아토피 피부염 치료 처방에 대한 方劑學的 考察

이상현,윤용갑 한국전통의학연구소 2006 한국전통의학지 Vol.15 No.1

In Oriental Medicine, Atopic dermatitis(AD) belongs to the category of the Naesun(奶癬), Taesun(胎癬), Taeryumchang(胎斂瘡), Eczema(濕疹), Seupchang(濕瘡) Samanpung(四彎風), Chimumchang(浸淫瘡). The Basic Prescriptions which have been used for treatment of Atopic dermatitis are saengryusamultang(生料四物湯), Onchungeum(溫淸飮), Seungmagalgeuntang(升麻葛根湯), Hoichunryangkyuksan(回春凉膈散), Doghengsan(導赤散), Pyungweesan(平胃散), Heungbangpaedoksan(荊防敗毒散), Goomigangharltang(九味羌活湯), Baekhotang(百虎湯), Gaegytang(桂枝湯), Yukmigihyuangtang(六味地黃湯). AD can divide three groups, Acute-Type, Semiacute-Type, Chronic-Type, according to it's condition. This study shows that it can be applicate Seungmagalgeuntang(升麻葛根湯), Hoichunryangkyuksan(回春凉膈散), Doghengsan(導赤散), Heungbangpaedoksan(荊防敗毒散), Goomigangharltang(九味羌活湯), Baekhotang(百虎湯), Gaegytang(桂枝湯) for treatment of Acute-Type, Pyungweesan(平胃散) for treatment of Semiacute-Type, and saengryusamu1tang(生料四物湯), Onchungeum(溫淸飮) for treatment of Chronic-Type.

Anti-leukenic effects of GIPESAN and it`s components on HL-60 cells

Yong Gab Yun 한의병리학회 2004 대한동의병리학회 학술대회논문집 Vol.2004 No.8

加味黃連地黃湯의 비만인 체중, 혈청 지질에 미치는 영향

윤용갑,류도곤,정선관,윤치근,정헌택,이호섭 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.1

We investigated the effects of Gamihwangryunjihwangtang on serum total cholesterol, high density lipoprotein, triglyceride, GOT, GPT and body weight. Body weight and trunk fat decreased significantly. These results suggest that the effect of Gamihwangryunjihwangtang related to the decrease of body fat. Key word : gamihwangryunjihwangtang, serum total cholesterol, GOT, GPT, body weight,

슬립모델을 이용한 변형률의존 유형변형 탄소성재료의 구성방정식 개발

남용윤(Yong-Yun Nam),김사수(Sa-Soo Kim),이상갑(Sang-Gab Lee) 한국해양대학교 해사산업연구소 1996 海事産業硏究所論文集 Vol.5 No.-

최근들어 안전하고 합리적인 구조를 설계하기 위하여 구조물의 내충돌 또는 내충격에 대한 요구와 관심이 높아지고 있는데, 이러한 문제들은 아주 짧은 시간동안에 대변형이 일어나는 비선형문제라는 특징이 있다. 구조재료는 변형속도가 빨라짐에 따라 정적인 범주에서 보이는 거동과는 달리 변형률의존적인 거동을 보인다. 따라서 대변형 소성문제인 충돌해석 등에는 종래 사용하여 온 변형률 비의존 재료구성 방정식으로는 한계가 있다. 이 논문에서는 이러한 점을 개선하기 위하여 연강의 소성거동을 잘 나타낼 수 있는 소성슬립모델을 채용하고, 비선형경화를 도입하여 변형도 적용범위를 확장한 대변형 탄소성 변형률의존 재료구성 방정식을 제시하였다. 본 구성방정식의 특징으로 항복조건과 하중조건이 필요없기 때문에 계산이 간편하며, 전위밀도와 속도로써 소성을 표현하기 때문에 보다 물리적인 의미를 가지고 금속재료의 소성 현상을 나타낼 수 있다. The advanced development in many fields of engineering and science has caused many interests and demands fer crashworthiness and non-linear dynamic transient analysis of structure response. Crash and impact problems have a dominant characteristic of large deformation for short time scales with material plasticity. The structural material shows rate-dependent behaviors in those cases. Conventional rate-independent constitutive equations used in the general purposed finite analysis programs are inadequate for dynamic finite strain problems. In this paper, a rate-dependent constitutive equation for elastic-plastic material is developed. The plastic stretch rate is modeled based on slip model with dislocation velocity and its density so that there is no yielding condition, and no loading conditions. Non-linear hardening rule is also introduced for finite strain. Material constants of present constitutive equation are determined by experimental data of mild steel, and the constitutive equation is applied to uniaxile tension loading.

