중력가속도의 변화에 따른 자동운반차량용 서스펜션의 진동모드에 관한 연구

주만식,김민주,이승수,최영철,추정근,김중완,전언찬 동아대학교 해양자원연구소 2000 硏究論文集 Vol.13 No.1

This study is to choose the most proper model for AGV Throughout simulation of behavior of suspension to reduce trial and error because there is no AGV treating heavy weight at harbor loading and unloading at home. Therefore, we estimate the vibration modes of the various suspensions applied to AGV, which is over 75 ton included the weight of two containers using the Matlab in the case of G and 5G, one of the simulation programs.

공동배양한 암세포와 혈관내피세포의 미세구조에 미치는 Nocodazole의 영향

김주영,송인환,이종용,성언기,이융창 대한해부학회 1999 Anatomy & Cell Biology Vol.32 No.4

국내외 ‘영아’ 관련 연구물의 최근 동향 분석 : 2000년~2013년 발간 논문을 대상으로

이승연,권수현,권연정,김언경,나영이,유주연,최정아 이화여자대학교 교육과학연구소 2015 교육과학연구 Vol.46 No.3

The purpose of this study was to examine research trends in infant research published from 2000 to 2013, in order to understand overall aspects in research topics, methods, and subjects in infant research and to suggest directions for future infant research. A total of 2916 journal articles and theses/dissertations, both domestic and foreign, were selected for the analysis. The findings of this study were as follows: First, for the 14 year period, 737 domestic articles, 634 domestic theses/ dissertations, 1242 foreign articles, and 303 foreign dissertations on infant research were published, and there was a steady increase in the number of articles and theses/dissertations over the years. Second, in terms of research topics, different patterns were found between the domestic ones and the foreign ones; the topic of “education and teachers” in the domestic ones and “development” in the foreign ones occurred most frequently. Third, in terms of research methods, the domestic ones employed “survey” the most, and the foreign ones employed “experiment” the most among quantitative research methods; when analyzing the relation between methods and topics, the foreign ones showed clear matches between topics and research methods, while the domestic ones preferred “survey” regardless of the topics. Fourth, in terms of subjects/participants, “infants” were the most researched in both the domestic ones and the foreign ones, followed by “parent” and “teachers.” Among the infants, the domestic ones focused on 25~36-month olds the most, while the foreign ones focused most on 0~12-month olds. In addition, in all types of infant research, there were more single subject studies than multiple subject ones.

朝鮮後期 佛殿莊嚴의 象徵性에 관한 硏究

李彦珠 동국대학교 불교대학원 1999 佛敎大學院 論叢 Vol.6 No.-

The Buddhism Flourishing to reach to 11 kinds of sects till Koryo Dynasty(高麗) was prone to declined to 7 at TaeJong(太宗) period, finally to Zen-doctrin 2 Sects (禪敎兩種) which disappeared, thanks to suppressing Buddhism at JungJong(定宗) period. So, it became Unified Buddhism, no sectarianized one with no sect-names, no sectary teachings. With this horrible reality, Buddhism was maintained with the forms of mountain-practicing Buddhism. It was Sungrang(僧郞) of monk-troops on Imjinwoeran(壬辰倭亂), 1592 that the suppress on Buddhism became lose somewhat, when monks were trying the rebuild or construct the damaged porporties of temples. While on the period of from late Koryo the early Chosun(麗末鮮初) technicians for reconstruction were scouted monks, by themselves did that on late Chosun Dynasty(朝鮮), covering from wood carving, stone carving, painting, making Bells, Danchung(丹靑) to petty things. In this situation, monks played toe major role in constructing. The Buddhist society focused 3 factors Zen(禪), Hwa-wom(華嚴), Chanting(念佛) on the basis of goal of Buddhism. With this result, constructers of late Koryo to early Chosun, before Imjinwoeran and those of after Imjinwoeran are quite differ in their outer-shape. So this thesis covers the research on about 50 Buddhist-alters telling the shift form Jusimpo(柱心包) matbae-roof of late Koryo to early Chosun to Dapo-Paljak-Roof(多包八作) style in late Chosun, changing in the number of Culmok(出目) below 2 to grow included. To this trend, Gondpo(공포) was carved to the shape of wave lotus(波蓮) and the shapes of Lotus, Dragon or chinese phoenix was added as the decoration. On the ceiling. Lotus Lantern style was diminishing and Lotus., Dragon, Bichonsang(飛天像), Unmun(雲紋), heavenly phoenix(極樂鳥) which represent Buddhapia were carved and added. These Kinds of changing were seen in Monsal(문살) and interior of BUddha Hall, too. In chapter Ⅲ, I tried to find the ground for these changes, In that era, the Buddhism was suffered from the restrict suppression whose reason the society. Just focused on mountain-Buddhism for with this stream, it was prevailing that they put importance on building Buddha-Halls or picture of Yongsanhoisang(靈山會相) with accordance to Hwa-om Sutra(華嚴經). In chapter Ⅳ, Firstly, They expressed endless virtue and beautifully, flower-elaborated Buddhapia. Secondly, Through the shape of heavenly phoenix, Bichonsang heavenly picture of ceiling we can see the heavenly world and Buddhapia of Yongsanhoisang, Thirdly, Through Dragon-head carved pillars of embankments they shows flowers are listening to Buddha's teaching and reached the other shore, Buddha-world already. These show the buddha-alter are the very Buddhapia, lotus-flower elaborated world. So far, we can find lots of theses of research related to constructers of National Treasures registered Buddha hall but not in those of the symbolism of them. That is the reason for existence of my thesis. even though there are things to be done and acquired more. I hope this thesis can be the first step of study more deeply about this field in coming future.

