흉선종 제거후에 발생한 재생 불량성 빈혈 : 증례보고

전원선,이상철,김현정,배상병,김찬규,이남수,박노진,이규택,박성규,홍대식,박희숙,원종호 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.2

Thymoma is associated with myasthenia gravis, Pure red cell aplasia, and autoimmune diseases such as autoimmune hemolytic anemia, aplastic anemia, and hypogammaglobulinemia. It's association with aplastic anemia is rare and aplastic anemia appearing after surgical removal of thymoma is especially rare. The authors hereby report a case of aplastic anemia occuring in a patient who was diagnosed with thymoma and myasthenia gravis and had the tumor surgically removed. The patient was treated with anti-thymocyte globulin, cyclosporin, and prednisolone, and showed partial remission with hematologic improvements after 12 months.

냉각면이 있는 정방형내 이종유체의 저온거동에 관한 실험적 연구

전승배,장원택,김병철 朝鮮大學校 機械技術硏究所 2007 機械技術硏究 Vol.10 No.1

Two stratified fluids (water and spindle oil) in aspect ratio of 1 to 1 were studied experimentally with the variation of an initial temperature and a cooling surface temperature in the square cavity with a lower cooling surface. With the initial temperature being varied, a cooling surface temperature were varied. With supercooling phenomenon being processed, a latent heat was emitted. The temperature of the spindle oil was increased with the occurrence of the latent heat. In case of initial temperature was low. the supercooling phenomena were observed and continued up to the end of experimental.

NaC1 수용액과 실리콘 오일에 의한 성층유체의 저온거동에 관한 실험적 연구

장원택,전승배,김병철 朝鮮大學校 機械技術硏究所 2007 機械技術硏究 Vol.10 No.1

To study the influence of phase change of solution and fluid flow on low temperature in thermal storage, solar pond and removal of oil pollution at the sea, an experimental study was carried out in the square cavity filled with stratified fluids of silicone oil and aqueous sodium chloride. In the case of the lower cooling surface, the temperature of the system was dominated by conduction owing to the temperature and concentration fields stabilized by gravity. Liquid superheat influenced less in the lower part and the maximum density of sodium chloride became lower as the salt concentration got higher in the upper part. And the lower the initial temperature in the system the lower the temperature distributions were. When the actual liquid temperature was lower than the liquidus temperature with Ci = 15%, a supercooling phenomenon was observed But with Ci = 5% and Ci = 10% the actual liquid temperature was higher than the liquidus temperature and the temperature of upper fluid also got lower when the concentration of sodium chloride became lower. The influence of latent heat was less in the lower part and the raising ratio in temperature was higher when the initial concentration was lower in the upper part.

半夏의 修治方法에 따른 細胞毒性硏究

李秀培,金德宗,金康柱,田炳勳,禹元洪 圓光大學校 韓醫學硏究所 1993 원광한의학 Vol.3 No.1

The purpose of this study is to know the effects of Pinelliae Tuber on the cytotoxicity of human gingival fibroblasts according to brewing methods. Pinelliae Tuber was extracted by water in the state of being raw materials, prebrewing with Zingiberis Tuber and alumen. The extracted Pinelliae Tuber was applied to the cultured human gingival fibroblasts. The cytotoxic effct of Pinelliae Tuber was meaeured by MTTassay and microscopic findings. The results were as follows : 1. The cell viability of the fibroblasts by Pinelliae Tuber water extracts significantly decreased compared to control group. 2. The cell viability by the Pinelliae Tuber extracts prebrewed with Zingiberis Tuber was similiar to those of control group. 3. The cell viability by the Pinelliae Tuber extracts prebrewed with alumen slightly decreased, but was higher than those of PT group. 4. According to the microscopec findings, the number of cell count were smaller than normal in all experimental group, specially in the PT group, and showed the shrinkage of cytoplasmic process in the PT group and PA group.

