Feature Point Extraction in Face Image by Neural Network

Yasuyuki Takahashi,Stephen Karungaru,Minoru Fukumi,Norio Akamatsu 제어로봇시스템학회 2006 제어로봇시스템학회 국제학술대회 논문집 Vol.2006 No.10

Noise Control of Sanyo Shinkansen

Yasuyuki TANAKA,Ryoichi TAKAHASHI,Tetsuo TAMADA 한국소음진동공학회 2003 한국소음진동공학회 국제학술대회논문집 Vol.2003 No.8

The relationship between positive peritoneal cytology and the prognosis of patients with FIGO stage I/II uterine cervical cancer

Shiho Kuji,Yasuyuki Hirashima,Satomi Komeda,Aki Tanaka,Masakazu Abe,Nobutaka Takahashi,Munetaka Takekuma 대한부인종양학회 2014 Journal of Gynecologic Oncology Vol.25 No.2

Objective: The purpose of this study was to assess whether peritoneal cytology has prognostic significance in uterine cervical cancer. Methods: Peritoneal cytology was obtained in 228 patients with carcinoma of the uterine cervix (International Federation of Gynecology and Obstetrics [FIGO] stages IB1-IIB) between October 2002 and August 2010. All patients were negative for intraperitoneal disease at the time of their radical hysterectomy. The pathological features and clinical prognosis of cases of positive peritoneal cytology were examined retrospectively. Results: Peritoneal cytology was positive in 9 patients (3.9%). Of these patients, 3/139 (2.2%) had squamous cell carcinoma and 6/89 (6.7%) had adenocarcinoma or adenosquamous carcinoma. One of the 3 patients with squamous cell carcinoma who had positive cytology had a recurrence at the vaginal stump 21 months after radical hysterectomy. All of the 6 patients with adenocarcinoma or adenosquamous carcinoma had disease recurrence during the follow-up period: 3 with peritoneal dissemination and 2 with lymph node metastases. There were significant differences in recurrence-free survival and overall survival between the peritoneal cytology-negative and cytology-positive groups (log-rank p<0.001). Multivariate analysis of prognosis in cervical cancer revealed that peritoneal cytology (p=0.029) and histological type (p=0.004) were independent prognostic factors. Conclusion: Positive peritoneal cytology may be associated with a poor prognosis in adenocarcinoma or adenosquamous carcinoma of the uterine cervix. Therefore, the results of peritoneal cytology must be considered in postoperative treatment planning.

Preliminary Analysis of Interconnect Full Open Faults using TEG chips

Toshiyuki Tsutsumi,Yasuyuki Kariya,Masaki Hashizume,Hiroyuki Yotsuyanagi,Koji Yamazaki,Yoshinobu Higami,Hiroshi Takahashi,Yuzo Takamatsu 대한전자공학회 2009 ITC-CSCC :International Technical Conference on Ci Vol.2009 No.7

As LSIs are scale-down, there is an increasing need to take measures against open faults. However, no practical model for open faults exists at present. Therefore, we fabricated Test Element Group (TEG) chips that intentionally incorporated full (complete) open defects and electrically measured the output signals relevant to its defective lines in order to create a new model for open fault behavior. This study reveals the effect boundary of adjacent signal lines on the line containing the full open defect for the first time using the TEG chips.

Application of Matrix Thinking Method to Introduction Program in Engineering Education

Satoh, Yasuta,Kubota, Shusuke,Takahashi, Koji,Takahata, Yasuyuki,Kim, Yun-Hae Korean Society for Engineering Education 2010 공학교육연구 Vol.13 No.2

From a lot of survey, it is obvious that most students in universities lose their desire for learning just after entering their universities. In order to solve this problem, we developed a novel educational tool for the students, named "The thinking method based on matrix diagram". If they try hard with the help of this tool, they will be able to learn how to design and manage their splendid university lives in addition to get the basic knowledge and to improve their basic abilities. It is also found that they can earn the shared knowledge mutually after learning a common method, which supports to make them to improve their communication abilities drastically.

Platinum sensitivity and non-cross-resistance of cisplatin analogue with cisplatin in recurrent cervical cancer

Munetaka Takekuma,Shiho Kuji,Aki Tanaka,Nobutaka Takahashi,Masakazu Abe,Yasuyuki Hirashima 대한부인종양학회 2015 Journal of Gynecologic Oncology Vol.26 No.3

