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      • KCI등재
      • KCI등재

        An Evaluation of the Effectiveness of Hyaluronidase in the Selective Nerve Root Block of Radiculopathy: A Double Blind, Controlled Clinical Trial

        고상봉,Alexander R. Vaccaro,장호진,신동영 대한척추외과학회 2015 Asian Spine Journal Vol.9 No.1

        Study Design: Prospective, double-blind, randomized controlled trial. Purpose: To determine the ability of hyaluronidase to provide longer lasting pain relief and functional improvement in patients with lumbar radiculopathy. Overview of Literature: Selective nerve root block (SNRB) is a good treatment option in lumbar radiculopathy. We studied the effectiveness of hyaluronidase when added to the traditional SNRB regimen. Methods: A sample size of 126 patients per group was necessary. A sample of 252 patients who underwent an injection procedure with or without hyaluronidase due to radiculopathy was included in this study. The patients were randomly divided into two groups: the control (C) group and the hyaluronidase (H) group. After SNRB due to radiculopathy, the visual analog scale (VAS) was compared at 2, 4, 6, 8, and 12 weeks between the two groups, and the Oswestry disability index (ODI) was compared at 12 weeks between the two groups. Results: Both groups seemed to have general improvement in VAS, but in C group, the VAS was higher than the H group 2 and 4 weeks after the surgery, and the difference in time-group change between 2 groups was statistically significant (p <0.05). ODI improved in both groups, and the difference in time-group change between 2 groups was not statistically significant (p >0.05). Conclusions: The rebound pain (the re-occurrence of pain within 2–4 weeks after injection) that occurs within 2–4 weeks after the injection of the routine regimen can be reduced when hyaluronidase is added to the routine SNRB regimen.

      • KCI등재

        The Prevalence of Lumbar Spine Facet Joint Osteoarthritis and Its Association with Low Back Pain in Selected Korean Populations

        Sangbong Ko,Alexander R. Vaccaro,Sangwook Lee,Jaekun Lee,Hojin Chang 대한정형외과학회 2014 Clinics in Orthopedic Surgery Vol.6 No.4

        Background: This study was to evaluate the association of lumbar spine facet joint osteoarthritis (LSFJOA) identified by multi-detector computed tomography (MDCT) with age and low back pain (LBP) in an adult community-based population in Korea. Methods: A sample of 472 participants (age range, 20 to 84 years) who underwent MDCT imaging for abdominal or urological lesions, not for chief complaints of LBP, were included in this study. LSFJOA based on MDCT findings was characterized using four grades of osteoarthritis of the facet joints. The prevalence of LSFJOA according to age group (below 40 years, 40–49 years, 50–59 years, 60–69 years, and above 70 years), gender, and spinal level was analyzed using chi-square tests and the association between LBP and LSFJOA adjusting for age, gender, and spine level was analyzed using multiple binary logistic regression test. Results: Eighty-three study subjects (17.58%) had LSFJOA (grade ≥ 2). The prevalence of LSFJOA was not associated with gender (p = 0.092). The prevalence of LSFJOA increased with age (p = 0.015). The highest prevalence of LSFJOA was observed at L4–5 in men (p = 0.001) and at L5–S1 in women (p = 0.003), and at L5–S1 in the overall population (p = 0.000). LSFJOA was not associated with LBP in men (p = 0.093) but was associated with LBP in women (p = 0.003), especially at L3–4 (p = 0.018) and L5–S1 (p = 0.026). Conclusions: The prevalence of LSFJOA based on the computed tomography imaging was 17.58% in the adult community Korean population. The prevalence of LSFJOA increased with age, and the highest prevalence was noted at L5–S1. LSFJOA was not associated with LBP at any spinal level and age except at L3–4 and L5–S1 in women.

