항암제 AG60이 흰생쥐 위점막 상피세포의 DNA합성에 미치는 영향 : 자기방사법적연구

박경호,안의태,고정식,하상선,한영복,정영신,홍은경,유보림,김상건,이경영,강종구 대한해부학회 1999 Anatomy & Cell Biology Vol.32 No.1

저체중 또는 과체중 청소년에서 캠프 프로그램을 이용한 영양 교육효과에 관한 연구

성미경,승정자,류화춘,박재년,박동연,최미경,조경옥,최선혜,이윤신,김유경,이은주 대한지역사회영양학회 2003 대한지역사회영양학회지 Vol.8 No.4

This study was performed to evaluate the effectiveness of a nutrition education program developed for nutritionally imbalanced adolescents. A summer nutrition camp was held for 23 overweight and 16 underweight subjects. Its effectiveness with regard to was evaluated at the end of the camp and 6 months later. Nutrition knowledge, nutritional attitude, food behavior, nutrient intake, exercise habit and ideal body figures desired by the subjects. The results showed significantly higher nutrition knowledge scores at the end of the camp as compared to those obtained prior to the camp program, and these scores were maintained for at least six months. Nutrition attitude scores also improved after the education program, and these improved scores also lasted for 6 months. However, the food behavior scores measured 6 months after the education program were not significantly different from those obtained prior to the camp. Also, the exercise habit, the ideal body figures and the body figures desired by the subjects remained unchanged. When nutrient intakes of subjects were assessed before the program and 6 months later, the mean daily vitamin C intake was significantly increased after the education program. Also, the intake of iron from plant food sources increased in the overweight subjects, while less iron from animal source were consumed by the underweight subjects. Both groups tended to consume more vegetables and fruits 6 months after the education program which may have contribute to the higher vitamin C and plant-based iron intakes. These results indicate that a 4-day nutrition education camp program sustained changes in nutrition knowledge and nutrition attitude for 6 months. The increased intake of vegetables and fruits was also achieved through this education program. However, changes in dietary behavior in adolescents may require repeated education.

팽이버섯의 저장성에 미치는 광석분말을 함유한 한지의 포장효과

이예경,신경옥,정유경,박범호,김순동 동아시아식생활학회 2004 동아시아식생활학회지 Vol.14 No.5

The effect of polyethylene film(PE) packaging of golden mushroom wrapped with Korean paper containing 20% mica powder on the changes in weight, color, texture, PPO activity, number of total microbe(TM) and sensory quality during storage at 10℃ were investigated. The experiments were divided to 3 groups(control; only PE packaging, KP; PE packaging wrapped with Korean paper up and down of the sample, KPM; PE packaging with Korean paper containing 20% mica powder up and down of the sample). The weight of the mushroom in the KPM was the lowest until 9 days-storage, but the weight was the highest at 15 days-storage, showing 12.5% higher against the initial weight. L^(*) values of the mushrooms in the control and KP treatment were decreased, but the value in the KPM treatment was maintained as the same of the initial value during storage. The increasing rate of a^(*) and b^(*) values in the all plots during storage was the lowest in KPM and in order of KPM<KP<control. The activity of PPO and number of TM in the KPM treatment were maintained the lowest, but hardness and gumminess were maintained the highest during storage. Appearance of the mushroom stored for 15 days was the best, the degree of browning and softening were the lowest in the KPM. Off-flavor was lower in all plots, but the scores were the lowest in KPM. But further study on the fruit body was grown in the KPM at after-period of storage was required.

Kartagener 증후군을 동반한 일차성 섬모 이상운동증 1례

변은경,조유경,송현주,이현경,이진화,성순희,김유경,장중현 梨花女子大學校 醫科大學 醫科學硏究所 2002 EMJ (Ewha medical journal) Vol.25 No.1

Primary ciliary dyskinesia is a genetic disorder of abnormal ciliary structure and function that leads to defective mucociliary clearance, resulting in sinopulmonary infection and infertility. Kartagener's syndrome is a subclass of primary ciliary dyskinesia and which is clinically distinguishable by the presence of situs inversus. Electron microscopy of cilia reveals ultrastructural defects in the ciliary axoneme. In the respiratory tract, this inability presumably causes impaired clearance of mucus and inhaled particles and results in the chronic infections of sinuses and bronchial trees that are characterized of the disease. Early diagnosis of the disease may be important for prevention of bronchiectasis and pulmonary insufficiency. We report one case of primary ciliary dyskinesia associated with Kartagener's syndrome in a 14 year-old young man who was presented as bronchiectasis, chronic and situs inversus, with review of literature.

