Carcinoma Showing Thymus-Like Differentiation (CASTLE)치험 1예

김진평,성병기,안성기,이정희 대한이비인후과학회 2004 대한이비인후과학회지 두경부외과학 Vol.47 No.5

Carcinoma showing tymus-like diferentiation (CASTLE)and surounding soft tisue, or soft tissue of the neck. It originates from ectopic thymus or branchial pouch remnants. The histolo-gic finding shows that the tumor is divided into lobules of variable size and shape, cord with thin and thick fibrous septa, which are infiltrated by lymphocytes and plasma cells. Tumor cells consist of large vesicular nuclei, prominent nucleoli, and abundant cyto-lymphoepithelioma of thymus. We report a case of CASTLE that we treated by surgery and radiation therapy.

미국의 타이포그라픽 디자인 교육에 관한 연구

김진평 서울여자대학교 조형연구소 1995 조형연구 Vol.1 No.-

In today's information industry it is no exaggeration to say that the level of quality in the visual communicative media would be heavily influenced by the development of the typographic field within their own cultural sphere. Despite the relatively early development of their unique printing technique, Korean contemporary typography lacks the kind of development as seen in other fields. University education appears to be one of the main reasons of this "underdevelopment" of contemporary typrography. Typographic course is normally not included in the university visual communication design or related curricula and this clearly demonstrate that universities do not appear to recognize the importance of typography. This paper is intended to look at the typography education in American universities which followed the Modern Typography Movement of the western world. Out of 249 universities which have design departments from [INDEX OF MAJORS 1989/90] 48 universities were initially selected with the assitance from a Professor at Syracuse University and asked to send their course catalogs and syllabi. 28 universities replied but the materials from 23 universities were proper to survey and analyzed as follows. Typographic courses are offered to students in the sophomore and junior year with very high specific gravity in the curricula of major American schools of visual communication design or graphic design. The average ratio of typographic courses to all the major courses in each year is 23.2% in the sophomore, 25.7% in the junior and 13.4% in the senior year. Typographic courses are divided into three groups of different name which are the ones of direct name, indirect name and inclusive name. The courses of direct name which there are "typography" or "typographic" on these names have genuine typographic contents. And the ones of indirect name related indirectly to typography such as "type design", "letterform" or publication design" and so on have more specified contents concerned with their names. On the contents in the courses of inclusive name as some courses as "basic graphic design" or "design skills and processes", typography is particulary stressed on as basic course of or as application one to graphic design and these can not be differentiated by their names but by their contents. Typographic courses are listed on the graphic design major curricula with relatively high importance as 20.8% as the average ratio which there are 12.5% of the courses of direct name, 5.6% of indirect name and 2.6% of inclusive name. In most of American schools, the average contents in the instruction of typographic courses are both the understanding and use of typography. Especially the emphasis is placed on the technical skills from the relating industry, like hand and photo composition and word, page processing computer software, printing, production and so on in typographic courses. For the understanding of typography, students are introduced to the terminology, history and technical aspects such as type specification and selection, type composition and computer software. For the use of typography, they are taught to technical approach, including proportion, grid, layout, printing process, and to communicative and expressive approach, like visual hierachy, typographic structure, the relation of typeface, legibility, readability and character recognition. Finally students are encouraged to find their own style and to develop the experimental typographic expression. Many American visual communication design or graphic design schools offer typographic instruction at the courses of direct or indirect name listed in their curricula of major. Although other schools do not list typographic courses, they certainly offer instruction related to typography even at the courses of inclusive name. It does appear as a result of this research that all the American schools recognize typography as one of the elements composing of visual communication design or graphic design, not as the independant area in that major, and with such recognition, they offer instruction in typography.

한글 활자체 변천의 사적 연구 : [특집 II] 한글 글자꼴 기초연구

김진평 한국출판연구소 1990 출판 연구 Vol.1 No.-

한글의 산업화와 글자꼴

김진평 국어연구소 1985 국어생활 Vol.- No.3

Quantitative Analysis of Myosin Heavy Chain Expression Change in Laryngeal Muscle after Irradiation in Rats

김진평,Roza Khalmuratova,전시영,박정제,허동구,안성기,우승훈,강기문,채규영 연세대학교의과대학 2011 Yonsei medical journal Vol.52 No.1

Purpose: Radiotherapy for head and neck cancer does not impair the voice quality as much as laser treatment or surgery, but it can induce muscle wasting and fibrosis and symptoms of dry mouth. We investigated the effect of irradiation on the myosin heavy chain (MyHC) expression in laryngeal muscles. Materials and Methods: Rats were irradiated with one dose of 10, 15, 20, 25, 30, or 35 Gy and other rats were irradiated with 20 Gy. The thyroarytenoid (TA), posterior cricoarytenoid (PCA), and cricothyroid (CT) muscles were subjected to reverse transcription-polymerase chain reaction (RT-PCR). Results: Two weeks after irradiation with 10, 15, or 20 Gy, all the MyHC type expressions had decreased in a dose-dependent manner in the TA, PCA, and CT muscles, and especially the expression of MyHC IIa decreased much more than the expressions of the other MyHC isoforms in all muscles. In the 20 Gy-irradiated rats, almost all the MyHC isoform expressions declined over 12 weeks in the TA, PCA, and CT muscles, except for the MyHC I expression in the PCA and CT muscle. The MyHC IIa expression was markedly decreased in all the muscles. Conclusion: The laryngeal muscles responded differently to radiation, but they showed a time-dependent and long-lasting decrease in the expressions of all the MyHC isoforms in the TA, PCA, and CT muscles. In particular,the expression of the MyHC IIa isoform in all the muscles may be more sensitive to irradiation than the expressions of the other MyHC isoforms.

