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      • KCI등재

        Influences of Three Oidiodendron maius Isolates and Two Inorganic Nitrogen Sources on the Growth of Rhododendron kanehirae

        Lei-Chen Lin,Wan-Rou Lin,Yu-Chen Hsu,Hung-Yu Pan 한국원예학회 2020 원예과학기술지 Vol.38 No.5

        Rhododendron kanehirae Wilson is an endemic species of Taiwan that is listed as extinct in the wild by the Red List of Vascular Plants of Taiwan. R. kanehirae seedlings can form mycorrhizae with the ericoid mycobiont Oidiodendron maius. A completely randomized experimental design was conducted to investigate the effects of three different O. maius isolates (strains CBS110450, RhYM3, and RooDK1) as well as nitrate and ammonium (inorganic nitrogen) on the growth of R. kanehirae by evaluating height and shoot, root, and total fresh weight. Three isolates of O. maius showed different colony morphology and growth rate, which was further verified by molecular analysis. The results showed that application of ammonium fertilizer improved the height and shoot, root, and total fresh weight of all of the R. kanehirae seedlings. Among them, seedlings inoculated with RhYM3 had the highest fresh weights and heights. By applying an appropriate amount of nitrogen combined with RhYM3 inoculation, the rhizome of R. kanehirae grew well. The information provided here is crucial for the conservation of R. kanehirae, as this species is on the verge of extinction.

      • KCI등재

        Transcriptional activation of insulin-like growth factor binding protein 6 by 17β-estradiol in SaOS-2 cells

        Yu-yan Zhao,Lei Guo,Xiao-juan Zhao,Hong Liu,Tian Lei,Dong-jie Ma,Xiao-yu Gao 생화학분자생물학회 2009 Experimental and molecular medicine Vol.41 No.7

        Osteoblasts can synthesize the insulin-like growth factors (IGFs) and the IGF-binding proteins (IGFBPs), which may either enhance or attenuate IGF-stimulated bone cell proliferation. Since estrogen induced osteoblastic differentiation and proliferation through an estrogen- responsive gene in target cells, we investigated the effects of estrogen on IGFBP-6 expression in the human osteoblastic-like cell line SaOS-2. Expressions of IGFBP-6 protein and mRNA increased 2.8 and 2-fold, respectively, in the presence of 17-β-estradiol (E2) (0.01 to 1 μM) and estrogen receptor (ER) in SaOS-2 cells. On the other hand, E2 induced a 2-fold increase in SaOS-2 cell proliferation. To identify genomic sequences associated with estrogen responsiveness, the 5'-promoter region (-44 to +118) of the IGFBP-6 gene was cloned into a chloramphenicol acetyltransferase (CAT) reporter vector. E2 induced a 3-fold increase in CAT activity in SaOS-2 cells transiently transfected with this construct. Identification of the estrogen- responsive element (ERE) [5'-CCTTCA CCTG-3'] (-9 to +1) in this IGFBP-6 gene promoter region was confirmed using electromobility shift assays and deletion analysis. This functional ERE was important for E2-induced trans-activation of the IGFBP-6 gene. These results demonstrate that E2 exhibits a positive effect on IGFBP-6 gene transcription through estrogen- liganded ER binding to the functional ERE in the IGFBP-6 gene promoter in SaOS-2 cells. Osteoblasts can synthesize the insulin-like growth factors (IGFs) and the IGF-binding proteins (IGFBPs), which may either enhance or attenuate IGF-stimulated bone cell proliferation. Since estrogen induced osteoblastic differentiation and proliferation through an estrogen- responsive gene in target cells, we investigated the effects of estrogen on IGFBP-6 expression in the human osteoblastic-like cell line SaOS-2. Expressions of IGFBP-6 protein and mRNA increased 2.8 and 2-fold, respectively, in the presence of 17-β-estradiol (E2) (0.01 to 1 μM) and estrogen receptor (ER) in SaOS-2 cells. On the other hand, E2 induced a 2-fold increase in SaOS-2 cell proliferation. To identify genomic sequences associated with estrogen responsiveness, the 5'-promoter region (-44 to +118) of the IGFBP-6 gene was cloned into a chloramphenicol acetyltransferase (CAT) reporter vector. E2 induced a 3-fold increase in CAT activity in SaOS-2 cells transiently transfected with this construct. Identification of the estrogen- responsive element (ERE) [5'-CCTTCA CCTG-3'] (-9 to +1) in this IGFBP-6 gene promoter region was confirmed using electromobility shift assays and deletion analysis. This functional ERE was important for E2-induced trans-activation of the IGFBP-6 gene. These results demonstrate that E2 exhibits a positive effect on IGFBP-6 gene transcription through estrogen- liganded ER binding to the functional ERE in the IGFBP-6 gene promoter in SaOS-2 cells.

