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      • 메토클로프라마이드의 생체이용율시험

        심희옥,한수정,김동출 충남대학교 약학대학 의약품개발연구소 2003 藥學論文集 Vol.18 No.-

        A reversed phase HPLC method with detection 273nm was developed and validated for the determination of metoclopramide in human plasma. Timolol was used as an internal standard. Calibration curves were linear in the concentration range of 10~120 ng/㎖. The coefficient of variation of the intra- and inter-day precision was below 15%. The coefficient of variation of the accuracy was below 15% in the concentration range investigated. A bioavailability study was performed using the validated HPLC method Eight healthy human male volunteers were orally administered 20 mg of metoclopramide. The pharmacokinetic parameters were calculated using WinNonlin. The mean values of AUC_(LAST) was 340.3 ng . min/㎖, C_(max) was 74.3 ng/㎖. T_(max) was 1.0 hr, t_(1/2) was 7.6 hr. The pharmacokinetic parameters and the HPLC method can be used for the design of bioequivalence study of metoprolol.

      • KCI등재

        노인일자리사업 참여지속의지가 생활만족도에 미치는 영향 - 사회적 자본의 매개효과 -

        심희옥,남지승 사단법인 인문사회과학기술융합학회 2019 예술인문사회융합멀티미디어논문지 Vol.9 No.11

        The purpose of this study was to identify the influence of the persistence of participation in the Senior Employment Program on the quality of life and to improve the quality of life of the elderly by verifying the mediating effect of social capital. The survey was the data of 275 participants in the Senior Employment Program in P city, Gyeongsangbuk-do were analyzed. The main results of this study are as follows. First, persistence of participation in the Senior Employment Program has a statistically significant effect on quality of life, Second, persistence of participation in the Senior Employment Program has a statistically significant effect on social capital. Third, as a result of the research model, it was found that persistence of participation in the Senior Employment Program has a statistically significant effect on quality of life and then the mediator, social capital, was found to have a full mediating effect. Based on the results, this study aims to provide practical and policy implications for social welfare to improve the quality of life of senior workers. 본 연구의 목적은 노인일자리사업 참여지속의지가 생활만족도에 미치는 영향을 파악하고, 사회적 자본의 매개효과를 검증함으로써 노인의 생활만족도를 향상시키고자 하였다. 조사는 경상북도 P시의 노인일자리사업 참여자 275명의 자료를 분석하였다. 본 연구의 주요 결과는 다음과 같다. 우선, 노인일자리사업 참여지속의지가 생활만족도에 정적(positive)으로 유의한 영향을 미치는 것으로 나타나 참여지속의지가 높아질수록 생활만족도가 높아지는 것을 확인할 수 있었다. 둘째, 노인일자리사업 참여지속의지는 사회적 자본에 정적(positive)으로 유의한 영향을 미치는 것으로 나타나 참여지속의지가 높아질수록 사회적자본이 높아지는 것을 확인할 수 있었다. 셋째, 노인일자리사업 참여지속의지는 생활만족도에 정적으로 유의한 영향을 미치며, 이 관계에서 매개변인인 사회적 자본은 부분매개효과가 있는 것으로 확인되었다. 이와 같은 연구결과를 기반으로 노인일자리사업 참여자의 생활만족도를 증진시키기 위한 사회복지 실천적ㆍ정책적 방안을 모색하고자 한다.

