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Yun, Hui-Jun,Park, Jong-Man,Jeon, Chan Woo,Nam, Sang Yong,Shin, Sung-Chul,Hwang, Jaeyoung,Kim, Yun-Hi American Scientific Publishers 2014 Journal of Nanoscience and Nanotechnology Vol.14 No.8
<P>A new poly(octathiophene) based copolymer was designed and synthesized by the palladium catalyzed Suzuki coupling reaction. The structure of the newly obtained copolymer was confirmed by 1H-NMR and IR. The number-average molecular weight (M(n)) of the polymer was 36,000 with a poly-dispersity index of 1.15. The polymer has good solubility in common solvents such as chloroform, toluene, chlorobenzene, dichlorobenzene and tetrahydrofuran at room temperature. The optical, thermal and electrochemical properties of the polymer were characterized by UV-vis absorption, TGA and DSC and cyclovoltametry, respectively. A thin film transistor using the new polymer as an organic semiconductor was found to exhibit typical p-channel FET characteristics with a hole mobility of 5 x 10(-4) cm2/Vs.</P>
( Hui Jung Kim ),( Kang Suk Ko ),( Sang Bae Park ),( Hyeong Il Kim ),( Yang Tong Cho ),( Woong Ji Kim ),( Byung Jun Jeon ),( Hye Min Yu ),( Min Ju Song ),( Yun Kyung Hong ),( Wan Hee Yoo ) 전북대학교 의과학연구소 2007 全北醫大論文集 Vol.31 No.2
Vascular thrombosis in the venous or arterial system is quite common in systemic lupus erythematosus(SLE), especially in patients who have active disease with vasculitis and antiphospholipid antibodies(aPL). These thrombotic events usually developed on deep veins of the lower extremities and very rarely occur on the upper extremities. The upper extremity deep vein thrombosis(UEDVT) is a relatively rare disease, constituting about 2% of all cases of deep venous thrombosis, and usually occurs axially and subclavian vein. Here, we report an unusual case of brachial and basilica vein thrombosis in a 34-yr-old woman with SLE after taking oral contraceptives for 3months before the onset of upper-extremity deep vein thrombosis(UEDVT). Venous Doppler ultrasonography and CT images showed thrombosis and thrombophlebeitis of the brachial and basilica vein of the left arm. Thrombophilia work-up including IgM and IgG anticardiolipin antibodies, lupus anticoagulant were negative. Protein C, Protein S, and antithrombin 3 levels were within normal range. The patient was started anticoagulation therapy and oral contraceptives were discontinued. After that, she was asymptomatic and she had been treated with aspirin 100mg/day.
Four Consecutive Recurrent Abortions in Patient with Essential Thrombocythemia
Hui-Gyeong Seo,Hye-Na Park,Hye-Ji Jeon,Yun-Sook Kim 순천향대학교 순천향의학연구소 2017 Journal of Soonchunhyang Medical Science Vol.23 No.1
Essential thrombocythemia (ET) is characterized by most cases in which platelet counts exceed 1 million/μL. ET is usually no symptoms during non-pregnancy, but arterial and venous thrombosis and hemorrhage may develop in pregnancy. Pregnancy in these patients is associated with many complications in both pregnant women and fetuses such as recurrent abortion, intrauterine fetal growth restriction, preterm delivery, preeclampsia, and stillbirth. In these patients, aspirin, low-molecular-weight heparin (LMWH), and interferon alpha (INF-α) are recommended during pregnancy. We report a case of four consecutive abortions despite being treated with INF-α, low dose aspirin, and LMWH in patient with ET.
Age-Related Changes in Sulfur Amino Acid Metabolism in Male C57BL/6 Mice
Jeon, Jang Su,Oh, Jeong-Ja,Kwak, Hui Chan,Yun, Hwi-yeol,Kim, Hyoung Chin,Kim, Young-Mi,Oh, Soo Jin,Kim, Sang Kyum The Korean Society of Applied Pharmacology 2018 Biomolecules & Therapeutics(구 응용약물학회지) Vol.26 No.2
Alterations in sulfur amino acid metabolism are associated with an increased risk of a number of common late-life diseases, which raises the possibility that metabolism of sulfur amino acids may change with age. The present study was conducted to understand the age-related changes in hepatic metabolism of sulfur amino acids in 2-, 6-, 18- and 30-month-old male C57BL/6 mice. For this purpose, metabolite profiling of sulfur amino acids from methionine to taurine or glutathione (GSH) was performed. The levels of sulfur amino acids and their metabolites were not significantly different among 2-, 6- and 18-month-old mice, except for plasma GSH and hepatic homocysteine. Plasma total GSH and hepatic total homocysteine levels were significantly higher in 2-month-old mice than those in the other age groups. In contrast, 30-month-old mice exhibited increased hepatic methionine and cysteine, compared with all other groups, but decreased hepatic S-adenosylmethionine (SAM), S-adenosylhomocysteine and homocysteine, relative to 2-month-old mice. No differences in hepatic reduced GSH, GSH disulfide, or taurine were observed. The hepatic changes in homocysteine and cysteine may be attributed to upregulation of cystathionine ${\beta}-synthase$ and down-regulation of ${\gamma}-glutamylcysteine$ ligase in the aged mice. The elevation of hepatic cysteine levels may be involved in the maintenance of hepatic GSH levels. The opposite changes of methionine and SAM suggest that the regulatory role of SAM in hepatic sulfur amino acid metabolism may be impaired in 30-month-old mice.
전진희 ( Jeon Jin Hui ),윤숙정 ( Yun Sug Jeong ),김성진 ( Kim Seong Jin ),이승철 ( Lee Seung Cheol ),원영호 ( Won Yeong Ho ) 대한피부과학회 2004 대한피부과학회지 Vol.42 No.1
Eruptive vellus hair cysts are characterized by asymptomatic, skin colored to bluish, of brownish, 1-4㎜ sized, follicular papules and nodules located on mainly anterior chest, axilla, groin, and thigh. Histopathologic examination reveals cysts containing multiple vellus hairs and the laminated keratinous materials at dermis. We reported 2 cases of eruptive vellus hair cysts developed on the unusual sites, forehead and buttock, respectively. (Korean J Dermatol 2004;42(1):74~76)