동결견(凍結肩) 환자의 동서협진 치료의 임상효과 비교연구 : 견관절 가동운동범위(ROM) 변화를 중심으로

남동우,김행범,양동훈,임사비나,김건식,이두익,이재동,최도영,이윤호 경희대학교 동서의학연구소 2006 東西醫學硏究所 論文集 Vol.2006 No.-

Objectives : To establish an effective collaborate medicine treatment of acupuncture and western medicine for treating frozen shoulder patients. Methods : 59 voluntary patients were randomly assigned to Eastern treatment group(E group, n=22), Western treatment group(W group, n=17) and East-West treatment group(EW group, n=20). The E group received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection, twice a week for 4 weeks. The EW group received acupuncture and injection treatment including nerve block. All groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after treatment based on the change in shoulder Range of Motion(ROM) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). The obtained data were analyzed and compared. Results : The patient's satisfaction scores were E group 5.67, W group 7.73 and EW group 7.67. The E group and the EW group showed significant improvement in abbduction, adduction and flexion(p<0.05). The W group showed significant improvement in adduction(p<0.05). Abduction significantly improved(p<0.05) in the EW group compared to E group and W group. Flexion also showed improvement in the EW group, but the difference among the 3 groups was statistically insignificant. The three group's difference of change in extension and adduction was insignificant(p>0.05). Conclusion : Acupuncture and nerve block alone significantly improved ROM in frozen shoulder patients. Also collaborate treatment of acupuncture and nerve block significantly improved ROM in frozen shoulder patients. But the difference of the three treatments were significant only for improving abduction(p<0.05).

만성 견비통에 대한 동씨침 치료의 무작위 대조군의 임상 연구

김찬영,권나현,신예지,남동우,김건형,김종인,최도영,이윤호,이재동 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2007 東西醫學硏究所 論文集 Vol.2007 No.-

Objectives : To observe the effect of acupuncture treatment in chronic shoulder pain patients. Methods : 36 voluntary patients were randomly assigned to an acupuncture treatment group(E GrouP, n=18) and a control group(C GrouP, n=18). The E Group patients received acupuncture treatment on LI_(15), TE_(14), GB_(21) and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for four weeks. The C Group patients received no treatment. All patients in both groups were instructed to practise self exercise in their daily lives. Evaluations were made at baseline and after four weeks of study. The Constant Shoulder Assessment(CSA), Shoulder Pain and Disability Index(SPADI) and the patient's subjective pain was measured by Visual Analogue Scale(VAS). The obtained data was analyzed. Results '. The E Group showed significant(p<0.05) improvement in CSA, SPADI and VAS after four weeks of treatment. The C Group showed significant(p<0.05) improvement in CSA, but the change of SPADI and VAS was insignificant(P>0.05). CSA and SPADI of E Group significantly(p<0.05) improved compared to the C GrouP, but the difference of VAS change in the two groups was insignificant(p>0.05). Conclusions : Four weeks of acupuncture treatment significantly improved CSA, SPADI and VAS. The improvement of CSA and SPADI was significant(p<0.05) compared to untreated patients.

동결견(凍結肩) 환자의 동서협진 치료의 임상효과 비교연구 - 견관절 가동운동범위(ROM) 변화를 중심으로 -

남동우,김행범,양동훈,임사비나,김건식,이두익,이재동,최도영,이윤호,Nam, Dong-Woo,Kim, Haeng-Beom,Yang, Dong-Hoon,Lim, Sa-Bi-Na,Kim, Keon-Sik,Lee, Doo-Ik,Lee, Jae-Dong,Choi, Do-Young,Lee, Yun-Ho 대한침구의학회 2006 대한침구의학회지 Vol.23 No.5

