우심방을 침범한 거대 비호지킨씨 림프종 1예

강상범,진승원,이은경,박용현,최용호,김용주,박준철,김재형,홍순조,최규보,권종범,원용순,박건,이은희 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

급성하벽심근경색에서 전흉부유도 ST절 하강의 의의

정병천,배호상,곽동훈,김영태,배용학,황종현,임현주,류재근,조용근,채성철,전재은,박의현 慶北大學校 醫科大學 1997 慶北醫大誌 Vol.38 No.2

목적 : 급성하벽심근경색증 환자에서 심전도상 흔히 동반되는 전흉부유도 ST절 하강의 의의를 알아보았다. 방법 : 심근경색후 24시간에서 48시간에 얻은 심전도를 기준으로 52명의 급성하벽심근경색증 환자를 전흉부유도에서 ST절의 하강이 있는 군과 없는 군으로 나누었으며 심도자, 관상동맥조영술, 심초음파도 및 방사성 핵종을 이용한 좌심구혈율 측정 등을 시행하였다. 결과 : 1) 좌심실확장기말압은 전흉부유도에서 ST절의 하강이 있는 경우에서 16.9±5.33mmHg로 없는 경우의 11.0±4.02mmHg보다 유의하게 높았다(p<0.05). 그러나 운동량 및 좌심구혈을은 흥부 유도상 ST절의 하강이 있는 경우 7.6±3.0 METs 및 53.9±9.1%로 없는 경우의 9.1±2.7 METs 및 54.6±9.5%보다 낮았으나 통계적 유의성은 없었다(p=0.180, p=0.823). 2) 관상동맥조영술상 전흉부 ST절의 하강이 동반된 군에서는 유의한 좌전하행지나 좌회선지의 협착이 있는 경우가 60.9% 및 57.9%로 ST절의 하강이 없는 군에서의 34.5% 및 7.7%와 비교해 좌관상동맥에 협착이 동반된 경우가 많았다(p=0.050, p=0.001). 3) 관상동맥조영술상 세 혈관질환의 빈도는 흉부유도상 ST절의 하강을 보인 23예에서 10예로 ST절 하강이 없었던 29예중 2예에 비하여 유의하게 많았고(P=0.007), 단 혈관질환의 빈도는 ST절의 하강을 보인 군에서 23예중 5예로 ST절 하강이 없었던 29예중 17예에 비하여 유의하게 적었다(P=0.002). 두 혈관질환의 경우에는 각각 8예와 10예로 양군간에 유의한 차이가 없었다. 4) 흉부유도상 ST절 하강의 빈도는 단 혈관질환 22예 중 5예에서, 두 혈관질환 18예중 8예, 세 혈관질환 12예 중 10예에서 관찰되어 협착이 있는 관상동맥의 수가 많을수록 ST절의 하강이 나타나는 빈도가 많음을 보였다(p=0.00308). 그러나 흉부유도상 나타난 ST절의 하강을 모두 합하여 구한 ST절 하강의 합은 협착이 있는 관상동맥의 수와 통계적인 유의성이 없었다. 5) 심초음파도상 좌심실 하벽의 벽운동은 ST절 하강을 보인 군에서는 akinesia가 83.3%, hypokinesia가 11.1%, 정상 벽운동이 5.6%로, ST절 하강이 없었던 군에서의 dyskinesia가 3.6%, akinesia가 39.3%, hypokinesia가 25.0%, 정상 벽운동이 32.1%와 비교하여 ST절의 하강이 있는 군에서 유의하게 벽운동의 장애가 빈번함을 보였다(p=0.03891). 그러나 좌심실전벽, 측벽 및 중격부위에서는 유의한 벽운동의 차이가 없었다. 결론 : 급성하벽심근경색증 환자의 전흉부유도에서 ST절의 하강이 동반되는 경우 다혈관 질환의 가능성이 높으며 좌심실확장기말압이 상승되었고 운동능력은 감소되어 있었다. 또한 심초음파도상 좌심실하벽의 벽운동장애도 심하였다. 따라서 전흉부 ST절의 하강을 동반한 급성하벽심근경색증 환자는 전흉부유도에 ST절 하강이 없는 경우보다 예후가 불량할 것으로 생각되며, 보다 적극적인 치료가 필요할 것으로 생각된다. The purpose of this study was to determine the significance of precordial ST segment depression appearing during acute inferior myocardial infarction and to assess the correlation of that with angiographic finding. 52 patients were allocated into two groups based on the existence of precordial ST segment depression : 23 patients with ST segment depression and 29 patients without ST segment depression. The extent of coronary artery disease as well as the prevalence of significant stenosis (≥70%) in left anterior descending artery were more frequent in patients showing precordial ST segment depression than in patients not showing them (p=0.050) and the result were similar in cases of left circumplex artery (p=0.001). On echocrdiographic examination of left ventricular (LV) wall motion, it showed more severely decreased inferior LV wall motion in patients showing precordial ST segment depression than in patients not showing them (p=0.03891) even though the other segment of LV wall motion didn't show the statistical difference between both groups. The other cardiac parameters such as LVEDP, exercise amount (METs) and ejection fraction were tend to showing bad profile in patients with precordial ST segment depression. From the above results, we could deduce that patients with precordial ST segment depression have relatively large infarction or concomitant left coronary artery disease, so they need more caution and intensive theraphy.

