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문은이(Eun Yi Moon),이진(Jin Lee),이원용(Won Yong Lee),최청하(Chung Ha Choi),이덕근(Dug Keun Lee),유제만(Jei Man Ryu),정용호(Yong Ho Chung),윤성준(Sung June Yoon),박경배(Kyung Bae Park) 한국응용약물학회 1997 Biomolecules & Therapeutics(구 응용약물학회지) Vol.5 No.3
DW-166HC (^(166)Holmium (^(166)Ho)-Chitosan complex) is a new radiopharmaceutic anticancer agent with a broad anti-tumorigenic spectrum, especially against human hepatic cancer. DW-166HC was evaluated for the appearance of micronucleus in polychromatic erythrocytes (PCEs) of mouse bone marrow cells after subcutaneous arid intravenous single administration. Bone marrow cells were prepared at 24 hr and 48 hr after DW-166HC-I (^(165)Ho-Chitosan complex : cold compound) administration and at 24 hr, 72 hr and 2 weeks after DW-166HC (^(166)Ho-Chitosan complex : hot compound) administration. The results showed there was no statistically significant increase of the numbers of PCEs with micronucleus in all DW-166HC-I administered groups compared with a negative control group but there was statistically significant increase of the numbers of PCEs with micronucleus at 24 hr arid 72 hr in all DW-166HC administered groups, which was recovered after 2 weeks from the drug administration. The results also showed the ratio of normochromatic erythrocytes (NCEs) to PCEs of all DW-166HC-I administered groups was not significantly different from that of a negative controi group but there was significant difference of this ratio at 24hr and 72 hr in all DW-166HC administered groups compared with that of negative group, which was also recovered after two weeks from the drug administration. These results suggested that DW-166HC-I may not cause any chromosomal damage but DW-166HC has in vivo mutagenic potential because of its radioactivity.
강의 수소취화에 대한 국부영역에서의 수소의 거동(Ⅰ) : 지연파괴의 수소집적에 미치는 응력 및 소성변형의 영향
이영호,이진우,배명일,고준빈,이규천 충남대학교 산업기술연구소 2001 산업기술연구논문집 Vol.16 No.1
Hydrogen embrittlement cause decrease of it's mechanical properties during hydrogen dissolved in steels. Many mechanisms of hydrogen concentration researches have done, but it is not clearly known yet. In this study the effect of plastic deformation and external stress on mechanism of hydrogen concentration by high temperature hydro-genation treatment were investigated. The main results are as follow : 1)For short time fracture process, a defect rate of chemical potential energy is an important factor on hydrogen concentration for delayed fracture of steel processed with high temperature hydrogen. 2)For long time fracture process, the important element is long range diffusion of hydrogen due to the rate of effective hydrogen density and plastic deformation. 3)hydrogen concentration as plastic deformation vary in proportion to slope of plastic deformation. 4)Hydrogen concentration due to the effect of external stress, but this effect is limited in short range. 5)External stress is an acceleration element for delayed fracture of steel.
