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        전경대원에서 발생한 결핵의 임상 양상

        문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

        Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

      • 비만 여성을 대상으로 한 해조류 추출물의 국부처치와 운동 병행을 통한 지방분해 효과의 임상적 검정

        서태수,이인숙,변재철,김규호,박승한,김유영,김상국,김현정,김상기,신동철,성미영,박종석,김종기,박언휘 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.3

        This study was carried out to test the body fat breakdown during topical seaweed extract treatment and in combination with the aerobic exercise. Of 20 female obesity subjects, ten treated a cream types of seaweed extract(control group) and ten treated a placebo cream(placebo group). Topical treatment of each sample was designed for 4 weeks, and treated with 2 times a day about 10ml on the abdomen and the thigh, respectively. All subjects were participated aerobic dance half hour a day and four times a week. After 4 weeks of topical treatment and exercise, they were measured body fat, skinfold thickness, body circumference. Then venous blood samples were taken and analyzed blood cells, serum enzymes, and serum lipids. There were reduction of body weight, % of body fat, antebrachium, brachium, chest, waist, thigh circumference and abdomen thickness between pre and post treatment in both group. Especially, body weight and % of body fat significantly reduced in the subjects treating the seaweed extract than those treating the placebo. There were significant decrement in total cholesterol and LDL whereas increment in HDL and TBIL in the control group, but no significant difference in the placebo group. In conclusion, there were 7.6% of body fat reduction during 4 weeks of aerobic exercise and 21% of body fat reducement in combination of topical seaweed treatment and exercise, respectively. These results suggest that the topical treatment of seaweed extract should be very effective for fat breakdown. Especially, the body fat breakdown maximized in the combination with the topical seaweed extracts treatment and the aerobic exercise.

      • 비호지킨 림프종의 임상적 고찰

        김태원,조은택,조기섭,정재용,허재봉,장영,박유환,정춘해 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

        A retrospective clinical and histologic study of 30 non-Hodgkin's lymphomas diagnosed at the Department of Hemato-oncology of the Chosun University from January 1989 to December 1993 is presented. Among total 30 cases whose sexes were mentioned, male were 18 and female were 12 and the ratio is 1.5:1. The peak incidence of non-Hodgkin's lymphoma was found in the third decade. The case distributions by Working formulation were summarized in table 3. The most common histopathologic type of non-Hodgkin's lymphoma was the diffuse large cell type of intermediate grade. The presenting symptoms at the time of first visit to the hospital were summarized in table 4. The most common symptoms were palpable mass. Lymph node enlargements were found in 87 %, and most frequently on cervical area(35%). The incidence of primary nodal lymphoma is more frequent than extranodal lymphoma, 1.2:1. The most common primary site of extranodal lymphoma is the gastrointestinal tract. In the laboratory findings, the data of hemoglobin and hematocrit were summarized in table 8, 9, Values of hemoglobin and hematocrit of female patients greater than those of male patients. The results of the immunophenotypings of nodal and extranodal lymphoma indicates that the B-cell lymphoma are predominant(B:T=1.4:1). The clinical stage was Ⅱ in 9 cases(30%) Ⅲ in 9 cases(30%), Ⅳ in 8 cases(26.7%), Ⅰin 4 cases(13.3%), 28 cases were treated with CHOP regimen. Among them, 17 cases(60.8%) achieved a complete remission. 5 cases had a partial response. The most frequent toxicities were toxic hepatitis.

      • 삼각법을 기반으로한 구조화된 격자 캘리브레이션

        김은석,주기세,왕지남 한국경영과학회 2002 한국경영과학회 학술대회논문집 Vol.- No.1(1)

        Many sensors such as a structured grid pattern generator, a laser, and CCD camera to information have been used, but most of algorithms for a calibration are inefficient memory and experiment data are required. In this paper, the calibration algorithm of a structured grid pattern based on triang is introduced to calculate 3D information in the real world. The beams generated from str pattern generator established horizontally with the CCD camera are projected on the calibr CCD camera observes the intersection plane of a light and an object plane. The 3D infor calculated using observed and calibration data. This proposed method in this paper has advantages such as a memory saving and an e experimental data since the 3D information are obtained simply triangulation method.