      • SCIESCOPUS

        Displacements, damage measures and response spectra obtained from a synthetic accelerogram processed by causal and acausal Butterworth filters

        Gundes Bakir, Pelin,Richard, J. Vaccaro Techno-Press 2006 Structural Engineering and Mechanics, An Int'l Jou Vol.23 No.4

        The aim of this study is to investigate the reliability of strong motion records processed by causal and acausal Butterworth filters in comparison to the results obtained from a synthetic accelerogram. For this purpose, the fault parallel component of the Bolu record of the Duzce earthquake is modeled with a sum of exponentially damped sinusoidal components. Noise-free velocities and displacements are then obtained by analytically integrating the synthetic acceleration model. The analytical velocity and displacement signals are used as a standard with which to judge the validity of the signals obtained by filtering with causal and acausal filters and numerically integrating the acceleration model. The results show that the acausal filters are clearly preferable to the causal filters due to the fact that the response spectra obtained from the acausal filters match the spectra obtained from the simulated accelerogram better than that obtained by causal filters. The response spectra are independent from the order of the filters and from the method of integration (whether analytical integration after a spline fit to the synthetic accelerogram or the trapezoidal rule). The response spectra are sensitive to the chosen corner frequency of both the causal and the acausal filters and also to the inclusion of the pads. Accurate prediction of the static residual displacement (SRD) is very important for structures traversing faults in the near-fault regions. The greatest adverse effect of the high pass filters is their removal of the SRD. However, the noise-free displacements obtained by double integrating the synthetic accelerogram analytically preserve the SRD. It is thus apparent that conventional high pass filters should not be used for processing near-fault strong-motion records although they can be reliably used for far-fault records if applied acausally. The ground motion parameters such as ARIAS intensity, HUSID plots, Housner spectral intensity and the duration of strong-motion are found to be insensitive to the causality of filters.

      • KCI등재
      • KCI등재후보

        Banco do Brasil - Individual Entity Customer Satisfaction with the Digital Relationship Model

        Mattana, Fabiano,Maldaner, Luis Felipe,Vaccaro, Guilherme Luis Roeche,Mattana, Luciano World Technopolis Association 2019 World Technopolis Review Vol.8 No.2

        The main objective of this study was to investigate the customer's satisfaction level with the digital relationship model of Banco do Brasil Exclusive Business Offices situated in Rio Grande do Sul. Banco do Brasil is one of the largest Brazilian and global financial institutions and conducted a restructuring customer's relationship model since 2015, creating new specific service structures for certain segments, among them exclusive offices. This research had a qualitative step with an internal documentary analysis about the company and a semi-structured interview with manager's offices, in order to check the strategy and the foundations of business model, as well as identify perceptions and the difficulties in implementing this new structure. The quantitative step held the findings about customer satisfaction level in relation to the quality of services provided by offices, through an electronic survey based on the Servqual Scale developed by Parasuraman et al. (1988), which measures the difference between customer's expectations and perception in five dimensions: tangibility, reliability, understanding, safety and empathy. The results shown that Banco do Brasil customers' are satisfied with services offered through the digital model and the new business structure, in which is offered a humanized service together with the best technology. It was found, also, that digital probably would not replace the physical world, but they complement one another. Digital offices and physical agencies will coexist, improving value proposition delivery and better customers experience, satisfy them and build their loyalty.

      • KCI등재

        The Role of Exercise in the Alleviation of Neuropathic Pain Following Traumatic Spinal Cord Injuries: A Systematic Review and Meta-analysis

        Amirmohammad Toloui,Hamzah Adel Ramawad,Pantea Gharin,Alexander R. Vaccaro,Hamed Zarei,Mostafa Hosseini,Mahmoud Yousefifard,Vafa Rahimi-Movaghar 대한척추신경외과학회 2023 Neurospine Vol.20 No.3