김준섭,권오구,박진석,오종수,박정현,박제식,안세한,이용환,서정호,신태섭,최영배,김덕수,이관,박수경 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1
본 연구는 경주지역 1개 고등학교 3학년 여고생을 대상으로 초경 시작 전인 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레 수치와 초경 연령을 파악하여 여성의 초경이 빠를수록 체성장 속도의 변화가 있을 것이라는 가설을 기초로 두 요인간의 관련성을 파악하고자 시행되었다. 경주시 1개 여자고등학교 3학년생 총 317명에 대해 ㅊ경 나이, 초경시 심리 상태, 초경이 시작되었을 때의 상담 여부와 상담하였던 사람, 부모 신장과 초경전후의 식사 규칙성, 다이어트 경험, 수면시간, 스트레스, 음주/흡연 여부, 질병력 등에 대한 설문 조사를 시행하였고, 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레에 대한 정보는 건강기록부에서 확보하였다. 상기 대상자 중 건강기록부가 분실된 39명, 초경나이에 대해 응답하지 않았던 29명 및 결석 등으로 조사를 하지 못하였던 42명을 제외한 조사 대상자는 206명으로 선정하였다. 대상자들의 초경연령 평균값(Mean±SD)은 13.0±1.11이었고, 초등학교 4학년부터 고등학교 2학년까지의 초경 이후 신장 성장률은 감소하였으며, 초경연령이 빠른 군이 초등학교 때는 신장에 있어서 우위를 차지하나 고등학교에 오면서 신장은 비슷한 수준이 되었다. 초경후 1-2년 사이에 체중과 흉위의 증가율은 감소하였고, 초경연령이 빠른 군이 초등학교와 고등학교 사이에 체중과 흉위에서 모두 우위를 차지하였다. 본 연구의 결과는, 흔히 이차 성징의 시작 시점 혹은 사춘기의 시작 시점으로 보고있는 초경 연령이 청소년기의 성장과 밀접한 관련성이 있고, 특히 체중과 흉위의 성장 속도와 밀접한 관련성이 있음을 시사한다. To understand the onset of menarche in relation to changes in physical growth that take place during female adolescence, especially the changes in height and weight velocity. The 207 senior in one women high school of Kyongju were investigated in April 3 to 8, 2001. We collected the information, relation in the age at menarche, height & weight of parents, regularity of eating, and obesity diet, duration of sleeping, sickness & stress near age at menarche, by self-recording. The status of height, weight & chest circumference between the 4th grade of primary school and the junior of high school was collected by individual Health Record. The results were followed; The average age at menarche was 12.95±1.11 years old and the most frequent age of menarche is 13 years. After menarche, the velocity of height, weight and chest circumference were decreased. The most rapid group of menarche hold dominant position in height during elementary school. As time passed, they dont hold dominant position in height. The most rapid group of menarche get an advantage in the weight and the girth of chest after elementary school. The height of subjects is directly proportional to the height of their parents. These results suggest that the starting age at menestuation can be closely associated with physical growth and development.
( June Ho Bae ),( Jun Uk Lim ),( Kwang Ro Joo ),( Yu Mi Oh ),( Myung Joon Chae ),( Jung Won Jeon ),( Il Hyun Back ),( Hyun Phil Shin ),( Jae Myung Cha ),( Joung Il Lee ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Cholescintigraphy has traditionally been used as a tool to select patients with biliary pain for elective cholecystectomy. However, atypical biliary pain presents a clinical challenge and there is no literature evaluating the factors of the gallbladder wall related to abnormal ejection fraction of cholescintigraphy in such patients. Therefore, we aimed to evaluate characteristics of the gallbladder wall in patients with abnormal ejection fraction on cholescintigraphy and atypical biliary pain. Methods: Between April 2009 and April 2013, patients who underwent cholescintigraphy for atypical biliary pain and subsequent cholecystectomy at Kyung Hee University Hospital at Gangdong in Seoul, Korea, were initially recruited for this study. Parameters that were signifi cant on univariate analysis, including factors of gallbladder wall and cholescintigraphy, were subsequently tested by multivariate analysis to identify independent predictors for abnormal ejection fraction. Results: A total of 41 adult patients were divided into a low ejection fraction group (n=15) and a high ejection fraction group (n=26) based on the cutoff of 35%. In univariate analysis mean muscle thickness, muscle to total layer ratio, and muscle to fi brosis layer ratio were signifi cantly higher in the low ejection fraction group than in the high ejection fraction group. In multivariate analysis, the muscle to fi brosis layer ratio was found to be an independent risk factor for abnormal ejection fraction (odds ratio= 3.514, 95% confi dence interval= 1.058 - 11.673, p= 0.040). The fi brosis to total layer ratio was negatively correlated with ejection fraction in the low ejection fraction group (r= - 0.657, p= 0.008). Conclusions: Muscle to fi brosis layer ratio was signifi cantly associated with decreased ejection fraction. The fi brosis thickness ratio also seems to play an important role in patients with decreased ejection fraction.
