폴리우레탄의 상분리에 미치는 소프트-하드 세그먼트 농도의 영향

이현주,이상만,이상록,김광 동아대학교 공과대학부설 생산기술연구소 1998 生産技術硏究所硏究論文集 Vol.3 No.1

When we compared each reactivity of prepolymers during the reaction process, the mole ratio of [NCO]_T/[OH]_T which was evaluated effectively was 1.78. It was confirmed that effect of polyols was higher than that of isocyanates in comparison of reactivity according to the kinds of isocyanates and polyols. Segmented polyurethane also can be varied using the mole ratio of the polyol and the chain extender. The morphological changes induced to segmented polyurethane elastomers by varying the [NCO]_P/[OH]_P ratio during the second step of polymerization with MDI-polyether system, while keeping almost constant the total hard-segment content(∼70%) and that TDI-polysther system which was increased according to the[NCO]_P/[OH]_P ratio, were studied by means of differential scanning calorimetry(DSC).

`예외상태 상례화`로서의 유신헌법과 한국적 민주주의 담론

이상록 ( Lee Sang Rok ) 역사문제연구소 2016 역사문제연구 Vol.20 No.1

Restoration system is constantly emphasized the `sum` to configure the homogenization that `national` subjects. The core of the Restoration system was a system which encourages competition and end the crisis North Korea, it was composed in the form of economies war(經濟戰). Kim Il Sung`s only ruling bloc of the South felt a sense of urgency overlooking the ruling system, in order to win the economies around merrily under organization of national power, maximize efficiency, the flag of the `sum` for a self-help (自助) to be their labor Warriors It was required to `the people`. System was to require a `search machines` appeal under the leadership of President Park Chung-hee solar distraction of moving subjects to be `being the people`. Restoration system, basing such a rosy future, leaps and bounds growth of population livelihood as the national economy, the welfare state `80s achieved national culture` was the cry develpoment tried to secure national identity. Such efforts but also reap certain achievements, personal body on the train of industrialization in fact, state the desire of the public is constantly being difficult to differentiate and segment stitching iteotgie in the name of `the people`. Effects of consumption desires of the public and cultural needs of the industrial, social and were eager etc. for the rise is amplified, they are viewed from the banner of the `sum` `extravagant and decadent. Enjoyment. Corruption` things to be ruled out in the name of such It was. Oppression of OCD and 70 control of the ruling bloc`s ruling system configurations for homogeneous entity called `citizens` censorship surveillance. Were placed on the ground to strengthen the discipline Tuesday. Restoration regime ended by “personal domination” of the lies that were `Leader` Park on top with a 10.26 death, the state of exception was being continued in sovereign bonds of dictatorship and nationalism as `exceptions` and not `rules`.

마우스 대장암 모델 구축 및 항암제 활성 평가를 위한 예비 연구

김예솔,강봉석,이상은,이은주,이경록,정상헌,박정숙 충남대학교 약학대학 의약품개발연구소 2014 藥學論文集 Vol.29 No.-

Abstract – Aberrant crypt foci (ACF) are early imorphological changes observed in rodents after administration of colon-specific carcinogen such as azoxymethane (AOM). ACF are considered to be putative preneoplastic lesions and are widely used as a surrogate biomarker to rapidly evaluate chemopreventive potential of compounds. The size of colorectal cancer was evaluated after administration of three anticancer drugs, 1 parent drug and 2 prodrugs. The body weights of mice were measured daily and considered as a surrogate for evaluation of general wellbeing. Colons were removed, cut along the longitudinal axis and flushed with phosphate-buffered saline. Each colon was cut into three equal lengths and fixed flat between filter papers. The fixed colon sections were stained with methylene blue. The number of ACF per colon, the number of aberrant crypts observed in each focus and the location of each focus were recorded. After single administration of AOM and multiple doses of anticancer drugs, no significant changes in the body weights of the mice was observed which was recorded for 52 days. However, an expected ACF was not observed in any treated groups. These findings suggest the induction of ACF in mice requires the promotion by dextran sulfate sodium as well as the initiation by AOM.

