Selenium 공급방법이 수경재배 토마토의 생장과 Se 흡수에 미치는 영향

이철규(Cheol-Kyu Lee),조경철(Kyung-Cheol Cho),이정현(Jeong-Hyun Lee),조자용(Ja-Yong Cho),서범석(Beom-Seok Seo),양원모(Won-Mo Yang) (사)한국생물환경조절학회 2005 생물환경조절학회지 Vol.14 No.4

토마토 ‘모모타로’를 공시하여 셀레늄 10㎎ㆍL?¹의 관주 및 엽면시비 등의 단용 및 혼용처리가 수경재배 토마토의 생육 및 과실 내 셀레늄 축적 함량에 미치는 영향을 구명하였다. 토마토 종자를 50공 트레이에 파종하여 70일 동안 육묘한 후 유묘를 코코피트 슬라이브를 이용한 수경재배 시스템에 정식하였다. 양액은 일본원예시험장 배양액 표준처방으로 조성하였으며, pH 5.8~6.2와 EC 2.3 ㎎ㆍL?¹ 등으로 조절하여 공급하였다. 셀레늄은 무기태 SeO₂와 sugar fatty acid ester에 킬레이트화 한 유기태 셀레늄을 10 ㎎ㆍL?¹으로 조성하여 관주, 엽면시비, 관주와 엽면시비를 병행하여 처리하였다. 초장, 엽수, 엽면적 및 엽록소 등의 토마토 생장반응은 셀레늄의 엽면시비, 그리고 엽면시비와 관주를 병행한 처리구에서 현저히 증가하였다. 과실 내 셀레늄 축적 함량은 킬레이트화 한 유기태 셀레늄을 엽면시비와 관주를 병행하여 처리한 경우에 0.302 ㎎ㆍL?¹으로 가장 높았다. 무기태와 유기태 셀레늄의 엽면시비와 관주 등의 단용 처리 보다는 혼용 처리가 전반적인 과실 생장과 체내 셀레늄 축적에 효과적이었다. 무기태 설레늄(SeO₂) 보다는 sugar fatty acid ester에 킬레이트화한 유기태 셀레늄 처리가 셀레늄을 함유한 기능성 토마토의 수경재배에 더 효과적이었다. This study was conducted to clarify the effects of supplying methods of selenium on the growth and Se uptake of hydroponically grown tomato plants. Tomato seeds (Lycopersicum esculentum Mill. cv. Momotaro T-93, Daki Seed Co.) were sown in plug tray with fifty holes, and raised for sixty days. Tomato seedlings transplanted to coco fiber slabs were supplied with the nutrient solutions adjusted to EC 2.3 dSㆍm?¹ and pH 5.8~6.2 recommended by the Japanese Horticultural Experiment Station. Selenium forms used were inorganic SeO₂ (here in after referred to Se) and organic selenium chelated with sugar fatty acid ester (here in after referred to chelated-Se). 10 ppm selenium solutions were treated to tomato plants with foliar applications, drenching, and foliar application plus drenching. Growth characteristics in terms of plant height, number of leaves, leaf area and chlorophyll content were significantly increased in the plot of foliar application of Se, and in the plot of foliar application plus drenching of chelated-Se than other plots, respectively. Transported contents of selenium into the tomato fruits were highest as 0.302 ppm in the plot of foliar application plus drenching of chelated-Se. Also, it had tended to be higher in the plot of foliar application plus drenching than in the plots of foliar application or drenching in both of Se and chelated-Se. Foliar application and drenching of organic chelated-Se were effective to produce the functional tomato fruits.

