외과적 노출술을 이용한 매복된 하악 제 1 대구치의 자발적 맹출 유도

김은정,김난진,조호진,김현정,김영진,남순현 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.4

하악 제 1대구치 매복의 발생 빈도는 전체 인구의 0.01%로 드물게 나타난다. 매복의 원인으로는 맹출 공간의 부족, 과잉치, 치성 종양이나 낭과 같은 맹출로상의 장애물, 유전적 요인, 내분비 질환, 외상 등이 있다. 하악 제 1대구치의 매복으로 인해 하안면 고경의 감소, 낭의 형성, 치관 주위염, 인접치의 치근 흡수, 부정 교합 등의 부작용이 생길 수 있으며, 치료 방법으로는 외과적 노출술, 교정적 견인, 외과적 재위치술, 발거 등이 있다. 다음의 두 증례는 하악 제 1대구치의 미맹출을 주소로 내원한 환아에게 외과적 노출술을 시행하여 원심 경사 매복된 하악 제 1대구치의 자발적 맹출을 유도한 증례들이다. Impaction of mandibular first molar is relatively rare and its overall frequency has been reported to be 0.01%. The etiology of impaction are lack of eruption space, physical obstacles such as supernumerary teeth, odontomas or odontogenic tumors, hereditary factors, functional disturbances of endocrine glands and traumas. Impaction of mandibular first molar can result in a short lower facial height, formation of a follicular cyst, pericoronal inflammation, resorption of the roots of neighboring teeth and malocclusion. The treatment options available for impacted teeth include surgical exposure, orthodontic forced eruption, surgical repositioning and surgical removal of unerupted molar. This report presents two cases of distally tilted and impacted mandibular first molars which were treated by surgical exposure. In these cases, we could observe spontaneous eruption of the impacted mandibular first molars after surgical exposure.

김치 유산균인 Lactobacillus sp. JJ-2001이 생산하는 Bacteriocin에 관한 연구

조영배,조우제,조영임,이은주,김성구,전홍기 부산대학교 유전공학연구소 1997 분자생물학 연구보 Vol.13 No.-

The microorganisms producing bacteriocin from kimch were screened, and among them,a strain showing the highest bacteriocin activity and stability was isolated. Based on the taxonomic characteristics of its morphological, cultural and physiological properties, the isolatef strain was characterized as Lactobacilius sp..To identify optimal conditions for the growth and the production of bacteriocin from the isolated strain,nutrient source, initial pH, and culture temperature were evaluated. Physiochemical properties of bacteriocin was also investigated. The potimal condition for the production of bacteriocin and the cell growth was obtained at 2% glucose, 1% beef extract as organic nitrogen source,1%(NH_4)_2SO_4 as inorganic nitrogen source,and 0.1% Tween 80. The isolated strain showed the maximum growth at 25℃. The inhibitory range of its antimicrobial substance aginst gram positive bacteria was marrow and its inhibitory activity was maintained between pH3.0 and pH8.0. The antimicrobial activity of bacteriocin from the isolated strain was stable at 50℃.

스포츠 관광 활성화 개선방안에 관한 연구

조충현,김홍식,박은석,강성찬,이동헌 圓光大學校 附設 體力科學硏究所 2003 體力科學硏究 Vol.26 No.1

This study was conducted to investigate the effects of the marketing strategy based on the traditional wrestling, which affects the tour industry. The study used the simple random sampling method in the group of the Kwang-Ju district citizens. The group representatives were directly interviewed, and 277 interviewees replied with concern. The rest of the interviewees were not interested in the survey. The general characteristics of the interviewees -- gender, age, education, job, monthly salary. -- were used to analyze the items related to Sports Tourism in general. Sport Tourism in general Male interviewees had higher recognition over females in the interview. The rate of experience was low for both genders. According to their education, the satisfaction of sport tourism showed low rate. However, there were many answers where the interviewees, not depending on the age or gender, indicated that they will participate in the future. The policy recommended based upon the results of the study is as follows. There is a need for setting up a new strategy in order to increase participation of sports. Also, it is urgent to set up a sports theme center to raise professional sportsmen and to supply them to where they are needed.