건설 프로젝트 파이낸싱의 활용 방안에 관한 연구

김원용,박홍태,안장원,전용배 중앙대학교 기술과학연구소 1999 기술과학연구소 논문집 Vol.29 No.-

대형 프로젝트 수주를 위해서는 기획·관리능력뿐만 아니라 건설업체의 금융조달능력이 필요하다. 프로젝트 파이낸싱은 단일금융기법이 아닌 복합적이고, 다양한 이해당사자가 관련된 자금조달기법이므로 그 관계당사자중 한 부분의 노력만으로는 성공할 수는 없다. 정부와 금융기관이 협조를 강화하고, 특히 정부차원에서 지원정책과 규제 완화조치로 지원을 개선하는 노력이 필요하다. 이에 국내 건설업체도 프로젝트 파이낸싱의 도입을 건설 수주를 위한 하나의 수단으로만 받아들이는 오류를 피하고 국내외 건설환경을 분석·대응하는 등의 적절한 대처가 요구되며, 기술경쟁력뿐만 아니라 건설관리능력과 자금조달에 관련하여 프로젝트 파이낸싱의 필요성을 인식하고 연구하여 활용하도록 해야 한다. Receiving a major project order requires not only planning and management but financing capability of construction companies. Since project finance is multi-complex financial supply method by various parties concerned not a single supply method, it can not succeed with one part's effort. It is also necessary to reinforce the relationship between the governments and financing companies, especially the support and regulation relax policy by the governments. As such, domestic construction companies should not consider induction of project finance as a means of acceptance a construction environment in domestic and overseas. And also it is necessary to apply in the field which researched about technology competitiveness, construction management capability and financial supply.

가치공학변경제안제도의 활성화 방안에 관한 연구

이배호,전용배,안장원 중앙대학교 기술과학연구소 1997 기술과학연구소 논문집 Vol.27 No.-

우리나라의 건설산업은 국내건설시장의 전면 개방과 표준품셈제도의 단계적 폐지와 같은 새로운 환경변화에 직면하고 있으며, 이러한 상황하에서 건설산업은 사고의 혁신과 기술혁신 필요하다. 선진국에서는 이 치열한 생존경쟁에서 살아남고 국가예산절감의 한 방편으로 가치공학을 통하여 큰 성과를 거두고 있다. 본 연구에서는 국가예산의 큰 비중을 차지하고 있는 건설공사에 대해서 미국, 일본과 우리나라의 가치공학변경제안제도, 시행 절차, 공사비절감 사례 등을 비교·분석하고, 국가예산절감을 위한 한 방편으로 공공공사에 대하여 가치공학변경제안제도를 활성화 시키고 나아가서 민간공사에서도 가치공학을 적극 활용할 수 있도록 하는 방안을 제시하고자 하였으며, 5가지의 방안을 제시하였다. The construction industry in Korea is confronted with new environment such as opening market for domestic construction and withdrawing of standard unit system. Under these circumstances, the construction industry needs technology and thought innovation. The developed countries is successful through Value Engineering(VE) in order to survive in this fierce struggle for existence and save national budget. This study tries to provide the encouragement of VE change proposal system to public construction projects as well as private construction projects with comparison and analysis of USA, Japan and Korean VE change proposal system, procedure and examples of saving budgets, and provides five alternative proposals.

장방형내 저온 단일 수평 원관 주위의 동결현상에 관한 실험적 연구

정현철,윤재원,장원택,전승배,이동석,김병철 朝鮮大學校 機械技術硏究所 2007 機械技術硏究 Vol.10 No.1

An experimental study on water in a rectangular cavity with a horizontal cooling tube was carried out to investigate the flow character and thermal behavior in the system. Each experiment was performed with variation of initial temperature and cooling tube temperature. When the cooling tube temperature was -4℃, the supercooling phenomenon was observed regardless of the initial water temperature. And the case of cooling tube temperature was -6℃ with initial temperature was below 4℃, the supercooling phenomenon was also observedin the large region of the test section. When the cooling tube temperature was -10℃, the local region of supercooling phenomenon was observed during the freezing process. And the higher initial temperature was, the higher supercooling degree and the less difference of the ice thickness between upward and downward was observed. It is shown that by controllingthe supercooling phenomena and the cooling tube temperature, it would lead to an increase efficiency of ice making.

수직 냉각면이 있는 정방형내 성층유체의 열적거동에 관한 실험적 연구

정현철,윤재원,장원택,전승배,이동석,김병철 朝鮮大學校 機械技術硏究所 2007 機械技術硏究 Vol.10 No.1

This study was investigated by experimentals on the thermal behavior of stratified fluids in the square cavity with the vertical cooling surface by variation of initial temperature and cooling surface temperature and concluded as follows: 1. When the cooling surface temperature of the square cavity was -4℃. the supercooling phenomena was occurred every times regardless initial temperature of fluids and when -6℃ freezing was begun with out supercooling phenomena. 2. The higher the initial temperature was, the longer supercooling phenomena duration was, and the longer the supercooling phnomena was, the higher the temperature of the upper fluids was. 3. When the supercooling phenomena of water was occurred, the rate of temperature decrease of silicon oil was higher and when there was no supercooling phenomena, it was almost same the rate of temperature decrease.

