Mycobacterium mageritense에 의한 당뇨병성 족부 감염증 1예

김충종,김낙현,김문석,김계형,전재현,박문석,박경운,박완범,박상원,김홍빈,김남중,오명돈,최강원 대한감염학회 2008 감염과 화학요법 Vol.40 No.6

Diabetic foot infection is one of the important complications in patients with advanced diabetes mellitus. Limb threatening infections such as osteomyelitis, abscess, and necrotizing fasciitis are frequently accompanied by the disease. Non-tuberculous mycobacterium (NTM) is a rare causative organism of diabetic foot infection. Thus, if one is not suspicious or meticulous, infection due to NTM will be easily overlooked and this will result in delayed diagnose and treat. Therefore, it is necessary to consider NTM as the causative organism if the wound does not respond to the conventional antibiotic treatment and the culture from the adequately obtained specimen reveals atypical acid-fast bacilli. We present a case of diabetic foot infection with osteomyelitis and abscess due to Mycobacterium mageritense, one of the rapid growing mycobacteria, that was successfully treated with surgical debridement and appropriate antibiotic treatment.

여성 복압성요실금에서 술 전 발살바요누출압에 따른 Suprapubic Arch 술식의 결과

박준명,유지형,성락희,정재용,노충희 인제대학교 2008 仁濟醫學 Vol.29 No.-

Objective : There were variant results for correlation between the postoperative cure rate and valsalva leak point pressure (VLPP) for female stress urinary incontinence (SUI). Therefore the aim of this study was to assess the influence of VLPP on the outcome of suprapubic arch (SPARC) procedure. Materials and Methods : A retrospective analysis was made of 246 women who underwent SPARC procedure for SUI. Based on VLPP, the patients were divided into 2 groups: group A (VLPP<60cmH2O) and group B (VLPP≥60cmH2O). The objective success rate and subjective success rate were assessed. Before surgery, the patients were evaluated with history taking, physical examination, urinalysis and urodynamic studies. The objective success rate was evaluated by clinical examination and the 1-hour pad test postoperatively and the subjective satisfaction rate was assessed using questionnaires for the patients' satisfaction and evaluated by recommendation rates of SPARC procedure to other patients. The objective success rate included cure and improvement, the subjective success rate included satisfaction and fair. Results : The number of patients in each group was 145 patients (group A) and 101 patients (group B). The objective success rate was 99.3% (group A) vs 98.0% (group B) (p=0.285). The subjective success rate was 98.6% (groupA) vs 98.0% (group B) (p=0.500). Recommendation rates of SPARC procedure was 94.5% (group A) vs 95.0% (group B) (p=0.422). Conclusion : It is our belief that SPARC procedure for female SUI is efficacious and safe regardless of preoperative VLPP.

안정화제 처리된 회수수를 사용한 콘크리트의 특성에 관한 실험적 연구

박영신,박재명,이세현,이문환 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

Recently, Most enterprises produced ready mixed concrete uses a mixing water as a recycling water without a density control in proportion to guide and standard. That is a cause of deterioration in the concrete quality like a reduce of strength, laitance, crack, etc. This study shows basic materials for development of ready mixed concrete recycling water density control system that holds down a deterioration in the concrete quality by using a mixed water treated recycling water with stabilizing agent and examines a possibility of re-using components of cement in recycling water. Therefore, in the experiment, we make a recycling water contains 3,5,7% of solid content ratio examines a property of a mixing water with a stabilizing agent and without it. Results of this study is next as follow. 1. The slump is decreased 1~2cm in a mixing without a stabilizing agent and the mixing with a stabilizing agent is similar to the standard mixing. 2. The air content is 4~4.7% in proportion to an increase of solid content without a stabilizing agent and the mixing with a stabilizing agent is similar to the standard mixing. 3. The compressive strength of an early curing age is tendency to increase both the mixing without a stabilizing agent and the mixing with a stabilizing agent. But, After 14days is passed, Compressive strength is decreased in a mixing without a stabilizing agent but increased a mixing with a stabilizing agent.

