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이민기,신영기,박순규,허재영,도창호,조군제,임홍섭,문원국,최장락,이헌직 대한내과학회 1990 대한내과학회지 Vol.39 No.2
Tuberculous osteitis of the skull is an uncommon condition, first reported by Reid of Erlangen, who described two cases in 1842. By 1933. only 220 cases had been recorded in world literature (Strauss). It occurs in approximately 1%. of all patients with tuberculous osteitis and is diagnosed by clinical manifestation, skull roentgenogram, smear and culture of aspirated pus, and biopsy of granulation material. It responds readily to chemotherapy and the prognosis is favorable. To the best of our knowledge, the condition has not been previously reported in Korea. But recently we experienced a case of tuberculous osteitis of the skull in an 18-year-old male patient who complained of dyspnea, chest pain, multiple swelling of scalp and right eye proptosis. The patient was treated with antituberculous medication and discharged with his condition improved.
이민기 國立 昌原大學校 産業技術硏究所 1993 産技硏論文集 Vol.7 No.-
This paper presents the design of a high stiff robot arm. The robot is specially designed for removing riser and the bur of casting. In the casting process, the riser and the bur generated around the casing They must be removed by grinding, cutting, and milling. These machining works are defined as the fettling which creates an unpleasant environment due to lots of noise and dust. Therefore, the fettling needs the robot which automatically d you the machining works. The robot must have the special specification, which is a high stiffiness. This specification can not be satisfied by a common industrial robot. The arm structure causes a large deflection a high stiff robot arm. Several links support a robot gripper so strongly that it increase the stiffiness.
UPLC-DAD-QToF/MS를 이용한 야콘(Smallanthus sonchifolius) 괴근 내 페놀산 유도체 분석
이민기,김헌웅,이선혜,Gelila Asamenew,김영진,이수지,정현아,유선미,김정봉 한국식품영양과학회 2018 한국식품영양과학회지 Vol.47 No.12
The reported/proposed positive ion fragmentation of phenolic acid derivatives in yacon (Smallanthus sonchifolius) were summarized in the constructed LC-MS library for identification based on the literature. A total of fifteen phenolic acid derivatives (fourteen caffeoyl derivatives and one p-coumaroyl derivative) were separated and identified from the tuberous roots of yacon using UPLC-DAD-QToF/MS. Each caffeoyl derivative was conjugated with altraric acid, quinic acid, and octulosonic acid. The total content of each caffeoyl derivative was as follows: caffeoylaltraric acids (1,218.4 mg/100 g dry weight)> caffeoylquinic acids (331.5)> caffeoyloctulosonic acids (125.2). In particular, 2,3,5- or 2,4,5-tri-O-caffeoylaltraric acid (63% of the total phenolic acid derivatives) showed the highest contents followed by 5-O-caffeoylquinic acid (chlorogenic acid, 14%). Moreover, 2,3,5- or 2,4,5-tri-O-caffeoylaltraric acid methyl ester and 5-O-p-coumaroylquinic acid as new phenolic acid derivatives in yacon were identified putatively by the mass spectral data. This indicates that the individual phenolic acid derivatives in yacon might be determined easily using the constructed LC-MS library. Furthermore, it can provide valuable information for future studies on the health-promoting properties of yacon. 본 연구에서는 야콘에 보고된 페놀산 유도체의 라이브러리를 제작하고 이를 바탕으로 ToF/MS를 통해 검출된 양이온 질량 패턴을 비교하여 개별 페놀산 유도체의 조성 및 함량 정보를 제공하고자 하였다. 국내에서 재배된 괴근으로부터 caffeoyl 유도체(14종)와 coumaroyl acid 유도체(1종)를 분리・동정하였다. 개별 유도체는 caffeic acid와 altraric acid, quinic acid, octulosonic acid가 결합된 형태로 존재하였으며, 모분자로부터 제거된 caffeic acid의 단편 이온 패턴을 나타내었다. 각 유도체의 총 함량은 caffeoylaltraric acid 유도체 > caffeoylquinic acid 유도체 > caffeoyloctulosonic acid 유도체 순으로 높았다. 이 중 2,3,5- 또는 2,4, 5-tri-O-caffeoylaltraric acid 및 chlorogenic acid는 각각 총 함량의 약 63%, 14%로 괴근의 주요 성분이었다. 또한 이미 보고된 페놀산 유도체 이외에 2,3,5- 또는 2,4,5-tri- O-caffeoylaltraric acid methyl ester와 5-O-p-coumaroylquinic acid가 확인되었으며, 이는 야콘에서 보고된 적 없는 새로운 화합물이었다. 그러나 입체 배열에 따라 다양한 이성질체가 존재하는 caffeoylaltraric acid 유도체는 다양한 분석 기법을 통해 보다 정확한 동정이 필요할 것이다. 야콘 라이브러리에 수록된 페놀산 유도체 정보는 향후 정확한 구조 동정 및 함량 평가를 돕고 나아가 기능성 소재로서의 활용 가능성을 높일 수 있을 것으로 판단된다.