결핵군 55 kDa 항원의 면역학적 분석

김화중,김홍성,임재현,조은경,송창화,박정규 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1

Identification and characterization of mycobacterial antigens are critical for evaluation of their role in diagnosis, vaccination, and pathogenesis of mycobacterial diseases. An attempt has been made to immunologic characterize the 55 kDa protein antigen of Mycobacterium tuberculosis H37Rv which attracted our interest because it is present in high concentration in 50-80% ammonium sulfate fraction of the culture filtrate. Two monoclonal antibodies (MAbs) directed to 55 kDa antigen were produced. MAbs MT55-1 and MT55-2 reacted with a single 55 kDa protein band. On examination of degree for cross-reactivity with other mycobacterial species by enzymelinked immunosorbent assay (ELISA) and immunoblotting, these antibodies reacted strongly with M. tuberculosis and M. bovis BCG, and reacted weakly with M. marinum and M. smegmatis. To investigated the subcellular distribution of MAbs defined epitopes in the 55 kDa antigen within the mycobacterium, we isolated three major subcellular factions of M. tuberculosis, namely, cell wall, cytoplasmic membrane, and cytosol, by a simple fractionation procedure. MAb MT55-1 reactive cpitope was found in the cytosol when tested by immunoblotting. A sandwich ELISA was initially developed for detecting 55 kDa antigen using MT55-1 MAb in mycobacterial culture filtrate before detecting it in clincal specimens. The minimal detectable concentration was 1.0 ㎍/m1 for M. tuberculosis culture filtrate and 100 ㎍/ml for sonic extracts of M. bovis BCG and M. marinum, respectively. But the 55 kDa antigen was not detected in sonic extracts of other mycobacterial species examined. Although further evaluations are required, this study suggests that the 55 kDa antigen may be of interest as potential diagnostic reagent.

감꼭지나방 생태적 특성 및 방제약제 선발

김정화,김길하,조수원,박은철,김순섭,황태구,최상기 충북대학교 첨단원예기술개발연구센터 1999 연구보고서 Vol.4 No.-

경남지역과 충북지역 감나무의 재배, 해충 방제실태를 농가 방문하여 설문조사 한 결과 감 재배경력은 경남지역이 평균 10년이며, 충북지역은 평균 5년 정도이다. 감 재배 주수는 대다수 농가가 20주 이상이고, 재배관리에 대하여 자문을 받는 곳은 농업센터나 농약사 및 연구소 등이었다. 김 품종은 경남지역에서는 부유와 서촌조생, 충북지역에서는 등시와 월하 등을 재배하고 있었다. 시비종류는 이른봄 에 퇴비나 복합비료를 주었고, 감나무 생장 중 열매나 저장 중 열매에 발생하는 해충이 발견되었다. 해충방제를 위해 살충제를 살포하고 있는데 주로 감꼭지나방, 진딧물, 잎말이나방 및 깍지벌레 등으로 파마치온, 파단, 코니도, 신파마치온, 수프라사이드 등을 살포하였다. 감꼭지나방(Stathmopoda masinissa)의 발육생태를 조사하기 위하여, 감꼭지나방을 야외에서 채집하여 온도±1℃, 광주기 16L:8D, 상대습도 50~60%에서 실내 사육하였다. 각 층태별 기간은 알 7.4일, 유충기간 34.7일, 용 15.5일이었다. 각 령기간은 1령 3.5일, 2령 4.2일, 3령 5.2일, 4령 6.5일, 5령 15.4일이었으며, 특히 유층의 두폭을 측정하여 평균한 결과는 1령 0.20mm, 2령 0.40mm, 3령 0.65mm, 4령 0.87mm, 5령 1.07mm일 이었다. 성충의 수명은 수컷이 6.2일, 암컷이 10.1일 이었다. 용화율은 68.0% 우화율은 59.9%이었다. A survey in Kyungnam and chungbuk areas revealed that the average number of years for persimmon tree farming is 10 and 5 years, respectively. The number of trees per orchard is at least over 20, and the farmers have been usually advised through an agricultural center, an agrochemical store, or agrochemical research center. The varieties of the persimmons they grow are Buyu and Seocheon in Kyungnam, and Doogsi and Wolha in Chungbuk. The kind of fertilizers they sprayed in early spring is either compost or composite fertilizer. persimmon pests are often found in persimmon fruits while on a tree or in storage. Phamathion, Padan, Konido, Sinpamathion, and/or supuraside is usually used to control persimmon fruit moths, aphides, leafrollers, and scale insects. To understand the developmental ecology of the persimmon fruit moth, Stathmopoda masinissa Meyrick, we collected and reared them under the laboratory condition which is at 25±1℃ of temperature, 16L:8D of photoperiod, and 85% of relative humidity. As a result, the developmental period of egg, larva, and pupa were 7.40, 34.7, and 15.5 days, respectively. The average period of each larval instar was 3.50, 4.17, 5.17, 6.46, and 15.42 days, respectively, and the average head capsule width was 0.20, 0.40, 0.65, 0.87, and 1.07mm, respectively. The average adult longevity was 6.2 days for males and 10.1 days for females. The pupation rate and the emergence rate were 68.0% and 59.9%, respectively.

