귀밑샘의 기무라병의 세침흡인 세포학적 소견 -세포학적 검사로 예측할 수 없었던 1예 보고-

김세훈,김혜령,김성은,양우익,이광길,홍순원,Kim, Se-Hoon,Kim, Hae-Ryoung,Kim, Sung-Eun,Yang, Woo-Ick,Lee, Kwang-Gil,Hong, Soon-Won 대한세포병리학회 2003 대한세포병리학회지 Vol.14 No.2

Kimura's disease is a chronic inflammatory disorder of unknown cause and is most prevalent among Asians. The cytologic findings of Kimura's disease are significant numbers of eosinophils in a background of lymphoid cells, occasional fragments of collagenous tissue, proliferation oi vessels, and Warthin-Finkeldey polykaryocytes. Among these features, the most important cytologic feature of Kimura's disease is a significant numbers of eosinophils. We experienced a case of Kimura's disease in the parotid gland which we fatted to recognize on cytology due to the apparent paucity of eosinophils. On careful retrograde reviewing of the cytologic findings, a few scattered leukocytes, previously interpreted as polymorphous leukocytes, had bilobed nuclei and coarse green but granular cytoplasm on Papanicolaou preparation. These leukocytes showed obvious orange-red intracyloplasmic granules as in eosionophils on Giemsa stain. The paucity of eosinophils may be due to the thick fibrosis around lymphoid follicles or any technical error during aspiration. Whereas the Warthin-Finkeldey type giant cell is not a sensitive cytologic marker of Kimura's disease, it may be a helpful cytologic feature. To reach a correct cytologic diagnosis of Kimura's disease, It is important to keep in mind that searching for Warthin-Finkeldey type giant cells and evaluation of Giemsa stain for detection of eosinophils would be helpful.

초미세 결정립을 가지는 몰리브덴의 제조 및 기계적 특성

김세훈,서영익,김대건,석명진,김영도,Kim, Se-Hoon,Seo, Young-Ik,Kim, Dae-Gun,Suk, Myung-Jin,Kim, Young-Do 한국분말야금학회 2010 한국분말재료학회지 (KPMI) Vol.17 No.3

Mo nanopowder was synthesized by ball-milling and subsequent hydrogen-reduction of $MoO_3$ powder. To fabricate ultra fine grained molybdenum, two-step sintering and spark plasma sintering process were employed. The grain size of specimen by two-step sintering and spark plasma sintering was around $0.6\;{\mu}m$ and $0.4\;{\mu}m$, respectively. Mechanical properties of ultra fine grained Mo with relative density of above 90% were significantly improved at room and high temperatures comparing to commercial bulk Mo of 99% relative density. This result was mainly explained by the grain size refinement due to diffusion-controlled sintering.

Nd-Fe-B 소결 자석의 보자력 향상

김세훈,김진우,변종민,김영도,Kim, Se Hoon,Kim, Jin Woo,Byun, Jong Min,Kim, Young Do 한국분말야금학회 2015 한국분말재료학회지 (KPMI) Vol.22 No.1

반복 열처리한 Nd-Fe-B 소결 자석의 미세구조 제어 및 자성특성 평가

김세훈,김훈섭,김동환,김영도,Kim, Se-Hoon,Kim, Hoon-Sup,Kim, Dong-Hwan,Kim, Young-Do 한국분말야금학회 2008 한국분말재료학회지 (KPMI) Vol.15 No.6

Sintered Nd-Fe-B magnets have been widely used due to their excellent magnetic properties, especially for driving motors of hybrid and electric vehicles. The microstructure of Nd-Fe-B magnets strongly affects their magnetic properties, in particular the coercivity. Therefore, a post-sintering process like heat-treatment is required for improving the magnetic properties of Nd-Fe-B sintered magnets. In this study, cyclic heat treatment was performed at temperatures between $350^{\circ}C$ and $450^{\circ}C$ up to 16 cycles in order to control microstructures such as size and shape of the Nd-rich phase without grain growth of the $Nd_{2}Fe_{14}B$ phase. The 2 cycles specimen at this temperature range showed more homogeneous microstructure which leads to higher coercivity of 35 kOe than as-sintered one.