Objectives : To establish an effective collaborate medicine treatment of acupuncture and western medicine for treating frozen shoulder patients. Methods : 59 voluntary patients were randomly assigned to Eastern treatment group(E group, n=22), Western treatment group(W group, n=17) and East-West treatment group(EW group, n=20). The E group received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection, twice a week for 4 weeks. The EW group received acupuncture and injection treatment including nerve block All groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after treatment based on the change in shoulder Range of Motion(ROM) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). The obtained data were analyzed and compared. Results : The patient's satisfaction scores were E group 5.67, W group 7.73 and EW group 7.67. The E group and the EW group showed significant improvement in abbduction, adduction and flexion(p<0.05). The W group showed significant improvement in adduction(p<0.05). Abduction significantly improved(p<0.05) in the EW group compared to E group and W group. Flexion also showed improvement in the EW group, but the difference among the 3 groups was statistically insignificant. The three group's difference of change in extension and adduction was insignificant(p>0.05). Conclusion : Acupuncture and nerve block alone significantly improved ROM in frozen shoulder patients. Also collaborate treatment of acupuncture and nerve block significantly improved ROM in frozen shoulder patients. But the difference of the three treatments were significant only for improving abduction(p<0.05).

하수슬러지 중 노말핵산추출물질(HEM)함량 분석 및 토양 사용시 연간 오염부하량 추정

남재작,박우균,임동규,이상학 한국환경농학회 2002 한국환경농학회지 Vol.21 No.1

하수슬러지 중에 존재하는 HEM에 대해 분석하고, 이를 토양에 사용할 때 발생하는 연간 오염부하량에 대해 추정하였다. 전국의 하수처리장에서부터 수집된 하수슬러지 시료 84점에 대해 분석한 HEM의 평균함량은 27.7±26.5 g/㎏이었고, 최소 1.05에서 최대 194 g/㎏을 나타내어 분석시료간에 큰 편차를 보였다. 하수 처리장이 위치한 도시의 규모에 따라 5단계로 나누었을 매 HEM의 함량은 광역시, 대도시, 중도시, 소도시, 농촌지역에 각각 22.7±16.7, 33.3±25.8, 22.0±8.7, 31.0±30.8, 27.7±25.1 g/㎏을 나타내었다. 미국 EPA의 하수슬러지 토양시용량 기준을 적용하여 농경지, 산림, 공공용지, 개량용지로 분류하고 각각 7,000, 26,000, 18,000, 74,000 ㎏/㏊ (건물량 기준)를 하수슬러지 최대 사용량으로 가정하여 HIM의 연간 오염부하량울 계산하였다. 건물량 기준으로 시용량이 7,000 ㎏/㏊인 농경지의 경우 최대 1,032 ㎏/㏊의 HEM 부하량을 나타내었고, 개량용지 시용기준인 74,000 ㎏/㏊를 적용한 경우 HEM의 연간 오염부하량은 10,908 ㎏/㏊으로 추정되었다. 그 외 산림기준을 적용할 때는 최대 3,832㎏/㏊, 공공 용지 기준을 적용할 때는 최대 2,653 ㎏/㏊의 연간 오염부하량이 추정되었다. To estimate annual pollutant loading rate of n-hexane extractable material (HEM) to soil 84 sewage sludge samples were analyzed. The average content of HEM was 27.7±26.5 g/kg, and ranged from 1.05 to maximum 194 g/kg. According to the number of population of the city the areas were classified as five regions, i.e. big, large, middle, small, and rural area in which the waste water treated plants were grown. The contents of HEM were 22.7±16.7, 33.3±25.8, 22.0±8.7, 31.0±38.8, 27.7±25.1 g/kg, in big, large, middle, small, and rural area, respectively. The applicated areas with sewage sludge to land also were divided as 4 sites by US EPA criteria such as agricultural, forest, public contact sites, and reclamation site. The quantitation of annual pollutant loading rate was estimated using a function (99 percentile concentration = X￣+ 30) when the application amounts were in dosages of 7,000, 26,000, 18,000, 74,000 kg/ha in 5 regions, respectively. The annual pollutant loading rate of HEM to soil by sewage sludge application was maximum 1,032, 3,832, 2,653, and 10,908 kg/ha in agricultural, forest, public contact sites, and reclamation site, respectively.