배준호(June-ho Bae),손동경(Dong-kyung Sohn) 대한기계학회 2017 대한기계학회 춘추학술대회 Vol.2017 No.11
This paper aims to verify the applicability of open source code, OpenFOAM, to internal flows for the use of nuclear power plant flow simulation. For the verification, several representative flow cases are selected (Plain Couette flow with Pressure Gradient, Cavitation over a sharp-edged circular orifice, Converging-Diverging Nozzle). The simulation results are compared with experimental or theoretical result. Result from Plain Couette flow is similar with analytical solution. And for the Cavitation over a sharp-edged circular orifice, the coefficient of discharge, C<SUB>d</SUB>, is evaluated by experimental result. The Converging-Diverging Nozzle is compressible flow simulation from subsonic to supersonic flow fields. It shows that the flow fields are similar with analytical solution and the location of shock are well predicted. Based on this research, future study using OpenFoam is proposed.
후복막강 섬유화를 동반한 원인 미상의 경화성 장간막염 1예
배준호 ( June Ho Bae ),김성환 ( Seong Hwan Kim ),안상봉 ( Sang Bong Ahn ),손병관 ( Byoung Kwan Son ),조윤주 ( Yun Ju Jo ),박영숙 ( Young Sook Park ),정유민 ( Yu Min Jung ),장연수 ( Yeon Soo Chang ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.4
Sclerosing mesenteritis is a rare inflammatory disease of the bowel mesentery. It produces tumor-like masses of the mesentery composed of varying degrees of fibrosis, chronic inflammation, and fat necrosis. It has been described variously as fibrosing mesenteritis, retractile mesenteritis, mesenteric Weber Christian disease, and systemic nodular panniculitis. The etiology and pathogenesis of the disease are as yet unknown, but autoimmune disorder, previous abdominal surgery, trauma, and ischemia could play a role. The clinical features include abdominal pain, vomiting, diarrhea, and constipation. Occasionally, patients with this condition may present with bowel obstruction. Rarely, It can be associated with other idiopathic inflammatory disorders such as retroperitoneal fibrosis, sclerosing cholangitis, and orbital pseudotumors. We report a case of idiopathic sclerosing mesenteritis with retroperitoneal fibrosis in a 58-year-old man. (Korean J Gastroenterol 2011;58:221-225)
이온교환막 연료전지용 막 가습기의 운전 조건에 따른 성능 실험
배호준(Bae, Ho-June),김용모(Kim, Yong-Mo),이영덕(Lee, Young-Duk),유상석(Yu, Sang-Seok) 한국신재생에너지학회 2008 한국신재생에너지학회 학술대회논문집 Vol.2008 No.10
The efficiency and life time of the proton exchange membrane (PEM) fuel cell system is critically changed with its humidity which should be maintained properly during dynamic operation. Membrane humidifier is required to regulate proper humidity level for the design point of the PEMFC system. In this study, we presented the performance of the cylindrical membrane humidifier which is operated as water-to-gas. Dry air pressure, liquid water flow temperature, and air flow rate were chosen as the operating parameters. Humidity level is expressed with dew point.
DSSC(염료 감응형 태양전지) 모듈의 색 왜곡 최소화 및 색 재현성 향상을 위한 보색산정 연구
배호준(Ho June Bae),박종빈(Jong Bin Park),이현영(Hyunyoung Lee),송두삼(Doo Sam Song) 대한설비공학회 2022 대한설비공학회 학술발표대회논문집 Vol.2022 No.6
PV products applied to BIPVs about 99 % of all products in silicon solar cells. Although the initial BIPVs were simply attached to the roof or walls of the building, it caused problems that damaged the appearance of the building. To solve this problem, recently the application of the Dye-sensitized Solar Cell(DSSC) is increased. DSSC have a lower manufacturing cost and permeability than crystallized solar cells and do not rise the room temperature above 25 °C. DSSC can be colored and permeable depending on the dye used, showing excellent aesthetic characteristics when attached to windows or exterior walls. In these days, the studies for DSSC such as efficiency improvements and reliability tests have been conducted. In this study, the optical characteristics of the red DSSC module are analyzed and the complementary colors are calculated to improve the color reproducibility that affects the users work surface comfort. CIE color coordinates were converted into RGB codes, and complementary colors were calculated using the converted codes.