      • Pretreatment Thrombocytosis as a Prognostic Factor in Women with Gynecologic Malignancies: a Meta-analysis

        Yu, Min,Liu, Lei,Zhang, Bing-Lan,Chen, Qi,Ma, Xue-Lei,Wu, Yu-Ke,Liang, Chun-Shui,Niu, Zhi-Min,Qin, Xin,Niu, Ting Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12

        Background: This study was performed to analyze the prognostic implications of pretreatment or preoperative thrombocytosis in women with gynecologic malignancies. Material and Methods: We surveyed 2 medical databases, PubMed and EMBASE, to identified all relevant studies. A total of 14 (n=3,490) that evaluated the link between thrombocytosis and 5-year survival were included. REVMAN version 5.1 was used for our analysis and publication bias was evaluated using the Begg's funnel plot and tested by STATA 11.0. Risk ratios (RRs) with 95% confidence intervals (CIs) generated by the random effect model were used to assess the strength of any association. Results: 709(20.3%) of the 3,490 patients exhibited thrombocytosis (platelet counts > $400{\times}10^9/L$) at primary diagnosis, and their mortality was 1.62-fold higher compared with the others (RR=1.62, 95%CI=[1.28-2.05], p<0.0001). Thrombocytosis failed to have a stronger effect on the survival of advanced patients of stages III to IV in our study (n=478, RR=1.29, 95% CI=[1.13-1.48], p=0.0003), nor in women with cervical cancer in stage IB (n=1371, RR=1.73, 95% CI=[1.71-2.58], p=0.007). In addition, when adjusted for different carcinoma, it was associated with worse prognosis for all except the ones with vulvar cancer (n=201, RR=0.43, 95% CI=[0.14-1.29], p=0.13). Conclusions: This meta-analysis indicated that thrombocytosis might be associated with a worse prognosis for patients with gynecologic malignancies but without specificity or sensitivity for the ones in advanced stage. When adjusted for different gynecologic malignancies, it showed a significant effect on survival of all except vulvar cancers.