Contribution of Lysine-containing cationic domains to thermally-induced phase transition of elastin-Like proteins and their sensitivity to different stimuli

( Won Bae Jeon ) 생화학분자생물학회(구 한국생화학분자생물학회) 2011 BMB Reports Vol.44 No.1

A series of elastin-like proteins, SKGPG[V(VKG)3VKVPG]n-(ELP1-90)WP (n=1, 2, 3, and 4), were biosynthesized based on the hydrophobic and lysine linkage domains of tropoelastin. The formation of self-assembled hydrophobic aggregates was monitored in order to determine the influence of cationic segments on phase transition properties as well as the sensitivity to changes in salt and pH. The thermal transition profiles of the proteins fused with only one or two cationic blocks (n=1 or 2) were similar to that of the counterpart ELP1-90. In contrast, diblock proteins that contain 3 and 4 cationic blocks displayed a triphasic profile and no transition, respectively. Upon increasing the salt concentration and pH, a stimulus-induced phase transition from a soluble conformation to an insoluble aggregate was observed. The effects of cationic segments on the stimuli sensitivity of cationic bimodal ELPs were interpreted in terms of their structural and molecular characteristics. [BMB reports 2011; 44(1): 22-27]

Pseudo-low Frequency Hearing Loss and Its Improvement After Treatment May Be Objective Signs of Significant Vascular Pathology in Patients With Pulsatile Tinnitus

Jeon, Hyoung Won,Kim, So Young,Choi, Byung Se,Bae, Yun Jung,Koo, Ja-Won,Song, Jae-Jin by Otology Neurotology, Inc. Image copyright © 2016 Otology & neurotology Vol.37 No.9

<P>Objective:In patients with pulsatile tinnitus (PT), physical examination such as auscultation with head position change or digital compression over the ipsilateral jugular vein provides physicians with important information. However, objective diagnosis of PT is sometimes limited because 1) audible bruit is absent on auscultation in some patients, 2) abnormal vascular structures found in radiologic evaluation is not always pathognomonic because they can be found in asymptomatic subjects as well, and 3) although an objective diagnostic tool using transcanal sound recording has recently been introduced, special equipment is needed. In this regard, recent studies that have reported ipsilateral low-frequency hearing loss (LFHL) on pure-tone audiometry (PTA) in some patients with PT, and its recovery after successful management, prompted us to conduct a retrospective observational study on the characteristics of the audiometric profile, the association between the audiometric profile and radiologic findings, and pre- and posttreatment changes in low-frequency hearing thresholds in PT patients. We tested two hypotheses: PT patients with marked vascular pathologies located close to the cochlea may show ipsilateral pseudo-LFHL (PLFHL) because of the masking effects of the PT itself, and their PLFHL may disappear if their vascular pathology is successfully managed by surgical or endovascular intervention.Study Design:Retrospective case review.Setting:Tertiary referral center.Patients:A total of 85 PT subjects who underwent both audiologic and radiologic examinations.Main Outcome Measure:All patients' pre- and posttreatment PTA thresholds and radiologic findings were analyzed. By comparing the LFHL (an ipsilateral hearing threshold greater than 10dB HL at both 250 and 500Hz or greater than 20dB HL at either 250 or 500Hz compared with the contralateral side) group and a non-LFHL group with regard to the incidence of vascular structural abnormalities, we evaluated the incidence of abnormal vascular structures in the head and neck between the LFHL and non-LFHL groups. In addition, by comparing pre- and posttreatment PTA thresholds of seven PT patients with ipsilateral LFHL, we further evaluated the changes in low-frequency hearing thresholds and their role as an objective sign for diagnosis and outcome evaluation.Results:Of 85 patients, 22 (25.9%) presented with ipsilateral LFHL. Compared with patients without this condition, patients with ipsilateral LFHL showed a significantly higher rate of abnormal vascular structure. In addition, most of the radiologic abnormalities found in the LFHL group were highly suspicious causative lesions that are responsible for the perception of PT according to the previous literature. In eight PT patients with ipsilateral LFHL who underwent both pre- and posttreatment audiograms, the average posttreatment pure-tone threshold at 250Hz showed significant improvement compared with the pretreatment threshold.Conclusion:PT patients presenting with ipsilateral LFHL have higher possibility of having a discrete vascular pathology near the cochlea on radiologic evaluation. As ipsilateral LFHL improves in most patients after treatment, LFHL in patients with PT may be PLFHL because of the masking effects of the pulsatile sound, and the changes in the low-frequency thresholds may be applicable for objective diagnosis and evaluation of the effects of the treatment.</P>