쌀, 조, 수수 및 콩의 食餌가 흰쥐의 成長 및 血液性狀에 미치는 影響

한백수,주현규,사동민,박병순,박기웅 선문대학교 첨단과학기술연구소 1996 첨단과학기술연구소 논문집 Vol.1 No.1

쌀, 조 수수, 및 콩의 식이가 흰쥐의 성장 및 혈액 성상에 미치는 영향을 조사하기 위하여, 평균체중 180g의 Sprague-Dawley계 rat(♂) 각 5마리씩을 대조군(T_(0)), 쌀(T_(1)), 조(T_(2)), 수수(T_(3)), 콩(T_(4))급이군등 5개군으로 나누어 실온에서 6주간 사육하면서 사료섭취량, 급수량, 증체량과 6주후의 혈액상의 변화틀 조사하였다. 사료 섭취량은 대조군이 각 처리 실험군보다 높았으며 물의 급수량도 동일한 결과이었으며 그 순위는 쌀, 조, 콩, 수수 순으로 감소하였으며, 각 처리군의 증체량은 대조군 보다 낮았으며, 특히 수수는 초기보다 감소하였고, 각 처리군의 사료효율은 대조군보다 낮았으며 특히 수수처리군이 타 처리군보다 낮았다. 연액성상의 변희는 대조군에서는 큰 변화가 없으나 수수군에서 BUN, HOT지 다른군보다 높았으며 쌀의 처리군은 creatinine치가 높았고 조에서는 혈당치가 낮았으며, 콩에서는 LDH는 높았고, HGB, HCT, PI.T, RBC가 낮았고, 특히 콩 수수에서는 혈액상의 변화가 가장 컸으며 다른 실험군과 비교하였을 때 통계적인 유의성이 인정되었다. This study was conducted to investigate the effects of rice, millet, sorghum and soybean diet on the growth rate, daily intake feed ratio and change in hematology of male rats. The experimental male rats of 180g average weight were fed on control (T_(0)), rice (T_(1)), millet (T_(2)), sorghum (T_(3)) and soybean diet (T_(4)) for 6 weeks. The amount of daily feed and water intake supply in each diet group is higher than that of control group to as shown in the following order: rice, millet, soybean, sorghum. The growth ratio of each diet group is lower than that of control group. Especially, sorghum made each diet group reduce the weight even more than the initial weight. Control group is lower than each diet group in regard to the effective ratio of feed. Especially, the sorghum group is lower than other groups. Control group remained same in the change of hematology, however, sorghum group is higher than other groups for BUN, HCT. Rice group is higher in creatinine and millet group is lower in glucose content of serum than any other groups. Soybean group is higher in LDH but lower in HGB, HCT, PLT, RBC than control group. Especially, the soybean and sorghum groups showed a big change in hematology and had the statistic significance in comparison to other groups.

수술을 시행한 치루환자 277예에 대한 분석

박현규,김한선 대한대장항문학회 1996 Annals of Coloproctolgy Vol.12 No.3

쌀의 수침시간 및 증자시간에 따른 가래떡이 품질 특성

유진현,한규홍 한국조리과학회 2004 한국식품조리과학회지 Vol.20 No.6

The effects of soaking and steaming time on the quality characteristics of Korean rice cake (karedduk) were investigated. As the soaking time increased, the water-binding capacity and rice floor solid content also increased. After 8 to 10 hr soaking, 75.2 to 76.8% of particles were smaller than 40 gm, and 23.2 to 24.8% within the range of 40 to 100 ㎛. Therefore, an extended soaking time reduced the particle size. Texture is an important characteristic used to differentiate karedduk varieties, and is considered by the consumer as a determinant of the overall quality and preference. The hardness, cohesiveness, gumminess and chewiness of the karedduk structure decreased with increasing steaming time, but the springiness was highest after a 40 min steaming time. The overall texture properties were also more acceptable with 8 and 10 hrs soaking times. The L value of the karedduk decreased with increasing steaming time, but the b value increased. Also, the results of the sensory evaluation showed that an 8 hr soaking time and 40 min steaming time produced more acceptable karedduk in terms of whiteness, texture, springiness, chewiness and overall acceptability.

분광광도법과 PAN을 이용한 미량 망간(Ⅱ)의 분석에 관한 연구

함용규,한현택,정창웅 순천향대학교 기초과학연구소 1999 순천향자연과학연구 논문집 Vol.5 No.2

A selective and highly sensitive spectrophotometric method has been investigated for the determination of trace manganese(Ⅱ) with 0.1% PAN in 0.001N-HNO₃and 10% potassium sodium tartrate solution. Mn(Ⅱ)-PAN complex was extracted into chloroform and this complex has maximum absorbance at 560㎚. Beer's law applied in the range of 20 ㎍ of Mn(Ⅱ) and the molar absorptivity is 4.6 × 10⁴L/㏖·㎝.