Objective: The concept of platinum sensitivity and cross-resistance among platinum agents are widely known in the management of recurrent ovarian cancer. The aim of this study was to evaluate two hypotheses regarding the validity of the concept of platinum sensitivity and non-cross-resistance of cisplatin analogue with cisplatin in recurrent cervical cancer. Methods: In this retrospective study, the clinical data of patients with recurrent cervical cancer, who had a history of receiving cisplatin based chemotherapy (including concurrent chemoradiotherapy [CCRT] with cisplatin) and who received second-line chemotherapy at the time of recurrence between April 2004 and July 2012 were reviewed. Results: In total, 49 patients―34 squamous cell carcinomas (69.4%) and 15 non-squamous cell carcinomas (30.6%)―were enrolled. The median age was 53 years (range, 26 to 79 years). Univariate and multivariate analysis showed that a platinum free interval (PFI) of 12 months has a strong relationship with the response rate to second-line chemotherapy. Upon multivariate analysis of survival after second-line platinum-based chemotherapy, a PFI of 12 months significantly influenced both progression-free survival (hazard ratio [HR], 0.349; 95% confidence interval [CI], 0.140 to 0.871; p=0.024) and overall survival (HR, 0.322; 95% CI, 0.123 to 0.842; p=0.021). In patients with a PFI of less than 6 months, the difference of progression-free survival between patients with re-administration of cisplatin (3.0 months) and administration of cisplatin analogue (7.2 months) as second-line chemotherapy was statistically significant (p=0.049, log-rank test). Conclusion: The concept of platinum sensitivity could be applied to recurrent cervical cancer and there is a possibility of noncross- resistance of cisplatin analogue with cisplatin.

A Novel Technique of Hand-Sewn Purse-String Suturing by Double Ligation Method (DLM) for Intracorporeal Circular Esophagojejunostomy

Yuichi Takayama,Yuji Kaneoka,Atsuyuki Maeda,Yasuyuki Fukami,Takamasa Takahashi,Masahito Uji 대한위암학회 2019 Journal of gastric cancer Vol.19 No.3

Purpose: The optimal method for intracorporeal esophagojejunostomy remains unclearbecause a purse-string suture for fixing the anvil into the esophagus is difficult to performwith a laparoscopic approach. Therefore, this study aimed to evaluate our novel technique tofix the anvil into the esophagus. Materials and Methods: This retrospective study included 202 patients who were treatedat our institution with an intracorporeal circular esophagojejunostomy in a laparoscopyassistedtotal gastrectomy with a Roux-en-Y reconstruction (166 cases) or a laparoscopyassistedproximal gastrectomy with jejunal interposition (36 cases). After incising 3/4 ofthe esophageal wall, a hand-sewn purse-string suture was placed on the esophagus. Next,the anvil head of a circular stapler was introduced into the esophagus. Finally, the circularesophagojejunostomy was performed laparoscopically. The clinical characteristics andsurgical outcomes were evaluated and compared with those of other methods. Results: The average operation time was 200.3 minutes. The average hand-sewn pursestringsuturing time was 6.4 minutes. The overall incidence of postoperative complications(Clavien–Dindo classification grade ≥II) was 26%. The number of patients with ananastomotic leakage and stenosis at the esophagojejunostomy site were 4 (2.0%) and 12(6.0%), respectively. All patients with stenosis were successfully treated by endoscopicballoon dilatation. There was no mortality. Regarding the materials and devices for anvilfixation, only 1 absorbable thread was needed. Conclusions: Our procedure for hand-sewn purse-string suturing with the double ligationmethod is simple and safe.

A Novel Technique of Hand-Sewn Purse-String Suturing by Double Ligation Method (DLM) for Intracorporeal Circular Esophagojejunostomy

Takayama, Yuichi,Kaneoka, Yuji,Maeda, Atsuyuki,Fukami, Yasuyuki,Takahashi, Takamasa,Uji, Masahito The Korean Gastric Cancer Association 2019 Journal of gastric cancer Vol.19 No.3

Purpose: The optimal method for intracorporeal esophagojejunostomy remains unclear because a purse-string suture for fixing the anvil into the esophagus is difficult to perform with a laparoscopic approach. Therefore, this study aimed to evaluate our novel technique to fix the anvil into the esophagus. Materials and Methods: This retrospective study included 202 patients who were treated at our institution with an intracorporeal circular esophagojejunostomy in a laparoscopy-assisted total gastrectomy with a Roux-en-Y reconstruction (166 cases) or a laparoscopy-assisted proximal gastrectomy with jejunal interposition (36 cases). After incising 3/4 of the esophageal wall, a hand-sewn purse-string suture was placed on the esophagus. Next, the anvil head of a circular stapler was introduced into the esophagus. Finally, the circular esophagojejunostomy was performed laparoscopically. The clinical characteristics and surgical outcomes were evaluated and compared with those of other methods. Results: The average operation time was 200.3 minutes. The average hand-sewn purse-string suturing time was 6.4 minutes. The overall incidence of postoperative complications (Clavien-Dindo classification grade ${\geq}II$) was 26%. The number of patients with an anastomotic leakage and stenosis at the esophagojejunostomy site were 4 (2.0%) and 12 (6.0%), respectively. All patients with stenosis were successfully treated by endoscopic balloon dilatation. There was no mortality. Regarding the materials and devices for anvil fixation, only 1 absorbable thread was needed. Conclusions: Our procedure for hand-sewn purse-string suturing with the double ligation method is simple and safe.