비만 성인에서 복부 내장지방과 단순 비만 지표와의 연관성 연구

유진숙 ( Jin Sook Yoo ),송윤경 ( Yun Kyung Song ),임형호 ( Hyung Ho Lim ) 한방재활의학과학회 2010 한방재활의학과학회지 Vol.20 No.2

Objectives: This study examined search on how the obesity indices, that are largely used in clinics such as waist circumference(WC), body mass index(BMI) and waist-hip ratio(WHR), are related to the visceral fat that was measured from abdominal computed tomography(CT) and the ratio of visceral fat/subcutaneous fat. Then, two groups were compared in order to find out which characteristics of ordinary adults relationship with the abdominal obesity. Two groups are divided as follows; ones who are obese based on the measurement of WC and the others who are obese based on the level of BMI. Methods :A group of 63 test subjects that were gathered in the oriental medical hospital of Kyung-Won university is divided into two groups; ones (n=51, general obesity; group A) who have BMI≥25 and WC≥85, and the others (n=12, abdominal obesity; group B) who have BMI<25 and WC≥85. Then, each group’s obesity indices, abdominal CT, lipid level, glucose, adiponectin, leptin and C-reactive protein(CRP) are compared. In addition, subjects are again divided into two to examine the characteristics; ones (n=14, visceral obesity; group C) with visceral obesity based on the ratio between visceral fat and subcutaneous fat measured through abdominal CT, and the others (n=38, non-visceral obesity; group D) who are obese but not viscerally obese. Results & Conclusions :As a measurement that applies abdominal visceral fat and subcutaneous fat, BMI and WC can be considered as an appropriate obesity index while WHR cannot appropriately apply the abdominal fat amount. Moreover, the study indicates that abdominal obesity group based on the ratio of visceral fat/subcutaneous fat has more significant difference than the abdominal obesity group based on the WC in case of blood lipid index.

계류 유산 후 한방치료 위해 내원한 환자의 Heart Rate Variability(HRV) 특성 연구

유은실 ( Eun Sil Yoo ),김민영 ( Min Young Kim ),황덕상 ( Deok Sang Hwang ),이진무 ( Jin Moo Lee ),장준복 ( Jun Bok Jang ),이경섭 ( Kyung Sub Lee ),이창훈 ( Chang Hoon Lee ) 대한한방부인과학회 2015 大韓韓方婦人科學會誌 Vol.28 No.3

Objectives: This study aims to analyze Heart Rate Variability (HRV) in women after missed abortion compared with healthy women Methods: We studied 35 women who visited Kang-Nam Kyung-Hee Korean Hospital after missed abortion from 01 January 2012 to 28 February 2015 (missed abortion group) and 35 normal women visiting medical examination center from 1 January 2014 to 31 December 2014 (Normal Group). We measured HRV of each women and investigated the difference of HRV between two groups. Results: The standard deviation of NN intervals (SDNN) in Missed abortion group is lower than normal group. The square root of the mean square difference of successive NNs (RMSSD) in Missed abortion group is lower than normal group. However there was no significant difference. Total Power (TP) and Low frequency power (LF) is significantly lower in Missed abortion group compared with normal group. High frequency power (HF), Very low frequency power (VLF) and LF/HF ratio in missed abortion group is lower than normal group. but There was no significant difference. Conclusions: Missed abortion group is lower in function of overall autonomic nervous system, especially sympathetic nerve.

『文化柳氏 嘉靖譜』와 『安東權氏 成化譜』나타난 貞顯王后의 人的 關係網

柳炅來 한중인문학회 2009 한중인문학연구 Vol.26 No.-

본 논문에서는 『文化柳氏 嘉靖譜』와 『安東權氏 成化譜』에 수록된 朝鮮 初期 妃嬪들 가운데 한 명인 貞顯王后 尹氏의 선대를 遡及·考察하면서 重疊된 通婚圈에 중점을 두어 조선 초기 지배층의 성향을 살펴보았다. 정현왕후의 坡平 尹氏 家門은 고려 전기 이래 門閥貴族家門으로서 忠宣王이 宣布한, 왕실과 혼인할 수 있는『宰相之宗』가문의 반열에 올랐다. 그리고 조선 초기에 들어와서도 國婚과 기타 功臣·鉅族·家門들과의 통혼을 통해 가세를 신장시켰다. 본고에서는, 親孫 및 外孫 계열 후손에 이르기까지 대를 한정하지 않고 수록한 족보인 『가정보』와 『성화부』를 통해 당대 지배층 가문들간의 중첩된 혼인 관계를 살펴보았다. 그리고 이를 통해 정현왕후가 자신의 시어머니(姑)인 昭惠王后까지 포함하여, 鄭昌孫, 韓明澮 등을 비롯한 고려 후기 및 당대 여러 유명 인물들과 혈연 관계로 맺어진 人的 關係網을 발견할 수 있다. In this paper, we examined ancestors and lineage of the Jung-Hyoun Wang Hwoo(貞顯王后: 1462~1530; empress named Jung-Hyoun)-the empress of the Chosun dynasty 9th King Sung-Jong(成宗: 1457~1494), listed on the two famous genealogy, 『Munhwa Liu Ssi Jiajingbo(文化柳氏嘉靖譜: Munhua Liu Genealogy of Jiajing Era』 and 『Andong Gwon Ssi Chenghuabo(安東權氏成化譜: Andong Gwon Genealogy of Chenghua Era)』. By this work, we investigated the character of ruling class in the early Chosun dynasty(朝鮮王朝) period at the point of 「marriage ties」, especially 「range of entangled marriage」. Jung-Hyoun Wang Hwoo's clan, Pa-Pyoung Yun Ssi(Pa Pyoung Yun Clan: 坡平尹氏) belonged to the aristocracy since early period of Goryeo dynasty(高麗王朝). Moreover this clan was declared as one of the 「Families of the State Councilors(Chaesang-chijong: Families that the court could intermarry with: 宰相之宗)」by the Goryeo dynasty 26th King Ch′ung-son(忠宣王: 1275~1325). And Pa-Pyoung Yun clan enhanced political influence through reiterated marriages with the Royal family(王室), meritorious retainers(功臣) and distinguished family(mighty clan: 鉅族) in the early Chosun period. The two representative genealogies of Korea, 『Munhwa Liu Ssi Gajungbo』 and 『Andong Gwon Ssi Chenghuabo』contain every descendants including agnate and cognate since ancestor(progenitor). And many historical high-ranking officials throughout the late Goryeo and early Chosun period(14~16th century) are listed on the genealogies. By examining this genealogies, we can see many cases of the chain marriages between powerful families. Also we can discover consanguinity(blood relationship) and human network between Jung-Hyoun Wang Hwoo and many influential vassal(powerful courtier)-for example Jeong Chang-Son(鄭昌孫: 1402~1487) and Han Myoung-Hwoi(韓明澮: 1415~1487)-and even her mother-in-law, So-Hye Wang Hwoo(1437~1504).