이중외피 파사드의 운전모델 개발에 관한 연구

박유영,조재훈,여명석,김광우 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

The objective of this study is to develop the operation model of the double-skin facade for energy conservation and user comfort. This study proposes development process of the operation model in three steps. A case study is used to investigate the feasibility of the process. The G building in Kungkido is chosen. The main contents of this study are as follows. 1) The operation objectives and standards are established. And the operation factors classified according to the objectives and standards. 2) Correlation of the operation factors are clarified. And Individual models. The operation model is essential to building which has the double-skin facade and logical operation would be improved by this model. For the practical application of this operation model, it will be needed to connect the building management system.

임산부에서 발생한 폐크립토콕쿠스증을 동반한 크립토콕쿠스 수막뇌염 1예

박경화,송진수,최평균,방지환,조재현,박완범,김홍빈,김남중,오명돈,최강원 대한감염학회 2006 감염과 화학요법 Vol.38 No.4

Cryptoccus necoformans는 면역기능이 저하된 환자에서 기회 감염을 일으키는 진균이나 정상인에서도 드물게 질병을 일으킨다. 그러나 임산부에서 폐크립토콕쿠스증을 동반한 크립토콕쿠스 수막염의 보고는 아주 드물다. 저자들은 분만 후에도 악화되는 두통과 의식저하로 내원한 임신 37주의 임산부에서 뇌척수액과 폐조직검사를 통해 폐크립토콕쿠스증을 동반한 크립토콕쿠스 수막뇌염을 진단하고 항진균제를 사용하여 치료하였다. 본 증례처럼 명백한 기저질환이 없는 임산부에서도 크립토콕쿠스 수막염은 발생할 수 있으므로 의심이 되면 뇌척수액검사를 포함한 진단적 검사를 시행하고 적절한 치료를 시작해야한다. 그리고 임산부에서 크립토콕쿠스증이 발생한 경우의 치료에 대하여 문헌 고찰과 함께 보고하는 바이다. Cryptoccocosis occurs more frequently in immunocompromised hosts such as patients with AIDS, lymphoma, leukemia and other debilitating diseases. Pulmonary cryptococcosis can occur in the absence of any recognized immunodeficiency and cryptococcal meningitis can occur rarely during pregnancy. Although it is extremely rare, we encounter the reports of case of cryptococcal pneumonia and combined cryptococcal meningitis during pregnancy. We present here that 36-year-old pregnant woman, who was previously healthy, with cryptococcal meningoencephalitis and cryptococcal pneumonia was treated with amphotericin B and flucytosine. The maternal outcome was favorable, and there is no evidence of congenital infection in the newborn.

강성사면에 인접한 옹벽의 거동에 관한 연구

이명욱,유남재,박병수 江原大學校 産業技術硏究所 1998 産業技術硏究 Vol.18 No.-

This thesis is an experimental and numerical research on beating capacity acting retaining walls close to rigid slopes with stiff angles. Experiments were performed with changing the roughness of adjacent slope to the wall, its inclination, distance between wall and slope. Vertical stress and applied surcharge loads were measured by miniature earth cells and a load cel respectively. Stress distribution Vertical Settlement of surcharge of rigid model footing were measured by LVDTs. Bearing capacities of surcharge loads were compared with theoretical estimations by using several different methods of limit equilibrium and numerical analysis. For limit equilibrium methods, the modified silo and the wedge theories, proposed by Chung sung gyo and Chung in gyo(1994) were used to analyze test results Based on those modified theories, the particular solution with the boundary condition of surcharge loads on the surface of backfill was obtained to find the stress distributions acting in the backfill and to compare with test results. From results of surcharge test with model wall being very close to the slope, analyzed results by the modified silo theory and to be in the better agrements than other methods.

과민성 장 증후군의 증상 경감을 위한 비약물적 접근 고찰

최명애,김금순,안경주,채영란,최정안,홍해숙,박미정,이경숙,신기수,정재심 대한기초간호자연과학회 2005 Journal of korean biological nursing science Vol.7 No.2

There have been many trials of clinical efficacy of multicomponent and single component treatments for irritable bowel syndrome(IBS). We reviewed effects of non phamacological treatments in the IBS. Though the efficacy of multi-component approaches was unclear, several results suggest that cognitive behavioral therapy was effective in improving gastrointestinal symptoms of IBS. As a single component, cognitive therapy and relaxation with or without biofeedback could improve the symptoms and psychological health of IBS patients. Yoga, meditation, self-help information and hypnotherapy could be applicable to IBS.

