TLD 방사선 센서용 판독장치의 제작

우홍,강희동,최희동,이상윤,도시홍,김도성 경북대학교 센서기술연구소 1992 센서技術學術大會論文集 Vol.3 No.1

상완골 과 상부 골절에서의 이중 긴장 대 기법을 이용한 수술적 치료

강호정,김홍희,심동준,한수봉,강응식 대한골절학회 2002 대한골절학회지 Vol.15 No.4

목 적 : 이중 긴장 대 기법을 이용한 상완골 과 상부 골절의 임상적 결과를 분석하여 그 유용성을 보고하고자 한다. 대상 및 방법 : 1992년 10월부터 2001년 9월까지 상완골 원 위부 골절로 치료한 환자 중 이중 긴장 대 기법을 시행한 14예를 대상으로 하였다. 골절의 원인으로서는 실족에 의한 단순 손상이 11예, 교통사고에 의한 손상이 2예, 직접 타격에 의한 손상이 1예가 있었다. AO/ASIF 분류 방법에 따라 분류하면 A2가 2예, A3이 1예,. C1이 6예, C2가 3예, C3이 2예였으며, 성별로는 남자가 5예, 여자가 9예였고, 평균 나이는 51.6 세 (최소 15세, 최대 88세)였다. 분쇄 골절이 심한 4예에서 주두 절골 술을 시행하였다. 술 후 고정기간은 평균 20.6일 이었고, 경화를 보인 시기는 술 후 평균 10.1주 였다. 65세 이상의 5예에 있어서는 술 전에 골 밀도 검사를 시행하였으며, 대퇴경부의 평균 T-score가 -3.65였고 요추부의 평균 T-score가 -2.97이였다. 평균 추 시 기간은 평균 16.4개월(최소 12개월, 최대 29개월) 이였다. 평가는 최종 외래 내원시 주관절의 운동 범위, 통증 유무, 환자의 만족도를 조사하였다. 결 과 : 최종 추후 결과를 분석하였으며, 운동범위는 Excellent군이 8예, Good군이 4예, Fair군이 2예 였으며, Poor군은 없었다. 10예에서는 술 후 통증이 전혀 없었으며, 4예에서는 가끔씩 통증을 호소하였다. 합병증으로는 1예에서 주두에 K-강선 삽입부위의 피부자극에 의한 통증으로 술 후 6개월째 조기 제거를 시행하였다. 척골신경 전방 전위 술을 8예에서 시행 하였으며, 시행하지 않은 6예 중에 2예에서 척골신경 자극증상이 있었다. 그 중 1예에서는 술 후 8개월째 척골신경 전방 전위 술을 시행 받았으나, 다른 1예에서는 대중적 치료로 증세가 호전되었다. 1예에서 K-강선 삽입부위에 부분적 피부괴사 소견이 보였으나 핀 제거 술 및 창상 치료 후 치유되었다. 결 론 : 이중 긴장 대 기법을 이용한 상완골 과 상부 골절의 치료가 수술이 간단하고 수술 시간을 단축시킬 수 있으며, 정복 시 골막의 박리 손상을 줄일 수 있어 골편의 탈활(devitalization)이 적으며, 골절부의 압축력을 얻을 수 있다. 특히 젊은 환자의 단순 과 상부 골절에서 과도한 술기를 피하고 조기 관절 운동을 하기위한 경우나, 술 전 골 밀도 검사상 골 다공 증을 동반한 분쇄가 심한 노령 환자의 과상부 및 과간 골절의 치료에 있어 이중 긴장 대 기법은 상완골 상부 골절의 치료에 유용한 방법이 될 수 있으리라 사료된다. PURPOSE : This study evaluated the clinical result of supracondylar fractures of the humans treated with double tension band osteosynthesis. MATERIALS AND METHODS : From October 1992 to September 2001, 14 patients with supracondylar fractures of the humerus were treated by method of double tension band osteosynthesis. eleven fractures were the results of slipped down injury and two traffic accidents and one direct trauma. All fractures were classified according to the AO fracture classification (A2; 2. A3; 1. C1; 6, C2; 3. C3; 2). There were 6 males and 9 females with average age of 51.6 age of 51.6 years (range 15 to 88). Olecranon osteotomy was performed in 4 patients with severe comminuted fractures. Postoperative immobiliza-tions were required for an average of 20.6 days and consolidations were noted after an average of 10.1 weeks. Before operation, bone marrow density studies were performed in five fractures above 65 years. Average T-score of the patients were -3.65 on femur neck and -2.97 on lumbar spine. All patients were re-examined after an average of 16.4 months. RESULTS : Union and consolidation was achieved in all 14 patients judged their results as excellent and four as good. Ten patients had no pain and four had only occasional discomfort. Early removal of K-wires was performed in one patient because irritation of one side K-wires were develop. Sensory change of the ulnar nerve was noted in two patients. Anterior transposition of ulnar nerve was performed in one patient and the other was improved spontaneously. Skin necrosis was developed in one patient but was healed after pin removal and conservative care. CONCLUSION : The advantages of double tension band wiring are an easier and faster procedure, less periosteal and muscle damage, and more symmetrical compression than double plating. Therefore, in the commiuted osteoporotic fracture with poor tolerance for internal fixation with the plate or the simple supracondylar fractures in young age, double tension band osteosynthesis can provide sufficient and secure stability to allow early functional exercise.