pH, 화학적 조성 및 첨가제가 두유(豆乳)의 현탁안정성에 미치는 영향

김은수,정성수,조재선 경희대학교 부설 식량자원개발연구소 1990 硏究論文集 Vol.11 No.-

두유를 저장하고 유통하는 중에 크림층 분리와 침전물의 발생 등 현탁안정성에 미치는 pH, 단백질과 유지함량, 유화제, 안정제, 당, 식염 및 칼슘염의 영향을 조사하였다. 두유현탁액은 pH가 증가할 수록 침전의 발생이 적어져 pH 10에서는 저장하는 동안에 침전이 전혀 생성되지 않았다. 각종 안정제 중 0.03%의 카라기난을 첨가시 안정성이 가장 좋았으며 팜유를 1.5% 첨가시 glycerine monostearate 와 sorbitan monostearate 등의 HLB 값은 5~6에서 안정효과가 컸다. 두유 중 지방 함량에 따라 점도변화는 크지않았지만 크림층 분리가 현저하였고 대두유보다는 팜유를 첨가시 안정성이 더 떨어졌다. 설탕 첨가량은 3%까지 안정성에 큰 영향을 주지않았고 식염은 0.5%까지는 첨가량이 증가할 수록 안정성이 감소되었다. 각종 칼슘염 중에서는 모두 안정성을 저해하였지만 그 중에서 시트르산칼슘을 첨가시 안정성의 저해정도가 가장 적었다. The effects of pH, protein and fat content, addition of emulsifiers, stabilizer, sugar, salt and calcium salt on the stability of soymilk suspension were investigated by analyzing the cream separated and precipitates of soymilk which is prepared by various conditions. In the alkaline region of pH, soymilk showed a good stability of the suspension and particularly, above pH 10, precipitates were not formed. When 1.5% of palm oil with 0.4% of glycerine monostearate was added to soymilk in the hydrophile-lipophile balance (HLB) value of 4 to 7, resulted maximal emulsion stability occured below HLB 6. The stability was decreased with increasing the fat concentration and soy oil showed better emulsion stability than that of palm oil. Among the commercial stabilizers, 0.03% of carrageenan was most effective. The stability was not decreased by addition of sugar up to 3% while it was decreased by addition of sodium salt and calcium salt at low level.

두유(豆乳)의 현탁안정성에 관한 연구

김은수,조재선 경희대학교 부설 식량자원개발연구소 1990 硏究論文集 Vol.11 No.-

두유제품을 저장하는 동안 단백질 등의 침전과 지방질의 크림층이 분리되는 현상에 미치는 두유제조 조건의 영향을 검토하기 위해서 분쇄, 균질처리 및 열처리조건이 두유의 현탁안정성에 미치는 영향을 조사하였다. 먼저 20℃의 물로 마쇄한 것을 blanching시 온도에 반비례하여 질소 용해도지수가 현저히 감소하였으나 80℃의 물로 마쇄하는 경우 그 감소폭이 20℃의 경우보다 적었다. 침지 대두를 분쇄하여 단백질 입자가 53μ에서 8μ으로 작아질 수록 침전량이 감소하여 두유의 현탁안정성이 증가하였고 균질처리를 1회한 것보다는 2회 반복초리한 것이 안정성이 증가하였으며 1회 처리시는 입자의 크기에 따라 차이가 심하였지만 2회 처리시는 그 차이가 감소되었다. 균질처리시 1단계 처리압력이 200kg/㎠까지는 안정성이 증가하였고 팜유를 첨가하여 균질처리를 할 때의 온도가 80℃까지 온도를 높일 수록 안정성이 증가하였다. 두유제품을 살균할 때 열처리온도가 120~125℃에서 30분 이상 열처리시에는 안정성이 급격히 감소되었다. The effects of blanching, homogenization and heat sterilization on the stability of soymilk suspension were investigated by determination of nitrogen solubility index(NSI) of suspension and measuring the volume of precipitates and cream separated. The results obtained were that the NSI was decreased as the blanching temperature increased from 50 ℃ to 80 ℃. The soybean particles having 8p by grinding showed more stable soymilk than that of 53 p. The stability was increased as the homogenizing pressure increased to 200 ㎏/cm^(2) and repeated homogenizing process gave more stability than single one. The sterilization resulted a significant decrease in stability as it was heated at 120℃-125℃ for more than 30 minutes.