헬륨 마이크로파 플라즈마 토치의 개발과 특성에 관한 연구

曺競鉉,朴勇男 한국교원대학교 환경과학연구소 2001 환경연구논문집 Vol.- No.6

MPT는 최근에 개발된 마이크로파 플라즈마로서 수용매에 강하다. 여러 가지의 변형된 형태의 MPT를 개발하여 구조에 따른 플라즈마의 방전되는 형태를 조사한 결과 이중관 토치는 플라즈마 기체를 적게 소모하여 쉽게 플라즈마가 형성되었으나 토치의 끝이 높은 온도에 견디지 못하고 쉽게 상했다. ICP토치와 같은 형태의 삼중관 토치에 석영관을 중심관으로 사용할 때 가장 안정되고 대칭적인 플라즈마를 형성할 수 있었다. 바탕선을 조사해 본 결과 He MPT는 대기 중으로 돌출되어 대기와 많이 혼합되고 질소에 의해 quenching되는 것으로 보여진다. Membrane desolvator를 탈용매화 장치로 사용하여 헬륨 MPT의 감도를 조사해 본 결과 아르곤 MPT와 비교할 때 대부분의 원소에 대헤 검출한계가 10배 이상 높았다. 그러나 여기 에너지가 높은 원소는 비교적 효율적으로 검출할 수 있었다. 헬륨 마이크로파 플라즈마는 적은 양의 플라즈마 기체만 필요하여(약 1.6L/min) 경제적이며 매우 안정된 형태를 보여주었다. 플라즈마의 분광특성을 조사한 결과 들뜸온도 4950 K, 전자 밀도 3.28×10^(14) cm^(-3)로 측정되었다. MPT, which bas been developed recently, is very tolerant to aqueous samples. Several types of MPT have been investigated and is found that the double concentric tube could sustain a stable plasma at a low plasma gas flow rate. However, the tip of torch is easily ruined. Triple concentric torch has shown the best stability and the plasma shape, much like that of ICP, especially when the central channel is quartz. The plasma is exposed and mixed with air as is suggested from the background spectrum, which leads to quenching of He MPT. Sensitivity of helium MPT equipped with a membrane desolvator has shown 10 times lower than that of Argon MPT for most of elements except for the ones with relatively high excitation energy. He MPT requires small plasma flow rate (about 1.6 L/min), stable and simple to use. Excitational temperature and electron number density measured are 4950 K and 3.28 × 10^(14) cm^(-3), respectively.

내시경적 절제로 진단된 폴립 형태의 심재성 낭종성 위염 2예

허종현,조영화,성용완,유재훈,구동영,김갑식,노지훈,문원 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

Gastritis cystica profunda (GCP) is a disease characterized by hyperplastic and significant extension of cystic dilatation of the gastric mucous glands, which results in a cystic lesion in gastric submucosa. It often occurs on the part of gastroenterostomy, but can be found in the stomach without any previous surgery. GCP has variable gross finding including solitary polyps, diffuse ones, submucosal tumors, and rare giant gastric mucosal fold. It is difficult to tell GCP from a cancerous lesion by gross finding that the disease demands a necessary tissue biopsy, though GCP is commonly showed as a benign in the progress. We report a case of GCP in polypoid types diagnosed by endoscopic polypectomy.