VATER Association 1예

최명재,박영일,김상우,고일향 인제대학교 1986 仁濟醫學 Vol.7 No.4

We have experienced a case of VATER association in a newborn infant who presented with typical anomalies. The diagnosis was made with physical and autopsy findings consisted of anal atresia, tracheoesophageal fistula with esophageal atresia, left radial dysplasia with limb anomalies, right renal agenesis, cardiac anomalies, vesicoperineal fistula, and vesicorectal fistula. Brief review of the related literatures is also presented.

Priming 처리종자의 저장기간에 따른 발아력 전당함량 및 α-amylase 활력

김재현,이석순,박성태,정명근 한국국제농업개발학회 2002 韓國國際農業開發學會誌 Vol.14 No.3

벼 종자의 priming처리 후 저장성을 검토하기 위하여 저장기간과 저장온도에 따라서 종자의 발아력과 저장양분 및 발아에 관여하는 주요 효소활력의 변화를 조사한 결과를 요약하면 다음과 같다. 1. Priming한 종자를 6개월간 저장하여도 어느 저장온도에서나 발아율의 차이가 없었다. 2. Priming한 종자에서 발아속도(T_50)가 2∼3일 빨랐으며 3개월 동안은 변화가 없었고 3개월 이후 발아속도가 약간 감소하였으나 priming 처리하지 않은 종자에 비해서 빨랐다. 3. 발아균일도는 priming 처리효과가 6개월간 계속 유지되었으며 25℃보다 저온인 17℃에서 효과가 더 크게 나타났다. 4. α-amylase 활력은 저장기간이 길수록 높았고 전당함량의 경우 3개월 이상 저장하였을때 감소하였으나 발아력에는 영향을 미치지 않았다. 5. 종자 수확후 6개월 동안은 어느 시기에 priming 처리하여 저장하여도 발아력 및 종자의 활력은 유지되었다. This experiment was carried out to determine changes of seed germination ability, total sugar, and α-amylase activity to different storage period, and temperature after seed priming treatment. In the storage during the six months, final germination rate and speed were similar to the untreated control seeds and the uniformity was continuously preserved. Germination speed(T_50) was faster than the control seeds by 2∼3 days. T_50 was a little decreased to priming effect after three months but faster than the control seeds. In the case of germination temperature 25℃, germination uniformity was decreased to long term storage periods. Total sugar content was increased to compare with the control seed during the one months at -10, 5 and 20℃ and total sugar content was decreased after two months. α-amylase activity was increased to storage of long term period and seed of storage temperature 5℃ was increased compared with -10 and 20℃. Germination ability and α-amylase activity was preserved continuously during six months after priming treatment.

백서 적혈구에서 glutathione이 paraquat 독성에 미치는 영향

김명철,박재윤,채기영,천영욱,박평심,차종희 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.16 No.2

The participation of superoxide in initiating tissue damage from administration of a xenobiotics is best illustrated by paraquat intoxication, in which it is known that one electron reduction of paraquat leads to the formation of radicals which react with molecular oxygen to give superoxide. In the present study, the effects of paraquat on the level of glutathione and activities of superoxide dismutase(SOD), catalase, glutathione peroxidase, glutathione reductase and glutathione stransferase were investigated in rat liver and erythrocytes. The contents of glutathione in liver and blood were sinificantly decreased by paraquat administration, but the activities of enzymes were unaltered. Incubation of the buffered aerobic mixture of erythrocyte in the presence of 5mM glucose, Paraquat and/or N-ethylmaleimide(NEM) resulted in the formation of lipid peroxide, the activities of various enzyme and the levels of glutathione were determined. The malondialdehyde(MDA) contents as a indicator of lipid peroxidation was decreased and the levels of total glutathione were not changed but the levels of oxidized glutathione(GSSG) were in creased in paraquat treated erythrocytes. The activites of ezyme were decreased in paraquat treated erythrocytes but in reduced glutathione(GSH) treated erythrocyte, the enzymes activities were less decreased by paraquat. These results suggest that paraquat toxicity was probably somewhat reduced by GSH, but paraquat-induced injury were not increased by GSH depletion in erythrocytes.