건강한 한국인 성인 남성에서 레보설피리드 제제의 생체이용률

이정민,최성업,김희규,윤미경,김세희,염정록,최영욱 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.3

Pharmacokinetics and oral bioavailability of levosulpiride was determined in Korean healthy male volunteers. Thirty subjects received a single oral dose (25 ㎎) of a tablet in randomized 2×2 cross-over design. The plasma concentratons of levosulpiride were measured by HPLC and compared with those reported in the literature. Pharacokinetic parameters for Isomeric^(??) tablet (levosulpiride 25 ㎎) were revealed as follows: AUC _(inf) 737.1±176.9 ng·hr/ml, C_(max) 56.4±20.1 ng/ml, T_(max) 4.2±1.6hr, K_(a) 1.00±1.09 hr^(-1), K_(el) 0.08±0.02 hr^(-1), and t_(1/2) 8.8±1.9 hr. The rate constant of the absorption phase was obtained based on the first-order kinetics. In the aspect of bioavailability, Isomeric^(??) tablet was bioequivalent to the other product (Levopride^(?)tablet) available in the Korean market. Intersubject variations and race differences were shown in comparison with the published date in the literature, even though there ws a linear relationship between dose and extent of bioavailability.

성장기 흰쥐의 족삼리(ST-36) 침자가 혈액성분에 미치는 영향

이성동,윤범철,류정록,최태암 高麗大學校 倂設 保健大學 保健科學硏究所 2000 保健科學論集 Vol.26 No.1

Acupuncture, an important branch of oriental medicine, has been practiced for many centuries and has been proved to be an effective treatment for all sorts of disease. However, the exact mechanism on effects of acupuncture was uncertain. Recently investigation for the mechanism of acupuncture has concentrated to human and animals. So, This study was to determine effects of ST-36 acupuncture stimulation on blood component in growing rats. For this study, 24 male Sprague-Dawley rats weighting 159?13g were randomly assigned into three groups; A4 group, A10 group, and control group. In A4 group, four times acupuncture were performed at both ST-36 every other days and in A10 group, ten times acupuncture. The results obtained were as follows; 1. Total protein level was significantly increased, particularly in A10 group; albumin level was also significantly increased. 2. Serum glucose level was significantly increased. 3. Triglyceride level was significantly increased in A4 group; phospholipid level had no changes; free fatty acid level was significantly decreased particularly in A10 group. 4. Total cholesterol level was rarely affected by acupuncture: HDL-C and LDL-C levels were affected by the number of times of acupuncture, that is, HDL-C levels were increased, and LDL-C level decreased in A4 group, while HDL-C level decreased and LDL-C level increased in A10 group. 5. Serum amylase activity was not significantly changed.

자활사업에 대한 자활사업 참여자의 인식과 태도가 자활사업의 성과에 미치는 영향

이상록 서울대학교 한국사회복지연구회 2003 사회복지연구 Vol.21 No.-

본 연구에서는 복지제도에 대한 대상자의 태도와 복지제도 성과간의 관련성에 주목하여, "자활사업에 대한 자활사업 참여자의 인식과 태도는 어떠한지", 그리고 "이와 같은 인식과 태도들은 자활사업의 성과에 어떠한 영향을 미치는", "자활사업에 대한 태도의 차이에는 대상자들의 어떤 특성이 관련되어 있는지" 등을 규명하고자 하였다. 분석 결과에서는 자활사업 참여자들의 자활사업에 대한 인식과 태도는 자활사업에 대한 사회적 논란에도 불구하고 대체로 긍정적임을 확인할 수 있었다. 한편, 자활사업에 대한 태도가 자활사업의 성과에 미치는 영향을 분석한 결과에서는 태도의 주요한 영향을 확인할 수 있었는데, "자활사업에 대한 태도가 긍정적일수록 특히 자활사업의 효과에 대한 태도가 긍정적일수록 자활사업의 성과가 높다는 점을" 확인할 수 있었다. 한편, 자활사업에 대한 태도는 성별, 건강수준, 가구 부채액, 거주유형, 근로경력, 기술자격증, 정부 지원 프로그램에의 참여 경력, 자활사업 참여기간, 수급액수 등에 따라 유의미한 차이가 있음을 또한 검증할 수 있었다. 이상과 같은 본 연구의 분석결과는 자활사업의 성과 제고를 위해서는 자활사업에 대한 대상자의 인식과 태도 개선을 위한 적극적인 방안 모색이 필요하다는 점을 정책적 함의로 시사하여 주며, "복지제도의 성과와 복지제도에 대한 대상자들의 태도"간의 쌍방향적 규정성에 대한 새로운 주목이 필요함을 이론적 함의로 제기하여 준다. The purpose of this study is to identify the effects of welfare recipients' views and attitudes toward the self-support program on the program outcomes. Using the survey data from program participants. This paper identified their views and attitudes toward the program and evaluated effects of their views and attitudes on the program outcomes. Major Findings are as follows. First, regardless of political debates on the self-support program's effectiveness, welfare recipients' view and attitudes toward the program are positive in general. Second, I found that strong associations between view and attitudes toward the self-support program and program outcomes. From the results of OLS regression analyses, I found the significant effects of view and attitude variables on program outcomes. It means that the positive view and attitudes toward the program increase the positive outcome, that is the positive changes of the self-reliant attitudes, behaviros, and skills. Third, from the T-test and one-way ANOVA analysis results I found also that welfare recipients' view and attitudes are significantly different according to the sex, degree of physical health, labor market experiences, welfare reception experiences, family debts, duration time in the program, and cash benefit levels. Above these findings point to the strong evidence for the hypothesis that welfare recipient's view and attitudes toward the self-support program have a significant impact on program outcomes. And also, they suggest that the efforts to change welfare recipient's view and attitudes toward the self-support program have a significant impact on program outcomes. And also, they suggest that the efforts to change welfare recipient's view and attitudes toward the program are necessary to level up the effectiveness of the self-support program.