내시경역행성담췌관조영술 후 발생한 종격동기종, 피하공기증, 긴장성 기흉 1예

조용건,이현승,권균홍,김자영,김봉진,김지연,배용목,박선자 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

However, Endoscopic retrograde cholangiopancreatography (ERCP) is still helpful procedure for the diagonosis of the pancreatobiliary disease and treatment through endoscopic sphinterectomy (EST) is relatively safe, these have possiblity of complications such as hemorrhage, infection, panceatitis, and perforation. ERCP related perforation was rarely reported in 0.3 to 1.1% of previous study, but most serious complication. A report of Pneumomediastinum, Tension Pneumothorax complicating perforation after ERCP and EST is very uncommon. In our hospital, we experienced case of pneumomediastinum, subcutaneous emphysema, and tension pneumothorax after ERCP and EST, and the patient (a 58 years old female with suspicious common bile duct stone) was treated successfully with conservative treatment.

서울 남산 도시자연공원의 대기정화기능과 가치

조현길,조용현,안태원 江原大學校 附設 環境硏究所 2003 環境硏究 Vol.20 No.-

본 연구는 서울시 남산 도시자연공원을 대상으로 식생의 대기 CO₂SO₂및 NO₂흡수능을 계향화하여 대기정화에 기여하는 가치를 구명하였다. 활엽수림이 전체 식생면적의 약 54%를 차지하였고, 수령구조는 유목내지는 성장과저으이 수목들로 우점하였다. 평균 교목밀도와 기저면적은 각각 17.5주/100m², 2,580cm²이었다. 식생유형 및 영급별 단위면적당 대기정화능은 기저면적의 변화와 유관하여 영급이 높을수록 증가하였고, 동일 영급내에선 대체로 침엽수림보다는 온효림이나 활엽수림이 더 컸다. 식생유형 전체의 단위면적당 평균 CO₂저장량은 293.8t/ha이었고, 경제가치는 147백만원/ha이었다. 연간 흡수량은 CO₂ 24.6t/ha/yr, SO₂ 17.1kg/hr/yr및 NO₂ 43.9kg/ha/yr이었고 연간 경제가치는 13백만원/ha/yr이었다. 전체 식생명적은 총 72.100t의 CO₂를 저장하고 있으며, 해마다 CO₂6.040t/yr, SO₂4.200kg/yr, NO₂10.770kg/yr을 흡수하는 것으로 나타났다. 그 전체면적의 경제가치는 CO₂저장 약 361억원, 연간 CO₂SO₂및 NO₂흡수 31억원/yr에 상당하였다. 남산 도시자연공원은 해마다 시민 약 1,100인의 CO₂배출량, 2,800인의 SO₂배출량,1.160인의 NO₂배출량을 각각 상쇄시키는 중요한 역할을 담당하였다. 본 연구결과는 도시자연공원의 대기정화 가치를 홍보함은 물론, 보강식재 및 관리의예산확보에 필요한 설득력 있는 기반자료가 될 것으로 기대한다. This study quantified C0₂SO₂and N0₂uptake by vegetation for the Namsan Nature Park in Seoul, and explored values for the park to contribute to atmospheric purification. Broad?leaved forest accounted for about 54% of total forest area, and tree-age structure was dominated by a young; growing tree population. Tree density and basal area averaged 17.5 trees/100㎡ and 2,580c㎡/100㎡, respectively. Atmospheric purification per unit area by forest type and age class was greater in older age classes, associated with changes in basal area, and tended to be greater in broad-leaved or mixed forest than in coniferous forest for the same age classes. Mean CO₂storage per unit area for all the forest types and age classes was 293.8 t/ha and economic value of the CO₂storage was \147millions/ha. Annual uptake averaged 24.6 t/ha/yr for C02' 17.1 kg/ha/yr for 802 and 43.9 kg/ha/yr for N02, and economic value of the annual uptake was W 13millions/ha/yr. Total forest area stored 72,100t of CO₂and annually sequestered 6,040t/yr of CO₂4,200 kg/yr of SO₂and 10,770 kg/yr of NO₂. Economic value of atmospheric purification for the entire area amounted to approximately \ 36,100millions for the CO₂ storage, and \ 3,100millions/yr for the annual CO₂SO₂and NO₂uptake. The park played an important role through annually offsetting CO₂emissions from fossil fuel consumption by 1,100 persons, SO₂emissions by 2,800 persons, and NO₂emissions by 1,160 persons. The results from this study are expected to be useful not merely in informing the public of atmospheric purification values of urban nature parks, but in urging the necessity for replanting and management budgets.