      • KCI등재

        中国商业银行流动性风险的决定要因

        Lei Yu,Yu Kwanghyun,Bang Sungchul 아시아유럽미래학회 2013 유라시아연구 Vol.10 No.1

        2006년 WTO가입을 계기로 중국의 은행 보험산업의 개방이 확대되면서 많은 외자은행들이 중국에 진출하게 되었다. 이에 따라 많은 중국 상업은행들은 치열한 경쟁 속에서 살아남기 위해 유동성 을 포기하는 대가로 수익성을 추구하는 사례가 종종 나타나고 있다. 또한 2007년 미국 서브프라임 모기 지 사태로 촉발된 유동성 리스크로 인해 많은 은행들과 금융기업들이 파산하게 되었으며 이는 글로벌 실물경제에 큰 영향을 미쳤다. 1978년 중국공산당 11기 3중 전회를 통해 개혁 개방 정책을 선언한 이후 중국 정부가 경제개혁 기간 에 은행산업의 개혁을 추진함으로써 은행산업의 독점 국면이 점차 타파하게 되며 경쟁 시스템을 도입하 게 되었다. 아시아 금융위기 무렵에 중국 은행산업에 과대경쟁으로 유동성 위기가 발생하게 되었으며 국 유은행인 하이난발전은행(Hainan Development Bank)이 유동성 고갈로 파산하게 되었다. 이로 말미암 아 중국인민은행(People's Bank of China: PBC)이 약 40억 위안 손실을 입혀 중국 은행산업에 매우 큰 영향을 미쳤다. 또한, 중국은 장기적으로 무역지수 흑자와 대량 외국자본 유입의 까닭으로 은행산업에 유동성 과잉 (excess liquidity) 현상이 나타났다. 이러한 유동성 과잉 상황은 단기적으로는 시장 금리(inter-bank rate)가 은행 예금 금리보다 더 낮아지는 금리 역전현상이 나타나고 은행은 아무리 수익성이 높은 투자 를 할지라도 바닥을 볼 것이며, 장기적으로는 부실채권의 누적이 가속화되어 자산 거품을 유발할 수 있 으며 최종 외부의 충격으로 자산의 거품은 사라지고 상업은행의 유동성 위기가 초래될 수 있다(노진호 & 이승준, 2009). 게다가 유동성 과잉으로 말미암아 은행들 간에 과대 경쟁의 현상을 유발하며 신용 리 스크와 이자율 리스크를 동반한 유동성 리스크를 촉발할 가능성도 높아진다. 한편, 중국은 한국의 최대 교역국으로서 한국 경제에 영향을 미치는 중요변수 중 하나다. 그러나 한국 의 경우 중국 은행 보험산업에 잠복해 있는 다양한 불확실성으로 인해 발생할 수 있는 유동성 리스크에 대한 인식 정도는 매우 부족한 편이다. 이러한 상황에서 중국 상업은행들의 유동성 위기는 중국 경제에 대한 의존도가 높은 한국에 큰 영향을 줄 수 있으며, 특히 이미 중국에 투자한 한국기업들과 지속적으로 중국 전역으로 확장을 시도하는 글로벌 금융회사들에게 직접적 영향을 미칠 수 있다. 따라서 본 연구는 중국 상업은행의 유동성 리스크에 영향을 미치는 내부적 요인과 거시 경제 요인을 실증분석하고, 은행의 자산규모별로 어떤 차이가 있는지를 분석해보고자 한다. 이를 위해 국제 은행 통 계사이트인 BankScope의 데이터, 중국인민은행의 자료 그리고 중국 통계연보(China Statistical Yearbook)를 활용하여 홍콩, 마카오, 타이완 등 지역을 제외하며 중국 국유상업은행(State-owned Commercial Bank), 주식제상업은행(Joint-stock Commercial Bank) 그리고 도시상업은행(Urban Commercial Bank)을 포함한 25개 중국 상업은행을 대상으로 추정한다. 횡단면자료의 이분산과 시계열 자료의 자기상관 문제로 발생하는 분산의 과소평가 문제로 인하여 패널OLS 추정방법을 사용하는 것을 타당하지 않다. 그러나 본 연구는 고정효과모형(fixed effects)모형 및 확률효과(random effects)모형과 비교하는 차원에서 먼저 패널OLS로 추정한 결과를 제시하며, 그 후 Hausman 검정에 따라 고정효과모 형과 확률효과모형을 동시에 추정하여 효율적인 모형을 위주로 분석하였다. 실증분석결과, 첫째 고정효과모형으로 25개 상업은행의 유동성을 추정한 경우, 부실채권 비율(NPL), 요구불예금 대총 예금 비율(CURRENT), 자기자본수익률(ROE), 자기자본비율(CAR) 등 은행 내부적 요소는 중국 상업은행의 유동성에 영향을 미치지 않는 반면, 명목 이자율(R), 광의통화 변동률(M2), 소비자 물가지수(CPI) 등 거시적 결정요인들이 은행의 유동성에 (-)효과가 나타났다. 이는 중국에서 인민 은행이 통화정책을 활용하여 중국 상업은행의 유동성을 조정하고 유동성 리스크를 통제할 수 있다는 것 으로 해석된다. 둘째, 총자산 규모가 1조 위안을 기준으로 대행은행과 중소형은행을 구분하여 확률효과모형을 추정하 였다. 따라서 대형상업은행의 유동성은 요구불 예금 대 총 예금의 비율(CURRENT), 자기자본수익률 (ROE)와 같은 은행 내부의 요소와 명목 이자율(R), 광의통화 변동률(M2), 소비자 물가지수(CPI), 2008 금융위기(CRISIS) 등 거시적 경제요인의 영향을 받을 반면, 중소형 상업은행의 경우, 부실채권 비율 (NPL), 명목 이자율(R), 광의통화 변동률(M2) 등 요소들이 상업은행의 유동성에 마이너스(-)효과가 있음을 보여준다. 즉, 은행 내부의 요소와 거시적 경제요인이 중국 대형 상업은행의 유동성에 영향을 미 치나 중소형 상업은행의 유동성에 부실채권, 거시적 경제요소를 영향을 받는 것으로 추정되었다. With China’s accession to the World Trade Organization (WTO), many foreign banks have started to enter into China while Chinese banking and insurance industries have been deepening and opening up. Commercial banks will pay more attention to profit and abandon appropriate liquidity in order to survive in fierce competition. Particularly in recent years, liquidity risk caused by the US sub-prime mortgage crisis has lead banks and many