人工甘味料의 合成過程에 對한 再考

박숙자,안송자,유영자,윤정자,윤종은,이명재,정규영,황민자 梨花女子大學校 藥學硏究所 1963 梨花藥學硏究 Vol.- No.4

냉동마쇄고추를 첨가한 깍두기의 저장기간에 따른 이화학적 성분 변화 및 관능적 특성

설민숙,황성연,박소희,이현자,김종군 한국조리과학회 2004 한국식품조리과학회지 Vol.20 No.5

The purpose of this study was to examine the physico-chemical and sensory characteristics of Kakdugi made with mashed red pepper. With regard to the pH of the Kakdugi. those of the juice from Kakdugi with red pepper powder and of the liquid with mashed red pepper were the highest and lowest immediately after preparation. respectively, but thereafter both slightly decreased, but were similar after the fifth week. Generally. the total acidity of Kakdugi liquid was the higher than that of Kakdtegi juice. With regard to the L value, that of the Kakdugi juice was higher than that of Kakdugi liquid and that of Kakdugi with mashed red pepper washigher than that of Kakdugiuitlr red pepper powder. From the third week, the values of all samples generally decreased. The 'a' value of the Kakdugi liquid with mashed red pepper during fermentation was highest During early fermentation, the juice of Kukdugi with red pepper powder showed a higher value than that of Kakdugi with mashed red pepper, but conversely, from the second week that of Kakdugr with mashed red pepper was higher than that of Kakdugi with red pepper powder. The 'L' value of the juice from Kakdugi with red pepper powder was highest until the second week, but trout the third week that of Kalotugi with trashed red pepper was highest. With respect to the organic acids contents, those of citric, quinic and malic acids decreased, but those of lactic and acetic acids increased during tcrrnentatton progression. In addition, the citric, lacticand malic acids contents of the Kakdugi with mashed red pepper werethe highest, whereas that of quinic acid of the Kakdugi with red pepper powder was the highest. From the forth week, the acetic acid content of the Kakdugi with mashed red pepper was further increased. As a result of the sensory test. Kakdugi with mashed red pepper showed significantly higher values with regard to redness and fresh flavor, hut in overall acceptability in the QDA, appearance and taste in the acceptance test. 'Therefore, our results indicate that mashed red pepper particularly increased the 'a' value and organic acid contents of Kakdugi compared to those of red pepper powder, leading to an increased overall acceptability.

전자의무기록의 충실성 검토를 통한 미비기록 개선 활동

조윤정,김경숙,이향숙,이진영,김태민,김민순 한국의료QA학회 2008 한국의료질향상학회지 Vol.14 No.1

문제: 전자의무기록(EMR) 시행 후 의무기록 정리율의 저하와 질적인 측면에서의 충실성과 정확성에 대한 문제점이제기되었다. 목적: 전자의무기록의 정리율과 충실성 검토를 통하여 문제점을 파악하고개선점 찾아 의무기록 정리율을 향상시키고 충실성을 높이고자 하였다. 의료기관: 서울시에 소재한대학병원 의무기록과 질 향상 활동: 전자의무기록의 문제점을 개선히키 위하여 사용자 편의를 위한 EMR프로그램 수정 및 보완, 진단·수술 관련 작업, 업무개선, 교육, 홍보 등의 활동을실시하였다. 개선효과: 의무기록 정리율, 전자인증미비, 경과기록 기재일수, 퇴원요약주진단적합률, 기록지별 필수항목기 재율, 충실성에서 향상이 이루어졌다.

김치유래 젖산균의 균체지방산 분석을 이용한 분류학적 연구

이정숙,정민철,김우식,이근철,김홍중,박찬선,이헌주,주윤정,이근종,안종석,박완,박용하,민태익 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.2

