생체시료中 Morphine 및 Codeine의 분석

임미애,이종숙,김재균,박세연,성은연,구기서 內務部 國立科學搜査硏究所 1996 國立 科學 搜査 硏究所 年報 Vol.28 No.-

소비자교육이 유아의 소비자지식과 소비자행동에 미치는 영향

제미경,김영옥 대한가정학회 2004 Human Ecology Research(HER) Vol.42 No.2

The purpose of this study is to evaluate a practical consumer education program for kindergarten children and to investigate whether consumer education affects their consumer knowledge and consumer behavior. The subjects of thii study were 32 5-year-old kindergarten children who participated (experimental group) and 25 kindergarten children who did not participate (control group) in the consumer education program. Consumer education was held for 6 hours twice a week during October 8 to 29, 2002. Questionnaire surveys were conducted before and after the education program. Percentiles, frequencies, means, and ANCOVA were uwized for data analysis with SPSS program. The results of this study showed that consumer education had very positive and significant effects on consumer knowledge (pe.01) and consumer behavior (pc.05) among kindergarten children. Furthermore, consumer education for only three weeks had effectively enhanced kindergarten children's ability as consumers. These results imply that consumer education should be served periodically and systematically from an early age. Diverse subjects and teaching methods must be developed and utilized for consumer education of kindergarten children.

장기입원 만성정신질환자의 실태에 관한 조사

김영미,조병만,장기용,정영인 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.4

연구목적 : 부산지역내 정신보건시설에 1년 이상 장기입원하고 있는 만성정신질환자의 실태를 조사하여, 인구사회학적 특성과 장기입원에 영향을 미치는 요인 가운데 직접적인 의료적 요인보다는 주로 간접적인 의료외적인 요인을 알아보고, 이를 바탕으로 향후 만성정신질환자의 효율적 관리를 위한 기초자료를 얻고자 본 연구를 시도하였다. 방 법 연구대상은 1998년 7월1일 현재 부산지역 정신보건시설에서 1년 이상 장기입원중인 3,477명의 만성 정신질환자들이었다. 조사대상기관으로는 10개의 정신병원, 8개의 정신질환자 요양시설이었다. 조사방법은 저자들이 사전에 작성한 자료조사표의 양식을 부산광역시 보건과의 협조를 받아 이들 정신병원과 정신질환자 요양시설에 보내 작성하게 한 다음, 부산광역시의 행정계통을 통해 회수하였다. 자료조사표에는 성별, 연령, 진단명, 정신보건시설의 종류(정신병원, 정신질환자 요양시설), 정신보건법에서 규정한 입원형태(동의입원, 시?? 도지사에 의한 입원, 자의입원). 결혼상태, 교육수준, 요양급여형태, 연고자 유무, 면회횟수 등의 10개의 독립변수가 포함되었다. 자료분석은 입원기간에 따른 대상환자의 분포가 정규분포를 나타내지 않아 독립변수항목들과 입원기간간 의 관련성을 검증하는데는 비모수 방법인 Spear-man 상관계수, Mann-Whitney 검증, Kruskal-Wallis 검증을 사용하였다. 결 과 1) 본 연구의 대상인 1년이상 장기입원중인 환자는 전체입원환자의 70.7%에 해당하였으며 이들 대상 환자의 입원기간의 중앙값은 5.5년이었다. 2) 정신보건시설별 전체환자에 대한 대상환자의 비율은 정신병원과 정신질환자 요양시설이 각각 46.3%, 95.1%로서 정신질환자 요양시설이 정신병원에 비해 장기입원환자의 비율이 높았다. 3) 본 연구에서 설정한 10개 항목의 독립변수 모두에서 입원기간의 유의한 차이를 보여, 이들 변수 모두가 장기입원에 영향을 미치는 것으로 나타났다. 결 론 : 만성정신질환자들의 장기입원에는 상당수의 의료외적인 간접적 요인들도 중요한 역할을 하고 있는 것으로 나타났고, 이는 국내 정신의료서비스의 후진성을 보여주는 것으로 판단되었다. Objectives : In an attempt to identify the demographic characteristics and the factors influencing long-term hospitalization of chronically mentally-ill patients, a survey on the chronically mentally-ill patients who had been staying longer than 1 year in mental health facilities was conducted. Methods : Checklist including some demographic data that were regarded as independent variables was applied to 3,477 subjects through administration system of Pusan Metropolitan City. Statistical analyse were done using distribution-free, non-parametric tests. Results : 1) Subjects who had been staying longer than 1 year were 70.7% of the total inpatients of mental health facilities, and median duration of their hospitalization was 5.5 years. 2) In mental hospitals and asylums, the ratio of chronically mentally-ill subjects to the total inpatients in each facilitiy was 46.3% and 95.1%, respectively. 3) All of the 10 independent variables had an influence on the hospitalization duration. Conclusions : These results indicated that many indirect, extramedical factors had an influence the long-term hospitalization of chronically mentally-ill patients, and it is likely to reflect the underdevelopment of mental health services in Korea.

