연구논문 : 내륙습지 기능의 우선순위 결정

이승준 ( Seung Jun Lee ),최현아 ( Hyun Ah Cho ),이우균 ( Woo Kyun Lee ),이종렬 ( Jong Yeol Lee ),전성우 ( Seong Woo Jeon ),김준순 ( Joon Soon Kim ) 한국환경영향평가학회 2014 환경영향평가 Vol.23 No.3

In this study, the functional priority of wetlands was determined through analysis of previous research. To determine relative importance, three processes were performed. First, quantitative values from the case studies were normalized. Second, non-quantitative values were prioritized based on standard criteria. Third, equal weight was applied as long as there was no special consideration regarding a particular value`s disproportionate priority in the research. Finally, results were grouped into large, medium, and small classes. In this study, the functions of the medium class were found to be the most significant, in the following order of priority: water supply and ground water recharge; culture and recreation; biodiversity; product; water quality control; flood control; erosion control; moderation of climate change; and provision of biochemical matter. To verify these results, we compared our findings with those of an assessment that used the Rapid Assessment Method (RAM) on the same type of study area. Whereas this comparison indicated some correlations by the culture, water storage, and genetic sustainability functions, it suggested a lack of such relationship by the water purification and flood prevention functions.

VUV 이오나이저용 Ca-Sr-Ba계 산화물 캐소드에 낮은 일함수를 갖는 금속산화물 첨가의 영향

박승규,이종혁,김란희,정주형,한완규,이수현,전성우,김대준,김도윤,이광섭,Park, Seung-Kyu,Lee, Jonghyuk,Kim, Ran Hee,Jung, Juhyoung,Han, Wan Gyu,Lee, Soo Huan,Jeon, Sung Woo,Kim, Dae Jun,Kim, Do-Yun,Lee, Kwang-Sup 한국재료학회 2019 한국재료학회지 Vol.29 No.4

There are several manufacturing techniques for developing thermionic cathodes for vacuum ultraviolet(VUV) ionizers. The triple alkaline earth metal emitters(Ca-Sr-Ba) are formulated as efficient and reliable thermo-electron sources with a great many different compositions for the ionizing devices. We prepare two basic suspensions with different compositions: calcium, strontium and barium. After evaluating the electron-emitting performance for europium, gadolinium, and yttrium-based cathodes mixed with these suspensions, we selected the yttrium for its better performance. Next, another transition metal indium and a lanthanide metal neodymium salt is introduced to two base emitters. These final composite metal emitters are coated on the tungsten filament and then activated to the oxide cathodes by an intentionally programmed calcination process under an ultra-high vacuum(${\sim}10^{-6}torr$). The performance of electron emission of the cathodes is characterized by their anode currents with respect to the addition of each element, In and Nd, and their concentration of cathodes. Compared to both the base cathodes, the electron emission performance of the cathodes containing indium and neodymium decreases. The anode current of the Nd cathode is more markedly degraded than that with In.

토지피복지도를 활용한 농업비점오염원 오염부하량 산정에 관한 연구

유지은,김윤지,성현찬,이경일,최지용,전성우,Yu, Jieun,Kim, Yoonji,Sung, Hyun-Chan,Lee, Kyung-il,Choi, Ji-yong,Jeon, Seung-woo 한국환경과학회 2020 한국환경과학회지 Vol.29 No.12

Non-point source pollutants have characteristics the render them difficult to manage owing to the uncertainty of flow paths. As agricultural non-point sources account for more than 57% of non-point source pollutants, the necessity for management is increasing. This study examines the possibility of utilizing land cover maps to suggest a more appropriate method of setting management priority for agricultural non-point sources in the Daecheong Lake area and draws implications by comparing the results derived using the cadastral map, as mentioned in the TMDL Basic Policy. To define the prioritized areas for management, the pollution load was calculated for each subbasin using the formula from the TMDL technical guidelines. As a result, the difference in the average pollution load between the land cover map and cadastral map ranged from 11.6% to 21% among the subbasins. In almost all subbasins, there were differences in the ranking of management priorities depending on the land information that was used. In addition, it was found that it was reasonable to use the level 3 land cover map to calculate the load generated by the land system for examining the implementation goals and methods of each data and comparing them with satellite images.