Analysis of Clinical Feature and Management of Laryngeal Fracture: Recent 22 Case Review

김진평,우승훈,조상재,손희영,박정제 연세대학교의과대학 2012 Yonsei medical journal Vol.53 No.5

Purpose: Laryngeal fracture is rare, but complications are frequent and severe. Controversy still exists in regards to its proper management. The aim of this study was to present the clinical findings and management of laryngeal fracture in Korea. Materials and Methods: We analyzed the medical records of 22 patients with laryngeal fracture at a tertiary care trauma center from 2000 to 2010 retrospectively. Results: In total, 22 patients (19 men and 3 woman) presented with laryngeal fractures caused by blunt (n=13) or penetrating (n=9) injury. Pain (68.1%), odynophagia (68.1%), hoarseness (18.1%), hemoptysis (13.6%), and subcutaneous emphysema (9%) were the common presenting symptoms and noncomminuted fracture was common. High velocity blunt trauma (mostly traffic accidents) patients had more extensive injury and poor voice outcomes. Penetrating trauma patients due to physical assault or suicide attempt demonstrated more frequently injuries on the left side. Conclusion: In driver-caused traffic accidents, where injuries in a wide area within the larynx occurred, poor voice results were seen, and these injuries required aggressive treatment. When endotracheal intubation was performed at experienced emergency centers with fiberoptic laryngoscopes, airway management was safely achieved. In addition, if the fractured laryngeal framework was corrected at appropriate times, voice results were good.

Effectiveness of an i-PTH Measurement in Predicting Post Thyroidectomy Hypocalcemia: Prospective Controlled Study

김진평,박정제,손희영,김록범,김호엽,우승훈 연세대학교의과대학 2013 Yonsei medical journal Vol.54 No.3

Purpose: Hypocalcemia is the most common complication after total thyroidectomy. The purpose of this study was to determine whether measurement of intact parathyroid hormone (i-PTH) level in thyroidectomy patients could predict hypocalcemia. Materials and Methods: We performed a prospective study of patients undergoing total thyroidectomy. Serum concentration of i-PTH, total calcium (Ca), ionized calcium (Ca2+), phosphate (P), magnesium (Mg), and albumin were measured preoperatively and at 0 hour, 6 hours, 12 hours, 24 hours, 48 hours, and 72 hours postoperatively. Results: 108 patients were recruited to the study. A total of 50 patients (46%) experienced hypocalcemia. The serum i-PTH concentration was linearly related to the time of measurement, while concentrations of P, Mg, albumin,Ca, and Ca2+ were not. We compared odds ratios, and found that the concentration of i-PTH at 6 hours post operation was the most closely related to the occurrence of hypocalcemic symptom. On ROC analysis using i-PTH level at 6 hours, an i-PTH level of 10.6 mg/dL was found to maximize both sensitivity and specificity at the same time point. Conclusion: We found that i-PTH was a predictor of hypocalcemia,and that the earliest predictor of hypocalcemic symptoms was an i-PTH concentration lower than 10.6 mg/dL obtained 6 hours after total thyroidectomy.

한성주보 한글활자꼴에 관한 연구(1) : 타이포그라피 표현을 중심으로 With Emphasis on the Typographic Expression

김진평 서울여자대학교 조형연구소 1997 조형연구 Vol.3 No.-

비부비동염 흰쥐모델의 비 과민반응에 있어서 유도형 산화질소 합성효소의 역할

김진평,전시영,안성기,황원효,성병기,김은아 대한이비인후과학회 2003 대한이비인후과학회지 두경부외과학 Vol.46 No.1

Background and Objectives:Hyper-responsivenes to nonspecific stimuli is a characteristic finding of all allergic diseases. It the whole mechanism has not been clearly established. We aimed to understand the role of inducible nitric oxide synthase (iNOS) expresion in nasal hyper-responsivenes of rhinosinusitis. Materials and Method:1) To develop a platelet activating factor (PAF)-induced rhinosinusitis rat model, 50 μl of 16 μg/ml PAF was applied into the nose of rats. At days 1, 3 and 5, the rats were killed. 2) μl of 10 μM capsaicin was applied intranasaly and the amount of microvascular leakage in the nasal mucosa was measured with Evans blue asay at days 1, 3 and 5 in the rhinosinusitis model and the control rats. 3) To examine the efect of iNOS, 75 mg/kg of aminoguanidine was pretreated systemicaly 1 hour before the application of capsaicin. 4) To localize the expresion of iNOS, immunohistochemical staining was performed using the avidin-biotin-peroxidase method with an anti-iNOS antibody. Results:Induction of rhino-ium, varied according to the time interval, were observed. A significant enhancement of microvascular leakage was clearly demon-strated by topicaly applied capsaicin, which was completely blocked by aminoguanidine, the iNOS inhibitor in the PAF-induced rhinosinusitis. The expression of iNOS was localized in the inflamatory cells infiltrated in the mucosa. Conclusion:The expression of iNOS in the inflamatory cells as well as epithelial damage related to eosinophil infiltration may cause nasal hyper-responsivenes. (Korean J Otolaryngol 203 ;46 :35-41)

한글 활자체의 조합형 설계방법에 관한 연구

김진평 서울여자대학교 대학원 1994 論文集 Vol.- No.2