparative advertising, the results of comparative ad. effects compared to non-comparative ad. were mixed and the researches on the reason of this complexity were little. Thus, this research applied self-regulatory focus and hedonic-utilitarian framework which are discussed frequently in recent years to explore the moderating role on comparative ad. effects, and predicted that persuasion knowledge would play roles as a potential mediator. 2(type of ad.: non-comparative/comparative) × 2(regulatory focus: promotion/prevention) × 2(type of product: hedonic/utilitarian) between subjects ANOVA demonstrated supports for our predictions. In case of the interaction hypothesis between ad. type and regulatory focus, subjects in promotion focus condition activated little persuasion knowledge about comparative ad., so the difference of post-exposure attitude between non-comparative ad. and comparative ad. was little. However, subjects in prevention focus condition activated much persuasion knowledge about comparative ad., so the attitude after exposed to non-comparative ad. was more positive than comparative ad.. In case of the interaction hypothesis between ad. type and product type, subjects in hedonic product condition activated little persuasion knowledge about comparative ad., so the difference of post-exposure attitude between non-comparative ad. and comparative ad. was little. However, subjects in utilitarian product condition activated much persuasion knowledge about comparative ad., so the attitude after exposed to non-comparative ad. was more positive than comparative ad.. 비교 광고의 효과성에 대한 논의는 지속적으로 이루어져 왔지만 기존의 비교 광고 연구를 살펴보면 일반 광고와 비교 광고 간의 효과 차이에 대한 의견이 혼재되어 있으며, 그러한 혼재 이유에 대해 명확한 설명을 해주는 연구가 많지 않다. 이에 본 연구는 일반 광고와 비교 광고에 대한 반응에 있어 조절적 영향을 미치는 요인을 찾기 위해 최근 사회 심리학과 소비자 행동에서 많이 논의되고 있는‘자기조절초점(self-regulatory focus)’과‘쾌락(hedonic)-실용(utilitarian) 제품유형’을 적용하였으며, 결과를 설명해주는 잠재적 매개 변수로‘설득지식(persuasionknowledge: 상술지각)’을 예상하였다. 2(광고유형: 일반 광고/비교 광고) × 2(조절초점: 촉진/방어) × 2(제품유형: 실용/쾌락) 집단 간 디자인의 실험 결과, 대부분의 결과가 가설과 일치되는 방향성을 보였다. 구체적으로 살펴보면, 우선 광고유형과 조절초점 간 상호작용 가설의 경우, 촉진초점에서는 비교 광고에 대한 설득지식 활성화가 약하여 일반-비교 광고 간 소비자 반응(광고태도, 브랜드 태도)에 차이가 없으나 방어초점에서는 비교 광고에 대한 설득지식 활성화가 강하여 비교 광고에 비해 일반 광고 노출 후 소비자 반응이 더 좋게 나타났다. 그 다음으로 광고유형과 제품유형간 상호작용 가설의 경우, 쾌락적 제품에서는 비교 광고에 대한 설득지식 활성화가 약해 일반-비교 광고 간 소비자 반응에 유의한 차이가 없으나 실용적 제품에서는 비교 광고에 대한 설득지식 활성화가 강해 비교 광고에 비해 일반 광고에 노출되었을 때 소비자 반응이 더 좋게 나타났다.

      • 방사선치료 조사영역 내에 발생한 설암 환자에서 입체조형방사선치료 경험 : 증례보고

        조문준,장지영,김기환,김병국,송창준,김준상,김재성 충남대학교 암연구소 2003 암연구소 업적집 Vol.3 No.-

        Objectives : We report an interim result of conformal radiotherapy in a patient with early stage cancer at the base of the tongue, which developed in a previously irradiated area. Materials and Methods : A 64-year-old male patient was diagnosed with T4NOMO supraglottic cancer. He received 72Gy of radiation therapy from 21 November 1988 to 24 February 1989. He had local failure and underwent a salvage total laryngectomy on 28 August 1989. Subsequently, he did well. In early 1999, he suffered from throat pain. He had a 2.5cm ulcerative mass at the base of his tongue, in the area that had been irradiated previously. Biopsy showed squamous cell carcinoma. After workup, he was diagnosed with base of tongue cancer with T2NOMO. Surgery was not feasible because the morbidity was not acceptable. Since it was difficult to re-irradiate the area with a curable dose using conventional 2D radiation therapy with an acceptable morbidity, we decided to try conformal radiotherapy. We used 7 static beam ports with field sizes from 7×6.4 to 8×8㎠, using 6 and 10MV photons. The fractionation regimen was 1.8Gy, 5 times per week. He received 64.8Gy in 36 fractions from 9 April 1999 to 1 June 1999. Results : In the 21 months since radiotherapy, the patient has not experienced any acute or chronic complications, such as xerostomia. He experienced relief of pain shortly after the start of radiotherapy, showed a complete response, and is still doing well. Conclusion : Conformal radiotherapy can be used to treat cancer that develops within a previously irradiated field, with curative intent.

