Novel Trials to Control Harmful Algal Blooms in Seawater

Hyun?Jae Shin,Hoon Cho,Un?Sun Jin,Yun?Kyung Park,Si Wouk Kim 한국생물공학회 2010 한국생물공학회 학술대회 Vol.2010 No.10

CMOS 연산 증폭기 및 비교기 회로의 자동 설계

신현우,김천호,김득경,신창호,신경욱 國立金烏工科大學校附設生産技術硏究所 1994 産業技術開發硏究 Vol.10 No.-

The paper describes a CMOS analog circuit design tool, K_ACD(Kumoh_Analog Circuits Designer), and design results. The K_ACD was developed for automatic design of fundamental analog circuit blocks such as comparator, unbuffered OP AMP, and buffered OP AMP. For given specifications and process parameters, it computes bias currents, transistor sizes, voltage gain, and power dissipation, then SPICE simulations are automatically carried out. Some design examples show usefulness of the K_ACD in analog circuit designs.

[P8-81] Stimulatory Effects of Aqueous Extract from Cuscuta chi­nensis Lam. on the Proliferation and Differentiation of Osteoblastic MG-63 Cells

Hyun Mo Yang,Hyun一Kyung Shin,Jin-Kyung Kim 한국식품영양과학회 2007 한국식품영양과학회 학술대회발표집 Vol.2007 No.10

비만증 환자에서 한약제에 의한 체중 감소효과

Oh, Seung-Joon,Jeong, In-Kyung,Kim, Young-Seol,Choi, Young-Kil,Paeng, Jeong-Ryung,Bae, Jung-Hwan,Shin, Hyun-Dae 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Seung-Joon Oh, In-Kyung Jeong, Young-Seol Kim, Young-Kil Choi, Jeong-Ryung Paeng¹, Jung-Hwan Bae and Hyun-Dae Shin²Department of internal Medicine, College Medicine, Endocrine Research Institute¹. Department of Rehabilitation, College of Oriental Medicine², Seoul, korea. Bady Fat Reduction Effects of Red Ginseng Compound Preparation on the Patients with Obesity. Proceedings of International Symposium on East-West Medicine, Seoul. 244-254, 1999.-Obesity can be defined as a metabolic disease due to an increased state of fat tissues caused by an imbalance of calorie intake and use. Recently, in Korea by improvement and westernization of food intake, along with decrease in exercise activities, the prevalence of obesity has increased greatly. Our objectives were to study stability and effects of decrease in body fat by administering red ginseng compound preparation (known to have body fat decreasing effects in laboratory animals) to obesity patients on low calorie diets. Changes in weight and body fat were measured while carrying out calorie-restricted diets on patients for 4 weeks, then administering red ginseng compound preparation for another 4 weeks. The patients were 20 people whose BMI were 25kg/㎡ or over and whose percent body fat was also 30% or over when tested by bioelectrical conductivity. 1. Changes in weight were from 70.04kg(base line) to 67.43kg(after taking red ginseng compound preparation). 2. In similar sense, BMI decreased from 27.12kg/㎡(base line) to 26.56kg/㎡(after dieting), and further to 26.01kg/㎡ (after taking red ginseng compound preparation). The BMI seemed to decrease significantly compared to the baseline after the use of red ginseng compound. 3. Waist hip ratio was changed from 0.8858(base line) to 0.8728, but it was statistically insignificant. 4. The percent body fat was 35,16%(base line), 33.87%(after dieting), and 31.68%(after taking red ginseng compound preparation). 5. Complete blood cell count and blood chemisrty remained unaffected by the administration. 6. In concern to endocrinologic studies, T3 decreased from 118.7 to 98.2ng/dL, and T4 increased from 8.8 to 9.2㎕/ dL. Epinephrine showed a tendency to decreased from 0.27 to 0.25 ng/mL, and norepinephrine increased from 0.39 to 0.44ng/mL. 7. Leptin was not changed. 8. Some patients complained adverse effects; constipation(5 patients, may be due to diet therapy), fatigue (2 patients), pruritus(2 patients), flushing(s patients), dizziness(3 patients) and epigastric discomfort(2 patients). However their symptoms were mild, so medication did not stopped. In conclusion, loss of weight without significant side effects was observed during low calorie diet and red ginseng compound preparation administration. This is thought to be in relation to sympathetic nerve system rather than adrenal gland. Also, further long0term studies should be required, since the observed results were based on short-term changes in weight.