도시녹지의 대기환경개선 효과 : 서울시 중구를 중심으로;Focusing on Jung-gu in Seoul

조현길,조용현,안태원 江原大學校 附設 環境硏究所 2003 環境硏究 Vol.20 No.-

This study explored effects of urban greenspace on improving atmospheric environmcnt, which is concerned with CO₂, SO₂and NO₂ uptake, and with reduction of summer air temperatures. The site of this study was focused on Jung-gu in Seoul. Tree density and cover were1.1trecs/l00 m₂and 12.5% respectively for the study area except forest lands. Atmospheric purification by greenspace was associated with changes in tree cover per unit area of each land use type. The mean C02 storage by woody plants was 19.4t/ha, and annual uptake averaged 2.2t/ha/yr for C0₂, 1.9kg/ha/yr for SO₂and 5.0kg/ha/yr for NO₂. Entire tree plantings in the study area played a significant role by annually offsetting CO₂emissions of about 1,8301 from fossil fuel consumption by 330 persons, SO₂emissions of 1,620kg by 1,080 persons, and NO₂emissions of 4,230kg by 450 persons. The smnmer air temperature was 3.6℃ cooler at a location with 54% cover of woody plants and 4.5℃ cooler at a forest site with 100% cover, compared to a place with no planting. A 10% increase of woody plant cover was estimated to decrease slimmer air temperature by approximately 0.6℃ until a certain level of canopy cover. Analyzing data from the Automatic Weather Stations in Seoul revealed that increasing tree cover decreased mean air tern-perature for the smruner season (Jun∼Aug) in a nonlinear function. Woody plant cover was the best predictive variable of summer temperature reduction. The results from this study are expected to be useful in emphasizing the environmental benefits and importance of urban greenspace enlargement, and in urging the necessity for planting and management budgets.

일부지역의 구급차 안전사고에 영향을 주는 요인 분석 : focus on Gwangju Metropolitan City

조진만,오용교,김정현 한국응급구조학회 2002 한국응급구조학회지 Vol.6 No.1

This is a study to evaluate the effects of the safety of ambulance driving and the occurrence of ambulance traffic accidents and to provide basic information for the description of various factors to reduce the ambulance traffic accidents. The major instruments of this study were Korean Self-Analysis Driver Opinionnaire. Questionnaire contains 8 items which measure driver's opinions or attitudees: driving courtesy, emotion, traffic law, speed, vehicle condition, the use of drugs, high-risk behavior, human factor. To take the analysis of data, the total of 187 drivers were investigated ambulance drivers in Gwangju Metropolitan City from 2002. 1. September to 2002. 20. September. The data were analyzed by the path analysis SPSS program. The result are as follows : 1. There was desirable attitude group(58.4%) and undesirable attitude group(41.7%) on safety ambulance driving. 2. It have suggested that risk factors of ambulance traffic accident much affected with emotion and speed control on safety ambulance driving(Y(Accident) = -2.00 + 0.6 X1(Emotion Control) + 0.4 X₂ (Speed control) + E). 3. Almost 92.1% of respondents have agreed to necessity of emergency medical technics for ambulance drivers.