소비자교육과 관련 변수가 초등학교 학생의 소비자능력에 미치는 영향

제미경,김영옥 한국 가정과 교육 학회 2002 한국가정과교육학회지 Vol.14 No.3

The objectives of this study are to investigate whether consumer education affects the consumer competency and to find out which factors including consumer education affect the consumer competency of elementary school children. The subjects of this study were 43 children at fifth grade to participate in consumer education(experimental group) and 37 children not to participate(control group). Consumer education program was executed for total 20 hours in a semester. Surveys were also conducted twice times to get data for consumer competency and the related factors. The findings are as follows : 1) Consumer education has a positive effect on consumer-role attitude and consumer skill according to the result of ANCOVA. 2) The variables affecting the consumer-role attitude are consumer education and consumer skill of mother in that order according to the result of multiple regression. The variables affecting the consumer skill are consumer skill of mother, consumer education, record of a cashbook and gender in that order. The only variable affecting the consumer knowledge is consumer education.

컴퓨터에 의한 남성복원형의 제도연구

홍정민,최영미 대구효성가톨릭대학교 1991 연구논문집 Vol.43 No.1

The computer system has been used since early 1970's as a computer aided system which produce warious designs in a relatively short time. In especial, the technique is applied to the fields of fashion design and textile design. The purpose of this study is to develop a program in pattern making men's basic pattern by using personal computer. The results are sa folowws; 1. Basic points which can be connected to depict basic pattern are represented woth the numberical expression and the curved lines consisted of three types of arc. 2. A program fo drafting was developed. 3. The pattern was automatically depocted by inputting the standard size and random size. 4. The program includes the function of expressing the specific parts of patterns and of extending the [atterns with or without standard lines.

위장관에 형성된 티로신 결정체 : 부패에 의한 간섭현상

이상용,최영식,임미애 大韓法醫學會 2000 대한법의학회지 Vol.24 No.1

Distinction of antemortem changes from postmortem artifacts is of obvious importance in determining the cause of death. Problems in differential diagnosis may occur as a result of faulty autopsy technique, decomposition changes and destructive environmental factors. Recently we experienced a formation of tyrosine crystals on the gastric and esophageal mucosa of decomposed corpse. The tyrosine crystals found on the gastric and esophageal mucosa were very similar and small pin-head sized whitish gray granules. At first we suspected them as a certain drugs or toxic substances. But the granular materials were confirmed as tyrosine crystals by infrared spectrum analysis. So we report here as a first confirmed case in korea. We think the tyrosine crystal is formed by putrefactive processes and consider as one of the putrefactive artifacts.

6-Exomethylene penamsulfone 유도체의 β-lactamase 저해작용

김해종,여성현,임채욱,임철부,김미영 중앙대학교 약학연구소 1996 약학 논총 Vol.10 No.-

6-Exomethylene penam derivatives were tested as possible β-lactamase inhibitors. The in vitro β-lactamase inhibitory activities were determined by a spectrophotometric assay using Type Ⅰ, Ⅱ, Ⅲ, Ⅳ and TEM β-lactamase. Their activities were compared with sulbactam, tazobactam and clavulanic acid. The 6-exomethylene sulfone derivatives were more potent than clavulanic acid and sulbactam against Type Ⅳ β-lactamase. The Z-isomers showed stronger activities than the E-isomers against TEM and Type Ⅳ β-lactamase.

포스터 전시 발표 순서 : 류마티스 ; 항 면역글로불린 G4 염색 양성을 보이는 Mikulicz 병 1예와 초음파 소견 (초)

Young Wook Kim,Seong Ryul Kwon,Young Chae Chu,Mie Jin Lim,Bo Mook Kim,Won Park 대한내과학회 2009 대한내과학회지 Vol.77 No.4S

Expression and Packaging of a Human Endogenous Retrovirus-K Genomic DNA Clone

Young Mie Ha-Lee 대한미생물학회 2006 Journal of Bacteriology and Virology Vol.36 No.4

Ceramide Induces Apoptosis and Growth Arrest of Human Glioblastoma Cells by Inhibiting Akt Signaling Pathways

( Young Seok Lee ),( Mie Young Kim ),( Young Jin Chun ),( Kwang Sup So ),( Eun Chang Lee ),( Na Hee Park ) 한국응용약물학회 2011 Biomolecules & Therapeutics(구 응용약물학회지) Vol.19 No.1

Ceramide is an important lipid mediator of extracellular signals that control various cellular functions, including apoptosis. In this study, we showed that ceramide induced apoptosis in U373MG human glioblastoma cells associated with G1 cell cycle arrest. Treatment of cells with ceramide increased proapoptotic Bax expression and inhibited the expression of antiapoptotic Bcl-2 and Bcl-xL Ceramide also downregulated cyclin E, cyclin D1, cdk 2, and cdk4 which are involved in regulating cell cycle. In addition, ceramide suppressed phosphorylation of Akt, Bad, p70 S6 kinase, and 4E-BP1, suggesting the involvement of Akt/mTOR signaling pathway. Additionally, okadaic acid, an inhibitor of protein phosphatase 2A, partially blocked the ceramide mediated inhibition of phosphorylation of Akt and 4E-BP1. These results suggest that ceramide induces apoptosis in U373MG glioblastoma cells by regulating multiple signaling pathways that involve cell cycle arrest associated with Akt signaling pathway.