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P247 : A study on use of complementary and alternative medicine for acne
( Sook Kyung Lee ),( Taek Geun Lee ),( Hyun Hwang Bo ),( Tae Gwang Kwon ),( Se Won Jung ),( Young Seok Lee ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: Complementary and alternative medicine (CAM) is any practice that has healing effects, but is not based on evidence demonstrated by scientific method. Recently, CAM has been used in various diseases including acne. However, there have been no studies on CAM for acne in Korea. Objectives: The purpose of this study was to analyze the use of CAM in acne patients. Methods: A total of 159 patients with acne were enrolled on the study, and filled out a questionnaire about use of CAM. Results: Overall 87.4% (139/159) of the patients reported the previous or current use of at least one more type of CAM. Cosmetics for acne (100, 22.9%) was most frequently used, followed by diet therapy (81, 18.5%), spa and bath therapies (77, 17.6%), health food supplement (67, 15.3%), skin care shop (64, 14.6%), oriental medicine (38, 8.7%), and aromatherapy (9, 2.1%). The most common reason for using CAM was ``wish to try everything`` (28.6%), and the most common source of information was internet (40.5%). The therapeutic effect of CAM was best with diet therapy (32.1%). The most common side effect of CAM was aggravation of symptoms. The most common monthly cost for CAM was between 50,000 and 100,000 won/person. Conclusion: As our results, we can predict that the use of various types of CAM for acne will become more common. Therefore, dermatologists need to study about benefits and adverse effects of CAM for acne.
장아름,전수형,박세정,이현미,김규곤,이용태,지규용,이인선,김종원,Jang, A-Reum,Jeon, Soo-Hyung,Park, Se-Jung,Lee, Hyun-Mi,Kim, Kyu-Kon,Lee, Yong-Tae,Ji, Gyu-Yong,Lee, In-Sun,Kim, Jong-Won 사상체질의학회 2010 사상체질의학회지 Vol.22 No.3
1. Objectives: This study was performed to research the relationship between Sasang Constitutional medicine and Hyungsang medicine. 2. Methods: Four hundred and thirty applicants are involved in this study. They are devided into Sasang Constitution and Hyungsang Classification 3. Results and Conclusions: There are significances between Sasang Constitutional diagnosis and Hyungsang Classification. There are significantly more Bangkwang-body, Gi-kwa, Taeyang-hyung, Yangmyung-hyung in Taeyangin and Bangkwang-body, Jung-kwa, Soyang-hyung, Yangmyung-hyung in Soyangin. There are significantly more Dam-body, Gi-kwa, Taeyang-hyung, Yangmyung-hyung in Taeeumin and Bangkwang-body, Gi-kwa, Taeyang-hyung, Yangmyung-hyung in Soeumin.
Se-Ra Lee,Jung-Min Yon,Mi-Ra Kim,Yan Jin,In-Jeoung Baek,Yun-Bae Kim,Byeongwoo Ahn,Beom-Jun Lee,Young Won Yun,Sang-Yoon Nam 한국실험동물학회 2007 Laboratory Animal Research Vol.23 No.1
Licorice, the root of the leguminous Glycyrrhiza, is one of the most frequently employed botanicals in foods and traditional medicines, which is composed of triterpene saponins, flavonoids, polysaccharides, pectins, simple sugars, amino acids, mineral salts, and various other substances. To investigate whether licorice affects on the antioxidant system of male reproductive organs, we analyzed the mRNA expression pattern of glutathione peroxidase (GPx) family (type 1-4) in the reproductive tissues including testes, epididymides, prostates, and seminal vesicles of rats exposed to licorice. Licorice extracts (0, 0.5, 1, and 2 g/㎏ body weight) were treated to 6-week-old-male rats for 4 weeks daily per oral. Total RNAs were extracted from the male reproductive tissues, and then RT-PCR was performed with the specific primers of each GPx enzyme. The GPx1 mRNA expression was similar to control group in testes, epididymides, and seminal vesicles, but was significantly increased in the prostates exposed to 0.5, 1, and 2 g/㎏ of licorice. There was no significant difference in the expression of GPx2 mRNA among control group and licorice-treated groups. The GPx3 mRNA was weakly increased except for 2 g/㎏ group in testes, but was weakly decreased in epididymides. GPx4 mRNA was not changed in testes, but was slightly decreased in epididymides, seminal vesicles, and prostates by 0.5 and 2 g/㎏ of licorice. These findings indicate that licorice affects the expression of GPx genes in male reproductive system.
