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손석호,오명훈,최현화,오병택,김병섭,강동재,Son, S.,Oh, M.H.,Choi, H.H.,Oh, B.T.,Kim, B.S.,Kang, D.J. 한국전자통신연구원 2017 전자통신동향분석 Vol.32 No.4
지능 정보 사회의 도래와 함께 클라우드 컴퓨팅은 정보통신기술 전반을 융합하는 주축으로 자리 잡았다. 다양한 클라우드 컴퓨팅 인프라가 새롭게 구축되고 있으며, 새로운 클라우드 서비스들도 끊임없이 쏟아져 나오고 있다. 그러나, 클라우드 환경과 서비스가 다양해질수록, 운용에 대한 복잡성 또한 증가한다. 클라우드 서비스 브로커리지(CSB: Cloud service brokerage) 플랫폼은 사용자에게 다양한 클라우드 서비스에 대한 검색, 배치, 사용 및 관리 환경을 제공하여 통합된 멀티 클라우드의 접점을 제공하는 시스템으로, 복잡한 이종 환경의 서비스에 대하여 단순하고 일관된 사용 환경을 제공함으로써 서비스 생태계를 활성화하는 기술이다. 본고에서는 CSB 플랫폼의 개념과 기술 구조를 설명하고, 기술 동향과 더불어 국내외 표준화 동향에 대해 살펴본다.
손석호,유승아,남기수,오선화,이경민,이재연,신인철 한국통합생물학회 2022 Animal cells and systems Vol.26 No.5
Brain type of creatine kinase (CKB) regulates energy homeostasis by reversibly transferring phosphate groups between phosphocreatine and ATP at sites of high energy demand. Several types of cancer cells exhibit upregulated CKB expression, but the function of CKB in cancer cells remains unclear. In this study, we investigated the function of CKB in breast cancer by overexpressing CKB in MDA-MB-231 cells. The overexpression of CKB did not affect cell growth rate, cell cycle distribution, ATP level or key mediators of aerobic glycolysis and lactate dehydrogenase isoform levels. Meanwhile, CKB overexpression did increase resistance to doxorubicin. TGF-β-induced Smad phosphorylation and Smad-dependent transcriptional activity were significantly up-regulated by CKB expression without changes in inhibitory Smad protein levels. Moreover, treatment with TGF-β considerably enhanced cell viability during doxorubicin treatment and decreased doxorubicin-induced apoptosis in CKB-expressing MDA-MB-231 cells compared to control cells. These results suggest that CKB attenuates doxorubicin-induced apoptosis and potentiates resistance to doxorubicin by enhancing TGF-β signaling in MDA-MB- 231 cells.
손석호 대한영상의학회 1993 대한영상의학회지 Vol.29 No.2
During a 12-month period high-resolution, real-time ultrasonography (US) with graded compression was performed on 268 consecutive patients with clinically suspected acute appendicitis and its complications. US visualization of a fluid-filled, non-compressed appendix or a decompressed, thick-walled appendix was the primary criterion for a diagnosis of acute appendicitis. The sonographic ficdings were correlated with surgical-pathologic outcome in 92 cases and with the findings of clinical follow-ups in the remainder, US was found to be accurate in the diagnosis of acute appendicitis and its complication with a sensitivity of 93.3%, a specificity of 98.9% and an accuracy of 9.7%. The predictive value of a positive test was 97.7%, that of a negative test was 96.7% There were two false-paositive examinations in patients with a thick-walled appendix or periapperdiceal abscess, which were six false-negative examinations in patients with a sonographically no-visible appendix, which were confirmed surgically as acute appendicitis (n=5) and perforated appendicitis (n=1). Our results show that high-resolution, real-time US is an accureate imaging modality in the diagnosis of acute appendicitis and the evaluation of its complications.
Application of Vacuum-Assisted Closure Device in Management of Postpneumonectomy Empyema
손석호,최세훈,김영태,강창현 대한흉부외과학회 2013 Journal of Chest Surgery (J Chest Surg) Vol.46 No.2
A 57-year-old man was diagnosed with lung cancer and underwent pneumonectomy and mediastinal lymph node dissection. He was discharged without acute complications, but on a regular outpatient follow-up, he was readmitted with postpneumonectomy empyema. He was successfully treated with a vacuum-assisted closure device and for 1 year period of outpatient follow-up, there was no recurrence of empyema or lung cancer.
새로운 소결 방법으로 제조된 n형 $\textrm{Bi}_{2}\textrm{Te}_{2.4}\textrm{Se}_{0.6}$열전재료의 특성
손석호,장경욱,이동희,Son, Seok-Ho,Jang, Gyeo-Uk,Lee, Dong-Hui 한국재료학회 1997 한국재료학회지 Vol.7 No.5
열전재료 분말을 AI관에 진공봉입하고 형틀가입한 후 소결하는 새로운 방법으로 n형 B $i_{2}$T $e_{2.4}$S $e_{0.6}$를 제조하여 소결조건에 따른 소결성과 열전특성을 조사.분석하였다. AI은 소결시 열전재료와 반응하지 않아 보호 용기로 적합하였으며, 평균입도 195$\mu\textrm{m}$의 분말을 사용하여 성형압 280 MPa, 온도 400에서 50$0^{\circ}C$에서 소결할 경우 성능지수는 1.9x $10^{-3}$K였다.다.