      • 한국어 문장분석을 위한 의미사전의 설계 및 구현

        김은희,양기철 木浦大學校 情報産業硏究所 1995 情報産業硏究誌 Vol.3 No.-

        Preexisting lexicon for korean parsing has been built mainly based on syntactic information. However, Precise parsing of Korean sentence is difficult only with syntactic information, since korean is a partially free word-order which has frequent elimination of necessary constituents. Hence, including semantic information in the lexicon is essential in order to increase the quality of parsing. In this thesis, a prototype semantic lexicon for korean parsing is implemented. The components of the semantic lexicon are set of concepts, conceptual catalogues, conceptual relation, and a type hierarchy.

      • 모래여과에 의한 하수처리 유출수의 인제거 특성에 관한 연구

        김환기,이성백,신은섭 全北大學校 附設 都市및環境硏究所 1998 都市 및 環境硏究 Vol.13 No.1

        Phosphate remaining in wastewater treatment must be removed for the conservation of water quality in a water system. The concentration of phosphate can be decreased from a physic-chemical method for the discharge water of a sewage disposal plant. In this study, it was performed to examine the adsorptive characteristics of sand filter through batch and column experiments in saturated soil. Batch experiment evaluates the concentration change of phosphate with retention time and column experiment performs to analyze a breakthrough curve for phosphate adsorption. And the batch experiment result of adsorptive equilibrium was fitted for the Langmuir model and the Freundlich model. The results obtained from this study were summarized as follows; 1. In the batch experiment, the adsorptive capacity of PO_4^-3 by sand was below 47% of adsorption rate for retention 24 hours in the range of initial concentration 2.0㎎/ℓ ∼4.6㎎/ℓ. 2. The Langmuir and the Freundlich models on the adsorptive equilibrium were fitted well to both in a good correlation coefficient. 3. In the column experiment, the adsorptive breakthrough curve for input PO_4^-3(15.0㎎/ℓ) occurred to about 30ℓ. And output concentration was almost decided at initial breakthrough curve.

      • 스토리지로부터의 멀티미디어 데이타 실시간 회수에 관한 연구

        김은기 大田産業大學校 1996 한밭대학교 논문집 Vol.13 No.0201

        Multimedia data are composed of several media data that have their own error characteristics. They have temporal and spatial relations. To support these characteristics, ⅰ) Each media data should be transmitted and managed separately and collectively, ⅱ) Data should be transmitted within a specified time limit, ⅲ) Each media data that exists for the same length in time axis should be transmitted concurrently, ⅳ) Not only temporal relations, but also spatial relations should be transmitted during the data transfer phase, ⅴ) Appropriate error recovery mechanisms should be applied separately according to each media. We have designed a transport protocol which support realtime transmission of multimedia data Our transport protocol is characterized as follows. ⅰ) It supports realtime transmissions f multimedia data that have stream input and stream output. ⅱ) The temporal and spatial relations of multimedia data are transmitted to the receiver using a separate channel. ⅲ) Appropriate error recovery mechanisms are applied separately according to each media. In particular, the transmission methods of spatial and temporal relation is graceful. And the error recovery mechanism is favorable in the multimedia communication

      • SCOPUSKCI등재

        CT 스캔 영상재구성과 개인용 컴퓨터를 이용한 영상 재형성과의 비교에 관한 연구

        김상준,김은경,정기훈 大韓口腔顎顔面 放射線學會 1994 Imaging Science in Dentistry Vol.24 No.2

        Radiographic planning is needed for implant placement in order to determine implant length, jaw bone volume, anatomical stucture nd so on. Radiographic examination includes conventional radiography, conventional tomography and CT scan. The most accurate mesurement can be obtained from CT scan. For the cross-sectional view of mandible, CT scan reconstruction is generally needed. But the cross-sectional view of mandible can be reformed by personal computer. This study was performed to examine the clinical usefulness of reformed image using personal computer in comparison with CT scan reconstructed image. CT axial slices of 4 mandibles of 4 volunteers were used. Digital imaging system was composed of Macintosh Ⅱ ci computer, high resolution Sony XC-77 CCD camera, QuickCapture frame grabber board and "NIH Image" program. Seven reconstructed cross-sectional images within CT machine(CT group) were obtained. And seven reformed cross-sectional images(PC group) after digitization of CT axial slices into the personal computer were obtained. PC group was compared with CT group in the objective and subjective aspects. The results were as follow: 1.Measurement of mandibular height & width in both group showed insignificant difference(p>0.05). 2.Subjective assessment of the mandibular canal in both group showed insignificant difference(p>0.05). 3.Image reformation using personal computer could provide panoramic view, which could not be obtained in CT scan reconstruction.