A Rate-Dependent Elastic Plastic Constitutive Equation in Finite Deformation Based on a Slip Model

남용윤(Yong-Yun Nam),김사수(Sa-Soo Kim),이상갑(Sang-Gab Lee) 대한조선학회 1997 大韓造船學會 論文集 Vol.34 No.1

소성스핀의 발생기구에 대한 연구

남용윤(Yong-Yun Nam),김사수(Sa-Soo Kim),이상갑(Sang-Gab Lee) 한국해양대학교 해사산업연구소 1996 海事産業硏究所論文集 Vol.5 No.-

지금까지 소성스핀은 내부응력(역응력)에 의한 재료의 이방성에서 유래한다고 알려져 왔다. 소성스핀은 역응력의 객관성률에 적용되어 왔고, 또한 Jaumann률을 사용할 때 단순전단에서 해가 요동하는데 이에 대한 한 해결책으로도 사용되어 왔다. 그러나 소성스핀의 발생 원인에 기본적인 잘못이 있다고 사료된다. 본 연구에서는 결정 재료의 소성변형을 고찰하고 종래와는 다른 소성스핀 발생기구를 제시한다. 소성변형에 대한 재료의 기하학적인 특성과 2가지 이상의 응력성분이 동시에 작용해야 소성스핀은 발생한다. 그러므로 종래에 알려진 바와 달리 소성스핀은 특별한 경우를 제외하고는 미미하고, 초기의 재료직조(texture)에 민감하다. It has been proposed that plastic spin originates from material anisotropy such as internal stress. The plastic spin has been applied to the objective rates of back stresses and used as the cure for the oscillation of solution in pure shear with Jaumann rate. However, there have been likely to be some fundamental misleadings in the origin of plastic spin. In this paper, plastic deformations of polycrstalline materials are discussed in detail, and new origins for plastic spin are suggested in which it originates from geometric properties of plastic deformation and from the simultaneous stress components. It is also shown that the plastic spin is not significant and is sensitive to initially given texture.

Therapeutic Effects of Schizandra chinensis Fruit on DSS-Induced Colitis

LEE Young-Mi,KIM Dae-Ki,YUN Yong-Gab,LEE Ji-Eun,TAE Jin,KANG Chon-Sik 대한약학회 2006 大韓藥學會 總會 및 學術大會 Vol.2006 No.2

아토피 피부염 치료 처방에 대한 방제학적(方劑學的) 고찰(考察)

이상현,윤용갑,Lee, Sang-Hyun,Yun, Yong-Gab 대한한방안이비인후피부과학회 2006 한방안이비인후피부과학회지 Vol.19 No.3

In Oriental Medicine, Atopic dermatitis(AD) belongs to the category of the Naseun, Taesun(胎癬), Taeryumchang(胎斂瘡), Eczema(濕疹), Seupchang(濕瘡), Samanpung(四彎風), Chimumchang(浸淫瘡). The Basic Prescriptions which have been used for treatment of Atopic dermatitis are saengryusamultang(生料四物湯), Onchungeum(溫淸飮), Seungmagalgeuntang(升麻葛根湯),Hoichunryangkyuksan(回春凉膈散), Doghengsan(導赤散), Pyungweesan(平胃散), Heungbangpaedoksan(荊防敗毒散), Goomigangharltang(九味羌活湯), Baekhotang(白虎湯), Gaegytang(桂枝湯), Yukmigihyuangtang(六味地黃湯). AD can divide three groups, Acute-Type, Semiacute-Type, Chronic-Type, according to it's condition. This study shows that it can be applicate Seungmagalgeuntang(升麻葛根湯), Hoichunryangkyuksan(回春凉膈散), Doghengsan(導赤散), Heungbangpaedoksan(荊防敗毒散), Goomigangharltang(九味羌活湯), Baekhotang(白虎湯), Gaegytang(桂枝湯) for treatment of Acute-Type, Pyungweesan(平胃散) for treatment of Semiacute-Type, and saengryusamultang(生料四物湯), Oncungeum(溫淸飮) for treatment fo Chronic-Type.

