한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

성악골 절제후 유리피판술을 이용한 상악재건 3례 보고

박정일,한태근,최준,백세민 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.1

Malignant tumor of the head and neck can be treated by radical excision of the lesion. But the resultant facial deformity acts as a handicap in the patient's life. The quality of life is as important as the quantity. Therefore reconstruction of these patients is an important field in plastic surgery. We used 3 kinds of flap for reconstruction after maxillectomy. Two cases were late reconstruction with Rectus Abdominis myocutaneous free flap and parascapular free flap respectively. In remaining one case, immediate reconstruction was performed with rib bone graft and Latissimus Dorsi free flap. The results were satisfactory. But we found that ptosis of the flap is problem in all cases.

유산균들의 콜레스테를 저하성, 내산성, 내담즙성, 항생제 내성 비교

박소영,고영태,정후길,양진오,정현서,김영배,지근억 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.3

기능성 요구르트의 제조에 사용되는 유산균은 인체에 유익한 생리활성과 우수한 생존능력을 보유하고 있는 것이 바람직하다. 본 연구에서는 다양한 유산균주의 산과 담즙 및 항생제에 대한 내성을 조사하였으며 in vitro에서 콜레스테롤 저하능을 조사하였다. In vitro에서 콜레스테롤 저하능이 우수한 13균주를 선발하여 이들의 동결건조 분말을 고 콜레스테롤 식이의 실험쥐에 투여하였다. 그 결과 8균주는 비 투여구보다 유의적으로 18.3~27.3%의 콜레스테롤 저하능을 나타냈다(P≤0.05). 이들 중에서 Bifidobacterium infantis AM-220, Lactobacillus AM-245, Streptococcus MA-1의 3균주를 이용하여 요구르트를 제조한 후 동결건조 분말을 이용하여 급여실험을 수행한 결과, 총 콜레스테롤과 LDL 함량이 유의적으로 감소하는 것으로 나타났다. For a probiotic yoghurt it is desirable to utilize lactic acid bacteria with a high survival rate and beneficial function to human beings. We have examined a variety of lactic acid bacteria to assess the acid and bile tolerance and antibiotic resistance. In addition, an in vitro culture experiment was performed to evaluate their ability to reduce cholesterol levels in the growth medium. Thirteen strains were selected from in vitro cholesterol assays and fed to Sprague-Dawley rats with a high-cholesterol diet. Among the 13 strains tested, 8 strains were shown to reduce serum cholesterol levels significantly after 24 days of administration in vivo. Rats were fed lyophilized yoghurt powder fermented with a combination of 3 selected strains: Bifidobacterium infantis AM-220, Lactobacillus AM-245, and Streptococcus MA-1. The levels of total cholesterol and low density lipoprotein were significantly lower (p≤0.05) in rats fed the yoghurt powder compared with control group. These studies suggest that yoghurt fermented with appropriately selected lactic acid bacteria may have a anticholesterolemic effect.

장기간 항경련제 투여 환자에게서의 신경전도 속도

박영춘,이동국,임정근,이상도,이형 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

This study was performed to verify whether or not chronic anticonvulsants therapy(≥12 months ) is associated with peripheral nerve dysfunction in epileptics. Nerve conduction studies were done to 51 epileptics who had been taking long term anticonvulsants therapy over 12 months. The mean age of epileptics was 23 years, and was composed of 29 men and 22 women. The mean nerve conduction velocity(NCV) was not significantly different between epileptics and controls. Compared phenytoin or carbamazepine monotherapy group with controls, the NCV was not significantly different in two groups respectively. In epileptics, the mean NCV was not significantly different between phenytoin and carbamazepine monotherapy group. There was no significant relationship between NCV and duration of therapy with either phenytoin or carbamazepine. In epileptics with phenytoin combined therapy, the mean median sensory NCV was significantly delayed than in those with phenytoin monotherapy.

내시경으로 치료한 담석성 췌장염을 동반한 담도회충증 1예

박영주,김영수,최원,신용운,이돈행,김범수,전정배,조현근 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.4

