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심상성 조창에 대한 Panoxy 2.5 ( 2.5 % Benzoyl Peroxide Gel ) 의 치료효과
김홍식,조광현,이유신,김원석,남태중 대한피부과학회 1979 大韓皮膚科學會誌 Vol.17 No.3
Bezoyl peroxide, a powerful oxidizing agent, has been uaed topically in the treatment of acne vulgaris as a cream or lotion and has been shown to he effective for this codition. In 1972 Fulton emphaaized the importance of the vehicles used to obtain. maximum potential of benzoyl peroxide and for this, the gel formulation has been examined in many clinical trials. The present study was undertaken to evaluate the therapeutic effect of Fanoxyl 2.5^ⓡ, a 2.5% . benzayl peraxide gel, in patients with acne vulgaris. A total of 31 patients entered this study at the Departrnent of Dermatology, Jeoul National University Hospital rluring 3 rnanths period, from Decemher, 1978 through February, 1979, All patienta were instructed to apply Fanoxyl 2.5^ⓡ on their affected areas once or twice a day and the nurnber of lesions on two or three t fixed areas were counted before and onee weekly after initation of the treatment. The reaults observed in the 3I patients were as follaws; 1. The percentage decrease in total nurnber of lesions in 4 weeks after treatment was 56.9%. 2. The authors could follow up for 6 weeks in 6 cases. In 6 case, the mean percentage in total number of lesions in 6 weeks after treatment was 81.7%. 3. Clesed and open eomedones were gradually eliminated; and their numbers were decreased in 4 weeks after treatment by 46.5% and 56.8% respeetiveIy. The papules were rapidly eliminated and their numbers were decreased in 4 weeka, after treatment by 79.8%. 4. Although most patients felt a mild burning sensation and tightness at the begining of the treatment, only a minority of the patients complained of discomfort due to pain(l case), erytherna(l case), tightness(2 cases),burning sensation (1 case), scaling(1 case). But all were tolerable without taking any specific measures or discontinuance of application. In one case, contact dermatitis developed after 4 weeks treatment. The authors concluded through this experiment that Panoxyl 2.5^ⓡ (2.5% benzoyl peroxide gel) is a very effective local therapeutic agent in the treatment of acne vulgaris patients.
김홍식,강범규,서정현,김현태,하태정,오재현,신상욱,백인열 한국작물학회 2021 Journal of crop science and biotechnology Vol.24 No.2
There is great interest in the enhancement of isoflavones as one of the functional ingredients in soybean. This study aimed to investigate the effects of changes in the ecological environment over different planting times on isoflavone content. A total of 28 Korean soybean cultivars were grown at different planting times in late May, mid-June, and early July and their isoflavone content was measured over 2 years (2017 and 2018). Analyses of variance revealed significant effects of genotypes, planting times, years, and their interactions on isoflavone content. The average content of total isoflavone, as well as its component groups of malonylglucoside and aglycon, increased significantly as the seed planting time was delayed from late May to early July. The accumulation of each isoflavone component varied with changes in the planting time. The isoflavone content of the soybean cultivars for soy-sprout and soy-paste and tofu were higher for plantings in early July than for those in late May and/or mid-June, except for the black soybean cultivars. Despite significant correlations of the isoflavone content of the 28 cultivars among the three planting times, the responses of individual cultivars varied in isoflavone content by planting time. When planting was delayed, the time to flowering and maturity was also delayed and the number of days of growth from planting or flowering to maturity decreased; however, this was not related to isoflavone content. When planting was delayed, the temperature during the ripening period from flowering to maturity was lower, which was inversely related to the isoflavone content.
김홍식 대한피부과학회 1976 대한피부과학회지 Vol.14 No.1
It is well known that there are many kinds of strains of fungi in the atmosphcre and important problems of the relationship between these microorganisms and human bcing. The survcy vas performed to find the source of fungal infection by the determination of pathogenic fungi at the sites of much frequented travelIed, very confused perdestrian traffic, contaminated indoors of hospital huilding. For the purose of clctermining the aerial fungi collected at the selected areas in clinic of Seoul National University Haspital (out-patient roorn and corridor, kitchen room, corridor of operating room, pharmacy floor, supply room and in-patient rooms) by sampling method of gravity seilimentation by 5 minutes exposure of Sabourands glucose agar plate (5cm. diarmeter dish) and identified the fungi macroscopically and microscopicalIy. The results are as follows; 1. From 8 indoor ares of hospital, 441 colonies were sampled and average number of funga1 co!onies in each of the agar plate was computed to 3,675 colonies. 2. Total generas abtained by cultivation were 9 generas, and the common fungi in air were hormodcndrurn(18. 59%), penicillium(17.68%) and aspergilIus (16.55%) in crder frequency. 3. No pathogenic fungi were isolated, and it is assumed that there is no radical problem of infection source in hospita.I indoors practicalIy.
피부표재성 (皮膚表在性) 백선 의 통계및 균학적 (菌學的) 관찰
김홍식 대한피부과학회 1971 大韓皮膚科學會誌 Vol.9 No.1
The study was made in order to investigate the present status of superficial dermatomycoses and some changes on the frequency of the diseases, sex distribution and varieties of the causative organisms by the statistic and mycological observation. The survey was made by out-patients of Dermatology clinic of Seoul National University during 3 years, from 1967 to 1970. The results are as follows: 1. Tinea (T) capitis shows a great decrease (1/4) and T. cruris shows a increase in number as compared with those of during 1957-1960. 2. In T. capitis the number of male cases is equal to that of female cases. It is remarkable difference that the ratio of sex distinetion showed 25 males against to one female during 1967 to 1970. 3. The strains were isolated by ordinary sabouraud's glucose agar media and obtained 4 species, 125 strains. a. Tr. rubrum was most predominant organism of T. pedis & manum, T. cruris, T. corporis and Onychomycosis in Seoul districs. b. Tr. ferrugineum was most common organism of T. capitis (80%).