반응표면분석법을 이용한 배 퓌레 열수처리 조건 최적화

박민경(Min Kyeong Park),조용식(Yong Sik Cho),장현욱(Hyun Wook Jang) 한국식품영양과학회 2022 한국식품영양과학회지 Vol.51 No.11

본 연구는 열수처리 온도(50, 70, 90°C) 및 열수처리 시간(15, 30, 45분)을 달리하여 배 퓌레를 제조한 후 품질특성을 분석하여 반응표면분석법을 통해 최적의 열수처리 조건을 구하고자 하였고, 중심합성계획법에 따라 총 9가지의 실험점에서 진행하였다. 열수처리 온도 및 시간을 독립변수로 정하고, 품질특성에 관련된 적색도, ΔE값, 일반세균, 대장균군, polyphenol oxidase 활성, 총 폴리페놀 함량, 총 플라보노이드 함량을 종속변수로 설정하였다. 독립변수가 종속변수에 미치는 영향에 대해 분석한 결과, 적색도와 갈변을 나타내는 ΔE값은 각각 -0.38~1.20, 0.97~11.88의 범위로 측정되었고, 반응식의 R2은 각각 0.9754, 0.9818이었다. 일반세균 및 대장균군의 생균수는 각각 0.00~4.91 log CFU/mL, 0.00~4.03 log CFU/mL의 범위였고, 반응식의 R²은 0.9849, 0.9714였다. 갈변의 원인이 되는 polyphenol oxidase 활성은 122.57~235.13 unit 범위였으며, 반응식의 R²은 0.8616의 값을 보였다. 배 퓌레의 유효성분으로 총 폴리페놀 함량 및 총 플라보노이드 함량은 각각 19.33~24.54 GAE mg/100 g, 4.56~5.78 GAE mg/100 g 범위였으며, 이때 반응식의 R²은 각각 0.9181, 0.9097을 나타내었다. 이를 바탕으로 contour map을 superimposing 하여 최적 열수처리 조건을 설정한 결과, 최적화된 열수처리 조건의 온도범위는 69.3~80.4°C, 시간 범위는 16.8~25.8분으로 나타났으며, 최적점은 74.6°C, 20.7분으로 나타났다. 이에 대해 모델의 신뢰성을 검증하기 위해 예측값과 실험값을 비교한 결과, 각 반응변수의 실험값은 모두 예측값의 95% 신뢰구간 및 예측구간 범위에 들어와 모델의 적합성을 확인하였다. This study analyzed the quality characteristics of pear puree by varying the hydrothermal treatment temperature (50, 70, and 90°C) and time (15, 30, and 45 min) and sought to determine the optimal hydrothermal treatment conditions through the response surface methodology. A total of nine experimental points were studied according to the central composite design. The temperature and time were set as independent variables, and the redness, ΔE value, aerobic bacteria, coliform group, polyphenol oxidase (PPO) activity, total polyphenol content (TPC), and total flavonoid content (TFC) related to the quality characteristics were set as dependent variables. The redness and the ΔE value were measured as −0.38∼1.20 and 0.97∼11.88, respectively, and the R² value was 0.9754 and 0.9818, respectively. The R2 value of viable cell counts were 0.9849 and 0.9714 in the aerobic bacteria and coliform groups. The PPO activity was 122.57∼235.13 g/min, and the R² value was 0.8616. The TPC and TFC as active ingredients of pear puree were in the range of 19.33∼24.54 and 4.56∼5.78 GAE mg/100 g, respectively, and the R² values were 0.9181 and 0.9097, respectively. Based on this, the contour map was superimposed to set the optimal hydrothermal treatment conditions. The optimum points derived were 74.6°C and 20.7 min. When the predicted and the experimental values were compared to verify the reliability of the model, all the experimental values of each of the response variables were within the 95% confidence and prediction intervals, confirming the suitability of the model.

은행잎 추출물이 협심증 환자의 내피 세포 기능에 미치는 장단기 효과

배장호,김기식,이인규,김여희,김민수,김기영,남창욱,김윤년,김권배,정시전 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.9

심인성 색전 요인이 없는 뇌경색 환자에서 경식도 심초음파와 Acoustic Quantification을 이용한 대동맥 탄성의 평가

이종민,윤호중,임효영,박지원,김휘열,전희경,문건웅,정욱성,채장성,김재형,최규보,홍순조 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

