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      • 콘크리트 덧씌우기 전후 비교조사에 따른 덧씌우기공법의 지지력 및 하중전달 특성 연구

        권순민,서영찬 漢陽大學校 工學技術硏究所 1997 工學技術論文集 Vol.6 No.1

        A 290m 2-lane experimental concrete overlay was constructed in 88 Express Highway to investigate it's feasibility in Korea. The test section consists of both bonded and unbonded type overlays. Pavement condition of the existing slab was surveyed before overlay, and construction feasibility of concrete overlay was checked during construction. After overlay, delamination, crack, deflection(using FWD), and load transfer at various temperature conditions have been measured periodically. Findings from the study can be summarized as follows. (1) The overlays performed successfully during at least 1 year after construction, (2) Overlay reduced deflection by 47% in bonded overlay section and by 57% in unbonded overlay section, (3) Unbonded overlay showed better load transfer than bonded overlay, (4) Joints transfer dowel bar showed better load transfer than those without dowel bar, and (5) Load transfer efficiency varied with temperature conditions.

      • 국가 수준의 과학 지식 평가 체제 개발 : Scientific Knowledge Domain

        최병순,권재술,김찬종 한국교원대학교 과학교육연구소 1998 청람과학교육연구논총 Vol.8 No.1

        과학교육의 정책 수립과 평가 및 과학교육과정의 개편과 효율성 점검 등은 체계적이고 과학적인 연구 결과를 바탕으로 해야 한다. 이를 위해서 주요 선진국에서는 국가 수준 과학 학력평가를 지속적으로 실시하고 발전시켜 왔다. 우리 나라에서 그 동안 실시된 국가 수준 과학 학력평가는 많은 문제점을 가지고 있는 것으로 지적되어 왔으며, 과학 교육 정책 수립 및 평가 그리고 교육과정 개편을 위한 자료 제공에 성공하지 못하였다. 이 연구의 주요 목적은 우리 나라 초·중·고 학생들의 과학 지식 성취의 경향성을 파악하고 향후 주기적으로 진행되어질 국가적 차원의 평가 지표를 만들기 위한 국가 수준의 과학 지식 평가 체제를 개발하는 것이다. 과학교육전문가와 초·중·고 교사들로 연구팀을 구성하고, 교육평가 전문가들과의 협조와 자문을 통해서 국가 수준 과학지식 평가 체제의 방향과 주요 요소를 결정하였다. 또한 문항 개발을 위한 세미나와 워크숍을 통해서 평가문항개발 능력을 향상시켰으며, 계획한 문항을 개발하고, 수정하였으며, 초·중·고교생 958명을 대상으로 예비검사를 실시하고 그 결과를 바탕으로 최종 문항을 380개를 선정하고 수정하였다. 최종 선정한 문항은 다시 초·중·고 학생 8766명을 대상으로 본 검사를 실시하여 문항반응이론(IRT)을 이용하여 문항의 특성을 분석하였다. 연구 결과 국가 수준 과학 지식 평가는 매년 초등학교 5학년, 중학교 2학년, 고등학교 1학년과 2학년을 대상으로 학년말에 실시하는 것이 바람직하다. 표집은 다단계 유층화 표집 방법을 사용하며, 검사지는 복수형으로 개발하며 가교문항을 활용하여 검사지간 학교급간, 종단적 비교의 기초로 삼는다. 본 연구에서는 국가 수준 과학지식 평가 체제를 위하여 각 모집단 별로 문제 은행에 포함시킬 80 내지 100문항씩 총 380문항을 개발하였다. 개발된 문항과 검사의 특성을 분석하여 본 결과 초등학교용 문항들은 중간 또는 중간 이하의 능력을 가진 학생들에게, 중학교용과 고등학교 1학년 용 문항들은 중간 또는 중간 이상의 능력을 가진 학생들에게, 고등학교 자연계용 문항들은 비교적 높은 능력을 가진 학생들에게 적합하였다. 개발한 문항들의 변별도는 우수하거나 매우 우수한 것으로 나타나서, 학생들의 과학 지식 성취를 정확하게 평가하는 데 적합한 것으로 보인다. Establishing and evaluating science education policies and revising and monitoring the effectiveness of science curriculum should be based upon the results of systematic and scientific research studies. Advanced nations have already been administering and developing national level science assessments for these purposes. The science assessments administered in Korea have been reported having many limitations and problems, and not succeeded in providing data for science education policy making and curriculum reform. The major purpose of the study is developing national level science knowledge assessment system in order to identify longitudinal trends of elementary and secondary school students science knowledge achievements. The research team consisted of science education experts and teachers from various school levels, decided the directions and major elements of national level science knowledge assessment with the consultation of educational evaluation experts. Item developing ability of the researchers was improved by seminars and workshops on national assessment in advanced nations and developing skills of writing science items. Nearly 500 items were developed and revised. Pilot test was administered with 958 students at various school levels. 380 items were selected and tested with 8766 students, and the characteristics were analyzed in terms of item response theory. The target populations for national level science knowledge assessment are 5th-grade of elementary school, 2nd-grade of middle school, 1st and 2nd-grade of high school students. The proper period for the assessment is February every year. Multi-stage clustered sampling method is desirable and rotated forms are recommendable for the test format. Bridge items should be introduced to compare the results of multiple tests, and various grades. Anchor items should also be used for longitudinal interpretations of the results. The items for elementary school require low to medium abilities, for middle school and first grade of high school require medium to high abilities and for 2nd-grade of high school high abilities. The discrimination ability of the items developed is high.