표준균주를 포함한 230여개의 김치유래 젖산균에 대한 균체지방산(FAMEs)을 분석하였다. FAMEs profiles는 Euclidian Distance 17.5에 의해 7개의 Major Cluster와 1개의 Single Cluster로 나뉘어졌다. 이중 A, B, C 및 Cluster는 Leuconostoc속으로 분석되어졌고, F는 Lactobacillus속으로 분석되어졌다. 그리고 E와 G cluster는 두개의 Genus가 혼재되어 나타났으며 보충적인 연구가 필요하다. 앞으로 김치유래 젖산균의 균체지방산 분석결과를 기반으로 한 데이타베이스에 95가지 탄소원을 이용하는 수치분류학적 접근방법 및 Pyrolysis Mass Spectrometry 등의 화학적 분석 방법과 분자친화적 연구를 통한 종합적 분류정보 체계가 갖추어지면 젖산균의 신속, 정확한 동정 및 연구에 활발히 이용되어질 것이다. Two hundreds and thirty lactic acid bacteria, mostly isolated from Kimchi, including type strains were sued for analysis of cellular fatty acids. The 230 test strains were recoverd in 7 major and 1 single clusters defined a Euclidian distance of 17.5. These aggregate taxa were equivalent to the genus Leuconostoc (aggregate group A, B, C and D), and the genera Leuconostoc and Lactobacillus (aggregate group G). It is concluded as evident that FAMEs (Fatty Acid Methyl Esters) profile of cell can be used as a criterion in classification of lactic acid bacterial from kimchi. Additional comparative taxonomic studies need to be carried out on well chosen representative strains to determine the most appropriate methods of value.

초등학생에서 집단따돌림의 유병률과 이와 관련된 정신병리현상

김영신,고윤주,노주선,박민숙,손석한,서동향,김세주,최낙경,홍상의 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.5

연구목적 : 학교폭력의 가장 흔한 형태인 집단따돌림은 피해아동 및 가해아동 모두에서 다양한 행동, 정서 및 사회적 문제와 연관되어 있는 것으로 알려져 있다. 본 연구에서는 지역사회내의 초등학교 고학년 학생들을 대상으로 집단따돌림의 유병률과 집단따돌림과 관련되어 아동에게 나타나는 정신병리 현상에 대하여 조사하고자 한다. 방 법 : 안양지역의 두 초등학교에서 무선으로 선출된 두 학급의 4, 5, 6학년 학생들이 본 연구의 연구대상이었다. 학생들은 한국형 또래지명설문지(K-PNI)를 완성하였고, 교사 및 부모는 ADHD Rating Scale(ARS)과 Conners 척도를 완성하였으며 부모들은 추가로 아동행동조사표를 완성하였다. 통계방법으로는 기술적 통계, 다중회귀분석 및 다중로지스틱 회귀분석을 사용하였다. 결 과 : 총 532명의 학생들이 본 연구에 참여하였다. 집단딸돌림의 피해자, 가해자 및 피해자 겸 가해자의 유병률은 각각 48%, 45%, 30%로 나타났다. 심한 집단따돌림의 유병률은 2.1∼4.1% 사이였다. 집단따돌림의 피해아동와 피해자 겸 가해아동들은 교사와 부모에 의해 부주의하고 수동적이며 사회적으로 미성숙하고 공격성이 있는 것으로 평가되었으며 학년이 올라 갈수록 피해자가 되는 경향이 적은 것으로 나타났다. 가해 아동은 행동문제와 관련되어 있었으며 남아에게 많은 것으로 나타났다. 결 론 : 집단따돌림은 한국 초등학교 고학년 학생들 사이에서 매우 흔하게 일어나는 현상으로 보인다. 집단따돌림의 경험을 한 아동은 그렇지 않은 아동에 비해 더 많은 정신병리 현상을 보였다. 이러한 정신병리와 집단따돌림과의 인과관계를 밝히기 위해서는 집단따돌림을 경험한 아동에 대한 추적 조사가 필요할 것이다. Objective : School bullying, the most prevalent type of school violence, is Know related to various behavioral, emotional and social problems both in victims and per The purpose of the present study is to investigate the prevalence of school bullying psychopathology in a community sample of elementary school students. Method : Fourth to 6^th graders of two randomly selected classes in two elementary Anyang City participated in a cross-sectional study. Study subjects completed Nominating Inventory(K-PNI). Parents completed Korean-Child Behavior Checklist(KADHD Rating Scale(ARS) and Conners Scales for parents, and teachers completed Conners Scales for teachers. Descriptive statistics, multiple linear and logistic regress performed. Results : A Total of 532 students participated in this study. Prevalence of victims, and victim-perpetrators were 48%, 45%, and 30% respectively. Extreme victims and of school bullying ranged from 2.1∼4.1%. Inattention-passivity in teachers' Conn social immaturity or aggression in K-CBCL were positively associated with victims perpetrators, and grade was negatively related to school bullying. Conduct problem in Scale for teachers and emotional instability in K-CBCL, and male gender were positively with perpetrators. Conclusion : School bullying is very common in Korean children of elementary Those who had experienced school bullying, either as victims or as perpetrators, cantly more psychopathology than their counterparts. To clarify a causal relationship psychopathology and school bullying, a longitudinal follow-up study is suggested.