PID 제어기의 퍼지 이득 조정

탁한호,추연규,김현덕 진주산업대학교 1999 산업과학기술연구소보 Vol.- No.6

The purpose of this paper is to find PID parameters. The model of controller is designed by Matlab-Simulink program and each parameter of PID is estimated automatically by the Fuzzy controller. The simulation is carried out on FGS(Fuzzy Gain Scheduling), and then this is compared and analyzed with the simple PID controller.

다발성 말초신경병증의 조기진단 : 적외선 체열촬영검사와 전류지각역치검사의 조합진단 Combination Diagnosis Using by Digital Infrared Thermogram and Current Perception Threshold

이삼규,김재형,최인성,이소영,한재영,조성렬,김재휴,노성만,정민영,정동진,김현성 全南大醫大 2001 전남의대학술지 Vol.37 No.3

물결합재비 및 단위수량에 따른 고유동콘크리트의 제공학적 특성에 관한 실험적 연구

김규용,한장현,신동주,신홍철,김무한 忠南大學校 産業技術硏究所 1998 산업기술연구논문집 Vol.13 No.1

Recently the study on high flowing concrete which has high workability and non-compacting is being proceeded actively in the university and corporative laboratory. There are some cases that has been applied to the field. This high flowing concrete has higher fluidity and segregation resistance than Plain or flowing concrete. And it is being focused as a remarkable know-how which can make high-quality concrete and reduction effect of labor force. This properties of high flowing concrete are influenced by the relationship of several factors; binder content water binder ratio and unit water content. It is the aim of this study to propose reference data at mix design of high flowing concrete, after comparing and analyzing the fluidity and strength properties of high flowing concrete according to water binder content ratio and unlit water content.

시상부위에 발생한 단일성 뇌농양 : 증례 보고 및 문헌고찰 Report of Two Cases and Review of the Literature

곽호신,김동규,이상형,정희원,이현구,김현집,한대희 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.12

The authors present two cases of solitary thalamic abscess which were intially diagnosed as malignant thalamic glioma. After treatment with steroids and osmotic agents, the patients' clinical conditions improved after two to three days. However, sudden deterioration of consciousness level developed and the CT scan showed acute hydrocephalus with increment of thalamic low-density lesions. We performed extraventricular drainage and obtained CSF containing numerous inflammatory cells. This suggested the possibility that the lesion was a pyogenic abscess. which progressed to ventriculitis, rather than a malignant glioma. Stereotactic aspiration of the lesion confirmed thalamic abscess. These findings and review of previous reports of thalamic abscess suggested that early diagnosis and stereotactic drainage of the thalamic abscess is of primary importance.