(Nd, Dy)-Fe-B 분말의 소결특성 및 상변화 연구

김세훈,김진우,김영도,Kim, Se-Hoon,Kim, Jin-Woo,Kim, Young-Do 한국분말야금학회 2010 한국분말재료학회지 (KPMI) Vol.17 No.2

In this study, the sintering behavior of (Nd, Dy)-Fe-B powder which fabricated by strip-casting was investigated with various sintering temperatures and holding times. The relative density over 99% could be obtained by both sintering at $1070^{\circ}C$ for 1h and sintering at $970^{\circ}C$ for 20h. The grain growth was observed in sintered specimen at $1050^{\circ}C$ compared to one at $970^{\circ}C$. The isothermal sintering process below $1000^{\circ}C$ led to suppress grain growth showing the improved magnetic properties. The phase transformation of Nd-rich was confirmed by X-ray diffraction pattern.

진공사출금형용 STS316L 금속 다공체 제조 및 기계적 특성

김세훈,김상민,노상호,김진평,신재혁,성시영,진광진,김태안,Kim, Se Hoon,Kim, Sang Min,Noh, Sang Ho,Kim, Jin Pyeong,Shin, Jae Hyuck,Sung, Si-Young,Jin, Jin Kwang,Kim, Taean 한국분말야금학회 2015 한국분말재료학회지 (KPMI) Vol.22 No.3

In this study, porous stainless steel (STS316L) sintered body was fabricated by powder metallurgy method and its properties such as porosity, compressive yield strength, hardness, and permeability were evaluated. 67.5Fe-17Cr- 13Ni-2.5Mo (wt%) powder was produced by a water atomization. The atomized powder was classified into size with under $45{\mu}m$ and over $180{\mu}m$, and then they were compacted with various pressures and sintered at $1210^{\circ}C$ for 1 h in a vacuum atmosphere. The porosities of sintered bodies could be obtained in range of 20~53% by controlling the compaction pressure. Compressive yield strength and hardness were achieved up to 268 MPa and 94 Shore D, respectively. Air permeability was obtained up to $79l/min{\cdot}cm^2$. As a result, mechanical properties and air permeability of the optimized porous body having a porosity of 25~40% were very superior to that of Al alloy.

골반골의 악성 골종양의 재건술에서 체외 열처리를 이용한 재활용 자가골 이식술 및 인공 관절 치환술을 시행한 3례 보고

김세훈,이상훈,조환성,김한수,Kim, Sae-Hoon,Lee, Sang-Hoon,Cho, Hwan-Sung,Kim, Han-Soo 대한근골격종양학회 2003 대한골관절종양학회지 Vol.9 No.1