Ferulic Acid와 관련 페놀화합물의 암세포주에 대한 독성억제효과

한두석(Du Seok Han),전주원(Joo Won Chun),전성우(Sung Woo Jeon),백승화(Seung Hwa Back) 대한약학회 2005 약학회지 Vol.49 No.5

The inhibitory effect of ferulic acid and related phenolic compounds on the growth of normal cell lines and cancer cell line was evaluated by the MTT methods. Ferulic acid decreased the cell viability of human skin melanoma cells by the MTT method and the cell adhesion activity of human oral epithelioid carcinoma cells by the XTT method. These results suggest that ferulic acid has a potential anticancer activity.

건강검진자에서 담낭 담석의 유병률과 위험인자

정윤진 ( Yun Jin Chung ),박영대 ( Young Dae Park ),이호철 ( Ho Chul Lee ),조한진 ( Han Jin Cho ),박관식 ( Kwan Sik Park ),서은희 ( Eun Hee Seo ),전성우 ( Seung Woo Jeon ),조창민 ( Chang Min Cho ),탁원영 ( Won Young Tak ),권영오 ( 대한내과학회 2007 대한내과학회지 Vol.72 No.5

목적: 담석은 담도계의 가장 흔한 질환으로서 최근 우리나라에서 콜레스테롤 담석의 비율이 증가하고 있으며 그 대표적인 위험인자로는 연령, 여성, 비만 등이 거론되고 있다. 본 연구는 건강검진자를 대상으로 최근 7년간의 담낭 담석의 연도별 유병률 및 위험인자를 알아보고자 하였다. 방법: 1997년부터 2004년까지 경북대학교 병원 건강검진센터를 방문한 36,314명을 대상으로 키와 몸무게를 측정하고 공복 혈당과 간기능 및 기본 지질 검사를 하였고 초음파 검사를 통해 담낭 담석을 진단하였다. 체질량 지수에 따라 저체중, 정상체중, 과다체중, 비만 집단으로 나누었고, 공복 혈당 수치는 미국 당뇨 협회에서 제시한 당뇨병의 진단 기준에 따라 분류하였고, 간기능 수치는 본원에서 사용하는 간기능 정상치를 참조하여 대상군을 나누었다. 지질 수치는 NCEP ATP III에 따라 분류하였다. 결과: 36,314명의 대상자 중 남자는 19,345명, 여자는 16,969명이었고, 이 중 40대과 50대가 대상자의 50% 이상을 차지하였다. 담석이 발견된 경우는 735명(2.0%)으로 이 중 남자는 387명(2.0%), 여자는 348명(2.1%)로 유병률에 있어서 성별간 의미있는 차이는 없었다. 연도별 유병률은 1998년 1.9%, 1999년 1.6%, 2000년 1.4%, 2001년 1.7%, 2002년 1.6%, 2003년 2.8% 그리고 2004년에는 2.7%였다. 단변량 분석을 시행한 결과, 연령, 체질량 지수, 공복 혈당, 총 콜레스테롤, LDL-콜레스테롤, 중성 지 방, AST가 담석의 유병률과 의미있는 상관관계를 보였다. 다중 로지스틱 회귀 분석에서 체질량 지수, 연령, 공복 혈당이 담석증의 독립적인 위험인자로 선정되었다. 결론: 건강검진자를 대상으로 한 담낭 담석의 위험인자로는 높은 체질량 지수, 연령의 증가, 높은 공복 혈당으로 나타났다. 각각의 위험인자는 서로 개별적이라기보다 담석에 대한 공통 병인을 가지고 있으며, 담낭 담석이 대사 증후군과 관련되어 있을 가능성이 크다고 생각되나, 이를 규명하기 위해서는 앞으로 일반 인구를 대상으로 한 추가적인 연구가 필요하겠다. Background: Gallstone is the most common disease of the biliary system. Most cases of gallstone are asymptomatic and we incidentally found gallstones during a community health survey. Our study was designed to determine the prevalence and risk factors for gallstone in a population who underwent health screening. Methods: We enrolled a total of 36,314 persons who visited the health promotion center in Kyungpook National University Hospital in Korea from 1998 to 2004. They had their gallbladder or biliary system examined with using ultrasonography. The body mass index and biochemical parameters from liver function tests, the lipid profiles and the fasting blood sugar were all measured. All the subjects were divided into several groups and the particular prevalence for gallstone disease for each group was calculated. Chi-square tests and logistic regression analysis assessed the risk factors for gallstone disease. Results: Among 36,314 persons, (19,345 males (53.3%) and 16,969 females (46.7%)), gallstone was found in 735 persons (2.0%). On univariate analysis, the risk factors for gallstone disease were age, body mass index, fasting blood sugar, total cholesterol, LDL-cholesterol, triglyceride and serum aspartate aminotransferase. On multivariate logistic regression analysis, the risk factors were high body mass index, older age and high fasting blood sugar. Conclusions: The risk factors seem to show a common pathogenesis for gallstone disease. Although the relation between gallstone disease and metabolic syndrome has not been established, it appears to be associated with metabolic syndrome, but further study on a general population is required. (Korean J Med 72:480-490, 2007)