      • KCI등재

        아동의 모래상자에 나타난 십자가의 상징적 의미에 대한 연구

        심희옥 한국아동심리치료학회 2023 한국아동심리치료학회지 Vol.18 No.1

        This study examines the symbolic meanings of the cross in children’s cases of sandplay therapy with the consideration of a myth and the meanings of before and after Christianity. For this, when and how the cross appears, what meanings of the cross exist, and how therapy is processed with the cross, are explored. The cross exists from prehistoric times and means life energy, life power, eternal life, and change through initiation. As a myth, the cross means sacrifice, death, rebirth, and wisdom. In pre-Christian times, the cross means unification, synthesis, harmony, victory, life, fullness, and integrity. In Christian times, the cross means redemption through death, hope, victory, and resurrection. The cross can appear in any phase during therapy by making the cross with sand or using cross figures. In terms of the symbolic meanings of the cross, four children seem to gain spiritual energy for encouragement and guidance, the expression of despair by burying the cross, which means hope, seeking balance in internal world, and praying for redemption similar to meanings in a myth and before and after Christianity. The cross appearing in sandboxes seems to be very functional and meaningful through the process of therapy. Practical issues in sandplay therapy are suggested.

      • KCI등재후보

        수동형 공격행동 문제를 보이는 저소득 가정 남아의모래놀이치료 사례연구

        심희옥 한국아동심리치료학회 2013 한국아동심리치료학회지 Vol.8 No.2

        The study showed a sandplay therapy case for a 5th grade boy having passive aggression problems, such as arson, disobedience to authority etc. His parents showed inappropriate parenting, such as neglect and severe physical punishment. The goal of the therapy was to make the client express the lack of needs satisfaction under the free and protected space to recover his impaired ego. There were 69 sessions. In the initial parts of therapy(1-6, the expression of his parents and situations), the client showed his poor situations in the first sandtray by putting a boat poked by a shovel. This scene displayed the image of his negative father who prevented his mother's movement. In the second session, the client showed neglect he experienced by putting a baby in a bed alone and helplessness of a disable girl in a wheelchair who seemed to represent him. In the intermediate sessions(7-64, the struggling with war, fire, capital punishment play, car accident), he repeated wars, fire plays, capital punishments and car accidents with hospital playing, constructing, cooking and physical training. In the final parts(65-69, the rescuing people from disaster and fire), he showed “Rescue Forces” which suppressed disasters and saved people. This study showed the effectiveness of sandplay therapy since the client was freed from passive aggression problems.

      • KCI등재후보

        내재화 및 외현화 행동문제를 보이는 조손가정 남아의 모래놀이치료 사례연구

        심희옥 한국아동심리치료학회 2012 한국아동심리치료학회지 Vol.7 No.2

        This study explored the effects of sandplay therapy of the 5th grade boy in an elementary school according to the viewpoints of sandplay literatures and analytical psychology. He showed severe internal and external behavioral problems according to K-CBCL from his class teacher. The goal of the therapy was to lessen his severe behavioral problems under the free and protected space in the sandplay therapy. There were 42 sessions of sandplay therapy. The client showed his situations in the first parts of therapy(treasure, keeping precious things) by putting a treasure which was surrounded by keepers in the middle of the sandtray. In the middle sessions(blessing himself and holding the ceremony of magic squares), he repeated making birthday cakes in order to bless himself and holding the ceremony of magic squares with candles for transformation through numinosum. In the final parts(harmonization and obtaining the treasure), he showed harmonization with his situations and obtained the treasure he has sought for. This study shows the effectiveness of sandplay therapy since his severe behavioral problems were lessened.