심한 낙타혹(Hump)의 형성을 동반한 제 2 형 막증식성 사구체신염(Dense Deposit Disease) 1예

오희정,유민아,이영숙,김미연,김승정,강덕희,윤견일,최규복,성순희 이화여자대학교 의과대학 2004 EMJ (Ewha medical journal) Vol.27 No.1

Dense deposit disease (DDD), known as type Ⅱ MPGN, is an uncommon form of glomerulonephritis. It is an acquired primary glomerular disease, characterised by electron microscopic evidence of a continous, dense membrane deposition replacing the lamina densa. There is associated alternative pathway complement activation and a C3 nephritic factor maybe present. Patients with dense deposit disease tend to be young at clincal onset and more commonly have persistent nephrotic syndrome, gross hematuria, and acute nephritis episode and persistent depression of the serum complement level. The prognosis of dense deposit disease is worse than that of typeⅠMPGN. We experienced a patient with dense deposit disease that presenting persistent nephrotic syndrome, gross hematuria and having subepithelial hump. It is a first report of dense deposit disease having subepithelial hump in Korea, therefore we report this case with the review of relevant literatures.

냉수 가글링과 젖은 거즈를 이용한 구강간호가 비강수술 환자의 갈증 및 구강상태에 미치는 효과 비교

이인선,심명숙,나은희,강재연,김지혜,황민영,윤계숙,성영희 병원간호사회 2006 임상간호연구 Vol.11 No.2

Purpose: This study researched the comparison of oral care methods between the wet gauze and the water gargling for nasal surgery patients. It executed to find out more effective method to relieve thirst. Method: We divided two groups; the wet gauze and the cold water garaling. We assessed patient's oral cavity state and sebjective oral dryness for three times; firstly before the intervention, secondly 15 minutes after 1st intervention and thirdly 15 minutes afrer 2nd intervention. Result: As the intervention, there was no difference on oral condition subhectvely, but there was a difference on thirsty reduction objectively. As the aral dryness has relieved through both methods. It showed the repeated gargling helps more to relieve oral dryness effectively than the wet gauge. At PACU, post nasal surgery patient's oral dryness was decreased with gauze more than two times, patient's oral dryness was relieved. Whereas the dryness was relieved after applying the cold water gargling for just one time. Conclusion: The water gargling is more effective intervention than the wet gauze. Especially, oral dryness was improved in the section of objetive oral assessment index.

인공 판막 환자에서 발생한 Listeria monocytogenes 심내막염 1예

신상엽,손준성,김형훈,민태훈,윤종욱,장현하,정숙인,오원섭,김성민,백경란,송재훈 대한감염학회 2002 감염 Vol.34 No.5

Immune Cell Signaling(Signal Transduction) : HVEM is released from Leukocyte membrane following activation and gastric cancer patients have high Levels of soluble HVEM in their blood and Low Levels of membrane HVEM on Leukocytes

( Min A Yun ),( Sook Kyoung Heo ),( Sang Min Park ),( Boo Hee Sung ),( Byung Sam Kim ) 한국생화학분자생물학회 (구 한국생화학회) 2008 생화학분자생물학회 춘계학술발표논문집 Vol.2008 No.-

CK20 expression enhances the invasiveness of tamoxifen-resistant MCF-7 cells.

Min, Yun Sook,Yi, Eun Hee,Lee, Jin Koo,Choi, Ji Won,Sim, Ji Hyun,Kang, Jae-Seung,Kim, Yong-Nyun,Juhnn, Yong-Sung,Kim, Hang-Rae,Ye, Sang-Kyu Potamitis Press 2012 Anticancer research Vol.32 No.4

<P>Cytokeratin 20 (CK20) is an intermediate filament that is known to be a prognostic marker in several types of cancer. However, little is known about CK20 expression and tumor metastasis in tamoxifen-resistant MCF-7 (TRM-7) breast cancer cells. TRM-7 cells overexpress CK20, resulting in enhanced invasiveness in vitro. CK20 silencing reduced the invasiveness of TRM-7 cells. Moreover, CK20 expression in MCF-7 cells was regulated by peroxisome proliferator-activated receptor γ (PPARγ). Our findings suggest that PPARγ-dependent CK20 expression enhances the metastatic potential of MCF-7 breast cancer cells and may be a potential therapeutic target in tamoxifen-resistant breast cancer.</P>