financial institutions to collapse and has also been bringing the devastating impact on the global economy. In 1978, Chinese government began to implement the reform and opening up, and in the meanwhile began to reform the banking sector, which interrupted the banking monopoly and led in competition system into banking sector. During the Asian financial crisis in 1997, China’s banking sector experienced liquidity crises due to over competition, leading to the bankruptcy of Hainan Development Bank because of exhausted liquidity. The bankruptcy of Hainan Development Bank resulted in the loss of nearly 4 billion yuan of People’s Bank of China, which had a graveness influence on China’s banking sector. In addition, China’s long-term trade surplus and a large inflow of foreign capital lead to the excess liquidity in the banking sector. In the pressure of such excess liquidity, banks will blindly decrease lending rates to get inter-bank rate lower than bank-deposit rate appearing interest rate inversion phenomenon to decrease bank returns. In the long term, this will probably accelerate the accumulation of non-performing loan of bank. When the economy changes, asset bubbles of bank will quickly be shattered, which will directly result in the systematic financial crisis in the banking sector. Meanwhile, China as a largest trading partner of South Korea has been a key factor on its economy. However, South Korea is lacking of understanding of potential various uncertainties and liquidity risk in China’s Economy, which bases on banking. In this case, South Korea will be significantly influenced due to its highly dependence on China’s Economy if Chinese commercial banks suffer from liquidity risk. Especially, Korean companies already invested in China and global financial companies constantly attempting to expand all over of China should be directly affected. Therefore, this paper is to analyze the determinants of the bank’s liquidity risk in Chinese commercial banks and what difference between large commercial banks and small-medium commercial banks. The banking data used in this paper were extracted from the database BankScope IBCA-Fitch, the People’s Bank of China and China Statistical Yearbook. We used panel data of 25 commercial banks over the period from 2004 to 2011 to estimate the determinants of liquidity risk by panel OLS, the fixed effects and random effects regression. The results of the empirical analysis are as follows: first, internal factors in banks did not affect the liquidity of the commercial banks in China, but it was affected by macro-economic factors negatively. It implies that the People’s Bank of China will be able to adjust liquidity and manage liquidity risk in commercial banks in China using monetary policy. Second, in terms of asset size of banks, both internal factors in banks and macro-economic factors have influence on the liquidity of large commercial banks in China, however, small-medium commercial banks have only been affected by non-performance loans ratio and macro-economic factors.

