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Prenatally detected thoracic neuroblastoma
( Yejin Park ),( Hyun Jin Lee ),( Yun Ji Jung ),( Joon Ho Lee ),( Ja Young Kwon ),( Young-han Kim ) 대한산부인과학회 2018 Obstetrics & Gynecology Science Vol.61 No.2
Neuroblastoma is the most common pediatric extracranial solid tumor derived from primitive neural crest cells of the sympathetic nervous system. Although one-fifths of all neuroblastomas occurs within the thorax, thoracic neuroblastomas detected in fetus have been rarely reported. We report a case of fetal thoracic neuroblastoma with massive pleural effusion detected with prenatal ultrasonography. A 34-year-old Korean second-gravida was referred to our hospital at 30 weeks of gestation for evaluation, after the right lung mass found in the fetus. Approximately 3 cm, well-defined, hyperechoic mass was found in the right thorax with right pleural effusion, with the initial suspicion of teratoma. However, as mass continued to grow with deteriorating pleural effusion and fetal hydrops, the mass was considered malignant after 3 weeks. After a cesarean delivery, an approximately 4 cm mass with peripheral calcification and hemothorax was found on neonatal ultrasonography. Neuroblastoma was diagnosed on excision biopsy.
Clinical Significance of Emerging Eclampsia Distinct from Preeclampsia
( Yejin Park ),( Yun Ji Jung ),( Ja Young Kwon ),( Joonho Lee ),( Young-han Kim ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-
Objective: Eclampsia refers to the development of new-onset seizures or coma in preeclampsia, as the severe end of its spectrum. The Objective of this study was to investigate clinical characteristics of emerging eclampsia on the spectrum of preeclampsia. Methods: 24 patients manifested eclamptic seizure between January 2007 and July 2018 were compared with 240 of preeclamptic patients in Severance Hospital. Clinical characteristics including maternal age, gestational age at delivery, systolic and diastolic blood pressure, gravidity, pre-pregnancy body mass index, and maternal complication such as HELLP syndrome (Hemolysis, Elevated Liver enzymes, Low Platelets), placental abruption, and neurologic sequelae were compared between eclampsia and preeclampsia followed by comparison of maternal laboratory findings. Moreover, clinical characteristics of eclampsia were analyzed depending on the onset time of eclamptic seizure-before and after labor. Results: Approximately 2.5% of eclampsia was emerged in preeclampsia. Eclamptic patients showed significantly younger (30.73.8 vs. 33.15.0, P=0.008), lower body mass index (20.733.54 vs. 22.604.44, P=0.046) and higher blood pressure (systolic: 178.4±22.0 vs. 151.3±2.0, P<0.0001; diastolic: 109.9±18.8 vs. 96.4±10.0, P<0.0001), especially during seizure episode. Furthermore, higher risks of HELLP syndrome and neurologic sequelae was accompanied with eclampsia (18.2% vs. 5.4%, P=0.043, 13% vs 0%, P<0.0001). Higher risk of eclampsia was accompanied with hyperuricemia (12.8% vs. 1.9%, P=0.001), despite no significant correlation with HELLP syndrome and placental abruption. Conclusion: Eclampsia had significant differences in clinical manifestation distinct from preeclampsia and our results suggested that higher serum uric acid level, higher risk of eclampsia. Moreover, physicians should concern the probability of eclampsia if high diastolic blood pressure continues after delivery.
( Yejin Park ),( Erang Im ) 대한주산의학회 2019 Perinatology Vol.30 No.1
Vaginal stenosis, or gynetresia, commonly results from a congenital defect, while acquired gynetresia is a rare condition. Reported contributors to acquired gynetresia include chronic graft-versus-host reaction, radiotherapy for gynecologic malignancies, female genital mutilation, postpartum foreign body insertion, or chemical insertion. We report a case of postpartum gynetresia, that was attributed to neither a foreign body nor chemicals. A 33-year-old Korean primigravid woman was referred to our hospital in hypovolemic shock due to postpartum bleeding caused by an actively bleeding vaginal laceration identified on pelvic examination. Primary repair of the vaginal laceration followed by embolization were performed. Four weeks later, postpartum gynetresia was identified on the pelvic examination. Adhesiolysis by blunt finger dissection was performed and a vaginal mold was inserted along with vaginal estrogen capsules. The vaginal mucosa was healed in four weeks.