      • 고양이 심장에서 관상동맥 결찰과 재관류로 인한 ATPase 변화에 관한 세포화학적 연구

        김은기,류임주,엄창섭,서영석 고려대학교 의과대학 1991 고려대 의대 잡지 Vol.28 No.1

        To understand the behaviors of Ca^(++)-ATPase and Na^(+)-K^(+) ATPase in ischemic and ischemic-reperfused heart, and to elucidate their roles in those conditions, the authors observed cat myocardium ultracytochemically. Acute ischemia was induced by ligation of the anterior interventricular branch of left coronary artery. Reperfusion was begun after 20minutes of ischemia and discontinued after 1-2 minutes when ventricular fibrillation appeared on EKG. The reaction products of Ca^(++)-ATPase were irregular In shape, and distributed mainly in myocytes in the vicinity of capillaries. In normal cardiac myocytes, they were present at plasmalemma, sarcoplasmic reticulum, transverse tubules, intercalated discs including intermediate junctions, desmosomes and gap junctions. Some were scattered along with inner mitochondrial membranes and myofibrils. After 20 minutes of ischemia. almost all structures had negligible reaction products. except some dilated sarcoplasmic reticulum beneath the plasmalemma, which retained strong reactivities. After reperfusion, the reaction products showed a tendency to be Increased. But there was hardly any reaction products in mitochondria. Patches of myofibrils with much increased enzyme activity than other myofibrils were found scattered. In addition, macrophages showed strong reactivity throughout their nuclei. Endothelial cell nuclei, however, were free of reactions in all conditions. The reaction products of Na^(+)-K^(+) ATPase were fine In nature. In normal cardiac myocytes, they were present at plasmalemma, transverse tubules, sarcoplasmic reticulum, various structures of intercalated discs, myofibrils, mitochondria, inner nuclear membranes and heterochrormatin. In ischemic heart, the reactions decreased generally and increased after reperfusion. Mitochondria in normal states had many fine reaction products scattered throughout them to the degree of masking their details. In ischemic conditions, the reaction products, decreased in number, were located contiguous to inner mitochondrial membrane. After reperfusion each reaction product was increased in size, although the amount was less than normal conditions. Gap junctions were unique structures'in that they lacked reactivity both in ischemic and ischemic-reperfused conditions. Other structures of the intercalated discs, especially desmesomes, showed increased reactions. Some myofibrils showed much strong reactions in ischemic and ischemic-reperfused groups, even though the reactivity at myofibrils as a whole was decreased. Under all conditions, the nuclei of interstitial cails and endothelial cells had their reaction products related to the nuclear membranes and heterochrormatin. The authors, based on the above observations, conclude that Ca^(++)-ATPase may have little role in ischemic and ischemic-reperfused conditions. Na^(+)-K^(+) ATPase during reperfusion, however, even depressed in their activities, may try to normalize the decreased intramitochondrial ATP contents and the increased intracellular Na^(+) concentrations resulted from ischemic conditions.

      • 딸기 와인 개발을 위한 최적 발효 조건

        김민기, 박미성, 엄은경, 조은혜, 이종수 배재대학교 자연과학연구소 2016 自然科學論文集 Vol.27 No.1

        Optimal fermentation condition for development of new strawberry wine were investigated. Commercial yeast, Fermivin was good for brewing of strawberry wine and its optimal addition concentration was also 1%. Maximal ethanol content of strawberry wine was obtained when raw strawberry juice(24 brix) was fermented by 1% Fermivin at 25℃ for 7 days and its antioxidant activity was 78.5%. 새로운 딸기 와인을 개발하기 위한 최적 발효조건을 연구하였다. 시판효모인 페미빈이 딸기와인 제조에 제일 좋았고 1%가 최적 첨가 농도이었다. 딸기와인의 최대 에탄올 생성량은 생딸기주스 (24brix)를 1% 페미빈으로 25℃에서 7일 발효시켰을 때 얻어졌고 이 발효액의 항산화활성은 78.5% 이었다.

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