유착성 관절낭염에 대한 침 및 신경차단술 처치의 임상적 관찰

남동우,임사비나,김종인,김건식,이두익,이재동,이윤호,최도영 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2007 東西醫學硏究所 論文集 Vol.2007 No.-

Objectives : To observe the effect of acupuncture and nerve block combination treatment on adhesive capsulitis patients. Metbods : 59 voluntary patients were randomly assigned to acupuncture treatment group(E group ,n=22), nerve block treatment group(W group, n=17) and acupuncture and nerve block combination treatment group(EW grouP, n=20). The E group received acupuncture treatment on LI15, TE_(14), GB_(21) and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection twice a week for 4 weeks. The EW group received the same treatment as the W group and after 5minutes of rest, successively received the treatment identical to that of E group. AU three groups were instructed to practice groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after 1, 2, 3 and 4week treatment. Constant Shoulder Assessment(CSA), Shoulder Pain and Disability Index(SPADI), Range of Motion(ROM), the patient's treatment satisfaction measured by Visual Analogue Scale(VAS) and Digital Infrared Thermographic Imaging(DITI) were used as assessment tools. The obtained data were analyzed and compared. Results : The E group showed significant improvement(p<0.05) on CSA, SPADI, VAS and DITI. As for ROM, Adduction and Extension improved significantly(p<0.05). The W group showed significant improvement(p<0.05) on CSA, SPADI, VAS and DITI. As for ROM, Abduction and Extension improved significantly. The EW group showed significant improvement(p<0.05) on CSA, SPADI and VAS. As for ROM, Adduction, Abduction, Extension and Flexion improved significantly. The improvement of CSA, VAS and Abduction ROM in the EW group was significant1y(P<0.05) superior compared to the groups treated with single type of treatment. Conclusion : It is suggested that acupuncture and nerve block combination treatment for adhesive capsulitis patients is more effective than the two single treatments. Through further studies, the acupuncture and nerve block combination treatment model may be developed into East-West Collaboration Model in treating adhesive capsulitis.

유착성 관절낭염 치료에 있어서 한방 치료와 양방 치료의 임상적 고찰 : 동서협진 모델 개발을 위한 기초 연구를 중심으로

남동우,정인태,김주희,박유선,임사비나,이두익,이재동,이윤호,최도영 경희대학교 동서의학연구소 2006 東西醫學硏究所 論文集 Vol.2006 No.-

Objectives : To observe the effect of acupuncture treatment and western medical treatment on frozen shoulder patients. Methods : 39 voluntary patients were randomly assigned to the Eastern treatment group(E group, n=22) and the Western treatment group(W group, n=17). The E group received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection, twice a week for 4 weeks. Both groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after treatment using Constant Shoulder Assessment(CSA), Shoulder Pain and Disability Index(SPADI) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). The obtained data were analyzed and compared. Results : The E group showed significant improvement(p<0.05) according to the CSA and SPADI. The patient's satisfaction scored 5.67 on a scale of 10. The W group showed significant improvement(p<0.05) according to the CSA and SPADI. The patient's satisfaction scored 7.73. But the difference between the two groups were insignificant according to CSA and SPADI. Conclusion : Both acupuncture and nerve block treatment significantly improved frozen shoulder. But the difference of the two treatments was insignificant.