한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

식품신소재의 개발

신현경 中央大學校 食糧資源硏究所 1991 食糧資源硏究所 論文集 Vol.3 No.1

한국인은 곡류제품의 점진적 소비감소와 동물성식품 및 과채류의 지속적인 공급 증가에 의해서 칼슘을 제외하고 대부분의 영양소 필요량을 충족시키고 있으며 아울러 수명연장과 각종 성인병의 발생율이 높아짐에 따라서 새로운 생리적 기능 또는 기존 식품소재의 문제점을 보완할 수 있는 새로운 식품소재의 개발이 필요한 시기에 이르렀다. 식이섬유, 올리고당, 생리적 기능과 정미성 기능을 갖는 펩타이드류, 지방질 대체물, 저콜레스테롤 축산물 등 주요 식품신소재들에 대해서 자료조사를 통하여 그 기능적 특성과 소재원을 소개하였다. 또한 저자의 연구실에서 수행한 연구로서 어유로부터 eicosapentaenoic acid와 같은 기능성 고도불포화지방산의 농축 및 산화안정화 실험, 토양으로부터 분리한 Mucor sp.를 배양하여 gamma-linolenic acid의 생산에 관한 연구 및 분리균인 Geotrichum candidum을 이용한 사과향의 생합성에 관한 연구내용을 간단히 기술하였다.

비만을 동반한 위암 환자에서 두 병을 같이 수술 치료한 경험(증례)

최경현,윤기영,문형환,신연명,서경원,안수미,송윤미,석정희,정경연,이은하 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.3

Obesity is growing problem in Korea. We had a case of bariatric surgery during gastric cancer operation. Patient was 29 year old Korean lady with early gastric cancer located in the lesser curvature side of the middle 1/3 of the stomach. Her body weight was 89 kg, height 163 cm, and thus body mass index was 33.5 kg/m2. Preoperative blood pressure was 130/90 mmHg, hemoglobin 12.9 g/dL, total lymphocyte count 3,280/mL, serum albumin 4.3 g/dL, CEA 1.1 ng/mL, CA 19-9 9.1 ng/mL, and alpha fetoprotein 2 ng/mL. Another associated disease was right thyroid follicular neoplasm. The chest X-ray was normal. After IM injection of 2,500 units of heparin 30 minutes before the induction of general anesthesia, she received curative subtotal gastrectomy and Roux en Y gastrojejunostomy when a malabsorption loop of 120 cm jejunum was incorporated between the Treitz ligament and the end to side jejuno-jejunostmy site at May 29th 2006. Her postoperative course was uneventful except a minor wound seroma and the elevations of serum amylase(up to 4 folds) and lipase(up to 2 folds). She lost her body weight 9 kg in 5th, 21 kg in 7th, and 27 kg in 10th postoperative months to became 61.5 kg. On follow up exams in July 2008, she gained 4 kg to overcome her weakness and fatigue. From the above result, the incorporation of a malabsorption loop during reconstruction phase of gastric cancer operation was a good option for obese gastric cancer patients especially in cases of early gastric cancer.

