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Facial landmarks detection for evaluating facial paralysis using a modern active shape model
Hung Phuoc Truong,Quan Manh Le,Thinh Long Nguyen,Yong-Guk Kim 한국HCI학회 2018 한국HCI학회 학술대회 Vol.2018 No.1
Facial nerve palsy makes patients lose voluntary muscles movement typically at one side of the human face and then it makes them difficult to interact with people using natural facial expressions. Detection of such symptom and evaluation of how serious it is should be a big challenge for standard face models. We propose a new method by which facial landmarks of the palsy face can be detected and measure the degree of the symptom using Discriminative Bayesian Active Shape Model (DB-ASM). Each patient was asked to make a few facial actions, such as eye closing, E-action and O-action with his mouth. We use facial landmarks detection method in measuring displacement ratios reflecting the structure of regions of eyebrows, eyes and mouth, respectively. There are three steps for this: annotating face model, fitting facial landmarks and measuring symmetry indices on the face. The present dataset contains many videos collected from 14 patients and 6 healthy persons. Experimental result suggests that the model with DB-ASM is useful as a facial landmarks predictor for facial paralysis patients.
Nguyen, Huy Truong,Min, Jung-Eun,Long, Nguyen Phuoc,Thanh, Ma Chi,Le, Thi Hong Van,Lee, Jeongmi,Park, Jeong Hill,Kwon, Sung Won Elsevier 2017 Journal of pharmaceutical and biomedical analysis Vol.142 No.-
<P><B>Abstract</B></P> <P>Agarwood, the resinous heartwood produced by some <I>Aquilaria</I> species such as <I>Aquilaria crassna</I>, <I>Aquilaria malaccensis</I> and <I>Aquilaria sinensis</I>, has been traditionally and widely used in medicine, incenses and especially perfumes. However, up to now, the authentication of agarwood has been largely based on morphological characteristics, a method which is prone to errors and lacks reproducibility. Hence, in this study, we applied metabolomics and a genetic approach to the authentication of two common agarwood chips, those produced by <I>Aquilaria crassna</I> and <I>Aquilaria malaccensis</I>. Primary metabolites, secondary metabolites and DNA markers of agarwood were authenticated by <SUP>1</SUP>H NMR metabolomics, GC–MS metabolomics and DNA-based techniques, respectively. The results indicated that agarwood chips could be classified accurately by all the methods illustrated in this study. Additionally, the pros and cons of each method are also discussed. To the best of our knowledge, our research is the first study detailing all the differences in the primary and secondary metabolites, as well as the DNA markers between the agarwood produced by these two species.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Current examination of agarwood is mostly based on visual examination and thus prone to error. </LI> <LI> Multi-platforms metabolomics well distinguished two popular agarwood types. </LI> <LI> DNA markers also showed clear differences in genetic variation between two agarwood species. </LI> <LI> Metabolomics and genetic approach both well supported the authentication of agarwood. </LI> </UL> </P>
Chien Minh Tran,Ngoc Thi‑Thanh Nguyen,Minh Hieu Ho,Vinh Khanh Doan,Khanh Loan Ly,Nhi Ngoc‑Thao Dang,Nam Minh‑Phuong Tran,Hoai Thi‑Thu Nguyen,Long Phuoc Truong,Thai Minh Do,Quyen Ngoc Tran,Hien Quoc Ng 한국섬유공학회 2023 Fibers and polymers Vol.24 No.1
In this study, we proposed a straightforward electrospun polycaprolactone (PCL) loaded with silver nanoparticles (SNPs)membrane fabrication process, in which SNPs were directly synthesized from silver nitrate (AgNO3) in PCL–acetone mixtureby gamma irradiation. The insolubility of AgNO3in PCL solution was solved using an auxiliary dimethyl sulfoxide solvent. As a physical approach, gamma rays readily converted silver ions into SNPs without the addition of harmful reductionagents, which reduced the cytotoxicity of the synthesized material. By avoiding some processes such as purification, solventremoval, or redispersion of SNPs, this method was more time-saving compared to other related studies. SNPs formation wasconfirmed by both UV–Visible spectrum (UV–Vis) and X-ray diffraction analysis. Scanning electron microscopy (SEM)revealed that the addition of SNPs significantly reduced the fiber diameter of PCL–Ag membranes compared to that of rawPCL. Uniform spherical-shaped SNPs incorporated in PCL fibers were observed under transmission electron microscopy(TEM). The tensile test showed that the electrospun PCL–Ag membranes exhibited good mechanical characteristics. Moistureeasily penetrated the porous microstructure of PCL–Ag, facilitating wound humidity regulation. Inductively coupledplasma-mass spectroscopy (ICP-MS) was employed to study the release profiles of SNPs at different time intervals. Overall,the PCL–Ag 500 ppm sample exerted excellent antibacterial activity against Pseudomonas aeruginosa and Staphylococcusaureus strains and low in vitro cytotoxicity.