스코어 기반 스팸 메일 필터링 기술을 추가한 메일서버 스캐너 개선 연구

김영현,김명주,최은정,박은옥 서울여자대학교 컴퓨터과학연구소 2003 정보기술논문지 Vol.1 No.-

본 눈문에서는 정보화 사회에 있어서 E-mail 사용의 확산과 그에 따라 발생하는 컴퓨터 바이러스, 웜, 스팸메일 등의 출현에 따른 문제의 예방책으로써 메일서버스캐너를 제시한다. 이러한 필요성에 기반하여 기존의 개발된 메일스캐너의 개념을 이해하고 기능을 분석한다. 기능 분석을 통해 각각의 메일스캐너의 단점을 개선하고 장점을 강화하는 등의 새롭게 보강된 메일서버스캐너 기술을 제안한다. Indicated in this paper are the problems followed by the proliferation of use of E-mails in this information-oriented society and the advent of computer viruses, worms and spam mails. Mail server scanners for servers are also discussed as a countermeasure. Concepts of conventional mail scanners are described and its functionality is analyzed. New technologies for mail server scanners, reinforced by functional analysis of conventional mail scanners, are suggested. Moreover, IMScanner described in this paper offers detection of unknown malicious codes based on form analysis, in addition to strong 3-level filtering.

製紙工程에서 分離한 슬라임 形成細菌의 最適 生長條件 探索

김은희,조병묵,오정수 동국대학교 생명자원과학대학 연습림 1997 연습림논문집 Vol.- No.5

The eight bacteria isolated from paper­making process were tested under the condition of 30℃, 35℃, 40℃ with pH 5, 7, 9. The growth of Pseudomonas paucimobilis B was the most excellent at 30℃ with pH 7. Staphylococcus sapropyticus was very good at 35℃ with pH 7 and pH 9. Pseuomonas cepacia generally grew well at every pH condition except for 40℃, pH 9. Acinetobactor calcoaceticus was excellent at 35℃ with pH 7 and at 30℃ with pH 9. Actinobacillus capsulatus showed the good growth in every tested condition except for pH 5 of 35℃, 40℃. The unidentified sprain was very good at 35℃ with pH 7 and pH 9. Staphylococcus auricularis had a unique growth pattern at pH 9 at every tested temperature condition. Acidovorax sp. was good at pH 7 and pH 9 of 30℃, 35℃, 40℃. This isolated bacteria generally showed good growth at pH 7 of 35℃, 40℃.

Multiple myeloma 환자에서 Bortezomib치료 후 발생한 마비성 장폐색증 1례

김준영,이원식,손창학,박성길,진한영,박석주,조영완,정은욱,강명주,박정하,주영돈 인제대학교 2006 仁濟醫學 Vol.27 No.-

Bortezomib is the first clinically available proteasome inhibitor that is clinically effective in the treatment of multiple myeloma. A proteasome inhibitor acts through multiple mechanisms to arrest tumor growth, tumor spread, and angiogenesis. The main adverse effects of bortezomib are gastrointestinal symptoms, cytopenia, fatigue, and peripheral neuropathy. To date, severe paralytic ileus has not been reported as a toxic effect of bortezomib treatment in multiple myeloma. Bortezomib is a novel agent that has only been used clinically for 30 months, so a need exists to further evaluate its toxicity. We report a case of grade Ⅲ (NCI CTCAE v3.0) or grade Ⅳ(SWOG toxicity criteria) paralytic ileus in a 65-year-old man with relapsed multiple myeloma who underwent one cycle of single-agent bortezomib treatment scheduled in a 21-day cycle (1.3 mg/㎥ as a single i.v. bolus on days 1, 4, 8, and 11).