Polystyrene 입자 수용액에서 프랙탈 차원에 관한 광산란 실험 연구

강명화,김두철,강창희,현동걸 제주대학교 1994 논문집 Vol.39 No.-

Using light scattering technique, we measured intensities of scattered light from aggregation of polystyrene particles of 114nm in a solution of NaCl in the concentration from 0.15 to 2mol/ℓIntensity data give direct information that aggregated cluster are built with fractal structure ; We find that the value for fractal dimension of aggregation in the fast regime 1.25≤c≤2mol/ℓis 1.55 ±0.05 that is nearly consistent with diffusion-limited-aggregation model, whereas in the slow regime (0.3≤c≤0.5mol/ℓ)the value of fractal dimension is 2.12±0.05 agreed with reaction-limited-aggregation model.

전신 마취중 발생한 악성 고열증 1례

강봉진,김동희 단국대학교 1998 論文集 Vol.32 No.-

Malignant hyperthermia is a potentially fatal hypermetabolic syndrome characterized by hyper-pyrexia and skeletal muscle rigidity. It can be induced by all of the currently used anesthetics or by injection of succinylcholine. We experienced one case of malignant hyperthermia during tympanomastoidectomy under O_2-N_2O-enflurane anesthesia with induction by pentothal sodium and succinylcholine. At two and half hours after induction, tachycardia, generalized muscle rigidity, cyanosis of the extremities and skin mottling appeared. Body temperature was high as much as 42℃ and blood pressure was dropped to 50/38/32 mmHg. Anesthesia was terminated. Dantrolene, a specific drug for malignant hyperthermia, was not available immediately. So vigorous treatments to reduce the body temperature-external ice packs and iced saline massage, cold intravenous saline, gatric and urinary bladder lavage, intraperitoneal lavage-were attempted. After these vigorous treaments, the body temperature was lowered to 37℃ and vital signs were restored to normal ranges. We report a malignant hyperthermia case with review of clinical features and emergency treamens.

한국인 지원자에서 니모디핀의 생체이용율연구

강원호,심희옥,남진경,김동출 忠南大學校 生命科學硏究院 醫藥品開發硏究所 2006 藥學論文集 Vol.21 No.-

A reversed phase HPLC method was developed and validated for the determination of nimodipine in human plasma. Nitrendipine was used as an internal standard. Calibration curves were linear in the concentration range of 5~300 ng/ml. The coefficient of variation of the intra- and inter-day precision was below 15%. The coefficient of variation of the accuracy was below 15% in the concentration range investigated. A bioavailability study was performed using the validated HPLC method. Eight healthy male volunteers were orally administered 30 mg of nimodipine. The pharmacokinetic parameters were calculated using WinNonlin. The mean values of AUC_(24hr) was 64.0±31.3 ng·hr/ml, C_(max) was 46.5±31.2 ng/ml, T_(max) was 0.54±0.17 hr and t_(1/2) was 3.03±2.26 hr. The pharmacokinetic parameters and the HPLC method can be used for the design of bioequivalence study of nimodipine.

레이저 박피술의 피부면적 감소효과와 레이저 punch out 병변의 치유에 대한 실험적 연구

강동희,윤을식,구상환,안덕선,박승하 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3

An experimental study was designed to analyze the surface reduction effect of ultrapulse carbon dioxide laser on the skin of guinea pigs receiving laser resurfacing. Two squares of skin measuring 3x3 ㎠ were designed on each side of the abdomen of guinea pigs(n=10). Five animals received laser resurfacing on their abdomen at energy of 250mJ/5 watt, and five other animals received 500 mJ/5 watt. On each animal, the left side square was treated with one pass of a CO2 laser, and the right side q=square was treated with two passes using a C.P.G. scanner. The size of the resurfacing area was determined by celluloid overlays at 1,2,3,4 and 6 weeks. Immediately following laser resurfacing, the area was decreased to 69%(left side) and 56%(right side) of the designed area in the 250 mJ/5 watt group, and 59% and 40% in the 500mJ/5 watt group. After 6 weeks, the resurfaced area had been reduced to 70% and 56% of the designed area in the 250mJ/5 watt group, and 60% and 40% in the 500mJ/5 watt group. As a result, the effect of surface reduction by CO2 laser resurfacing increased at a higher power and when more passes of the ultrapulse carbon dioxide laser were applied. The laser treated skin continued to maintain its contracted dimensions. These findings suggest that ultrapulse carbon dioxide laser may be an effective treatment method for rhytides. Another experiment was performed on multiple punch-out lesions on guinea pig skin(n=2) with 1,2,3 mm collimated hand pieces for the purpose of determining a new laser treatment method. After 4 weeks, on gross and histological examination, there were no differences in the healing of multiple punch-out lesions and the healing of punch-out lesions was complete without any scarring. These findings suggest that the laser punch-out method can be used for the treatment of acne scars.