      • KCI등재후보

        정서조절이 힘든 초등학생의 모래놀이치료 사례

        심희옥 한국아동심리재활학회 2007 놀이치료연구 Vol.11 No.3

        내담자는 모래상자에서 본인의 모성갈망을 표현하고 이것의 양육을 반복하였다. 이런 양육으로 내적인 성장이 이루어져 구강기 고착이 풀리는 경험을 하였다. 장애 형과의 동일시에서 자신도 형만큼 돌봄이 필요하다거나 깊은 장애를 앓는 형과 자신도 같은 존재임을 표현하기도 하였다. 양육으로 내적인 성장을 하여 구강기 고착이 풀리고 변화되었는데 다시 모의 뱃속까지 그리고 3, 4세로 퇴행을 하고 투쟁을 하며 낚시를 통해 힘이 생기고 성장하여 모와의 심리적인 독립이 가능해지는 경험을 하였다. 이어 자아가 구축되는 성장을 위한 연결을 준비하고 다시 투쟁을 반복하며 드디어 자기를 확고히 구축하여 내담자의 가족에 대한 에너지가 흘러 가족과 통합되어 자기조절이 가능해지면서 불안을 떨치고 안정을 찾아 심리적인 외상이 치유되는 내면의 작업을 마쳤다. This study showed a case of sandplay therapy for a 1st grade boy who had a severely handicapped older brother having thorough treatments from the client's birth. Because of the unusual caring for the brother, the client had a difficulty of having appropriate parenting. The mother expected the client to behave more maturely with severe discipline for his immature behaviors. The client showed emotional difficulty, such as withdrawal, talkativeness, separation anxiety etc. There were 34 sandtrays of animals, monkeys, people, unconscious and conscious repeatedly shown. The client was in oral fixation state and fed his repression and fixation during the early sessions of the therapy. He appeared very comfortable without talking verbally in this therapy since he said many things through his sandtrays. He revisited the period when he was emotionally deprived and repeated struggles and achieved and became emotionally independent from his mother. Finally he finished his internal works with establishing strong ego development by showing a train running and peaceful and flowery scenery.

      • KCI등재후보

        생모와 이별한 5세 남아의 모래놀이치료를 통한 의식의 탄생과 분화

        심희옥 한국아동심리재활학회 2008 놀이치료연구 Vol.12 No.3

        본 연구는 어린 연령에 헤아리기 힘든 생모와의 이별을 경험한 만 5세 남아에 대한 모래놀이치료 사례이다. 내담자는 생모로부터 신체적이고 정서적인 학대를 받기도 했고 이혼 후 조모에게 맡겨졌을 때 감정의 기복이 심했고 버려질 것에 대한 두려움이 컸으며, 부에게 부정적인 정서가 있었다. 본 사례는 총 35회기의 모래놀이치료로 이루어졌다. 모래상자에 홍수, 자연재해, 화산폭발의 주제가 많아 본 사례를 의식의 탄생을 위한 홍수신화에 적용해 탐색하였다. 내담자는 자신과 가족의 처지를 끊어진 철도 표현을 시작으로 자신의 혼란을 드러냈다. 또한 내담자는 모래상자에 담긴 모래가 자신인 차를 못 가게 방해하는 것으로 표현하였다. 치료 중반쯤 내담자는 모를 마음에서 떠나보냈다. 반복적으로 자신의 처지를 홍수로 표현하기도 하며 모래를 다 치우고 싶어 하였다. 내담자는 혼란과 상처를 가져다 준 생모이기도 한 모래의 치유능력으로 점점 정돈되고 정화되어 갔다. 내담자는 모래놀이치료 후반에 차들을 깨끗이 씻는 행위를 통하여 새로운 의식을 갖게 되는데 이는 단순한 정화가 아니라 새로운 창조를 이루어 모래 위에 길을 만들고 차를 달리게 하며 새로운 의식 세계를 펼쳤고 모와 분화되어 갔다. This study showed a case of sandplay therapy of a 5 years old boy who had to separate from his own mother. Forgetting his own mother is inscrutable for the little boy. The client had experiences of physical and emotional abuse from his mother. When the client came to his grandmother after divorce, he was emotionally unstable and had a fear of abandonment and negative feelings toward his father. There were 35 sandtrays. The client expressed his inner confusion by putting the half of railroad in his first sandtray. Since in the early parts of his sandplay, flood, natural disaster and volcanic eruption appeared, the myth of flood for the birth of consciousness was applied to examine the process of sandtrays. He expressed that sand prevented cars which were himself from running and that he wanted to get rid of the whole sand in the sandbox. In the middle of sandplay therapy he let his mother go from his mind. His mind was becoming clean by washing away his disorder and wounds by water and sand. Through purification new consciousness appeared. In sandtrays roads were made for running cars. He also achieved differentiation from his mother owing to the self-healing of the unconscious.

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