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      • KCI등재

        Innovation and Challenges of Urban Creative Products in Digital Media Art - Tourist cities in China for example

        Ma Xiaoyu,이재우 국제문화기술진흥원 2024 International Journal of Advanced Culture Technolo Vol.12 No.1

        The paper examines the impact of digital media art on urban creative products, analyzing opportunities and challenges in the digital era. It emphasizes the development of urban cultural and creative products, highlighting their significance and future growth potential. The digital media era provides unprecedented innovation opportunities, utilizing advanced tools for efficient design, production, and marketing. Trends like personalization, customization, AI, and big data offer new expressions and market prospects. Cultural products evolve in design, marketing, and sales channels due to digital media, with tools like social media and e-commerce platforms opening new promotion avenues. Case studies illustrate digital media's role in driving innovation and enhancing user experiences. The paper addresses challenges in market competition, copyright, and technological renewal, while recognizing opportunities from AI and big data. The creative industries must adapt and innovate to remain relevant. Looking ahead, urban creative products will evolve under digitalization, relying on digital means to attract consumers and enhance brand value. Cultural products, beyond economic entities, disseminate urban culture and creative spirit. In the digital era, urban creative products demonstrate potential and necessity, prompting a reevaluation of digital technology's role. Through continuous innovation, this field contributes to cultural and economic levels, impacting urban characteristics and heritage. Urban creative products play an increasingly vital role in the global cultural and creative economy.

      • SCOPUSKCI등재
      • KCI등재

        Green Synthesis of Gold Nanoparticles Using Longan Polysaccharide and their Reduction of 4-nitrophenol and Biological Applications

        Xiaoyu Zhang,Liyuan Fan,Yanshuai Cui,Tianming Cui,Shengfu Chen,Guanglong Ma,Wenlong Hou,Longgang Wang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2020 NANO Vol.15 No.02

        The green synthesis of gold nanoparticles (Au NPs) for catalytic and biological applications has been drawing great attention. To compare with plant extracts, the polysaccharides may be good reducing and stabilizing agents. In this work, we describe the preparation of longan polysaccharide stabilized gold nanoparticles (Aun-LP NPs) by reduction of gold ions using a green synthetic method. The formation of gold nanoparticles (Au NPs) was confirmed by UV-Vis spectra. TEM showed that Au NPs had a small size (7.8–15.6 nm) and were highly dispersed without any aggregation. XPS confirmed that the surface elemental composition of Aun-LP NPs was C, O, and Au. DLS demonstrated that Aun-LP NPs had good stability and negative zeta potential. In addition, Aun-LP NPs had high catalytic activity for the reduction of 4-nitrophenol. More importantly, Aun-LP NPs had ignorable cytotoxicity towards HeLa cells and showed good antioxidant activity. Taken together, the results indicated that longan polysaccharide can be used as reducing agents and stabilizers for the preparation of metallic nanoparticles, and the product had wide applications.

      • KCI등재

        Dynamic Event-triggered Control for Heterogeneous Leader-following Consensus of Multi-agent Systems Based on Input-to-state Stability

        Xiaoyu Li,Dazhong Ma,Xuguang Hu,Qiuye Sun 제어·로봇·시스템학회 2020 International Journal of Control, Automation, and Vol.18 No.2

        By utilizing dynamic event-triggered control strategy, this paper deals with consensus problem of a class of heterogeneous leader-following multi-agent systems(MASs) consisting of a high-dimensional leader system but low-dimensional following systems. A kind of observer-based consensus controllers is put forward with a dynamic event-triggered function consisting of the measurement error and a threshold based on the neighbors’ discrete states to reduce unnecessary utilization of limited communication and computation resources. Meanwhile, a dynamic variable is used to generate the event-triggered law using Input-to-State Stability(ISS) criteria. Based on this criteria, the proposed control strategy ensures stability of MASs, which fully reflects of the relationship between the external control inputs of the following systems and the internal states of the leader system and fully considered the influence of disturbances or noises on the MASs. Furthermore, the Zeno behavior for triggering time sequence is excluded. At last, a numerical simulation is provided to demonstrate the feasibility and effectiveness of the theoretical results.

