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Pushpendra Kumar Dwivedi,R. Vinjamuri,S. K. Sahoo,Krishna Dutta 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.8
Ratcheting deformation in association with bulk texture evolution in HSLA steel is studied in this investigation. The cyclicdeformation behaviors and damage modes of the specimens are obtained at room temperature, employing asymmetric stresscontrolledtests under various combinations of mean stress and stress amplitudes. Bulk texture measurements of the specimensare done adopting an X-ray diffraction analysis. The results exhibit an increase in strain accumulation from 0.23 to 30.61%associated with a sharp reduction in ratcheting life from 3320 to 880 cycles by the increment in mean stress/stress amplitude. A continuous cyclic softening until the final failure is observed for all the ratcheting tests. It is noticed that variation of meanstress is more detrimental than stress amplitude in controlling strain accumulation while the effect of stress amplitude is morepronounced than mean stress for the reduction of ratcheting life. The fracture surface morphology indicates typical striationformation in the crack propagation region along with overload failure. The bulk texture studies indicate that there is a transitionbetween ‘ϒ’ fiber and ‘ζ’ fiber during all loading conditions. The texture intensity is increased from 5.71 to 11.68 withprogressive ratcheting strain accumulation. Here also, influence of stress amplitude is more significant than the mean stress.
Tongue-lip adhesion in Pierre Robin sequence
K. S. Krishna Kumar,Suresh Vylopilli,Anand Sivadasan,Ajit Kumar Pati,Saju Narayanan,Santhy Mohanachandran Nair 대한구강악안면외과학회 2016 대한구강악안면외과학회지 Vol.42 No.1
Patients with Pierre Robin sequence exhibit varying degrees of airway obstruction and feeding difficulty. In some patients, airway obstruction may be profound, warranting surgical intervention to maintain a patent airway. The purpose of this article is to highlight the advantages of the tongue-lip adhesion procedure for the management of airway obstruction in such patients compared to the currently available options.
Synthesis and Antimicrobial Evaluation of Sulfides, Sulfoxides, and Sulfones
Kumar, A.B.V. Kiran,Rao, K.S.V. Krishna,Chandra, M. Subhosh,Subha, M.C.S.,Choi, Yong-Lark The Korean Society for Applied Biological Chemistr 2009 Journal of Applied Biological Chemistry (J. Appl. Vol.52 No.1
Hydrogen peroxide, with sodium metavanadate as the catalyst, was used to achieve a highly efficient and selective oxidation of sulfides into sulfoxides and sulfones at room temperature in high yields and short reaction times. All of the sulfides oxidized into sulfoxides and sulfone derivatives were assayed for their in vitro antibacterial activities against Staphylococcus aureus, Bacillus cereus, Escherichia coli, and Pseudomonas aeruginosa, and antifungal activities against Aspergillus niger and Candida albicans. A remarkable inhibition of the growth of the bacterial and fungal strains was observed. This result suggested that the compounds are promising microbial agents.
Synthesis and Antimicrobial Evaluation of Sulfides, Sulfoxides, and Sulfones
A.B.V. Kiran Kumar,K.S.V. Krishna Rao,M. Subhosh Chandra,M.C.S. Subha,Yong Lark Choi 한국응용생명화학회 2009 Journal of Applied Biological Chemistry (J. Appl. Vol.52 No.1
Hydrogen peroxide, with sodium metavanadate as the catalyst, was used to achieve a highly efficient and selective oxidation of sulfides into sulfoxides and sulfones at room temperature in high yields and short reaction times. All of the sulfides oxidized into sulfoxides and sulfone derivatives were assayed for their in vitro antibacterial activities against Staphylococcus aureus, Bacillus cereus, Escherichia coli, and Pseudomonas aeruginosa, and antifungal activities against Aspergillus niger and Candida albicans. A remarkable inhibition of the growth of the bacterial and fungal strains was observed. This result suggested that the compounds are promising microbial agents. Hydrogen peroxide, with sodium metavanadate as the catalyst, was used to achieve a highly efficient and selective oxidation of sulfides into sulfoxides and sulfones at room temperature in high yields and short reaction times. All of the sulfides oxidized into sulfoxides and sulfone derivatives were assayed for their in vitro antibacterial activities against Staphylococcus aureus, Bacillus cereus, Escherichia coli, and Pseudomonas aeruginosa, and antifungal activities against Aspergillus niger and Candida albicans. A remarkable inhibition of the growth of the bacterial and fungal strains was observed. This result suggested that the compounds are promising microbial agents.
H. Joy Hoskeri,V. Krishna,B. Vinay Kumar,A. H. Shridar,K. Ramesh Babu,M. S. Sudarshana 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.10
The prophylactic effects of oleanolic acid (OA) isolated from chloroform extract (CE) of Flaveria trinervia against ethanol induced liver toxicity was investigated using rats. CE and OA at three different doses were tested by administering orally to the ethanol treated animals during the last week of the 7 weeks study. Silymarin was used as the standard reference. The substantially elevated serum enzymatic levels of serum glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, alkaline phosphatase and bilirubin in ethanol treated animals were restored towards normalcy by treatment of CE and OA. In vivo antioxidant and in vitro free radical scavenging activities were also positive for all the three concentrations of CE and OA. However, OA at 150 mg/kg showed significant activity when compared to the other two doses. Biochemical observations in support with histopathological examinations revealed that CE and OA possess hepatoprotective action against ethanol induced hepatotoxicity in rats.
( Kamal ),( Ahmed ),( Anver Basha Shaik ),( C. Ganesh Kumar ),( Poornima Mongolla ),( P. Usha Rani ),( K. V. S ),( Rama Krishna ),( Suman Kumar Mamidyala ),( Joveeta Joseph ) 한국미생물 · 생명공학회 2012 Journal of microbiology and biotechnology Vol.22 No.1
In an ongoing survey of the bioactive potential of microorganisms from Ladakh, India, the culture medium of a bacterial strain of a new Pseudomonas sp., strain ICTB-745, isolated from an alkaline soil sample collected from Leh, Ladakh, India, was found to contain metabolites that exhibited broad-spectrum antimicrobial and biosurfactant activities. Bioactivity-guided purification resulted in the isolation of four bioactive compounds. Their chemical structures were elucidated by 1H and 13C NMR, 2D-NMR (HMBC, HSQC, 1H,1H-COSY, and DEPT- 135), FT-IR, and mass spectroscopic methods, and were identified as 1-hydroxyphenazine, phenazine-1-carboxylic acid (PCA), rhamnolipid-1 (RL-1), and rhamnolipid-2 (RL-2). These metabolites exhibited various biological activities like antimicrobial and efficient cytotoxic potencies against different human tumor cell lines such as HeLa, HepG2, A549, and MDA MB 231. RL-1 and RL-2 exhibited a dose-dependent antifeedant activity against Spodoptera litura, producing about 82.06% and 73.66% antifeedant activity, whereas PCA showed a moderate antifeedant activity (63.67%) at 60 μg/cm2 area of castor leaf. Furthermore, PCA, RL-1, and RL-2 exhibited about 65%, 52%, and 47% mortality, respectively, against Rhyzopertha dominica at 20 μg/ml. This is the first report of rhamnolipids as antifeedant metabolites against Spodoptera litura and as insecticidal metabolites against Rhyzopertha dominica. The metabolites from Pseudomonas sp. strain ICTB-745 have interesting potential for use as a biopesticide in pest control programs.