      • KCI등재후보

        재해성 요추 추간판 탈출증의 역학 및 임상적 연구 : 비재해성 추간판 탈출증과 비교분석

        권순용,이승구,장일석,김지홍,임영 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

        Objectives : The purpose of study was to define the clinical and epidemiological factors of HNP and to provide the meaningful sources for establishing a prognosis and a rationale for clinical management of occupational low back problem. Methods : This study was performed at eight branch hospitals of Catholic University of Korea and several governmental hospitals for occupational disorders around the Kyunggi province of Korea since Jan. 1985. We analyzed the several factors about lumbar HNP through comparative study of the hospital admission series of each 200 patients in both occupation- and nonoccupation related, subjected to epidemiologic and clinical investigation, respectively. Results : 1. Mean age of occupational HNP was younger (30.9±8.8) than non-occupational HNP (35.2±10.5) (p〈0.05). 2. The duration of clinical symptom before admission was longer in non-occupational HNP(19.9±22.8 Mo.) than in occupational HNP(6.9±12.4 Mo.) (p〈0.05). 3. The symptomatic attack before admission was more frequent in non-occupational HNP(3.7±1.9) than in occupational HNP(2.5±0.9) (p(0.05) 4. There were no significant differences in physical findings between two groups, except for low rate (63%) of straight leg raising test (SLR) limitation in occupational HNP compared to non-occupational HNP(83%) (p〈0.05). 5. Even though The main reason for operative intervention was a failure of conservative treatment in both groups (p〈0.05), extruded subligamentous type was predominant(50%) in occupational HNP (p〈0.05), whereas extruded transligamentous type occupied major portion (67.8%) in non-occupational HNP (p〈0.05). Conclusion : The clinical results were poor in occupational HNP in both conservative and operative management groups, compared to non-occupational HNP (p〈0.05) and mean durations admission and re-admission rate was higher in occupational HNP, compared to non-occupational HNP (p〈0.05).