재발성 하부 위장관 출혈상을 보인 소장의 Mantle Cell Lymphoma 1 예

김성국,조재현,정준모,최용환,전성우,조창민,권영오,탁원영,배한익,하승수 대한소화기내시경학회 2000 Clinical Endoscopy Vol.20 No.4

Lower gastrointestinal bleeding is difficult to localize despite advanced diagnostic procedures such as colonoscopy, small bowel series, mesenteric angiography and radionuclide scan. We had experienced a case of mantle cell lymphoma of small bowel. In this case, the cause of recurrent lower gastrointestinal bleeding and abdominal pain was not defined despite extensive preoperative evaluation. We diagnosed this case as mantle cell lymphoma after exploratory laparotomy.

기능성 소화불량 환자에서 Helicobacter pylori 감염과 위배출능의 상관관계

김성국,이영두,최용환,정준모,전성우,이승엽,권영오,금민수,탁원영 대한소화기학회 2000 대한소화기학회지 Vol.35 No.6

Background/Aims: The aim of this study was to investigate the effect of Helicobacter pylori (H. Pylori) infection on individual dyspeptic symptoms and parameters of gastric emptying rate in patients with functional dyspepsia. Methods: The thirty-two patients with functional dyspepsia were included in the study. The patients were divided into two groups (H. pylori-positive group and H. pylori-negative group). For the patients of both groups, eight symptoms of dyspepsia were scored to obtain an index of dyspepsia, and gastric emptying of a solid meal were studied. Results: Half gastric emptying time (t½) was 84.2±31.0 min in H. pylori positive group and 82.2±26.9 min in H. pylori-negative group. There was no correlation between gastric emptying and H. pylori infection. In comparison of dyspeptic subtype (ulcer like dyspepsia, dysmotility like dyspepsia, mixed type), symptom severity (2.6±0.6 vs 2.4±0.7, P=0.28), and dyspeptic index (2.6±1.2 vs 3.0±1.6, P=0.4), there was no difference between the patientsnd without H. pylori infection. Moreover, individual dyspeptic symptoms except vomiting are not correlated with gastric emptying time. Conclusions: We believe that H. pylori infection does not affect gastric emptying and any individual symptoms of patients with functional dyspepsia.

미만성 간질환 진단에 있어서 초음파 유도하 간침생검의 정확도 : 수술 후 간조직과의 비교

김성국,박재홍,정준모,이영두,김대현,하승수,최용환,전성우,이승엽,권영오,탁원영,김동자,배한익 대한간학회 2000 Clinical and Molecular Hepatology(대한간학회지) Vol.6 No.3