Park, Jae Yun,Kang, Yi Young,Yoon, Hyun Woo,Park, No Kyun,Jo, Yejin,Jeong, Sunho,Won, Jong Chan,Kim, Yun Ho Elsevier 2018 Composites science and technology Vol.159 No.-
<P><B>Abstract</B></P> <P>In this study, a polystyrene-block-polyisoprene-block-polystyrene (SIS) based dielectric paste was fabricated using barium titanate (BT) as dielectric filler in order to produce organic-inorganic composites for 3D dispenser printing applications. Since a high loading of inorganic filler is generally required to obtain high dielectric properties, the surface of BT was modified with two different phosphonic acids having functional groups resembling the groups contained in the block copolymer, in order to achieve a high compatibility between the filler and the polymer matrix. Upon incorporation of 80 wt% of BT in SIS, the dielectric constant was found to be approximately 3 times higher than that of bare SIS. The surface modification of the filler enhanced its dispersion within the polymer matrix, as confirmed by the surface morphology of the composite film at a high filler content. The desired viscoelasticity was achieved through the fine-tuning of the total solid content, and consequently, the potential application of the composite as 3D printable paste was demonstrated through the formation of a layer-by-layer printed structure on a flexible substrate.</P>
Yejin Park,Jungmin Um,Subeen Hong,Yujin Han,김재희 한국통계학회 2022 응용통계연구 Vol.35 No.4
회사는 영리 등의 공동 목표를 달성하는 조직으로, 더 나은 성과를 도출해내기 위해 함께 노력하는 수많은 개인으로 구성된 사회 집단이다. 이에 따라 개인의 의사소통 능력을 비롯한 구성원 간의 네트워크 형성이 중요해지고 있다. 이러한 배경으로부터 본 연구는 직원 간 조언 관계 형성에 어떠한 요인이 영향을 미치는지 알아보고자 수행되었다. 이를 위해 미국과 유럽에 지사를 둔 컨설팅 회사 내 직원 44명의 네트워크 데이터를 ERGM (Exponential Random Graph Model) 방법으로 분석하였다. 분석 결과로 첫째, 연결을 비롯해 네트워크의 구조와 관련한 변수들이 유의하였다. 둘째, 서로 조언을 구할 확률에 성별 속성이 가장 큰 주효과로 나타났다. 셋째, 지역별 동질성은 성별 주효과보다 더 큰 연결 확률을 유도하였다. 이러한 결과로부터 직장 내 네트워크가 조금 더 효율적으로 활발하게 이루어질 수 있는 방법을 제시하였다.
Preeclampsia Increases the Incidence of Postpartum Cerebrovascular Disease in Korean Population
Park, Yejin,Cho, Geum Joon,Kim, Log Young,Lee, Tae-Seon,Oh, Min-Jeong,Kim, Young-Han KOREAN ACADEMY OF MEDICAL SCIENCE 2018 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.33 No.6
<P><B>Background</B></P><P>Multiple studies have been reported regarding preeclampsia as a possible risk factor of cerebrovascular disease (CVD). However, the correlation of preeclampsia and CVD, whether it is a cause-effect relationship or they are sharing common predisposing condition, is not well understood. Therefore, the aim of this study was to investigate the association between the preeclampsia during pregnancy and development of postpartum CVD.</P><P><B>Methods</B></P><P>A total of 1,384,550 Korean women who had a delivery between January 1, 2010 and December 31, 2012, were enrolled. Women with the risk of CVD within 1 year prior to pregnancy were excluded based on the Charlson comorbidity index. Primary endpoint was the event of CVD within a year from delivery. After exclusion, 1,075,061 women were analyzed.</P><P><B>Results</B></P><P>During the follow-up of 1 year postpartum, there were 25,577 preeclampsia out of 1,072,041 women without postpartum CVD (2.39%), and 121 of 3,020 women with postpartum CVD had preeclampsia before delivery (4.01%). In multivariate logistic regression analysis, women who had preeclampsia during pregnancy showed a higher risk for postpartum CVD (odds ratio, 1.64; 95% confidence interval, 1.37–1.98).</P><P><B>Conclusion</B></P><P>The incidence of CVD after delivery was higher in women who had preeclampsia during pregnancy.</P>
Park Yejin,Park Seongchul,Shin Juhyang,임만호 대한화학회 2022 Bulletin of the Korean Chemical Society Vol.43 No.4
The dynamics of photoexcited chlorobenzene (PhCl) and 4-fluoroiodobenzne (4- FPhI) in CCl4 were investigated using time-resolved infrared spectroscopy. When excited at 267 nm, 50% (70%) of the excited PhCl (4-FPhI) dissociates the Cl (I) atom immediately, and the remaining molecules relax into the T1 state via intersystem crossing (ISC) with a time constant of 70–80 ps. About half of the dissociated halogen atoms geminately recombine with the nascent radical with a time constant of 100–150 ps, reducing the number of generated radicals that are available to react with other reaction partners. The remaining radicals also recombine with the dissociated halogen atom on a timescale of tens of nanoseconds. Interestingly, the ISC of the light Cl-atom-involved PhCl was as efficient as that of the heavy I-atom-involved 4-FPhI. Detailed photoexcitation dynamic studies of PhCl and 4-FPhI can be utilized to understand the reaction dynamics of Ph and its derivatives.