      • KCI등재

        Improved Work Function of Preferentially Oriented Indium Oxide Films Induced by the Plasma Exposure Technique

        Lei Yang,Shuai Guo,Qiuling Yang,Yuankun Zhu,Bing Dai,Hailing Yu,Pei Lei,Jiecai Han,Ying Hou,Jiaqi Zhu 대한금속·재료학회 2015 ELECTRONIC MATERIALS LETTERS Vol.11 No.6

        The preferentially oriented In2O3 thin films were prepared on glass substrates by conventional magnetron sputtering with Ar+ plasma exposure at room temperature. Based on the x-ray diffraction, x-ray photoelectron spectroscopy, and UV photoelectron spectroscopy results, it was found that the Ar+ plasma exposure not only enhanced the low-temperature crystallization of In2O3 thin films, but also led to a dramatic improvement in the work function. Furthermore, it demonstrated that the shift mechanism of the work function in In2O3 thin films mainly combined with theelimination of oxygen defects and the change of the preferential orientation of In2O3 film surface.

      • KCI등재

        Clustering and Recommendation for Semantic Web Service in Time Series

        ( Yu Lei ),( Wang Zhili ),( Meng Luoming ),( Qiu Xuesong ) 한국인터넷정보학회 2014 KSII Transactions on Internet and Information Syst Vol.8 No.8

        Promoted by cloud technology and new websites, plenty and variety of Web services are emerging in the Internet. Meanwhile some Web services become outdated even obsolete due to new versions, and a normal phenomenon is that some services work well only with other services of older versions. These laggard or improper services are lowering the performance of the composite service they involved in. In addition, using current technology to identify proper semantic services for a composite service is time-consuming and inaccurate. Thus, we proposed a clustering method and a recommendation method to deal with these problems. Clustering technology is used to classify semantic services according to their topics, functionality and other aspects from plenty of services. Recommendation technology is used to predict the possible preference of a composite service, and recommend possible component services to the composite service according to the history information of invocations and similar composite services. The experiments show that our clustering method with the help of Ontology and TF/IDF technology is more accurate than others, and our recommendation method has less average error than others in the series of missing rate.

      • Synthesis and densification of ultra-fine ZrC powders-effects of C/Zr ratio

        Yu, Lei,Feng, Lun,Lee, Hyung Ik,Silvestroni, Laura,Sciti, Diletta,Woo, Yi Jin,Lee, Sea-Hoon Elsevier 2019 International journal of refractory metals & hard Vol.81 No.-

        <P><B>Abstract</B></P> <P>The excess carbon and oxygen contents of ZrC nano-powders was controlled, and the resultant effects on the densification of ZrC was analyzed. The particle size of the synthesized ZrC powder was about 200 nm and its oxygen content was 0.49 wt%. The good results can be attributed to the rapid heating and cooling rate, the beneficial effects of current, and the relatively low synthesis temperature by using SPS (Spark plasma sintering) for the powder synthesis. The homogeneous distribution between reactants was an important factor to minimize the formation of excess carbon. With increasing the amount of carbon in the raw powder mixture, the oxygen content of ZrC powders decreased and the densification was suppressed. The decrease of excess carbon content, the presence of oxygen in the ZrC lattice, and the fine particle size promoted the sintering of ZrC ceramics without any additives at relatively low temperature and pressure (1750 °C, 40 MPa).</P> <P><B>Highlights</B></P> <P> <UL> <LI> Ultra-fine ZrC powders were synthesized using a spark plasma sintering apparatus. </LI> <LI> ZrC powder with particle size of 200 nm and oxygen content of 0. 49 wt% was obtained. </LI> <LI> The powder can be densified without additives at low temperature and pressure. </LI> <LI> Low carbon content, and the oxygen in the lattice were benefit for the densification. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

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