서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

부갑상선 호르몬이 조골세포군의 교원분해효소 유리에 미치는 영향에 관한 연구

이인석,김관식,정동균 대한구강생물학회 1990 International Journal of Oral Biology Vol.14 No.1

Bone resorption is accomplished by the removal of both mineral and the organic matrix. The cellular origin of bone collagenase that is responsible for the removal of unmineralized organic matrix has remained equivocal. This study was performed to investigate the effect of PTH on the release of collagenase and cellular origin of bone collagenase in bone cell populations. Calvaria from fetal rat at 19-day of gestation, were sequentially digested by the enzyme solution consisted of collagenase, trypsin and EDTA for 10 min (PopulationI), 10 min (II), 10 min (III), 20 min (IV) and 20 min (V). Each bone cell population was primarily cultured for 6-7 days and splited to 5.0×10^5 cells/35mm culture dish and then incubated for 6 days with MEM with or without PTH (1.0U/ml). Collected medium was incubated with type I collagen for 6h at 37℃ and then used for hydroxyproline determination by Woessner's method. The results were as follows. 1. There were no significant differences of collagenase activity among 5 bone cell populations. 2. PTH (1.0U/ml) had no effect on the collagenase activity in the population I, II, III and V. 3. PTH (1.0U/ml) significantly increased collagenase activity in population IV.

대전·충남지역 와병노인의 실태에 관한 연구

이동배,심운택,이태용,오장균,정성훈 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.1

This study was conducted to investigate the prevalence rate and the relationship between causative diseases and self-help abilities in bed ridden patients of the elderly. The study group was composed of 1.568 peoples aged 65 or more, living in Taejeon city and Chungnam provincial area. The results obtained were as follows : 1. The prevalence rate of bed ridden patients were 5.7% in male, and 4.3% in female. The rates revealed increasing basis with the ages. 2. The prevalence rate was higher in city area with 6.1% than inland and seaside area with 4.3%, 3.7% respectively. 3. The mean age of bed ridden patients were 75.9 years in male. 78. 0 years in female. The rates were variable with residential area. As the cause of bed ridden patients the cerebrovascular disease was higher in urban than rural area. 4. The mean age of causative diseases was the highest in contusion and fracture with 82.8 years. The period of bed ridding was the highest in muscular disease and arthropathy with 60.2 monthes. 5. The average score of activity of daily living was the highest in muscular disease and arthropathy and followed by respiratory disease, other disease, senility, cerebrovascular disease, contusion and fracture with decreasing basis. But most bed ridden patients did the activity of daily living similar to those of normal persons. 6. The causative diseases were diagnosed mainly in general hospital, hospital. and herb medicine. but muscular disease and senility were in self-diagnosed. 7. The helper of bed ridden patients were mainly wives or daughters in law.

FORMOCRESOL을 이용한 치수절단술시 FORMALDEHYDE의 전신적 흡수 및 급성독성에 관한 연구

이범모,한세현,김관식,정동균 대한구강생물학회 1990 International Journal of Oral Biology Vol.14 No.1

Formaldehyde that is active constituent in formocresol used in pulpotomy is known as toxic agent that causes systemic toxicity. To determine the fate of the ^14C-formaldehyde which was absorbed following its application to pulpotomy sites, by-pass of posterior facial vein and cannulation of external carotid artery were established with 20G-polyethylene tube. Blood samples (0.2ml) were collected in glass syringe before the pulpotomy and then at 0, 3, 5, 10, 20, 30, 45, 60, 90 and 120 minutes thereafter. Plasma was separated after centrifugation at 3000 x g for 15 min and aliquots of plasma were counted by liquid scintillation counter. After liver, kidney, lung ,heart, spleen, muscle, and alveolar socket were removed and solubilized with tissue solubilizer, the radioactivities in solutions were counted by liquid scintillation counter. The acute toxicity of formocresol was determined by BUN, GOT and OCT assay in blood samples collected 0, 2, 4, 6, 9 and 12 hours by means of cardiac puncture. The results were as follows ; 1. The radioactivity of ^14C-formaldehyde reached maximal value at 3-5 minutes and decreased thereafter. 2. About 8% of ^14C-formaldehyde placed in the pulpotomy site was actually absorbed systemically until 2 hours. 3. About 50% of ^14C-formaldehyde absorbed actually was distributed within 20 minutes. 4. The radioactivity of organ per gram was highest in the spleen and lowest in the muscle. 5. Total radioactivity of organ was highest in the liver and lowest in the heart. 6. There were no significant differences between control and experimental groups in BUN, GOT and OCT assay.

흰쥐 Nucleus Raphe Magnus에 투여한 Morphine이 척수 Serotonin 유리에 미치는 영향에 관한 연구

이신재,임요한,최영님,김형룡,정동균 대한구강생물학회 1991 International Journal of Oral Biology Vol.15 No.1

It is known that the interaction between opioid neuron and serotonergic neuron in bulbospinal pathway has an important role on pain control. This experiment was perfomed to directly measure the release of serotonin into spinal cord superfusates before and after the microinjection of morphine and its antagonist, naloxone into the NRM of rats. High performance liquid chromatography with electrochemical detection was used to quantitate the amine. The injection of morphine into the NRM induced a significant increase in the amount of serotonin released in the spinal cord, which was reversed after the intraperitioneal injection of naloxone. These results support the proposal that : the analgesia produced by morphine microinjected into the NRM is mediated by the activation of spinally projecting serotonergic neuron.