발열-흡열반응이 동시에 일어나는 화학반응장치의 안정성 해석

이상록,염치호,장상목,김광 동아대학교 공과대학부설 생산기술연구소 1997 生産技術硏究所硏究論文集 Vol.2 No.1

It was described that relationships between the shape of Y(T) and stability of steady state in a complete mixing type reactor in which exothemic and endothermic reactions were proceed simultaneously. These results could be obtained sufficient conditions to stable any steady state by making use of the linearization theorem. Sufficient conditions for p>0 is Y´(T)<0, for p>0, q>0 is Y´(T)<0 and Y(T)>0, where Y(T)= α_1k_1 (T)+ α_1k_1(T) and Y´(T)=dY(T) /dY(T).

알콜의 산화-탈수소 반응공정의 안전조작

이상록,여경희,최재욱,김상열 동아대학교 공과대학 부설 한국자원개발연구소 1994 硏究報告 Vol.18 No.2

The effect of the temperature and the concentration of the reactor inlet gas on the safe operation of a fixed-bed reactor for exothermic-endothermic Catalytic process is investigated. The important industrial process of vapour phase oxidation-dehydrogenation of methanol into formaldehyde is used as an example. The safe operation of steam addition, air/methanol ratio and feed temperature is performed to be outside the flammable region. And it is also essential to prevent the possible explosion.

梔子栢皮湯이 膽道結紮로 誘發된 白鼠의 損傷肝에 미치는 影響

李相祿,田炳薰,禹元洪,鄭遇悅 圓光大學校 韓醫學硏究所 1994 원광한의학 Vol.4 No.1

Prolonged bile duct ligation; a new experimental model for cirrhosis in the rat was carried out to elucidate the effect of Chijabakpitang(梔子柏皮湯) inhibiting the progress of thought to be enough to develop liver fibrosis or cirrhosis. The development of fibrisis or cirrhosis was progressive and associated with ascites. After the 7 week administration of Chijabakpitang on the bile duct ligation performed rat, the body weight, the hematological value, and the biochemical changes such as total bilirubin, direct bilirubin, asparate aminotranferase, alanine aminotransferase, akaline phosphatase, and the level of hydroxyproline in the liver tissue of the rat were examined. The results obtained were as follows. 1. The body weight in Chijabakpitang-administered experimental groups was inclined to increase, but it didn't significantly increase. 2. WBC counts significantly dicreased in Chijabakpitang-administered experimental groups, especially the decreasing value of serum WBC count in 1ml of Chijabakpitang-administered experimental group B was significant for all experimental duration. 3. Total bilirubin level decreased in 1ml of Chijabakpitang-administered experimental group B, and direct bilirubin significantly decrease in all Chijabakpitang administered experimental groups. 4. ALP level decreased in 1ml of Chijabakpitang-administered experimental group B, and ALT and AST significantly decrease in all Chijabakpitang-administered experimental groups. 5. The level of hydrwxyproline in the liver tissue of all experimental group significantly decreased.

연쇄가지반응 모델에 의한 화학반응 장치의 안전성

이상록,염치호,박찬규 동아대학교 공과대학부설 생산기술연구소 1997 生産技術硏究所硏究論文集 Vol.2 No.1

The method for determining the stability and multiplicity of steady states, and steady reaction region in phase plane for chain branching reaction model in perfectly mixed flow tank reactors is proposed. The results proposed are as follows : 1) stability and multiplicity of steady states exist 2 points (T_S1 : node, T_S2 : saddle) in T<T_1 range, and 2 points (T_S3 : focus, T_S4 : saddle) in T>T_2range on F(T)=0 curve. 2) steady reaction region containing the steady states can be constructed by the state varialbes of a reactor in phase plane. All trajectories of the representative points pass into the region at the boundary surface since the representative points in the region never drift out, it is safe to keep the reactor operation in the region.