      • SCOPUSKCI등재

        한국 정상인에서 연령에 따른 뇌혈류분포와 혈류예비능의 변화 : Tc-99m HMPAO SPECT 에 의한 연구

        문대혁,이희경,송호천,이재태,범희승,손혜경,정환정,민정준,김지열 대한핵의학회 1999 핵의학 분자영상 Vol.33 No.3

        Purpose: The aim of this study was to evaluate the normal values of regional cerebral blood flow (rCBF) and cerebrovascular reserve (CVR) in normal children to aged volunteers using Tc-99m HMPAO. Materials and Methods: Thirty four right-handed normal volunteers (20 males, 14 females, mean age 40.3±24.9 years, range 4 to 82 years) were underwent rest/acetazolamide (ACZ) brain SPECT using Tc-99m HMPAO and the sequential injection and subtraction method. rCBF was estimated on the basis of a semiquantitative approach by means of right/left ratio, region/cerebellum and region to whole brain ratios in frontal, parietal, temporal, and occipital lobes, basal ganglia, thalami, and cerebellum. CVR was measured by means of % perfusion increase calculated as % mean count change compared to rest rCBF in each regions. Results: Mean values of right to left ratios range from 1.004 to 1.018. rCBF was highest in cerebellum and lowest in basal ganglia and thalami. Frontal and temporal rCBF decreased while occipital and thalami rCBF increased according to age. No sexual difference of rCBF was noted. Mean CVR was 29.9±12.9%. Mean CVR significantly increased to late teens, and declined thereafter. After 6th decade, CVR in both frontal lobes, left parietal lobe and right basal ganglia decreased significantly with advancing age. There was no sexual difference of CVR. Conclusion: Quantitative assessment of CVR was possible by ACZ Tc-99m HMPAO brain SPECT. It revealed that rCBF and CVR changed according to age in normal Korean volunteers. There was no sexual difference.

      • 방사선치료 조사영역 내에 발생한 설암 환자에서 입체조형방사선치료 경험 : 증례보고

        조문준,장지영,김기환,김병국,송창준,김준상,김재성 충남대학교 암공동연구소 2003 암공동연구소 업적집 Vol.3 No.

        Objectives : We report an interim result of conformal radiotherapy in a patient with early stage cancer at the base of the tongue, which developed in a previously irradiated area. Materials and Methods : A 64-year-old male patient was diagnosed with T4NOMO supraglottic cancer. He received 72Gy of radiation therapy from 21 November 1988 to 24 February 1989. He had local failure and underwent a salvage total laryngectomy on 28 August 1989. Subsequently, he did well. In early 1999, he suffered from throat pain. He had a 2.5cm ulcerative mass at the base of his tongue, in the area that had been irradiated previously. Biopsy showed squamous cell carcinoma. After workup, he was diagnosed with base of tongue cancer with T2NOMO. Surgery was not feasible because the morbidity was not acceptable. Since it was difficult to re-irradiate the area with a curable dose using conventional 2D radiation therapy with an acceptable morbidity, we decided to try conformal radiotherapy. We used 7 static beam ports with field sizes from 7×6.4 to 8×8㎠, using 6 and 10MV photons. The fractionation regimen was 1.8Gy, 5 times per week. He received 64.8Gy in 36 fractions from 9 April 1999 to 1 June 1999. Results : In the 21 months since radiotherapy, the patient has not experienced any acute or chronic complications, such as xerostomia. He experienced relief of pain shortly after the start of radiotherapy, showed a complete response, and is still doing well. Conclusion : Conformal radiotherapy can be used to treat cancer that develops within a previously irradiated field, with curative intent.

      • KCI등재

        원위 경골 간부 골절에서 최소 침습적 경피적 금속판 고정술과 관혈적 금속판 고정술의 비교

        유성호 ( Seong Ho Yoo ),안성준 ( Seong Jun Ahn ),송무호 ( Moo Ho Song ),김부환 ( Bu Hwan Kim ),이민수 ( Min Soo Lee ),박종하 ( Jong Ha Park ) 대한골절학회 2006 대한골절학회지 Vol.19 No.1