        Objective: The objective of this systematic review and meta-analysis was to assess the efficacy of exercise in neuropathic pain following traumatic spinal cord injuries. Methods: The search was conducted in MEDLINE, Embase, Scopus, and Web of Science by the end of 2022. Two independent researchers included the articles based on the inclusion and exclusion criteria. A standardized mean difference was calculated for each data and they were pooled to calculate an overall effect size. To assess the heterogeneity between studies, I2 and chi-square tests were utilized. In the case of heterogeneity, meta-regression was performed to identify the potential source. Results: Fifteen preclinical studies were included. Meta-analysis demonstrated that exercise significantly improves mechanical allodynia (standardized mean difference [SMD], -1.59; 95% confidence interval [CI], -2.16 to -1.02; p < 0.001; I2 = 90.37%), thermal hyperalgesia (SMD, 1.95; 95% CI, 0.96–2.94; p < 0.001), and cold allodynia (SMD, -2.92; 95% CI, -4.4 to -1.43; p < 0.001). The improvement in mechanical allodynia is significantly more in animals with a compression model of SCI (meta-regression coefficient, -1.33; 95% CI, -1.84 to -0.57; p < 0.001) and in mild SCI (p < 0.001). Additionally, the improvement was more prominent if the training was started 7 to 8 days postinjury (coefficient, -2.54; 95% CI, -3.85 to -1.23; p < 0.001) and was continued every day (coefficient, -1.99; 95% CI, -3.07 to -0.9; p < 0.001). Likewise, voluntary exercise demonstrated a significantly more effect size (coefficient, -1.45; 95% CI, -2.67 to -0.23; p = 0.02). Conclusion: Exercise is effective in the amelioration of neuropathic pain. This effect in mechanical allodynia is more prominent if voluntary, continuous training is initiated in the subacute phase of mild SCI.

      • KCI등재후보

        Banco do Brasil – Individual Entity Customer Satisfaction with the Digital Relationship Model

        Fabiano Mattana,Luís Felipe Maldaner,Guilherme Luis Roeche Vaccaro,Luciano Mattana 세계과학도시연합 2019 World Technopolis Review Vol.8 No.2

        The main objective of this study was to investigate the customer’s satisfaction level with the digital relationship model of Banco do Brasil Exclusive Business Offices situated in Rio Grande do Sul. Banco do Brasil is one of the largest Brazilian and global financial institutions and conducted a restructuring customer’s relationship model since 2015, creating new specific service structures for certain segments, among them exclusive offices. This research had a qualitative step with an internal documentary analysis about the company and a semi-structured interview with manager’s offices, in order to check the strategy and the foundations of business model, as well as identify perceptions and the difficulties in implementing this new structure. The quantitative step held the findings about customer satisfaction level in relation to the quality of services provided by offices, through an electronic survey based on the Servqual Scale developed by Parasuraman et al. (1988), which measures the difference between customer’s expectations and perception in five dimensions: tangibility, reliability, understanding, safety and empathy. The results shown that Banco do Brasil customers´ are satisfied with services offered through the digital model and the new business structure, in which is offered a humanized service together with the best technology. It was found, also, that digital probably would not replace the physical world, but they complement one another. Digital offices and physical agencies will coexist, improving value proposition delivery and better customers experience, satisfy them and build their loyalty.

      • KCI등재

        Green solvent-processed complementary-like inverters based on ambipolar organic thin-film transistors

        Minjeong Lee,윤승재,Dongil Ho,Taeshik Earmme,Assunta Marrocchi,Luigi Vaccaro,김충익 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.105 No.-

        In the trends of ever-growing worldwide interest for the environment/health and the corresponding legalregulations, there have been various studies to replace toxic halogenated/aromatic hydrocarbon organicsolvents commonly used in the solution-processing of organic semiconductors (OSCs) with more sustainablegreen solvents. In this paper, we fabricated ambipolar organic thin-film transistors (OTFTs) andcomplementary-like inverters by blending a p-type OSC (6,13-bis(triisopropylsilylethynyl)pentacene;TIPS-pentacene) and a n-type OSC (N,N’-di-n-octyl-3,4,9,10-perylenetetracarboxylic diimide; PTCDI-C8)in a single green solvent anisole. In particular, shellac was employed as green dielectric materials andthe electrical performance of the resulting devices were compared with those fabricated using toxic solventsor commonly used oxide-based dielectrics. The bulk-heterojunction (BHJ)-structured OTFTs in theoptimized condition exhibited typical ambipolar characteristics with relatively balanced charge carriermobilities as high as 0.042 and 0.14 cm2 V 1s 1 for hole and electron, respectively. Additionally,complementary-like inverters based on the two optimized ambipolar OTFTs showed a decent transfergain as high as 21 at negative supply voltages of 60 V. Thus, by demonstrating the applicability of greensolvents not only for OTFTs but also in the implementation of circuit devices, we expect that the resultsobtained will spark more interest for the more sustainable fabrication of OSC-based electronic devicesand their commercialization/mass-production in the relevant industrial real cases.

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