Streptozotocin 유도 당뇨백서의 구강점막과 신장에서 Proliferating cell nuclear antigen 발현에 관한 연구

유정택,김경욱 단국대학교 치의학연구소 1996 논문집 Vol.8 No.1

Streptozotocin induced diabetes mellitus revealed a chronic disorder of carbohydrate, fat, and protein metabolism characterized by an absolute or relative insulin deficiency, fasting hyperglycemia, glycosuria, a striking tendency toward development of atrherosclerosis, microangiopathy, nephropathy, neuropathy, and destrution of some vital organs in body. PCNA(Proliferating Cell Nuclear Antigen) revealed DNA polymerase auxilliary factor, which was expressed on late G1 phase and early S phase in cell cycle. The purpose of this study was to assess proliferation activity and histopathologic changes of oral mucosa and kidney in experimental induced diabetic rats through hematoxylin & eosin staining and immunohistochemical staining by PCNA. The results wer obtained as follows: 1. The first week after DM induction, some vacuolized blood vessel cells of veins were seen in oral mucosa. 2. In the control group of oral mucosa, many PCNA positive cells were experssed at the basal and parabasal cell layer. 3. The third day after DM induction, PCNA positive cells were not expressed, but expressed in the fourth week, and then increased in the sixth week after DM induction. 4. In the experimental group of kidney, eosinophilic cytoplasms and ruptured capillaries in the glomerulus increased periodically. Some congestions and plasma organizations were seen in the fourth and sixth week after DM induction and hyaline materials in the proximal convoluted tubules increased in the first week after DM induction. 5. PCNA positive cells were weakly expressed on the tubule cells of kidney in the control group, but not in the whole experimental groups. From the above results, proliferating cells of oral mucosa and convoluted tubules in kidney were prevented by streptozotocin induced diabetes mellitus, but recovered periodically in oral mucosa. Destruction of glomerulus, convoluted tubules and vessels in kidney increased periodically.

산업보건관리대행 보건관리자의 업무규정 방향

유경혜 가톨릭대학 산업의학쎈타 산업의학연구소 1995 韓國의 産業醫學 Vol.34 No.3

The purpose of this study was to suggest the direction of the job description for the health professionals involved in the Group Health Service (GHS). To achieve this purpose the study was designed to compare frequencies by type of services in total responses and to compare services expected and provided by type of health professional qualifications in each job. Data were collected from 17 physicians, 46 nurses, 31 hygienists and 8 administrators taking position of management part in the 33 GHS agencies. The guidelines of the job description were based on the data results of what services were expected in the GHS according to the job of the health professionals and what services were provided by health professionals. The survey was carried out by questionnaires which were developed by literature review and consultations from the occupational health experts in each area; physician, nurse, hygienist and administrator. After pretest, the content was modified and was used as a tool for this study. Data were analysed by SAS programme in the service area and in the qualification of job performance. Descriptive statistics was used. The results showed high expectation and high performance in the categories of administrative services, service provided to employees, and expanded services in order. There was no similarity between expected services and provided services in doctors' responses. However, the responses from the nurses and hygiensts showed similarities between expected and provided services such as health management ares in nurses, and working environment management in hygiene part. Data interpretation suggested the importance of new job description of 4 different occupational health professionals according to their qualifications.

不公正貿易에 의한 産業被害救濟制度의 補完에 관한 考察

柳京得 明知大學校 經濟硏究所 1997 경영연구 Vol.16 No.1