비만을 동반한 위암 환자에서 두 병을 같이 수술 치료한 경험(증례)

최경현,윤기영,문형환,신연명,서경원,안수미,송윤미,석정희,정경연,이은하 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.3

Obesity is growing problem in Korea. We had a case of bariatric surgery during gastric cancer operation. Patient was 29 year old Korean lady with early gastric cancer located in the lesser curvature side of the middle 1/3 of the stomach. Her body weight was 89 kg, height 163 cm, and thus body mass index was 33.5 kg/m2. Preoperative blood pressure was 130/90 mmHg, hemoglobin 12.9 g/dL, total lymphocyte count 3,280/mL, serum albumin 4.3 g/dL, CEA 1.1 ng/mL, CA 19-9 9.1 ng/mL, and alpha fetoprotein 2 ng/mL. Another associated disease was right thyroid follicular neoplasm. The chest X-ray was normal. After IM injection of 2,500 units of heparin 30 minutes before the induction of general anesthesia, she received curative subtotal gastrectomy and Roux en Y gastrojejunostomy when a malabsorption loop of 120 cm jejunum was incorporated between the Treitz ligament and the end to side jejuno-jejunostmy site at May 29th 2006. Her postoperative course was uneventful except a minor wound seroma and the elevations of serum amylase(up to 4 folds) and lipase(up to 2 folds). She lost her body weight 9 kg in 5th, 21 kg in 7th, and 27 kg in 10th postoperative months to became 61.5 kg. On follow up exams in July 2008, she gained 4 kg to overcome her weakness and fatigue. From the above result, the incorporation of a malabsorption loop during reconstruction phase of gastric cancer operation was a good option for obese gastric cancer patients especially in cases of early gastric cancer.

위 전절제술 후 발생한 근위부 비장동맥 가성동맥류 1례

서경원,신연명 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.2

Splenic pseudoaneurysm following upper abdominal surgery is uncommon but highly lethal complication. Surgical and angiographic interventions are used in treatment; however, optimal therapy remains unclear. We report herein the case of a 37-year-old woman in whom proximal splenic artery pseudoaneurysm ruptured into the small intestine via a fistula, following total gastrectomy. It causes massive bleeding, which was successfully managed by trans-catheter arterial embolization.

폐광산 주변의 목본 식생 현황 및 오염 토양에 대한 목본 종자의 발아 특성

서경원,손요환,김래현,구진우,노남진,경지현,김정규 한국환경농학회 2006 한국환경농학회지 Vol.25 No.1

10년의 차이를 가지는 두 시기에서 외과적으로 치료된 조기위암환자들의 임상병리학적 인자들의 변화경향

서경원,윤기영 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2

Backdround: Recently, frequency of early gastric cancer (EGC) is increasing owing to frequent attempt of endoscopy and its developing diagnostic technique. The aim of this study was that how characteristics of EGC change during 10 years to compare several clinicopathological factors. Methods: We studied retrospectively 298 and 255 patients with early gastric cancer who were treated open gastrectomy between January 1984 and December 1992(Early period, EP) and between January 1997 and June 2001(Late period, LP), respectively. We investigated clinicopathologic characteristics of age, gender, location of gastric cancer, size and depth of tumor, differentiation. Results: The ratio of male and female were 187 cases:111 cases(62.8%:37.2%)at EP and 177 cases:78 cases(69.4%:30.6%) at LP, mean age was 52.4years(25-80) at EP , 54.5years(20-77) at LP. Lymph node metastasis of 30 cases at EP(10.0%) and 29 cases at LP(11.4%) were found. The ratio of mucosal cancer and submucosal cancer is 56.7% : 43.3% at EP and 45.1% : 54.9% at LP.(p=0.008) Tumor size above 2cm and below 2cm were 34.2% and 65.8% at EP, 57.6% and 42.4% at LP.(p=0.000) In terms of differentiation according to WHO classification, the change of their ratio were not significant. Conclusion: We treated more cases of mucosal cancer and larger tumor at late period. It is concluded that this trend is owing to introduction of limited surgery. Future studies will be required to establish the treatment strategy of early gastric cancer.

간경변 환자에서 Oro-cecal Transit Time의 측정

원경준,이준,변유미,조민근,조주연,서정균,김영대,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.2