OPTICAL-INFRARED AND HIGH-ENERGY ASTRONOMY COLLABORATION AT HIROSHIMA ASTROPHYSICAL SCIENCE CENTER

UEMURA, MAKOTO,YOSHIDA, MICHITOSHI,KAWABATA, KOJI S.,MIZUNO, TSUNEFUMI,TANAKA, YASUYUKI T.,AKITAYA, HIROSHI,UTSUMI, YOUSUKE,MORITANI, YUKI,ITOH, RYOSUKE,FUKAZAWA, YASUSHI,TAKAHASHI, HIROMITSU,OHNO, MA The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2

The Hiroshima Astrophysical Science Center (HASC) was founded in 2004 at Hiroshima University, Japan. The main mission of this institute is the observational study of various transient objects including gamma-ray bursts, supernovae, novae, cataclysmic variables, and active galactic nuclei by means of multi-wavelength observations. HASC consists of three divisions; the optical-infrared astronomy division, high-energy astronomy division, and theoretical astronomy division. HASC is operating the 1.5m optical-infrared telescope Kanata, which is dedicated to follow-up and monitoring observations of transient objects. The high-energy division is the key operation center for the Fermi gamma-ray space telescope. HASC and the high-energy astronomy group in the department of physical science at Hiroshima University are closely collaborating with each other to promote multi-wavelength time-domain astronomy. We report the recent activities of HASC and some science topics pursued by this multi-wavelength collaboration.

Quality indicators for cervical cancer care in Japan

Tomone Watanabe,Mikio Mikami,Hidetaka Katabuchi,Shingo Kato,Masanori Kaneuchi,Masahiro Takahashi,Hidekatsu Nakai,Satoru Nagase,Hitoshi Niikura,Masaki Mandai,Yasuyuki Hirashima,Hiroyuki Yanai,Wataru Ya 대한부인종양학회 2018 Journal of Gynecologic Oncology Vol.29 No.6

Objective: Choice of hysterectomy and adjuvant treatment for International Federation of Gynecology and Obstetrics (FIGO) 2009 stage II endometrioid endometrial cancer (EEC) is still controversial. Aims of this study were to evaluate survival benefits and adverse effects of different hysterectomies with or without adjuvant radiotherapy (RT), and to identify prognostic factors. Methods: The patients at 14 member hospitals of the Taiwanese Gynecologic Oncology Group from 1992 to 2013 were retrospectively investigated. Patients were divided into simple hysterectomy (SH) alone, SH with RT, radical hysterectomy (RH) alone, and RH with RT groups. Endpoints were recurrence-free survival (RFS), overall survival (OS), disease-specific survival (DSS), adverse effects and prognostic factors for survival. Results: Total of 246 patients were enrolled. The 5-year RFS, OS, DSS and recurrence rates for the entire cohort were 89.5%, 94.3%, 96.2% and 10.2%, respectively. Patients receiving RH had more adverse effects including blood loss (p<0.001), recurrent urinary tract infections (p=0.013), and leg lymphedema (p=0.038). Age over 50-year (HR=9.2; 95% confidence interval [CI], 1.2–70.9) and grade 3 histology (HR=7.28; 95% CI, 1.45–36.6) were independent predictors of OS. Grade 3 histology was an independent predictor of RFS (HR=5.13; 95% CI, 1.38–19.1) and DSS (HR=5.97; 95% CI, 1.06–58.7). Patients receiving adjuvant RT had lower locoregional recurrence (p=0.046), but no impact on survival. Conclusion: Different treatment modalities yield similar survival outcomes. Patients receiving SH with RT had lower locoregional recurrent with acceptable morbidity. Age and tumor grading remained significant predictors for survival among patients with FIGO 2009 stage II EEC. Objective: We aimed to propose a set of quality indicators (QIs) based on the clinical guidelines for cervical cancer treatment published by The Japan Society of Gynecologic Oncology, and to assess adherence to standard-of-care as an index of the quality of care for cervical cancer in Japan. Methods: A panel of clinical experts devised the QIs using a modified Delphi method. Adherence to each QI was evaluated using data from a hospital-based cancer registry of patients diagnosed in 2013, and linked with insurance claims data, between October 1, 2012, and December 31, 2014. All patients who received first-line treatment at the participating facility were included. The QI scores were communicated to participating hospitals, and additional data about the reasons for non-adherence were collected. Results: In total, 297 hospitals participated, and the care provided to 15,163 cervical cancer patients was examined using 10 measurable QIs. The adherence rate ranged from 50.0% for ‘cystoscope or proctoscope for stage IVA’ to 98.8% for ‘chemotherapy using platinum for stage IVB’. Despite the variation in care, hospitals reported clinically valid reasons for more than half of the non-adherent cases. Clinically valid reasons accounted for 75%, 90.9%, 73.4%, 44.5%, and 88.1% of presented non-adherent cases respectively. Conclusion: Our study revealed variations in pattern of care as well as an adherence to standards-of-care across Japan. Further assessment of the causes of variation and non-adherence can help identify areas where improvements are needed in patient care.