미맹출 영구 견치 및 소구치 근원심 폭경 추정에 관한 연구

황민성,김정욱,장기택,이상훈 大韓小兒齒科學會 2002 大韓小兒齒科學會誌 Vol.29 No.1

본 연구는 서울시 치과의사횡에서 주관한 건치아동 선발대회 후보의 경석고모형 162쌍을 분석하여 성별에 따라 하악 영구 4전치 근원심 치관 폭경합의 계측치에서 상악 및 하악의 편측 영구 견치 및 제 1, 2 소구치 근원심 폭경합을 추정하는 회귀방정식과 확률표를 구하였다. 그리고 성별간 차이를 비교하여 다음과 같은 결과를 얻었다. 1. 남자와 여자 모두 동일한 악궁 내에서 좌우측 영구 견치 및 소구치의 폭경합은 유의한 차이가 없었다.(p>0.05). 남녀간의 상하악 좌우측 영구 견치 및 소구치의 폭경합의 계측치(x)에서 상악 및 하악의 편측 영구 견치 및 제 1, 2 소구치의 근원심 폭경합(y)을 추정하기 위한 회귀 방정식은 다음과 같았다. 남자 상악 영구 견치 및 소구치 폭경합 : y=10.45+0.53x 남자 하악 영구 견치 및 소구치 폭경합 : y=10.07+0.51x 여자 상악 영구 견치 및 소구치 폭경합 : y=12.65+0.42x 여자 하악 영구 견치 및 소구치 폭경합 : y=11.70+0.42x 남자+여자 상악 영구 견치 및 소구치 폭경합 : y=11.01+0.50x 남자+여자 하악 영구 견치 및 소구치 폭경합 : y=9.87+0.51x The purpose of this study was to establish regression equations and probability charts for predicting the summ of mesiodistal crown diameters of unerupted unilateral canine and premolars from the sum of mesiodistal crown diameters of four mandibular incisors in Korean male and female. The plaster casts of 162 children(75 boys and 87 girls) among the contestees in 1994-2001 Healthy Dentition Contest in Seoul were measured. Sex differences are compare and the following results were obtained: 1. Bilateral comparison of sum of widths of permanent canine and premolars showed no significant differences for either sex(p>0.05). Sum of widths of permanent canine and premolars of male were significantly larger than that of female(p<0.01). 2. Regression equations for the prediction of sum of widths of permanent canine and premolars in each sex were as follows: Male ∑ Maxillary 345 : y=10.45+0.53x Male ∑ Mandibular 345 : y=10.07+0.51x Female ∑ Maxillary 345 : y=12.65+0.42x Female ∑ Mandibular 345 : y=11.70+0.42x Male+female ∑ Maxillary 345 : y=11.01+0.50x Male+female ∑ Mandibular 345 : y=9.87+0.51x

성인 지역사회 폐렴의 원인 미생물에 대한 전향적 다기관 연구 : Legionella, Leptospira, Hantaan virus and Orientia tsutsugamushi

김민자,정희진,손장욱,심희선,박대원,박승철,우준희,강재명,김유겸,신완식,김양리,이환종,김지희 대한감염학회 2001 감염 Vol.33 No.1

Background : Despite rigorous investigations, the etiology of community-acquired pneumonia remains unknown in about 50% of hospitalized patients. The diagnosis of the etiological agent is becoming more challenging and more critical as number of newer pathogens have been recognized in recent years. In the 3-year period prospective study we investigated adult patients with community-acquired pneumonia for Legionella, Leptospira, Hantaan virus and Orientia tsutsugamushi as potential etiologic agents. Methods : A prospective multicenter study was performed from May 1997 to April 2000. A total of 431 patients with community-acquired pneumonia under the inclusion criteria were examined for specific microbial diagnosis; sputum culture and PCR, and serologic teats including indirect immunofluorescence antibody (IFA) test for Legionella, and hemagglutination tests for Leptosoira, Hantaan virus and O. tsutsugamushi. Etiologic diagnosis was determined on the basis of the review of case record forms and specific laboratory diagnostic criteria. Results : During the study period a total of 385 sputum and 283 serum samples were examined. Legionella pneumonia was diagnosed in 2.3% (10/431) of the cases examined : 1.4% cases with PCR-positive (5/367) and 2.1% with positive IFA test (6/283). Leptospirosis and scrub typhus were diagnosed in 0.4% (1/252) and 2.0% (5/252), respectively. All 5 cases with scrub typhus occurred in late fall, and rash or eschar was not found. None of cases was Hantaan virus infection. Conclusion : The results suggest that Legionella, Leptospira, and O. tsutsugamushi should be considered in the etiologic diagnosis and empirical antibiotic therapy of community-acquired pneumonia. (Korean J Infect Dis 32:24∼31, 2001)

위상최적화를 이용한 트레일러의 경량설계

안서욱,이신영,윤민수,장강원 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

A new design for a lightweight flatbed trailer with high bending and torsional stiffness is presented by using an integrated CAE-based optimization procedure. The integrated design procedure consists of two main steps: topology optimization and thickness optimization. During topology optimization, a creative frame layout different from existing ladder-type frames can be obtained by searching the best layout out of all possible layouts of a simplified design domain model. After approximating the result of topology optimization as a thin-walled structure, the approximated thicknesses of the plates are optimized to minimize the mass of a trailer.

TNBS에 의해 유도된 대장염에서 ERK의 역할에 관한 연구

유민욱,권영미,장성조 圓光大學校 醫科學硏究所 2005 圓光醫科學 Vol.20 No.1

임상 증상이 심하지 않은 심낭 삼출 환자의 장기 추적 결과

배장호,김기식,강미숙,남명희,김미정,김민수,김기영,님창욱,김윤년,김권배,정시전,김여희 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.7

공동주택에 적용되는 공기식 열교환기의 성능평가에 관한 연구

김상민,안병욱,손장열 대한건축학회 2005 대한건축학회논문집 Vol.21 No.3

Indoor Air Quality has been significantly degraded due to the improvement of the airtightness of residential and commercial combined high-rise apartment buildings. In order to handle the problems related to insufficient ventilation, the application of mechanical ventilation system is required in detached residences or apartments in the country. As an alternative, air-to-air heat recovery ventilators are used at initial stage for energy conservation using waste heat recovery and the improvement of IAQ in high-rise apartments, currently being more widely used even in apartments and detached residences. Due to this trend, relevant institutes and organizations are making standards for the evaluation of HRV(Heat Recovery Ventilator) performance, but research related to the evaluation of HRV performance are not sufficiently done in this circumstance before applying in real buildings. Therefore, the purpose of this study is to compare and evaluate international and domestic standards for the evaluation of HRV performance, and to provide guideline for the adequate selection of effective HRV by evaluating the performance synthetically in terms of major items.

서울시에서 산발적으로 분리된 Salmonella enterica Serotype Typhi 임상분리균주들의 분자역학적 분석

이희무,김철현,손장욱,김민자,박미선,이복권 대한감염학회 2000 감염 Vol.32 No.5