      • KCI등재

        Identification of a Novel CSNK2A1-PDGFRB Fusion Gene in a Patient with Myeloid Neoplasm with Eosinophilia

        Xiaoyu Xu,Qiongyu Lu,Zheng Wang,Ping Cai,Zhao Zeng,Ling Zhang,Man Wang,Liang Ma,Changgeng Ruan,Suning Chen 대한암학회 2021 Cancer Research and Treatment Vol.53 No.3

        Platelet-derived growth factor receptor beta (PDGFRB) rearrangements play an important role in the pathogenesis of eosinophilia-associated myeloid/lymphoid neoplasms. Up to now, more than 70 PDGFRB fusions have been identified. Here, a novel PDGFRB fusion gene CSNK2A1-PDGFRB has been identified in myeloproliferative neoplasm (MPN) with eosinophilia by RNA-sequencing, which has been verified by reverse transcription polymerase chain reaction and Sanger sequencing. The new PDGFRB fusion partner gene CSNK2A1 encoded one of the two catalytic subunit of casein kinase II (CK2). To our knowledge, this is the first report on the involvement of CSNK2A1 in fusion genes, especially fusion with another kinase PDGFRB in MPN. In addition, the CSNK2A1-PDGFRB fusion retained the entire kinase domain of PDGFRB and response to imatinib at low concentration. The patient with CSNK2A1-PDGFRB was sensitive to imatinib treatment and acquired sustained complete remission.

      • KCI등재

        Corticosterone Regulates the Expression of Neuropeptide Y and Reelin in MLO-Y4 Cells

        Yuanyuan Ma,Hang Wang,Xiangnan Wu,Jing Fu,Jiefei Shen,Xiaoyu Li 한국분자세포생물학회 2012 Molecules and cells Vol.33 No.6

        Osteocytes that have a dendritic appearance are widely believed to form a complex cellular network system and play crucial roles in mechanotransduction as a principal bone mechanosensor, which is the basis of their neuronal-like biology, as previously reported. Neuropeptide Y (NPY) and reelin mRNA, which are brain-specific neurogenic markers, have been identified in osteocytes. However, changes in the production of NPY and reelin in response to specific biochemical stimulation are unknown. In this study, we investigated the in vitro effect of corticosterone, one of the endogenous glucocorticoids, on the expression of NPY and reelin in the MLO-Y4 osteocyte cell line. Cells were treated with corticosterone at different concentrations (10-9 M-10-5 M) for 1, 3, 6, 12 and 24 h. As revealed, corticosterone reduced the MLO-Y4 cell viability and pro-liferation in a dose- and time-dependent manner based on an MTT assay and a Vi-CELL analyzer. The cells were then incubated with corticosterone (10-6 M), and the NPY and reelin expression levels were detected at 1, 3, 6, 12 and 24 h using real-time PCR and Western blot analysis. These results demonstrated that at the gene and the protein levels, corticosterone significantly upregulated the NPY and reelin expression in a time-dependent manner. The application of a glucocorticoid receptor antagonist, RU486, reversed the reduced cell viability and the increased expression of NPY and reelin that were caused by corticosterone. To the best of our knowledge, this is the first report to verify that corticosterone regulates the NPY and reelin expression in osteocytes.

      • KCI등재

        Comparative transcriptome analysis to identify genes involved in terpenoid biosynthesis in Agriophyllum squarrosum, a folk medicinal herb native to Asian temperature deserts

        Yin Xiaoyue,Yan-Xia Liu,Qian Chaoju,Zhou Shanshan,Fang Tingzhou,Fan Xingke,Gao yuan,Chang Yuxiao,Yang Jian,Ma Xiao-Fei 한국식물생명공학회 2021 Plant biotechnology reports Vol.15 No.3