        목적: 경골 원위부 골절의 치료에 있어 최소 침습적금속판 고정술과 관혈적 고정술에 대한 비교를 통한 효율성에 대한 연구고찰을 하고자 한다. 대상 및 방법: 2001년 6월부터 2004년 6월까지 경골 원위부 골절에 대하여 수술을 시행한 최소 1년 이상의 추시가 가능하였던 30예 중 최소 침습적 금속판 고정술을 시행한 15예를 A군, 관혈적 금속판 고정술을 시행한 15예를 B군으로 나누어 수술시간, 술 후 재활, 술 후 운동범위, 동통에 대하여 McLennan과 Ungersma의 기준을 이용한 임상평가, 술 후 염증반응에 대한 C-반응성 단백 및 술 후 합병증을 후향적으로 비교 분석하였다. 결과: A군과 B군의 수술시간은 각각 63분 (45∼105)/129분 (80∼120), 능동적 관절 운동가능시기는 8.3일 (6∼14)/15.8일 (13∼21), McLennan과 Ungersma의 기준에 의한 임상평가는 두 군 모두에서 대부분 양호 이상의 결과를 보였으나, B군에서는 보통 1예가 있었다. 술 후 3일, 7일째 각각 시행한 CRP는 A군에서는 4.0 mg% (범위: 0.9∼7.2)/0.5 mg% (0.1∼1.5), B군에서는 7.97 mg% (2.8∼14.6)/1.0 mg% (0.3∼1.6)로 A군에서 조직손상이 적고 회복이 빨랐다. 술 후 합병증으로는 A군에서는 표재성 감염 1예와 5도 이상의 족관절 외반변형 1예가 있었고, B군에서는 표재성 감염 1예, 감염성 불유합 1예와 10도 미만의 족관절 배굴장애를 보이는 경우가 2예 있었다. 결론: 경골 원위부 골절의 수술적 치료에서 최소 침습적 금속판 고정술이 관혈적 고정술에 비해 조직의 염증반응과 합병증이 적고 수술시간 및 술 후 재활 등에서 보다 효율적인 술식으로 사료된다. Purpose: To evaluate the efficacy of the surgical treatment through the comparison of MIPPO vs open plate fixation in the treatment of the distal tibia fracture retrospectively. Materials and Methods: 30 patients with distal tibia fracture from Jun. 2001 to Jun. 2004 were divided into two groups depending on the surgical method. Minimum follow up was 12 months. Group A consisted of 15 patients treated with MIPPO, Group B was 15 patients treated with open plate fixation. The clinical outcomes were evaluated retrospectively from operation time, rehabilitation, ROM, interval change of postoperative CRP to assess postoperative inflammatory reaction, postoperative complications and clinical result with the use of McLennan and Ungersma criteria. Results: There were no significant differences in clinical result by McLennan and Ungersma criteria in both groups. The postoperative 3 days and 7 days CRP were 4.0 mg% (0.9∼7.2)/0.5 mg% (0.1∼1.5) in group A and 7.97 mg% (2.8∼14.6)/1.0 mg% (0.3∼1.6) in group B, shows more minimal tissue injury and early recovery in group A. Operation time in group A was shorter than group B. Normal recovery of ROM was quicker in Group A. In complications, group A showed one superficial infection and one angular deformity and group B showed one superficial infection, one infected nonunion and two ankle stiffness. Conclusion: There were no significant differences in clinical result and bony union. MIPPO technique is superior to group B in view of the minimal tissue injury, complications, operation time and postoperative rehabilitation.

      • KCI등재후보

        담낭 방선균증 1예

        김형수,정진원,김양수,우준희,송현순,류지소,김명환,김남중 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

        저자들은 우상복부 통증과 소화불량을 주소로 내원한 83세 여자 환자에서 국내 최초로 담낭 방선균증을 진단하고 치료 관찰 중으로 이에 문헌고찰과 함께 보고하는 바이다. Actinomycosis is a chronic suppurative and granulomatous disease, characterized by abscess formation, tissue fibrosis, and draining sinuses. Actinomycosis of the gallbladder is very rare and has not yet been reported in Korea. We report a case of actinomycosis of the gallbladder in an 80-year-old women with history of cholelithiasis for 3 years, preoperatively misidentified as gallbladder cancer. Histologic section of the gallbladder showed Gram-positive branching bacilli compatible with actinomyces. After cholecystectomy, the patient received intravenous ampicillin for 4 days, followed by amoxicillin for 4 months thereafter.

      • KCI등재후보

        흰쥐 Kupffer 세포에 대한 Propofol의 작용

        박세훈,지대림,성언기,김희선,송인환,박희영,김준수,이덕희,박대팔 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.4

        Background: Propofol has an antioxidant capacity and can be used for ischemia-reperfusion injury of the liver. However, the effects of propofol on the Kupffer cells have not been establisked. Methods: Kupffer cells were isolated and cultured from male Sprague-Dawley rats. The effects of propofol on the Kupffer cells were evaluated by a phagocytosis assay, TNF-α gene expression, and superoxide anion release after administering propofol in different concentrations on the cultured Kuprrer cells. Results: The latex bead phagocytosis by the Kupffer cells was suppressed when the Kupffer cells were exposed to propofol irrespective of concentrations. Higher propofol concentrations decreased the loss of Kupffer cells after latex bead phagocytosis. Propofol induced TNF-α mRNA expression in the Kupffer cells, but the mRNA expression level after 50㎍/ml of propofol decreased. The pattern of TNF-α mRNA expression induced by propofol was different to that induced by LPS: TNF-α mRNA was expressed continuously in the propofol-treated cells until 16 hours after exposure to propofol, whereas the level of TNF-α mRNA expression induced by LPS was evident after 2 hours and was not found thereafter. TNF-α production after propofol treatment was not higher than that of the control. Formazan presipitation did not show any qualitative differences between cells untreated or treated with propofol concentrations of 0.5, 5.0, and 50 ㎍/ml. Conclusions: These results showed that propofol might inhibit Kupffer cells. This suggests that propofol and be used for patients with ischemia-reperfusion injury of the liver. (Korean J Anesthesiol 2002; 43: 475~484)

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