      • L1210 세포증식에 대한 Glycyrrhizin의 억제작용 기전

        殷載淳,徐龍勳,權鎭,柳東和,吳贊鎬,蘇俊魯,全焄,黃甲洙 우석대학교 의약품개발연구소 1996 藥學硏究誌 Vol.1 No.-

        The purpose of this research was to investigate the mechanism of inhibitory action of Glycyrrhizin(GZ) on the proliferation of mouse leukemia cell-line, L1210 cells. The cytotoxic activity was tested using a colorimetric tertrazolium assay(MTT assay), the apoptosis was tested using flow cytometry. Nitric oxide(NO) production form mouse peritoneal macrophage was tested using a Griess method and the phagocytosis of human polymorphonuclear cells was tested using a lucigenin chemiluminescence. GZ ingibited the proliferation of L1210, BALB/c 3T3 cells and mouse thymocytes at 50 ug/ml/ GZ did not affect nitric oxide production from mouse peritoneal macrophages in vitro, but ingibited nitric oxide production from lipopolysaccharide and y-interferon treated macrophages. Macrophages of GZ-administered mice accelerated NO production. The proliferation of L1210 cells apoptosis of L1210 cells were induced by co-culture with macrophage of GZ-administered mice. The apoptosis of L1210 cells were induced by co-culture with macrophage of GZ-administered mice. GZ increased the phagocytosis of human polymorphonuclear cells. These results suggest that GZ inhibit the proliferation of L1210 cells not only as a direct cytotoxic agent o tumor cells, but also by the enhancement of NO production and phagocytic activity.

      • Cantharis의 세포독성

        殷載淳,權鎭,全焄,吳贊鎬,蘇俊魯 우석대학교 의약품개발연구소 1996 藥學硏究誌 Vol.1 No.-

        The cytotoxicity of cantharidine(CTD), the main component of Cantharis, and the combined effect of CTD and anti-tumor drugs on HeLa. Hep G2,SK-OV3. KOHS-NP, BALB/c 3T3 cells, mouse splenocytes and human lymphocytes were estiated by MTT colorimetry assay. CTD inhibited the proliferation of anti-tumor cells, BALB/C 3T3, mouse spleen cells and human lymphocytes. CTD increased the cytotoxicity of mitomycin C, cisplatin or mercaptopurine on tumor cells and BALB/c 3T3 cells. These results indicate that cantharidine has the cytotoxicity of tumor cells, fibroblast cells and immunocytes.

      • 사군자탕이 L1210 세포를 이식한 마우스의 면역세포에 미치는 영향

        殷載淳,金大根,柳東和,權鎭,徐龍勳,蘇俊魯,全焄,吳贊鎬 우석대학교 의약품개발연구소 1997 藥學硏究誌 Vol.2 No.-

        The purpose of this research was to investigate effects of Sa-Kunja-Tang(SKT) on immune cells of L1210 cell-transplanted mice. The apoptosis and T lymphocytes subopoulation were tested using a flow cytometry, and the proliferation was tested using a MTT assay. Nitric oxide production from mouse peritoneal macrophage was tested using a Griess reagents, and the phagocytic activity of mouse peritoneal macrophage was tested using a lucigenin chemiluminescence. SKT suppressed apoptosis of T-lymphocytes induced by L1210 transplantation. SKT decreased nitric oxide production from mice peritoneal macrophages increased by L1210 transplantation, and the phagocytic activity decreased by L1210 transplantation. These results suggest that SKT suppresses T lymphocyte apoptosis and macrophage activity in L1210 transplanted mice.