숙지황, 부자 전탕액이 고혈압 백서의 혈압에 미치는 영향

류도곤 ( Do Gon Ryu ),윤용갑 ( Yong Gab Yun ),노진구 ( Jin Goo No ),이호섭 ( Ho Sub Lee ) 대한경락경혈학회 2001 Korean Journal of Acupuncture Vol.18 No.1

한의학에 있어서 음양의 조절은 매우 중요하다. 숙지황은 음허를 치료하는 주약이며, 부자는 양허를 치료하는 주약이다. 한의학에서 신성고혈압의 발생은 음허와 관련이 있다고 하였다. 본 연구는 실험적 신성고혈압과 자연발증고혈압 백서에 숙지황과 부자 전탕액을 투여 후 혈압의 변동과 혈장 renin 활성도, aldosterone 및 심방이뇨호르몬 (atrial natriuretic hormone)의 변동을 관찰하였다. 숙지황 투여후 실험적 신성고혈압 백서의 혈압은 감소하였다. 부자 전탕액 투여 후 자연발증고혈압 백서의 혈압 상승이 억제되었다. 숙지황 및 부자 전탕액 투여 후 자연발증고혈압 백서의 혈장 renin 활성도는 감소하였다. 부자 전탕액 투여 후 신성고혈압 백서의 혈장 ANP 농도는 감소하였다. 부자 전탕액의 혈압강하 작용은 ANP 및 aldosterone 농도의 변동과 관련이 있다고 사료된다.

고령자 담석증의 임상적 고찰

차상우(Sang Woo Cha),천갑진(Gab Jin Chun),박용순(Yong Soon Park),송동화(Dong Hwa Song),조영덕(Young Deok Cho),김진오(Jin Oh Kim),봉형근(Hyung Keun Bong),조주영(Joo Young Cho),김연수(Yun Soo Kim),이준성(Joon Seong Lee),이문성(Moon Sun 대한소화기학회 1996 대한소화기학회지 Vol.28 No.2

N/A Background/Aims: Gallstone is uncommon before adolescence, and its incidence increases v:ith age. In elderly patients, one of the important characteristics of the ga]lstone disease is that they often have bile duct stones causing acute obstructive cholangitis. Another is that they could be accompained by other diseases. Methods: We analyzed 2,154 patients surgical]y or radiologically proven gallstone patients at the Soon Chun Hyang University Hospita] from l984 to 1994 and compared the clinical characteristics of elderly patients group(over 60 years) with younger patients group(under 60 years). Results: The peak incidence of gallstone (fisease wos noted in the 6th decade and the mean age was 55 years. Elderly patients group were 40.6%(874 cases) and younger patients group were 59.4%(l,280 cases'). Male to female ratio of eler]y patients vras I:1.IO. The location of stones was gallbladder(GB) in l,395 cases(64.9%), multiple sites in 416 cases(19.3%), common bile duct(CBD) in 214 cases(9.9%) and intrahepatic duct(IHD) in 129 cases(5.9%). In elderly patients group, the ]ocation of stones was multiple sites in l86 cases(2l.3%)and CBD in 120 cases(l3.7%). Frequency of stones in multiple sites and GB was significontly higher in elderly patients group than younger patients group(pO.OJ). The prominent clinical manifestations were right upper quadrant abdominal pain(24.5%), epigastric pain(19.4%), and no symptoms(l0.8%). In elderly patients group, chilling and jaundice were significantly higher than younger patients group(p 0.01). The associated diseases were cardiac diseases(l3.7%), diabetes me]litus(8.1%), malignancy (7.3%), liver cirrhosis(6.4%), and hepatitis(5.2%). Cardiac diseases, respiratory diseases, diabetes rnellitus and malignancy were more frequently associated in elder]y patients group than in younger group(p0.01). The incidence of complication was 10.7%(230/2,154)and mortality rate was 1.1% (24/2,154). In elderly patients group, the incidence of complication* and mortality* was signifi- cantly higher than younger patients group(*: p0.01; **: p0.05). Conclusions: The incidence of stones in CBD and mutiple sites, complication and morta]ity rate were higher, and chilling and jaundice were more frequently noted in elderly patients group than younger patients group. Our results suggest that ear]y diagnosis and proper treatment migbt be necessary in elderly patients with the gallstone disease. (Korean J Gastroenterol 1996; 28:260-266)