AGV 용 서스펜션의 진동 모드에 관한연구 : 중력 가속도가 5G인 경우 A Case of Gravity Acceleration is 5G

주만식,김민주,이승수,최영철,추정근,김중완,전언찬 한국공작기계학회 2000 한국공작기계학회 추계학술대회논문집 Vol.2000 No.-

This study is to choose the most proper model for AGV throughout simulation of behavior of suspension to reduce trial and error because there is no AGV treating heavy weight at harbor loading and unloading at home. Therefore, we estimate the vibration modes of the various suspension applied to AGV, which is over 75 ton included the weight of two containers on 5G using the Matlab, one of the simulation programs

枳實에 의한 아나필락시의 抑制效果

李彦政,朱泓炫,金炯均,宋峰根 圓光大學校 韓醫學硏究所 1996 원광한의학 Vol.6 No.1

The effect of water extract of Poncirus trifoliata fruit (ATFE) on compound 48/80 induced anaphylaxis was studied in the rat. The following results have obtained. 1. Optimal lethal dose of compound 48/80 was 8ug/gm B.W. 2. PTFE was found to exhibit an inhibitory activity on the anaphylaxis induced by compound 48/80. 3. Administration of PTFE 60 min before or 5 min after had a better result than 10 min after anaphylaxis induced by compound 48/80. 4. PTFE also inhibited significantly the serum histamine release in anaphylaxis induced by compound 48/80 in the rat. 5. Administration of PIFE before 30 min decreased PCA reaction induced by anti DNP-IgE and DNP-HSA. This result indicates that poncirus trifoliata suppresses the anaphylaxis induced by compound 48/80 with decreasing the serum histamine release.