기어의 생산성 향상을 위한 피닝공정의 실험적 연구

이재헌,이동선,정성균 서울産業大學校 2005 논문집 Vol.54 No.1

The shot peening process is well known technique for extending the durability of mechanical parts. We can expect the high cost and low fatigue life because the over peening process is applied in the industrial field. In this paper, the improvement of gear productivity was investigated by applying the optimum peening process. The experiment was accomplished for the SCM920 spur gear. Saturation curve and optimum peening condition were obtained by bending fatigue test. Experimental results show that the optimum peening time is between 6 minutes to 10 minutes. The improvement of productivity by optimum peening process was 36% higher than conventional process.

청소년의 스포츠 활동 참가와 스트레스의 관계

이종경,서동균 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

The purpose of this research is to examine how the adolescents participation in sports influences the stress of them, to back up empirically the fact that such mutual relation have an effect on the daily removal and easing of the stress, and further, being based upon this, to present the basic data required for the policies related to the adolescents. Among these, excluding those questionnaires which were judged to lack the reliability, the number of the samples used actually for the analyses was total 427 students including the 237 participating students and 190 nonparticipating students in the sports activities. The tool for the data collection is the "Survey questionnaire regarding the relations batween the sports participation of the adolescents and stress". and as a result of the adolescents of the reliability the stress α = .80 where high coefficients of the reliability have been derived. For the data analysis the SPSS (Statistical Package for Social Science) program has been used in this research, to meet the purpose of this research the frequency analysis, analysis of covariance, multiple regression analysis have been carried out, and the following research results have been derived. First, experience of participation in sports activities influences on stress level of the adolescents. Namely, the participants of sports activities are more low than the non-participants in stress level. Second, degree of participation in the sports activities influence on stress level of the adolescents, Namely, the participation frequencies have negative influence on stress level.

쇼트피닝 가공에 의한 자동차용 Drive Plate의 내구성 향상

이국진,이동선,이재헌,정성균 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

The effects of shot peening on the fatigue strength of SK-5M steel is investigated by experiment. The shot peening process is investigated optimum peening condition by changing impeller speed and exposure time. Bending fatigue test is accomplished to investigate the effect of optimum peening condition on the fatigue characteristics. As exposure time is increased, fatigue life in high stress is increased in early stage, become the maximum from 60 to 100 seconds, and then is decreased. Observing fracture surface through SEM after fatigue test, we can see clear configuration of cracks and peening layer.

Eu를 포함하는 발광 고분자 합성

李愚鵬,吳東元,朴美淑,黃悳海,司空恩,朴在均 慶北大學校 科學敎育硏究所 2004 科學敎育硏究誌 Vol.28 No.-

Poly (9,9-dialkylfluorene-2,7-diyl) derivatives end capped with 2,7-dibromo-9,9-dihexylfluorene and conductive fluorene substituents have been synthesized through Ni(0), the nickel-catalysed reduction with metallic zinc-mediated polymerization. When electron and hole recombined and formed a exciton in emitting layer. Singlet exciton and triplet exciton is the ratio of one to three. One is fluorescence and three is phosphorescence, but phosphorescence is almost sustained a loss. Not only to shift blue region but to increase phosphorescence efficiency, it is substituted Eu for the terminal H in this polymer chain. P1-Eu showed green emission at 533nm while P1 had at 548nm. The main emission peaks of the P1-Eu shift shorter wavelength, besides we observed another emission peaks of the P1Eu at 418nm.

체외충격파 쇄석술 시행 후 5년 뒤 발생한 요관 협착 및 농신장 1예

이현승,권균홍,조용건,김봉진,임창섭,김자영,허동,임학 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

A 40-years-old woman was admitted to this hospital with flank pain and high grade fever for 2 weeks. As a matter of her past history, extracorporeal shock wave lithotripsy (ESWL) was performed for treatment of renal stones 5 years ago. Her abdominal CT findings were hydronephrosis with pyonephrosis and renal stones. Antibiotics administered for 5 days had no effects on her symptom improvement. A right ureteral stricture was noticed by ultrasonography follow up. We inserted double J stent and continued antibiotics therapy for 10 days, and then her fever was disappeared and flank pain was improved. ESWL is one of the most important treatment of renal and ureteral stone. However, its complications should not be negligible including bleeding, pain, ureteral obstruction, infection and so on. Complications of ESWL can be divided into acute and chronic courses. When we treat pyelonephritis patient with past history of ESWL, possibility of ureteral stricture must also be considered. In this study we report a case of pyelonephritis caused by ureteral stricture, possibly as a chronic complication of ESWL performed 5 years earlier