연구계획: 골반골의 악성골종양의 재건술에서 체외열처리를 이용한 재활용 자가골 이식술 및 인공 관절 치환술을 시행한 3례의 후향적 연구 연구목적: 골반골의 악성골종양의 재건술에서 체외열처리를 이용한 재활용 자가골 이식술 및 인공 관절 치환술이 골반골의 재건에 있어 그 유용성을 알아보고자 하였다. 증례: 증 례 1~20세 여자 환자로 3개월 전부터 시작된 우측 고관절부와 대퇴부 동통을 주소로 외부 병원에서 우측 장골에 소파술 및 골 시멘트 충전술 시행 후 악성 골종양으로 진단하에 술 후 방사선 치료 6회 시행 후 전원되어 우측 장골 광범위 절제술 및 섭씨 132도에서 2분간 열처리 후 자가골 재삽입술 시행하고 우측 고관절의 인공 관절 치환술 (ABG$^{(R)}$)을 병행하였다. 수술 당시 전이의 증거는 없었으며 술후 조직 병리 검사상 고분화 골육종 진단되었으며 술전 또는 술후 화학 요법은 시행하지 않았다. 증 례2~56세 여자 환자로 약 3개월 전부터 시작된 우측 대퇴부 동통으로 방사선 검사상 이상 발견되어 전원 후 절개 생검 시행하였다. 결과상 골육종 진단되어 우측 골반골 광범위 절제술 후 섭씨 6 5도 하에서 3 0분간 저온 열처리 후 자가골 삽입 고정술 시행하고 우측 고관절에 대하여 인공 관절 치환술 (ABG$^{(R)}$)을 병행하였다. 수술 당시 전이의 증거는 없었으며 술 후 조직 병리 검사상 고등급 섬유모세포형의 골육종이 진단되었다. 술후 화학 요법은 HDMTX, ADR, CDDP으로 시행하였다. 증 례 3~46세 여자 환자로 우연히 발견된 좌측 장골의 종괴로 연골육종 의심 하에 좌측 골반골 광범위 절제술 후 섭씨 65도 하에서 30분간 저온 열처리 후 자가골 삽입 고정술 시행하고 좌측 고관절에 대하여 인공 관절 치환술 (Protek$^{(R)}$)을 병행하였다. 수술 당시 전이의 증거는 없었으며 술후 조직 병리 검사상 II/III 등급의 연골육종이 진단되었다. 결과: 최종 추시상 각 증례의 종양학적 및 기능적 결과는 증례 1은 7년 추시상 국소적 재발이 없는 상태였으며 Ennecking 등에 따른 기능적 평가 지수에서 53%로 평가되었다. 방사선 추시상 약 1년에서 1년 6개월 사이에 골유합이 관찰되었으며 최종 추시시 장골의 재건 금속판의 파괴 소견이 보였으나 환자의 증상과 연관되지는 않았다. 증례 2는 3년 6개월 추시상 국소적 및 원격 재발이 없는 상태였으며 기능적 평가 지수는 60%로 평가되었다. 증례 3은 7개월 추시상 국소적 및 원격 재발이 없는 상태였으며 기능적 평가 지수는 63%로 평가되었다. 결론: 체외 열처리를 이용한 재활용 자가골 이식술 및 인공 관절 치환술을 시행한 3례에서 비교적 만족할만한 종양학적 및 기능적 결과를 보였으며 한국에서 동종 골 이식술이 어려운 점을 감안할 때 이 방법은 골반골을 재건하는데 한 방법이 될 수 있을 것이라 사료된다. Study Design: A retrospective clinical and radiographic review. Objectives: The purpose of this study was to suggest recycling bone autotransplantation with extracorporeal heat-treatment as one of favorable reconstruction method for malignant bone tumors of pelvis through 3 cases. Summary of Literature Review: There are many biologic and nonbiologic reconstruction method in pelvic reconstruction. Cases: Case 1- A 20-year-old women had chief complaint of right hip and thigh pain started 3 months ago and done curettage and bone cementing at right ilium at other hospital. She had impression of malignant bone tumor and undergone postoperative radiation therapy for 6 cycles. After that she was referred to our hospital and undergone wide excision of right ilium and recycling bone autotransplantation with extracorporeal heat-treatment at 132 degree celsius for 2 minutes internal fixation with pelvic reconstruction plate and total hip replacement arthroplasty (ABG$^{(R)}$). There was no evidence of distant metastasis and revealed well-differentiated osteosarcoma on postoperative pathology. Neither adjuvant nor neoadjuvant chemotherapy were done. Case 2- A 56-year-old women who suffered right thigh pain for 3 months was detected radiologic abnormality at right pelvis. After incisional biopsy, osteosarcoma was diagnosed. We had undergone wide excision of right ilium and recycling bone autotransplantation with extracorporeal low heat-treatment at 65 degree celsius for 30minutes internal fixation with pelvic reconstruction plate and total hip replacement arthroplasty (ABG$^{(R)}$). There was no evidence of distant metastasis and revealed high-grade osteosacoma which was fibroblastic type on postoperative pathology. Adjuvant chemotherapy (HDMTX, ADR, CDDP) was done immediate after wound healing was completed. Case 3- A 46-year-old women was incidently found mass at left ilium which was suspected chondrosarcoma. We had undergone wide excision of left ilium and recycling bone autotransplantation with extracorporeal low heat-treatment at 65 degree celsius for 30minutes internal fixation with pelvic reconstruction plate and total hip replacement arthroplasty (Protek$^{(R)}$). There was no evidence of distant metastasis and revealed chondrosarcoma which was graded II/III on postoperative pathology. Results: Oncologic and functional outcome at final follow-up were for case 1, final follow-up time was 7 years, is no evidence of disease and functional score is 53% according to Ennecking et al. During follow-up, evidence of radiologic union was at about 1 and 6 months after operation. The case had breakage of pelvic reconstruction plate and some resorption of autotransplated bone, but no symptom present. For case 2, final follow-up was 3 years and 6 months, is no evidence of disease and functional score is 60%. For case 3, final follow-up was 7 months, no evidence of disease and functional score is 63% which is improving state. Discussion: 3 cases which were undergone recycling bone autotransplantation with extracorporeal heat-treatment and total hip replacement arthroplasty had relatively successful oncologic and functional outcome. Taking account that difficulty in using allograft in Korea this method is thoght to be one of the useful way to reconstruct pelvis after resection of primary malignant bone tumor of the pelvis.