$quot;목적: 초음파 유도하 간침생검은 합병증이 적으며 비교적 쉽게 시행할 수 있어 오늘날 간질환의 진단에 널리 이용되는 진단방법이다. 그러나 간침생검을 통하여 얻어진 간조직은 전체 간조직의 극히 일부분으로서 미만성 간질환인 간경변증과 같은 질병의 진단에 있어서는 보고자마다 상당한 진단율의 차이를 보인다. 이에 저자들은 초음파 유도하 간침생검과 수술 후 간조직의 병리조직학적 소견을 비교분석하여 간침생검의 정확도를 알아보았다. 대상과 방법: 초음파 유도하 간침생검을 통해 간세포암으로 진단받은 40예를 대상으로 배경 간조직생검을 동시에 시행하였고 이후 수술을 통해 얻어진 조직의 병리조직학적 진단의 일치율을 비교하였다. 조직학적 진단이 일치한 만성간염 6예에서 stage와 grade로 나누어 염증 및 섬유화의 정도에 대한 일치율을 비교하였고 아울러 초음파 유도하 간침생검을 통해 얻은 조직의 크기, 문맥구역수, 원인에 따른 일치율도 알아보았다. 결과: 초음파 유도하 간침생검과 수술 후 간조직의 조직학적 진단의 일치율은 75.0%였으며 원인에 따른 진단율의 차이는 없었으나 조직의 평균 크기는 조직학적 일치율을 보인 30예의 경우 1.87±0.10 cm, 불일치를 보인 10 조직학적 진단별 정확도는 간경변 20예 중 20예(100%), 만성간염 14예 중 6예(42.8%), 정상조직 6예 중 4예(66.7%)였다. 결론: 초음파 유도하 간침생검은 전체 간조직소견을 대변하는 비교적 정확한 검사방법으로 생각되나 간경변증이 있는 경우에는 실제 조직소견보다 경하게 나타날 수 있으므로 정확한 판독을 위해서는 적어도 4개이상의 문맥구역이 채취되어야 할 것으로 생각한다. 아울러 조직의 파편을 최소화 하여 진단의 위음성률을 줄이고 조직학적 진단과 임상적 진단이 일치하지 않는 경우, 조직의 파편이 심하거나 문맥구역이 4개 미만인 경우에는 반복적 생검 혹은 복강경하 생검 등 보다 적극적인 진단이 필요할 것으로 생각한다. $quot;Background/Aims: It is questionable whether the needle biopsy of the liver can represent the whole pathology of the liver. This study evaluates the diagnostic accuracy of ultrasonography-guided needle biopsy of the liver as determined by surgically resected liver. Method: The histopathologic findings of preoperative ultrasonography-guided needle biopsy for confirming the background liver disease and surgically resected liver were compared in the 40 patients with primary hepatocellular carcinoma. Results: 1) Of the 40 cases, 30 (75.0%) cases showed the same histopathological diagnosis between the two methods. Their histopathological results were: 20 cases of cirhosis, 6 cases of chronic hepatitis and 4 cases of normal tissue.2) There was a direct proportion between histologic concordance, the number of portal areas, and the size of the needle biopsy specimen. The histologic concordance rate was 79.2% in the cases with 4 portal areas in their biopsy sample and 100% in the cases with more than 5 areas. 3) Of the 10 cases in which diagnostic discrepancy was found between the two methods, 8 cases of chronic hepatitis and 1 case of normal tissue, all diagnosed by needle biopsy, proved to be cirrhosis by surgically resected liver. One case of normal tissue proved to be chronic hepatitis. The causes of diagnostic error were fragmentations of tissue and inadequate specimens. Conclusion: The diagnostic accuracy of the ultrasonography-guided needle biopsy of the liver was 75.0% in our study. To lessen the diagnostic error, at least 4 or more portal areas should be contained in the biopsy sample and the fragmentation of tissue should be minimized$quot;.

원발성 간암 환자에서 간동맥 색전술 시행 후 위십이지장 병변의 발생과 관련된 인자

김성국,조재현,정준모,최정일,최용환,전성우,권영오,탁원영,김용주,하승수,염헌규 대한소화기내시경학회 2000 Clinical Endoscopy Vol.20 No.3

Background/Aims: Gastroduodenal lesions such as erosions and ulcers are less infrequent complications after transcatheter arterial embolization (TAE) procedures. This study was conducted to clarify the incidence and associated factors of post-TAE gastroduodenal lesions. Methods: Cases involving 142 patients with unresectable hepatocellular carcinoma (HCC) who underwent TAE during 70 months were retrospectively analyzed. Endoscopic examinations were performed before and after TAE. Patients were classified into two groups depending upon whether gastroduodenal lesions developed or not. Results: New gastroduodenal lesions developed in 32 of 142 patients (22.5%) within 3 months of TAE. Of these, 14 patients (9.9%) developed upper gastrointestinal bleeding. There were no significant differences in clinical and biochemical characteristics between the two groups (p>0.05). There was also no significant difference in catheter selection level, tumor type, number of TAE, use of gelform between the two groups (p>0.05). wever, the cases involving large tumor size (>8 cm) and angiographical abnormalities of hepatic arteries including atypical branching, vascular tortuosity, spasms or intimal dissection during the procedure, infusion of embolizing materials adjacent to vessels supplying the stomach or duodenum, had more post-TAE gastroduodenal lesions. These two factors were found to significantly affect the development of post-TAE gastroduodenal lesions by multivariate analysis (p<0.05). Conclusions: The major factors associated with the development of post-TAE gastroduodenal lesions are large tumor sizes and angiographical abnormalities of hepatic arteries. Upper gastrointestinal endoscopy should be performed as follow-up examinations in these patients.