알코올 및 인삼액이 효소활성도에 미치는 영향에 관한 연구

신경현,조만희,김창세 순천향대학교 1994 논문집 Vol.17 No.2

This study was investigated for the change of r-GTP, CPK activity and CPK-isoenzyme by alcohol and Ginseng administration, The normal white S.D rats were classified with four groups; ethanol treated was group A, ethanol pretreated group combined pretreated with Ginseng extract was group B, Ginseng extract treated was group C, and Ginseng extract treated group combined pretreated with ethanol was group D. The white rats of four groups were treated with 20%, 30%, 40% ethanol and/or 1% Ginseng extract. Then enzyme activities such as r-GTP, CPK and CPK-isoenzyme had been measared in serum, hepatic, and renal tissues. The sample was collected by 5 day intervalus for 25 days. The following results were obtained. 1. The changes of serum r-GTP activities were significantly increased in ethanol-treated group, decreased in Ginseng-treated group. 2. The changes of hepatic r-GTP activites were significantly increased in ethanol-treated group, decreased in Ginseng-treated group. 3. The changes of renal r-GTP activites were significantly increased in ethanol-treated group, decreased in ginseng-treated group. 4. The changes of serum CPK activites were significantly increased in ethanol-treated group, decreased in ginseng-treated group. 5. The changes of hepatic and renal tissue CPK activites were not significant. 6. The changes of serum and hepatic tissue CPK-isoengyme were significantly increased in ethanol-treated group, decreased in ginseng-treated group combined pretreated with ethanol. 7. The changes of CPK-isoengyme, CPK 1 and CPK 2 were not significant.

우수방사성의약품 생산시설 개발

신병철,정원명,박상현,이규일,박경배,박진호 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.2

Manufacturing facilities of the pharmaceuticals must meet certain level of the cleanness required so that foreign substances such as dust, moisture, heat, microorganism, or virus do not contaminate the product. In case of radiopharmaceuticals for medical treatment and diagnosis, not only should the operators and environment be protected from radiation but also need to be isolated from the foreign contaminant. Therefore, manufacturing facilities for radiopharmaceuticals must satisfy the design standards of both hot cell and clean room which are specified by GNP. However, standards of maintaining negative pressure for preventing spread of radioactive contaminant in isolated facilities conflict with the standards of maintaining positive pressure for keeping cleanness. To solve this problem, are pressure of hot cell was designed lower than in the adjacent area to meet standards of the radiation safety. To keep higher cleanness in certain part of the hot cell for filling, minimal relative positive pressure allows. In order to effectively maintain the cleanness that is required for production of Tc-99m generator, which takes 70% of whole demand of radiopharmaceuticals, the rooms placed in each side of production room are used as a buffer area and three lead hot cells are installed in production room. In this research, we established the appropriate engineered design concept for Tc-99m generator manufacturing facility, which satisfies both GMP cleanness standard for preventing particles, bacteria, other contaminants and the regulations of radiation safety for supervising and controlling the amount of radiation exposure and exhausted radioactivity. And the concept of multi-buffer zones is introduced to apply negative air pressure for hot cell with first priority and to continue relative positive air pressure for clean room.

욕실 연구방향 제시를 위한 경향 분석 : 국내 학회지논문과 학위논문을 중심으로

신경주;황윤정;문서현 한양대학교 2009 韓國 生活 科學 硏究 Vol.29 No.1

The purpose of this study in order to present a study direction on the bathroom which is growing in the importance of life viewpoint, surveyed the changes according to the study method (survey method, survey objects, the number of objects) and the study skill by the year and the study area - first centering on the theses related to academic theses and dissertations publicized until now - and tried to present a systematic study direction on the bathroom, which would be required in future through categorization. The methods of the study was to collect data related to the journals and theses study and to analyze 115 papers. The data were processed by SPSS PC+ windows version 15.0 program and were analyzed using the frequencies analysis, crosstabulation analysis, and Cluster Analysis are implemented. The results are as follows. It needs repeated research of lifestyle through a changed bathing way by a change of time. And through this research it needs to investigate the actual conditions of present bathrooms. It was thought that the various study methods, including an emotional study method using image or color as well as sentence through the web surfing using the internet in addition to using the existing methods, are needed. The survey method is important in the number of the survey objects as the quantitative study, but it was also thought that the qualitative study, including field observation, focus group interview and interview in depth, has to go abreast appropriately in order to variously accept the opinions of residents. In addition to the development of new study area, a reanalysis plan through the extraction • synthesis of data studied so far has to be conducted because the basic direction was presented. The study on psychology and behavior of children and students, which have not been treated in the survey objects, in addition to adults, housewives, the aged, and the disabled, has to be conducted together. The study on the regulations related to heating and soundproofing, in addition to water supply • draining facilities, ventilation and construction, has to be gone abreast. We sincerely hope that this study is anticipated to be used for the material to present a study direction in order to arrange more systematically the bathroom study.