소아기 뇌졸중 후 발생한 간질에 대한 임상적 관찰

박현주,정경중,김근모,김병주,우영종,이정길,김재휴 대한간질학회 1998 대한간질학회지 Vol.2 No.1

간질환자에서 장기간 항 경련제 치료시 뇌간청각유발전위의 변동

박영춘,이동국,임정근,이상도,이형 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.2

저자들은 만성적인 항경련제 투여가 간질환자들의 청신경계에 미치는 영향을 조사하기 위하여 장기간(12개월 이상)항경련제를 복용한 간질환자 51례를 대상으로 이학적 진찰 및 BAEP검사를 실시하고 정상인의 성적과 비교하여 다음과 같은 결과를 얻었다. 장기간 항경련제를 복용한 간질환자의 BAEP검사의 평균 절대 및 파간잠복기는 대조군과 비교하여 유의한 차이가 없었다. Phenytoin단독투여군의 절대 및 파간잠복기는 대조군에 비해 유의한 차이가 없었다. Carbamazepine단독투여군의 I-III파간잠복기는 대조군과 phenytoin단독투여군에 비해 유의하게 연장되었다(p 0.01). Phenytoin단독투여군과 carbamazepine단독투여군에서 항경련제의 복용기간과 BAEP의 절대 및 파간잠복기사이에는 유의한 관계가 없었다. Phenytoin단독투여군과 phenytoin병합투여군에서 각파의 절대 및 파간잠복기는 서로 유의한 차이가 없었다. 이상의 결과로 볼 때 장기간 항경련제를 복용한 간질환자에서 BAEP의 평균 절대 및 파간잠복기는 정상대조군과 비교하여 유의한 차이가 없었고, 항 경련제의 복용기간에 따른 절대 및 파간잠복기의 유의한 변화가 없는 것으로 생각되었다. This study was performed to verify whether or not chronic anticonvulsansts therapy(≥12 months) is associated with brainstem auditory pathway dysfunction in epileptics. Brainstem auditory evoked potentials were done to 51 epileptics who had been taking long term anticonvulasant. The results were summarized as follows. The mean absolute and interpeak latencies were not significantly different between epileptics and controls. The mean absolute and interpeak latencies were not significantly different between epileptics with phenytoin monotherapy and controls. The mean Ⅰ-Ⅲ interpeak latency of carbamazepine monotherapy was significantly delayed than that of phenytoin monotherapy or controls. There was no significant relationship between latency of BAEP and duration of therapy with either phenytoin or carbamazepine. In epileptics with phenytoin combined therapy, the mean absolute and interpeak latencies were not significantly delayed than those of phenytoin monortherapy.

운동신경원성 질환에 대한 임상적 고찰

임정근,이동국,김광수,이상도,박영춘 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

Clinical features, electromyographic findings and the prognosis were observed in 51 patients (33 men and 18 women) who were diagnosed as acquired motor neuron disease at Keimyung University Dongsan Hospital between Jan. 1985 and Aug. 1992. The mean age at onset in our study was similar to that in several other domestic studies but was younger than that in western studies. The therapeutic effect of L-threonine couldn't be evaluated correctly, but L-threonine may have no effect on the course of MND.

기-액계면 흡착에 의한 계면활성제 및 중금속분리

이근희,남상진,김병조,박경기,박종태,신정호 釜山大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.53 No.-

CTAB에 의한 CuS 침전 미립자의 응집과 기포 흡착특성을 고찰하였다. CTAB의 기포흡착은 Langmuir흡착식을 따르며, 포말간 본체액의 동반을 고려한 회분해석으로부터 구한 흡착열은 3700cal/mol로 나타났다. CTAB에 의한 CuS미립자의 기포흡착은 기포-입자간 충돌흡착으로 설명되었고, 흡착분리에 대한 최적 농도비는 CuS의 최적 응집농도비와 일치하였으며, 그 값은 [CTAB] 대 [CuS]가 0.1로 얻어졌다. 기포에 의한 포집효율은 pH와 CTAB농도 등에 의존하나 공기의 유량에는 무관하였으며, 최대 포집효율은 최적 첨가농도에서 0.0002로 나타났다. 또한 Cu-Cd-Zn 황화물의 혼합계에서 CTAB를 사용한 기포흡착의 경우 ZnS의 선택적 분리가 가능하였다. The characteristics of the bubble adsorptive separation of CTAB(cetyltrimethyl- ammonium bromide) and CuS precipitates was investigated. The Langmuir adsorption equation was adequate at very low concentration of CTAB, and the adsorption heat was determined from the batch analysis considering the bulk liquid accompanied between bubbles. The adsorption mechanism was explained with the collision adsorption between bubbles and precipitate particles. The optimum concentration ratio of [CTAB] to [CuS] for adsorptive separation was 0.1 and coincided with the ratio for the coagulation of particles. The collection efficiency was depended on pH and CTAB concentration but not the air flow rate, and the maximum efficiency was 0.0002. The selective separation of ZnS from the mixture of Cu-Cd-Zn sulfides was able by the bubble adsorption with CTAB.

수영만에서 서식하는 해조류의 중금속 함량조사

김정선,차미선,박근태,이상준 부산대학교 환경문제연구소 1999 環境硏究報 Vol.17 No.1