Background: Neurotransmitter like substances in the gut have been proposed to contribute to the overall portal systemic encephalopathy (PSE). The source of the ammonia in patients with PSE is mainly the small bowel, as a result of the conversion of glutamine in the diet to glutamate and ammonia. PSE is highly responsive to changes in diet, to antibiotic therapy and to ingestion of nondigestible disaccharides such as lactulose. This study was performed to evaluate the relationship between PSE and oro-cecal transit time. In addition, performed to evaluate the effect of severity, cause, complications of liver cirrhosis on oro-cecal transit time. Methods: Between August 2006 and February 2007, 48 cirrhotic patients consecutively was enrolled in study their oro-cecal transit time after informed consent was obtained. A non-invasive hydrogen breath test was used to study oro-cecal transit time (OCTT). Result: The OCTT were delayed in cirrhotic patients with PSE compared without PSE (123.3 ± 42.7 min vs 170.0 ± 58.3 min, p<0.05). OCTT tended to prolongate further as the damage in the liver got worse, nevertheless the result was statistically meaningless (p<0.111). Neither presence of ascites or cause of PSE had any influence on gastrointestinal transit. Conclusions: Cirrhotic patients with PSE have more delayed OCTT than without PSE. Further research is needed to find out the relationship between OCTT and severity of liver cirrhosis.

장간막정맥혈전증 1예

서경원,이상호 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.2

Mesenteric venous thrombosis is a rare disease accounting for 5-15%. MVT is generally difficult to diagnose and can be fatal because of delayed diagnosis and treatment. A case of extensive thrombosis of the mesenteric vein was diagnosed early and successfully treated in a 70-year-old female who was admitted to hospital because of bloody diarrhea and abdominal pain. Computed tomography(CT) showed remarkable thickening of the bowel walls and extensive thrombosis of superior mesenteric vein. Because intestinal infarction and peritonitis was seen, emergency operation was done and catheter-directed thrombectomy through mesenteric vein was successfully performed. She discharged without any complications.

측두엽 간질의 선택적인 후대뇌동맥 Sodium Amytal 검사 2예

이경열,김옥준,서범천,이병인,김원주 대한신경과학회 1999 대한신경과학회지 Vol.17 No.1

퇴행성 슬관절염 환자의 증상 중증도 지표와 DITI의 상관성 연구

서병관,류성룡,강중원,안경애,이재동,최도영,김건식,이두익,이윤호,이상훈 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives : To investigate the applicability of thermography as severity measurement in the patients with osteoarthritis (OA) of the knee. Methods : Data were obtained from 80 patiens with OA of the knee. They were asked to answer two disease-specific questionnaire (Western Ontario and McMaster Universities (WOMAC) OA index, Lequesne's Functional Index (LFI)), one generic instrument (Korean Health Assessment Questionnaire (KHAQ)), VAS in order to assess the severity of disease, quality of life, degree of pain and taken thermography in standardized environment. Results : The thermal difference between ipsilateral side and contralaterla side of lateral aspect of knee was correlated with that of medial aspect of knee, and the thermal difference of anterior thigh was correlated with that of lateral, medial aspect of knee and patella region. Age, duration of disease, duration of morning stiffness, sex, crepitus, and painful side of knee were not correlated with the thermal differences of each region. LFI, WOMAC, WOMAC pain subscale, WOMAC stiffness subscale, WOMAC physical function, KHAQ,, VAS were not correlated with the thermal differences of each region. Conclusion : Further study on the thermography on OA of the knee in population with appropriate severity grade and the standardization of analysis of thermographic data were recommended.

혈중 아연농도와 위암환자의 임상 병리학적 상관성

서경원,윤기영 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

Objective: Until it was recently overtaken by stomach cancer was the most common cancer in the world. It is still a major cause of death in many countries. Previous most presentation is a discussion of the possible role of micronutrients in the etiology of common human cancers. The aim of this study is to explore the relationship between the Zinc trace elements and clinicopathologic nature in gastric carcinoma. Methods: Trace element Zn were measured in primary gastric carcinoma from 189 patients. It was compared with age, cancer stage, cancer location and pathological types with the contents of Zn. Results: There were no significant differences in the contents of Zn among primary gastric tumors, age (P=0.207 post hoc test), and no significant differences in the contents of Zn between gastric cancer stage (P=0.688 post hoc test). There were no significant differences in the contents of Zn among primary gastric tumors, location (P=0.99 post hoc test), and no significant differences in the contents of Zn between gastric cancer WHO pathological type (P=0.553 post hoc test). Conclusions: There were no significant differences in the contents of Zn among primary gastric tumors, age, cancer stage, cancer location and WHO pathological type.