Pd(O)-촉매를 이용한 알릴 고리 카보네이트의 제거 및 분자간 축합반응 연구

강석구,박동철,박찬희,홍륭기 성균관대학교 기초과학연구소 1995 論文集 Vol.46 No.1

The alkyl substituted allylic cyclic carbonates 1a-d undergo elimination by using a catalytic amount of Pd(0) complex to form dienols 2 a-b. However, on treatment of the unsubstituted or phenyl substituted allylic cyclic carbonates 1e and 1f with Palladium(0) catalyst, deprotonation-elimination of π-allyl Palladium complex followed by condensation with the other π-allyl Palladium complex provided the coupled products 3a and 3b, respectively.

油脂가 高Cholesterol 食餌 흰쥐의 血淸 및 肝臟脂質成分에 미치는 影響 : Ⅰ. 數種油脂의 混合攝取效果 Ⅰ. Effect of dietary mixing fat and oils

姜東姬,禹永淑 진주여자전문대학 1987 論文集 Vol.9 No.-

Hyper cholesterolemic male rats of Wistar, divided into seven groups, were fed for 3 weeks with the diets contanning several different fat and oils The concentration of the lipid peroxide, T-cholesterol, phospholipid and triglyceride in the serum and liver were measured along with the HDL-cholesterol concentration of the serum. The results were as fallows : 1. The concentration of T-cholestrol in the serum showed the lowest in the group 2 of 5 % lard + 4.25 % perilla oil + 0.75 % soybean oil and in the group 6 of 5 % lard + 3.5 % perilla oil + 1.5 % sardine oil. The concentration of HDL-cholesterol in the serum increased slightly in the group 1 of 10% lard and in the group 6, of 5 % lard + 3.5 % perilla oil + 1.5 % sardine oil. The concentration of HDL-cholesterol against the T-cholesterol concentration was also higher group 6 than any other groups. 2. The concentration of PL in the serum showed the lowest in the group 4 of 5% lard + 2.5 % perilla oil + 2.5 % soybean oil, The concentration of TG in the serum decreased in the group 2 and 3, 5, but it increased considerably in the group 1. 3. The concentration of T-cholesterol in the liver, all groups were lower than in the control group and those of the group 3 decreased remarkerbly among all the groups. 4. The concentration of PL in the liver was not significantly different amorg all the groups and the concentration of TG in the liver showed the lowest in the group 5. 5. The concentration of LPO in the serum and liver, all groups were much higher than in the control group. The concentration of LPO in the serum decreased in the group 2 and the concentration of LPO in the liver decreased considerably in the group 4 among all the groups.

健脾益氣法의 腫瘍治療活用에 對한 硏究

姜硏伊,金聖勳,金東熙 대전대학교 한의학연구소 2002 한의학연구소 논문집 Vol.10 No.2

In review of "inviorating spleen an supplementing qi" of clinical and experimental studies on malignant tumor, we obtained the conclusions as follows 1. Asthenic splenic qi is an important factor in mutation, occurrence and development of tumor. 2. The anti-tumor mechanism of "invigorating spleen and supplementing qi" is improvement of immune suveillance, cntroling cell proliferating period and enhancing body metabolism. 3. "Invigorating spleen and supplementing qi" is often used with " nourishing kidney" or "expelling pathogen" for treating cnacer. 4. In experimental studies, "invigorating spleen and supplementing qi" has effects on inhibiting occurrence and development of tumor, protecting mutation, inhibiting recurrence and metastasis, immune activity, enhancing metabolism, promoting bone marrow hemopoietic cell proliferation, increasing anti-tumor effect and protecting normal cells. 5. In clinical studies, "invigorating spleen and supplementing qi" has effects on prolonging the survival period of cancer patients, improving clinical symptoms and quality of life of cancer patients, degrading the side effects of western therapie(operation, chemotherapy and radiotherapy). 6. "Invigorating spleen and supplementing qi" is an extensive discipline of syndrome differentiation used to inhibit occurence, development, recurrence and metastasis.

중공유리구에 고정화된 광촉매를 이용한 남조류의 증식억제

강민수,정익상,우승희,김성우,이동근 경상대학교 환경보전연구소 2001 環境保全硏究所報 Vol.9 No.-

Photocatalytic inactivation of Microcystisaeruginosa was carried out with the TiO₂-coated pyrex hollow glass beads under the illumination of UV light(370㎚ wavelength). After being irradiated with UV light in the presence of the TiO₂-coated pyrex glass beads, Microcystis aeruginosa, known as typical cyanobacteria, lost their photosynthetic activity, and the colonies of Microcystis cells were completely separated into individual spherical one. Complete photocatalytic inactivation of Microcystis aeruginosa was obtained in about 30min. Photosynthesis activity of the cyanobacteria could be inhibited effectively after being reacted photocatalytically with TiO₂ immobilized hollow glass ball.