치수생활력 검사 방법으로서 laser Doppler flowmeter의 신뢰도

남순현,김영진,남동우 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.4

미완성 치근을 가진 영구 중절치에 대한 치수생활력 검사에서 LDF의 신뢰도를 알아보기 위해 8-9세의 취학 아동 35명을 대상으로 전기치수 검사 및 LDF에 의한 치수생활력 검사를 시행하고 대조군으로 23-24세 성인 남녀 35명의 상악 영구중절치를 대상으로 동일한 검사를 시행하였다. 미완성 치근단을 가진 치아는 방사선 사진상 moorrees등의 연구를 참조하여 치근 발육 5및 6단계로 한정하였다. 전기치수검사는 최초의 감각이 나타나는 시기를 역치로 정하였으며, 대상 치아당 3회 이상 실시하였고, 위음성 반응의 가능성 때문에 검사간 간격은 3분 이상으로 하였다. LDF는 안정된 signal이 나타날 때 까지 5분 이상 관찰하였으며, 안정상태 도달 후 5분 이상 측정하였다. 모든 반응인자의 정규 분포를 확인한 다음, 대조 치아 및 시험 치아간 LDF및 전기치수검사의 역치를 student t-test를 이용하여 비교하였다. 1. 전기치수 검사시 미완성 치근에서는 28.4%에서만 반응이 나타났으며, 완성 치근의 경우 100%에서 반응이 나타났고, LDF에 의한 검사시 미완성 치근 및 완성 치근 모두에서 100% 반응이 나타났다. 2. 완성 치근 및 미완성 치근을 가진 치아의 전기 치수검사 역치는 미완성 치근을 가진 치아가 큰 값을 나타내며 유의한 차이가 있었다. (p<0.01). 3. 완성 치근 및 미완성 치근을 가진 치아 사이의 LDF 수치는 유의한 차이가 나타나지 않았다 (p>0.05). The purpose of this study was to evbaluate the reliablity of laser Doppler flowmeter on the permanent maxillary central incisors with open apex. Laser Doppler flowmeter and electric pulp tests were done in 35 elementary students aged between 8 and 9 years and 35 females and males aged between 23 and 24 years. Teeth with open apex were confined to root developmental stage 5 and 6 by Moorrees classification. The threshold of electric pulp tests was decided the time of tingling sensation. More than three different electric pulp tests applied on every teeth with more than 3 minutes interval between each teeth due to the false response. Laser Doppler flowmeter test stablilzation and observation stages took more than 5 minutes each LDF values and electric pulp test thresholds were analyzed with student t-test. The results were as follows: 1. The electric pulp test threshold on teeth with immature and mature roots showed 28.4% and 100% response respectively, and the the LDF values on teeth with immature and mature roots showed 100% response. 2. The EPT thresholes on teeth with immature roots were larger than thresholds on teeth with mature roots(p<0.01). 3. No significant differences were found in the LDF values on teeth with immature and mature roots.

점액성 대장 및 직장암의 임상 병리학적 고찰

신동우,김남규,민진식,김호근,양우익 대한대장항문학회 1997 Annals of Coloproctolgy Vol.13 No.3

Saccharomyces cerevisiae에서 Trichoderma Endoglucanase의 발현과 분비

남수완,김병우,신동하,김재범,신지원,정대균,정춘수 동의대학교 기초과학연구소 1999 基礎科學硏究論文集 Vol.9 No.1

The endoglucanase gene, egl6, of Trichoderma sp. was connected with the yeast ADH1 promoter, and the resultant plasmid, pVT-C4, was introduced into three S. cerevisiae host strains (YNN27, 2805, and SEY2102). Among each 80 transformants, the cell growth and expression level of endoglucanase were compared in test-tube cultivation, and three respective transformants for each host cells showing the highest expression level and cell growth were selected. When three recombinant yeast cells were batchwise cultivated for 48 hr in flask, the total activities of endoglucanase expressed were about 1140 unit/1 with 2805/pVT-C4, 1020 unit/l with SEY2102/pVT-C4, and 590 unit/l with (YNN27/pVT-C4. Irrespective of host strain, about 80% of the expressed endoglucanase was detected in the extracellular medium. In addition, it was also found that the recombinant enzyme was secreted into the culture medium as two major forms of lightly and heavily glycosylated proteins.

CERN LEP 가속기에서의 ALEPH 검출기를 통한 B^0_s 중간자 탐색

남지우,김동욱,노상률,최영일 성균관대학교 기초과학연구소 1997 論文集 Vol.48 No.-

We have searched for B^0_s meson using about 4.2 million hadronic Z^0 decays collected by the ALEPH detector at LEP from 1991 to 1995. The B^0_s decay modes include B^0_s → D^-_sπ^+, B^0_s → D^-_sπ+π^-π^+ (D^-_s a^+_1, D^-_s ρ^0π^+). There were eight events in the signal region with some background. Two clean B candidate events were found in the eight events. They are B^0_s →D^-_sπ^+, B^0_s →D^-_sρ^0π.