난포기 및 황체기에 있어서 돼지 난관협부 평활근의 자율적 운동성에 대한 Estradiol-l7$\beta$및 Progesterone의 영향
이민기,손동수,이영락,남정우,김주헌,최상용,Lee Min-Gi,Son Dong-Soo,Lee Yeong-Lak,Nam Jeong-Woo,Kim Joo-Heon,Choe Sang-Yong 한국임상수의학회 1991 한국임상수의학회지 Vol.8 No.2
The effects of estradiol-17$\beta$ and progesterone on the spontaneous motility of pig oviductal isthmic smooth muscle were investigated. The motility of the Isolated smooth muscle was recorded by using physiological recording system. The results were summarized as follows; 1. The amplitude and frequency of spontaneous motility in pig isthmic smooth muscle were 0.251$\pm$0.023 g and 15.380$\pm$0.935/min in follicular stage, and 0.201$\pm$0.027g and 14.520$\pm$1.382/min in luteal stage. 2. The spontaneous motility of pig isthmic smooth muscle was excited by estradiol-17$\beta$ but was not by progesterone in follicular and luteal stage.
이민기,반유정,이주호,이하영,이영동,권용구 한국고분자학회 2020 Macromolecular Research Vol.28 No.13
Hollow mesoporous carbon nanospheres doped with fluorine (FHMC) were synthesized for high-performance supercapacitor applications. Monodisperse nanospheres with a copolymeric core-silica shell were produced by charge density matching. The copolymeric chains in the core phase were crosslinked through a Friedel-Crafts reaction, followed by carbonization at 800 oC under a N2 atmosphere to obtain the core-shell (CSC) nanospheres with a carbon core and silica/carbon composite shell. The silica phase of these core-shell nanospheres was etched selectively during the thermal decomposition of Teflon to synthesize the FHMC nanospheres. During the etching process of silica in the shell phase, the surfaces of the nanospheres were doped with fluorine. The BET surface area was increased significantly from 788 m2/g and 1.31 cm3/g for the CSC nanospheres to 1021 m2/g and 2.55 cm3/g for the FHMC nanospheres. The specific capacitance of the FHMC nanospheres prepared was approximately 174 F/g at a current density of 0.5 A/g. The capacity retention after 10000 charge/discharge cycles at a current density of 1 A/g was approximately 93.6%.
Rare Intramedullary Myeloid Sarcoma Mistaken as Acute Transverse Myelitis
이민기,허정우,Ahn Stephen 대한말초신경학회 2018 The Nerve Vol.4 No.2
Myeloid sarcoma is a rare extramedullary tumor of immature myeloid cells. It more often develops with the underlying acute myeloid leukemia, but it can also occur with chronic myeloid leukemia (CML), myelodysplastic syndrome and rarely even with the absence of marrow involvement. Spinal epidural myeloid sarcoma is uncommon, and intramedullary presentation is exceptionally rare. In this report the authors report an unusual case of spinal intramedullary myeloid sarcoma after completer remission from CML several years ago. He was mistakenly diagnosed as acute transverse myelitis and treated with high-dose steroid and plasmaparesis without improvement. Magnetic resonance imaging revealed intramedullary mass-like lesion with hyper-intensity in T2-weighted image and mild homogeneous enhancement. Myeloid sarcoma should be considered as a possible differential diagnosis when patient with history of myeloid leukemia present intramedullary tumor and pathologic confirmation with open biopsy is mandatory for the exact diagnosis.