Proportion of Non-Medical Opioid Use of Prescription Opioids among Cancer Patients in Korea
Se-Il Go,Jung Hye Kwon,Sung Woo Park,Gyeong-Won Lee,Jung Hun Kang,Eduardo Bruera 한국호스피스완화의료학회 2023 한국호스피스.완화의료학회지 Vol.26 No.4
Purpose: Limited research has been conducted on the prevalence of non-medical opioid use (NMOU) in Korean cancer patients who have received prescription opioids (PO). This study aimed to identify the potential proportion of NMOU in cancer patients who had been prescribed opioids in Korea. Methods: A retrospective cohort analysis was conducted on 14,728 patients who underwent cancer-related treatment between January 2009 and December 2019, using electronically collected data from a tertiary hospital in Korea. Information regarding the type and duration of opioid use was gathered. A detailed review of medical charts was carried out, focusing on patients who had been prescribed opioids for over 60 days beyond a 12-month period following the completion of their cancer treatment (long-term PO users). Results: Out of the 5,587 patients who were prescribed PO and followed up for at least 12 months, 13 cases of NMOU were identified, representing 0.23% of the patient population. Among the 204 long-term PO users, the rate was 6.37% (13/204). The most commonly misused opioids were oxycodone and fentanyl. For the group confirmed to have NMOU, the median duration of prescription was 1,327 days in total. Of the 13 patients diagnosed with NMOU, 9 reported withdrawal symptoms, 3 exhibited craving behavior for opioids, and 1 experienced both symptoms. Conclusion: This study found that 0.23% of cancer patients who had been prescribed opioids in Korea demonstrated NMOU. Despite this relatively low rate, careful monitoring is necessary to minimize the risk of NMOU in this population, especially among long-term PO users.
Se-Ra Lee,Jung-Min Yon,Mi-Ra Kim,Yan-Jin,In-Jeoung Baek,Yun-Bae Kim,Byeongwoo Ahn,Beom-Jun Lee,Sang-Yoon Nam,Young Won Yun 한국실험동물학회 2007 Laboratory Animal Research Vol.23 No.1
To understand the antioxidative effect of licorice on the female reproductive system, we analyzed the mRNA expression patterns of glutathione peroxidase (GPx) family (type 1-4) in the ovary and uterus of rats exposed to licorice. Licorice, the root of the leguminous Glycyrrhiza, is one of the most frequently employed botanicals in foods and traditional medicines, which is known to have antioxidant, anti-tumor, anti-allergic and antiviral activities, in addition to estrogenic properties. However, there is no report on the effects of licorice in the reproductive organs. Licorice extracts (0, 0.5, 1, and 2 g/㎏ body weight) were treated to 8-week-old female rats for 4 weeks daily per oral. Total RNAs were extracted from ovary and uterus and then RT-PCR analysis was performed with the specific primers of each GPx enzyme. In ovaries, GPx1, GPx3, and GPx4 mRNA levels were slightly decreased compared with those of control group. Especially, GPx3 mRNA expression was decreased dose-dependantly in ovaries. However, GPx2 mRNA was weakly increased in ovary. On the contrary, the gene expression of GPx1-3 in uteri tended to increase slightly compared to control group. GPx4 mRNA expression was decreased by 0.5 g/㎏ of licorice in uterus, but increased by treatment with 1 and 2 g/㎏ of licorice. These findings indicate that licorice maybe differently influenced on the antioxidant systems of ovary and uterus.