        Agriophyllum squarrosum is a folk Mongolian medicine with pleiotropic pharmacological and ecological economic importance endemic to Asian temperature deserts. Terpenoids play critical roles in biotic and abiotic stresses due to their antioxidative activities. Based on non-targeted metabolomic analysis, we detected eight terpenoids enriched in the above-ground tissues of A. squarrosum, however, the molecular mechanism underlying terpenoids biosynthesis in this desert medicinal plant is rarely understood. Here, a comparative transcriptome analysis of diferent tissues in A. squarrosum was conducted to identify 84 unigenes encoding key enzymes in the upstream backbone biosynthesis and 53 unigenes encoding the downstream enzymes for terpenoid diversifcation. Most of the upstream genes exhibited signifcant high expression levels in leaf, and some of which were validated by qRT-PCR. Phylogenetic analysis showed that two downstream gene families OSCs (oxidosqualene cyclases) and TPSs (mainly in terpene synthases -g subfamily) had undergone notable gene expansions in A. squarrosum comparing with the other Amaranthaceae plant species and Arabidopsis. Nevertheless, most members from these two gene families showed the tissue-specifc expression in A. squarrosum, which supported the diversifcation and tissue-specifc enrichment of terpenoids across above-ground tissues. Considering to the habitat characteristics of A. squarrosum, we proposed that the enrichment of terpenoids and the functional diversifcation of terpenoids biosynthesis enzymes were more or less involved into its adaptation to stressful environments of deserts. These results expand the available genetic information underlying terpenoid biosynthesis in A. squarrosum, and contribute to deeper researches on pharmaceutical and eco-agricultural applications in this desert medicinal plant.

      • KCI등재

        Target-biased informed trees: sampling-based method for optimal motion planning in complex environments

        Wang Xianpeng,Ma Xinglu,Li Xiaoxu,Ma Xiaoyu,Li Chunxu 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.2

        Aiming at the problem that the progressively optimized Rapidly-exploring Random Trees Star (RRT*) algorithm generates a large number of redundant nodes, which causes slow convergence and low search efficiency in high-dimensional and complex environments. In this paper we present Target-biased Informed Trees (TBIT*), an improved RRT* path planning algorithm based on target-biased sampling strategy and heuristic optimization strategy. The algorithm adopts a combined target bias strategy in the search phase of finding the initial path to guide the random tree to grow rapidly toward the target direction, thereby reducing the generation of redundant nodes and improving the search efficiency of the algorithm; after the initial path is searched, heuristic sampling is used to optimize the initial path instead of optimizing the random tree, which can benefit from reducing useless calculations, and improve the convergence capability of the algorithm. The experimental results show that the algorithm proposed in this article changes the randomness of the algorithm to a certain extent, and the search efficiency and convergence capability in complex environments have been significantly improved, indicating that the improved algorithm is feasible and efficient.

      • KCI등재

        Effects of biochar and Trichoderma on bacterial community diversity in continuous cropping soil

        Xia Cao,Ning Zhang,Xiaoyu Zeng,Qinglin Lan,Nan Ma,Chuncheng Wu 한국원예학회 2022 Horticulture, Environment, and Biotechnology Vol.63 No.1

        Soil acidifi cation has become a serious issue in protected production in northern China as a consequence of many years ofcontinuous cropping. Besides aff ecting the growth and quality of vegetables, soil acidifi cation also restricts the sustainabledevelopment of vegetables grown in protected environments. A single application of biochar or Trichoderma can repair thesoil environment, optimize the microbial community structure, reduce plant diseases, and promote plant growth. However,it is not known whether biochar combined with Trichoderma has a synergistic eff ect on these parameters. In this study,long-term continuous cropping of cucumbers in a greenhouse was used to study the eff ect of biochar and Trichoderma onmicro-ecological environmental changes in acidifi ed soil using Illumina sequencing. The results showed that the combinedapplication of biochar and Trichoderma promoted cucumber growth; signifi cantly enhanced root vitality and superoxidedismutase, peroxidase, and catalase activities in leaves; and reduced malondialdehyde content. In addition, soil physicaland chemical properties improved; cation exchange capacity, the activity of soil polyphenol oxidase and invertase, and thediversity of soil bacterial communities increased; and the structure and relative abundance of soil bacteria changed after thecombined application of biochar and Trichoderma . Correlation analysis of environmental factors showed that total nitrogenand soil pH had the greatest impact on bacterial communities. The metabolic function of soil bacteria was improved, andthe circulation of soil nutrients was increased as a consequence of the combined application of biochar and Trichoderma .

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