수중운동이 뇌졸중 환자의 균형과 우울에 미치는 효과

김세훈,이동규,김은경,Kim, Se-Hun,Lee, Dong-Kyu,Kim, Eun-Kyung 대한물리치료학회 2014 대한물리치료학회지 Vol.26 No.2

Purpose: The purpose of this study was to understand the effect of aquatic exercise on balance and depression of stroke patients. Methods: For 12 participants with stroke, six members of the experimental group and six members of the control group were randomly selected and arranged. Proprioceptive Neuromuscular Facilitation (PNF) lower extremity aquatic pattern exercise was applied to the experimental group. On the other hand, participants in the control group performed PNF lower extremity pattern exercise on the ground. Both exercises were performed 30 minutes per day, five times per week, for a period of six weeks. Balance was assessed using the Berg Balance Scale (BBS) and Timed Up to Go test (TUG). Depression was measured using the Center for Epidemiologic Studies depression scale (CES-D). Results: As a result of comparison within groups, the experimental group showed significant difference for balance and depression after the experiment (p<0.05). In comparison between the two groups, the experimental group in which aquatic exercise was applied showed more significant change in balance and depression than the control group (p<0.05). Conclusion: According to the results of this study, aquatic exercise was proven to enhance the balance and decrease the depression of stroke patients.

Electroluminescence from the Evaporated Thin Film of Excited-state Intramolecular Proton Transfer Dye

김세훈,장동욱,박수영,김경곤,진정일,Kim, Se Hun,Jang, Dong Uk,Park, Su Yeong,Kim, Gyeong Gon,Jin, Jeong Il Korean Chemical Society 2001 Bulletin of the Korean Chemical Society Vol.22 No.12

한국 중소기업의 베트남 투자 분석: T사의 사례연구를 통하여

김세훈,Kim, Kyungmi,박현준 한국국제경영관리학회 2018 국제경영리뷰 Vol.22 No.4

Korea`s shoe industry has been steadily growing since the 1920s due to cheap and abundant labor. However, since the 1980s, exports and original equipment maker (OEM) orders started to decline because of Korea's rising labor costs and price competitiveness with Southeast Asian neighbors like China, Vietnam, and Indonesia. Therefore, domestic shoe factories, which have failed to overcome the high labor costs since 1980 had to move production bases to China, Vietnam, and Indonesia where labor costs are low. Thus, this research explored a Korean footwear company called the T company which is a renown shoe manufacturing company in South Korea. By analyzing the Export-Import Bank of Korea, Korea Trade-Investment Promotion Agency (KOTRA), Vietnam National Statistical Office, and Vietnam Foreign Investment Agency, the research was to understand and examine the T company’s business strategy overbroad, especially in Vietnam. We explored the accumulated investment-related issues and changes in the Vietnamese market and business environment. Furthermore, we investigated strategies and plans for how to cope with this change. We analyzed and examined the T company's ownership, location, and internalization advantages, as an example, which based on the eclectic paradigm and economic trends of the Vietnamese government and the state of the footwear industry. Finally, we investigated the future investment trends by sector and region to assist potential companies in entering the prospective Vietnamese market. 한국의 신발산업은 1920년대 이후 저렴한 인건비 및 풍부한 노동력에 의해 지속적으로 성장을 했다. 그러나 1980년대 이후 한국의 인건비 상승과 동남아시아의 주변국인 중국, 베트남, 인도네시아와 가격 경쟁력에서 차이를 보이게 됨으로써, original equipment manufacturer (OEM) 주문량이 줄어들기 시작하고 수출액 또한 감소세에 이르게 되었다. 따라서 1980년 이후 높은 인건비의 벽을 넘지 못한 국내 신발 공장들은 인건비가 저렴한 중국, 베트남, 인도네시아로 생산 기반을 이전하게 되었다. 이를 바탕으로 본 연구는 한국수출입은행, 대한무역투자진흥공사(KOTRA), 베트남 통계청, 베트남 외국인 투자 청과 국내 중견기업인 T사의 지속가능경영보고서를 기반으로 경공업 분야에서 베트남에 진출하고자 하는 국내 제조업 분야 중소기업의 투자방안에 대해 분석하였다. 또한 이 연구는 그동안의 축적되어온 투자 관련 이슈와 베트남 시장 및 기업 환경의 변화 등에 대해 자세히 기술하고 있고 이 변화에 어떻게 대처하는가에 대한 전략과 방안을 논의하였다. T사의 사례연구를 통하여 한국 신발산업의 사업 현황과 베트남 경제 동향 및 신발산업을 비교 분석하여 베트남 진출에 있어 T사의 성공사례를 기반으로 향후 베트남 투자에 진출하고자 하는 기업에 도움이 되고자 한다.