백혈병 세포를 이용한 종양-림프구 혼합면역반응의 임상적 의의

김희제,조현일,김태규,한훈,김춘추,민우성 대한조혈모세포이식학회 2000 대한조혈모세포이식학회지 Vol.5 No.1

본 연구는 골수성 백혈병세포와 공여자 유래의 말초 혈액 단핵구를 실험관 내에서 배양하여 백혈병 특이 세포 독성 T 세포를 HLA 일치 형제 공여자로부터 유도하고, 유도된 T 세포의 특성을 규명하여 조혈모세포이식 후의 임상적인 소견과의 연관성을 조사하고자 하였다. 만성기 5례, 가속기 3례, 급성기 2례를 포함하는 10례의 만성 골수성 백혈병 환자들과 1차 완전 관해 상태에 있는 2례의 급성 골수성 백혈병 환자들의 말초혈액에서 수상돌기 세포를 유도하여 항원제시세포로 사용하였다. 백혈병 세포에 대한 세포 독성 T 세포의 효과적인 유도는 급성 골수성 백혈병, 만성 골수성 백혈병의 만성기와 급성기, 가속기의 순서였다. 세포 독성은 세가지 표적 세포인 K562 세포주, 백혈병 세포와 환자의 PHA 자극세포에 대한 세포독성 실험을 통해 세포독성 T 세포에 의한 것인지 또는 자연 살해 세포 (NK 세포)에 의한 것인지 구별할 수 있었다. 세 가지 표적세포에 대한 세포살해는 결과를 종합하여 동종 조혈모 세포이식 후 백혈병의 제발 가능성을 예측할 수 있었다. 즉 세가지 표적세포들 중 한 가지에서라도 양성 반응을 보인 경우 이식편대 백혈병 효과로 인해 백혈병 재발률이 낮았다. 2례의 만성 골수성 백혈병 가속기 환자들에서 유도된 백혈병성 수상돌기 세포들은 세포의 형태학적 소견과 유세포 분석기를 사용한 면역 표현형이 수상돌기 세포와 동일하였으나 이를 이용해 유도한 세포독성 T 세포는 유의한 활성을 나타내지 않았다. 결론적으로 백혈병 세포에 대한 공여자 기원의 항 백혈병 세포독성 T 세포는 Interleukin-2로 자극하여 실험관내 배양이 가능하며, 이를 통해 질환의 특성이나 백혈병 세포의 생물학적 이질성에 따른 세포 살해능의 다양성을 규명할 수 있을 것으로 사료된다. Background:Allogeneic bone marrow transplantation (BMT) is an effective treatment for a large number of patients suffering from malignant hematological disorders. An immune-mediated graft-versus-leukemia (GVL) effect is an important feature of this treatment modality. Although numerous clinical and experimental data have given evidence for both T and NK cells involved in this phenomenon, leukemic relapse and graft-versus-host disease (GVHD) mediated by T cells still remain the major problems of allogeneic BMT. In this study, we tried to define the characteristics of anti-leukemic CTLs and to evaluate the clinical implications of the cellular immunity in leukemic patients. Methods:Leukemic cells were incubated concurrently with peripheral mononuclear cells isolated from HLA-matched sibling donors. Cytotoxic T lymphocytes (CTLs) have been generated from peripheral blood cells of 12 patients with chronic myelogenous leukemia (CML) including 5 in chronic phase (CP), 3 in accelerated phase (AP), 2 in blastic crisis (BC) and 2 patients with acute myelogenous leukemia (AML) in first complete remission. The activity of CTLs and NK cells was measured by 51Cr release assay using autologous leukemic cells, K562 cell line and patient's PHA blasts as target cells. Results:The efficacy of generating CTLs against leukemic target cells were AML, CML-CP and CML-BC, CML-AP in order. Low leukemia relapse events was found to be associated with the strong intensity of cytotoxcity for K562 cell lines, and in addition to this, if we combine the cytotoxicity effects for all thee target cells, the possibility of relapse after allogeneic stem cell transplantation (SCT) was significantly predictable. Any significant association of the cytotoxicity against three target cells with GVHD was not found. Sex-matching or mismatching between donor and recipient did not affected on the NK cell activity. Conclusion:Our results demonstrated that donor-derived antileukemic cytotoxic T-cells against patient's own leukemic cells are producible in vitro and the activity of CTLs and NK cells may be variable according to disease-specificity or to biological heterogeneity of leukemia. If the specific, stable and reproducible anti-leukemic CTLs could be generated in vitro, these CTL lines could be used for the treatment of relapsed or predictable relapse high-risk leukemia after allogeneic BMT and for post-mini-transplantation immunotherapy in the near future.

중학교 가정교과의 열린교육 활성화를 위한 수업 모듈 및 웹 기반 교육자료 개발

신상옥,유태명,한규정,윤지현,홍정숙,김유정,양정혜 한국 가정과 교육 학회 2000 한국가정과교육학회지 Vol.12 No.3

This study is about open and secondary level Home Economics Education which is applicable to field and which includes the characteristics, purpose and problems of each open education. secondary education and home economics education. Based on the ideology of open education, this study will identify the meaning of openness in terms of Home Economics Education reconstructing meaning. purpose, characteristics, curriculum paradigm and curriculum. The instructional model and module which use web, will be Presented as the results of the reconstruction works. The open instructional module in Home Economics Education, which will be operated on the web, is consisted of 1)setting the orientation of curriculum development, 2)instructional model development. 3)rebuilding the Home Economics Education curriculum 4)development of instructional modules and web-based materials and 5)construction of the web-site . Six instructional module begin with critical/emancipatory curriculum Paradigm in open Home Economics Education. use module as a unit of class management instead of 1 class. facilitates nest-type integration which is applied from open education keeping the nature of Home Economics Education. and focus on practical problem and problem solving through reconceptualization with dialectical perspective on individual, family and society. The practical problem solving model has four steps : Identifying practical problems. Understanding the contexts of Problem, Searching for solutions and examining its consequences . Action and evaluation . The web-site has to be developed based on the six instructional module includes those issues : self-identification for reinforcing autonomy and self-esteem. living with famity. living with friends, autonomous living. healthy living, and understanding sexuality.