헬륨 마이크로파 플라즈마 토치의 개발과 특성에 관한 연구

曺競鉉,朴勇男 한국교원대학교 환경과학연구소 2002 환경연구논문집 Vol.- No.7

MPT는 최근에 개발된 마이크로파 플라즈마로서 수용매에 강하다. 여러 가지의 변형된 형태의 MPT를 개발하여 구조에 따른 플라즈마의 방전되는 형태를 조사한 결과 이중관 토치는 플라즈마 기체를 적게 소모하며 쉽게 플라즈마가 형성되었으나 토치의 끝이 높은 온도에 견디지 못하고 쉽게 상했다. ICP토치와 같은 형태의 삼중관 토치에 석영관을 중심관으로 사용할 때 가장 안정되고 대칭적인 플라즈마를 형성할 수 있었다. 바탕선을 조사해 본 결과 He MPT는 대기 중으로 돌출되어 대기와 많이 혼합되고 질소에 의해 quenching되는 것으로 보여진다. Membrane desolvator를 탈용매화 장치로 사용하여 헬륨 MPT의 감도를 조사해 본 결과 아르곤 MPT와 비교할 때 대부분의 원소에 대해 검출한계가 10배 이상 높았다. 그러나 여기 에너지가 높은 원소는 비교적 효율적으로 검출할 수 있었다. 헬륨 마이크로파 플라즈마는 적은 양의 플라즈마 기체만 필요하여(약 1.6L/min)경제적이며 매우 안정된 형태를 보여주었다. 플라즈마의 분광특성을 조사한 결과 들뜸온도 4950K, 전자밀도 3.28×10^14㎝^-3로 측정되었다. MPT, which has been developed recently, is very tolerant to aqueous samples. Several types of MPT have been investigated and is found that the double concentric tube could sustain a stable plasma at a low plasma gas flow rate. However, the tip of torch is easily ruined. Triple concentric torch has shown the best stability and the plasma shape, much like that of ICP, especially when the central channel is quartz. The plasma is exposed and mixed with air is suggested from the background spectrum, which leads to quenching of He MPT. Sensitivity of helium MPT equipped with a membrane desolvator has shown 10 times lower than that of Argon MPT for most of elements except for the ones with relatively high excitation energy. He MPT requires small plasma flow rate(about 1.6L/min), stable and simple to use. Excitational temperature and electron number density measured are 4950 K and 3.28×10^14㎝^-3, respectively.

냉동 제대혈 세포의 체외 증폭

김삼용,김철희,배광봉,김현수,박상준,김종숙,윤환중,조덕연 충남대학교 암연구소 1998 癌共同硏究所 硏究誌 Vol.2 No.1

Background : Cord blood(CB), which has no HLA restriction, is an alternative to bone marrow for hematopoietic stem cell transplantation. The use of cord blood, however, is limited by the number of progenitor/stem cells necessary to reconstitute the older child or adult. Therefore, ex vivo expansion of CB could have tremendous impact on diverse clinical settings. We studied the ex vivo expansion of isolated population of CD34_(+) cells from cryopreserved CB cells. Methods : CD34 cells were isolated from cryopreserved CB mononuclear cells. Purified cells were cultured with various combinations of hematopoietic growth factors including erythropoietin(EPO), stem cell factor(SCF), granulocyte-colony-stimulating factor(G-CSF), gra-nulocyte, macrophage-colony-stimulating factor(GM-CSF), interleukin-1β(IL-1β), 1L-3, and IL-6. After 7, 10 or 14 days of culture, the fold increases of colony-forming unit- granu-locyte, macrophage(CFU-GM), burst-forming unit-erythroid(BFU-E), colony-forming unit-mix (CFU-Mix), and high proliferative potential colony-forming cell(HPP-CFC) were evaluated. Results : Ten-day culture with the combination of EPO, SCF, G-CSF, IL-1β, and IL-3 resulted in a median of 60-fold increase of CFU-GM, which was greater than those with the combinations of less than 5 growth factors. The addition of IL-6 or GM-CSF to this combination did not enhance CFU-GM expansion. Ten-day culture was significantly superior to 7-day culture for CFU-GM expansion. Prolongation of culture to 14 days, however, revealed decreased expansion of CFU-GM compared to 10 days. BFU-E and CFU-Mix were expanded to 2~5 folds in 7-day culture with the combination of EPO, SCF, and G-CSF. Further expansion was not achieved in 10-day culture and colonies disappeared in 14-day culture. HPP-CFC was expanded to a median of 7.5 folds in 7-day culture with the combination of EPO, SCF, G-CSF, IL-1β, IL-3, and IL-6. Neither 10-day or 14 day-culture enhanced expansion of HPP-CFU. Conclusion : Cryopreserved cord blood cells maintain ex vivo expansion potential. In our system, 10-day culture with the combination consisting of EPO, SCF, G-CSF, IL-1β, and IL-3 seems to be adequate for hematopoietic progenitor/stem cell expansion from cryopreserved cord blood cells.