      • KCI등재후보

        저주파수 및 저입력전압용 박막형 다중접합 열전변환기

        황찬순,이형주,김진섭,이정희,박세일,권성원 한국센서학회 2002 센서학회지 Vol.11 No.3

        저주파수의 저전압용 크로멜-알루멜 다중접합 열전변환기를 개발하고자 NiCr 히터의 두께를400 nm, 600 nm 및 800 nm로 변화시켰다. 40 Hz∼10 kHz의 직류 역방향 주파수 범위로 0.5 V의 교류 실효전압을 열전변환기에 인가시켰을 때 히터의 두께가 400 nm인 열전변환기가 ±0.51∼±1.69 ppm 범위의 열전효과에 의한 교류-직류 전압 변환오차를 나타내었고, 열전효과 및 주파수에 의한 교류-직류 변환오차는 40 Hz∼l MHz의 주파수 범위에서 ±40∼±115 ppm 범위를 나타내어, 저주파수의 저전압용으로 사용할 수 있었다. NiCr-heaters with three different thicknesses ranging from 400 nm to 800 nm were fabricated and their characteristics were compared for the purpose of developing a chromel-alumel multijunction thermal converter for low input voltage with low frequency. The thermoelectric effect-induced AC-DC voltage transfer difference of the thermal converter with a built-in NiCr-heater of 400 nm-thickness was ±0.51∼±1.69 ppm in the DC reversing frequency of 40 Hz∼10 kHz with appling 0.5 V_rms and the difference was increased to ±40∼±115 ppm in the frequency of 40 Hz~l MHz, when both thermoelectric effects and frequency effects were considered, showing the thermal converter would be suitable for the low input voltage application with low frequency.

      • 사군자탕이 항암제를 투여한 마우스의 면역세포에 미치는 영향

        殷載淳,金大根,柳東和,權鎭,洪鍾星,蘇俊魯,全焄,吳贊鎬 우석대학교 의약품개발연구소 1997 藥學硏究誌 Vol.2 No.-

        The purpose of this research was to investigate effects of Sa-Kunja-Tang(SKT) on immune cells of antitumor drugs administered mice. The apoptosis and T lymphocytes subpopulation were tested using a flow cytometry, and the proliferation was tested using a MTT assay. The administration of etoposide. vincristine or doxorubicin increased the apoptosis of T-lymphocytes, but the action of doxorubicin was decreased by the administration of SKT. The administration of etoposide or vincristine decreased helper T and cytotoxic T cells population of T lymphocytes, but the action of vincristine was recovered by the administration of SCT. The administration of etoposide, vincristine or doxorubicin decreased the proliferation of T-lymphocytes, but the action of doxorubicin was increased by the administration of SKT. These results suggest that SKT has a regulative function of T-lymphocytes in anti-tumor drugs administered mice.

      • KCI등재

        初等敎師의 專門性과 養成大學의 敎科敎育

        장찬익,권순달,최낙준 서울교육대학교 2001 한국초등교육 Vol.13 No.1

        This paper premises that the teacher's performance is different depending on the subject matter in teacher education. The objects of this paper are as follows. At first, this research is reviewed how curriculums of three type teachers education colleges - eleven national universities of education. K national university of education, E womans university - in korea is operating. Secondly, Teacher's performance is interviewed by 26 teachers in 9 elementary schools. They had studied subject matters in each other colleges and universities for elementary teachers. Data is analyzed by triangulations. The results showed that 11 national university of education demands high a grades for student in order to get the certification of teacher. Those of both teachers colleges of university is low. But pre-service subject matter education does not satisfy all of teachers. They assert that curriculums are changed not theory but practical. methods. This study appears that teachers are cultivated the knowledge and teaching method of subject matter in pre-service education.

      • 구름베어링 설계용 Expert System 개발에 관한 연구

        김호룡,권순천 연세대학교 산업기술연구소 1990 논문집 Vol.22 No.2

        In the study, an expert system for the design of rolling bearings has been developed by using GURU which is expert system building tool and by constructing knowledge base which consist of rules and facts. The developed system is composed of three parts : the first one is the bearing selection part that recommands the correct combination of ball and roller bearing to support a shaft for a given set of operationg conditions, as initial stage of bearing design. After requesting the minimum amout of input data from the engineer, the second part calculates the parameters and compares with data-base which constains the specifications of bearing. If the results do not satisfy the selection criterion, the search process is repeated. When the malfunction occurs, the last part displays the causes of bearing failure and the countermeasures for correction. As the result of applying this algorithm to the several real design examples, the proper bearing combination and the bearing dimensions are obtained. Throuth inserting the expertise into the knowledge base, the conceptual design process which could not easily be manipulated by conventional CAD approach could be implemented in computer.

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