암세포 단백합성기구에 미치는 Nocodazole의 영향

김선희,김주영,성언기,이융창 대한해부학회 1997 Anatomy & Cell Biology Vol.30 No.3

HeLa 및 Hep G2 세포의 미세구조에 미치는 Taxol의 영향

김광열,김주영,성언기,이융창 대한해부학회 1995 Anatomy & Cell Biology Vol.28 No.5

의무고용제도 재설계 방안

김종진,장창엽,유완식,김언아,이정주,류정진,강필수,최종철,남용현,김윤삼 한국장애인고용촉진공단 고용개발원 2008 연구개발 Vol.- No.2

현행 우리나라 의무고용제도는 장애인구의 급격한 증가, 장애인차별금지 및 권리구제 등에 관한 법률의 도입 등 외부환경변화에 신축적으로 대처하지 못하고, 경증장애인 중심으로 의무고용제도가 운영됨으로써 중증장애인의 고용배제가 우려되고 있다. 본 보고서는 이러한 문제점을 해결하기 위해 의무고용제도의 일자리 확대와 고용증가를 통해 중증장애인의 고용기회를 확대할 수 있는 정책방안을 제시하기 위한 것이다. 본 보고서는 (1)의무고용 사업체의 의무고용 산정인원에서 자립장애인 제외 (2)현행 2% 의무고용률을 3%로 상향 조정 (3)사업체가 고용하는 중증장애인에 대한 더블카운트(2배) 가산제도 도입 (4)의무고용률 미달 사업주에 대한 부담금 차등징수의 4가지 정책방안, 제도 합리화 차원에서 장려금 지급방식의 개선과 사업주의 장애인에 대한 인식개선 방안을 제시하였다. 정책방안에 대한 영향분석 결과 의무고용 적용대상자에서 비장애인과 고용상 차별되지 않는 자립장애인(6등급)을 의무고용 산정인원에서 제외하는 경우 의무고용 사업체의 고용인원은 23,296명이 감소해 고용률은 1.35%에서 0.88%로 감소하였고, 의무고용 사업체의 장애인 일자리 수는 미고용인원의 증가로 15,152개가 증가하였다. 그리고 기금은 부담금이 631억원 증가하고, 장려금이 352억원 감소해 983억원의 수지개선 효과가 발생하는 것으로 나타났다. 의무고용 사업주의 의무고용률 3% 인상 방안은 의무고용률 상향 조정에 따른 미고용인원의 증가로 장애인의 일자리 수는 43,101개가 증가하고, 기금은 부담금이 1,709억원 증가하는 반면, 장려금은 293억원이 감소해 2,002억원의 수지개선 효과가 발생하는 것으로 나타났다. 의무고용 사업주가 고용하는 중증장애인을 2인으로 더블카운트 하는 중증장애인 가산제도의 도입은 의무고용 사업체의 장애인근로자가 67,261명에서 79,685명(1,2등급만 포함시 75,685명)으로 증가하여 고용률은 1.35%에서 1.60%(1.2등급만 포함시 1.52%)로 증가하고, 의무고용률 미달 사업체의 미고용 인원이 감소하여 2,745개의 일자리가 감소하였다. 그리고 기금은 부담금이 118억원 감소하는 반면, 장려금은 418억원이 증가해 536억원의 수지악화가 발생하는 것으로 나타났다. 의무고용률 미달 사업체의 고용유인을 위해 고용률 1.0%미만, 1.0-1.5%, 1.6-2.0% 미만에 대해 각각 20%, 10%, 5%의 할증률을 순차적으로 가중하여 부과하는 부담금 차등징수 방안(3차년까지의 효과임)은 1.0% 미만 사업주는 86만원, 1.0-1.5% 사업주는 64만원, 1.6-2.0% 미만 사업주는 58만원의 부담기초액을 부과할 때 고용률은 1.35%에서 1.53%로 증가(1.6-2.0% 미만 사업주는 의무고용률 2%를 달성)하고, 미고용인원의 감소로 장애인의 일자리는 8,836개가 감소하는 것으로 나타났다. 그리고 기금은 부담금이 58억원 감소하여 수지는 악화되었다. 이상의 네 가지 방안은 모두 장애인의 고용증대를 가져온다는 측면에서는 유효하지만, 장애인의 일자리 확대를 통한 중증장애인의 고용을 증대한다는 정책목표를 달성하는 데에는 한계점을 안고 있기 때문에 어느 한 정책만을 선택하기보다는 정책효과를 극대화하기 위해 정책결합(policy mix)을 이용하는 것이 바람직함을 제시해주었다. 즉, 의무고용 적용대상자 조정방안/의무고용률 상향조정 방안과 중증장애인 가산제도/부담금 차등징수 방안을 조합 또는 모두 동시에 선택하는 경우 의무고용 사업체의 장애인 일자리 수의 확대와 중증장애인 고용을 동시에 달성하고, 기금의 수지균형도 달성 가능한 것으로 나타났다. The mandatory employment quota system of Korea does not reflect the changing external factors such as the growing population of people with disabilities(PWDs) and the enactment of the Anti-discrimination Law for People with Disabilities. The current employment quota system focuses on people with mild disabilities thus excluding people with severe disabilities from employment. The purpose of this report is to propose a plan in order to increase employment opportunity for the severely disabled through the reform of the employment quota system. This report analyzes the following : (1) exclude grade 6 disability from mandatory employment quota (2) raise the employment quota from 2% to 3% (3) implement the double counting for employers that employ the severely disabled (4) differentiate the amount of levy collected from corporations that are unable to meet the quota. The aforementioned plans are useful in that they increase employment for people with disabilities. However, there are limitation to reaching the policy objectives by increasing jobs for people with severe disabilities. Therefore, to maximize the effects we should consider policy mix of these four policies. In other words, by mixing the policies of adjusting the employment quota target/raising the quota ratio and implementing the double count/differentiating the amount of levy, we can achieve the goal of increasing jobs for the severely disabled and maintain equilibrium between incomings and outcomings.

<i>Gekkonidae</i>, Lizard tail extracts elicit apoptotic response against non-small cell lung cancer via inhibiting Akt signaling

Eon Lee, Joo,Lee, Dong Gwang,Park, Soon Yong,Jo, Ara,Kim, Hyoung Kyu,Han, Jin,Min, Jeong-Ki,Chung, Jin Woong Elsevier 2019 BIOMEDICINE AND PHARMACOTHERAPY Vol.116 No.-

<P><B>Abstract</B></P> <P>The genes of <I>Gekkonidae</I>, a lizard, are known to be very similar to human genes. According to previous research, lizard extracts inhibit angiogenesis and show anticancer activity against various cancers. In this regard, this study assessed whether lizard tail extracts (LTE) cause anticancer activity against lung cancer in mouse and human lung cancer cell lines. The results showed that LTE exhibited anticancer activity against lung cancer in vitro and in vivo. In vitro, cell viability and proliferation decreased in two lung cancer cell lines, while annexin V and single-stranded DNA both increased, showing apoptotic activity caused by LTE. We also found that LTE induced apoptosis in a caspase-3/7 cascade-dependent manner and inhibited the phosphorylation of Akt by participating in the PI3k/Akt pathway. In vivo, LTE decreased tumor volume in LLC bearing mice. Our results demonstrate the potential of LTE as a natural-derived anticancer drug to overcome the chemotherapy side effects during cancer treatment and contribute to the discovery of candidate substances.</P>