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권영만,황원중,권성민,조준형,이명구,김남훈 江原大學校 森林科學硏究所 2005 Journal of Forest Science Vol.21 No.-
국내에서 재배한 kenaf의 해부학적 특성을 광학현미경법으로 조사하였다. Kenaf의 수피부에는 인피섬유, 사부방사조직, 피층유세포 등이 존해하였고, 목질부는 도관, 목섬유, 방사조직 등으로 구성되어 있었다. 도관은 고립관공과 2~3개가 방사방향으로 복합한 복합관공이 많이 존재하였고, 방사조직은 평복, 직립, 방형세포가 모두 분포하고 있었다. 접선단면에서 방사조직은 단열 및 다열방사조직으로 구성되었다. 수피비의 인피섬유층은 생장기간과 함께 증가하였다. Anatomical properties of Kenaf cultivated in Korea was investigated using light microscopy. Bast fiber, phloem ray and cortex parencyma cell were observed in bast, and vessel, wood fiber and rat in core. A lot of solitary and multiple radial pores in core existed. The cell type of ray parenchyma in radial section was procumbent, upright and square sell. Uniseriate and multiseriate rays existed in tangential section. The layer of bast fiber in bast increased with in creasing the growth period.
마우스의 BCG감염이 R.tsutsugamushi의 증식에 미치는 영향
김인재,전창덕,홍영권,정현택,이복수,장우현,김익상,박석돈 대한감염학회 1993 감염 Vol.25 No.2
It has recently been reported that gamma-inteferon(INF-r) and tumor necrosis factor(TNF) or lipopplysaccharide(LPS) activate macrophages to kill intracellular parasites by means of nitrc oxide (NO). It is now generally accepted that NO is the endothelium-derived relaxing factor, and that it also paticipates in the regulation of the nervous and immune systems. Activated macrophages form NO?? and NO?? from the terminal guanidino nitrogen atoms of L-arginine by the process now known to proceed via the formation of NO. This pathway is inhibited by the L-arginine analog(N?? monomethyl-L-arginine; N??MMA), forms L-citrulline as a co-product and is responsible for the cytotoxic action of macrophages. In this study, the authors found that INF-r and/or LPS induced murine macrophages to kill Rickettsiae tsutsugamushi in vitro and macrophages from BCG-infected mice got the host resistance against R.tsutsugamushi in vitro as well as in vivo. The rickettsicidal effect induced by the combination of INF-r and/or LPS induced mice got the host resistance against R.tsutsugamushi in vitro as well as in vivo. The rickettsicidal effect induced by the combination of INF-r and/or LPS can also be completely inhibited by N??MMA, leading to a dose-dependent inhibition of NO production. These datademonstrate that INF-r and/or LPS as well as BCG-activated macrophages mediate host resistance aganist R.tsutsugamushi infection through NO, which is necessary for the intracellular parasite.
金八圭,鄭海駿,權五憲,姜準默,林熙大 충남대학교 공업교육연구소 1981 論文集 Vol.4 No.1
Korea enters a new era of industrial modernization, spurred by her successive five-year economic development plans. The labor-intensive light industry that led the nation's economy in the past decades is undergoing a gradual shift to the technology-intensive heavy and chemical industry. The demand for industry-minded young technician is thereby ever mounting in number in various industrial sectors, which in turn creates many challenging issues on Civil Engineering Education. Among them, this paper deals exclusively with the curriculum of the Department of Civil Engineering Education. As the results of a trade analysis for graduates from technical high schools, it was realized that current curriculum were somewhat isolated from outside environment and found too rigid to meet the changing requirements. Needless to mention, teachers play a vital roles in the technician education. Accordingly the teacher must be qualified well not only in knowledge on the major subjects but also in practices. The improvement of current curriculum is strongly recommended to produce qualified teachers, taking into account the changing social demands. This study is very limited in terms of finance, time allowance and manpower. Accordingly the model curriculum was based on the trade analysis, social requirements and the current curriculum, and its justification was not verified by tests and broad reviews.
( Ji Yong Kim ),( Jai Sung Lee ),( Yong Seok Han ),( Jun Hee Lee ),( Inhyu Bae ),( Yeo Min Yoon ),( Sang Mo Kwon ),( Sang Hun Lee ) 한국응용약물학회 2015 Biomolecules & Therapeutics(구 응용약물학회지) Vol.23 No.6
Human mesenchymal stem cells (MSCs) have been used in cell-based therapy to promote revascularization after peripheral or myocardial ischemia. High levels of reactive oxygen species (ROS) are involved in the senescence and apoptosis of MSCs, causing defective neovascularization. Here, we examined the effect of the natural antioxidant lycopene on oxidative stress-induced apoptosis in MSCs. Although H2O2 (200 mM) increased intracellular ROS levels in human MSCs, lycopene (10 μmM) pretreatment suppressed H2O2-induced ROS generation and increased survival. H2O2-induced ROS increased the levels of phosphorylated p38 mitogen activated protein kinase (MAPK), Jun-N-terminal kinase (JNK), ataxia telangiectasia mutated (ATM), and p53, which were inhibited by lycopene pretreatment. Furthermore, lycopene pretreatment decreased the expression of cleaved poly (ADP ribose) polymerase-1 (PARP-1) and caspase-3 and increased the expression of B-cell lymphoma 2 (Bcl-2) and Bcl-2-associated X protein (Bax), which were induced by H2O2 treatment. Moreover, lycopene significantly increased manganese superoxide dismutase (MnSOD) expression and decreased cellular ROS levels via the PI3K-Akt pathway. Our findings show that lycopene pretreatment prevents ischemic injury by suppressing apoptosis-associated signal pathway and enhancing anti-oxidant protein, suggesting that lycopene could be developed as a beneficial broad-spectrum agent for the successful MSC transplantation in ischemic diseases.
Kim, Ji Yong,Lee, Jai-Sung,Han, Yong-Seok,Lee, Jun Hee,Bae, Inhyu,Yoon, Yeo Min,Kwon, Sang Mo,Lee, Sang Hun The Korean Society of Applied Pharmacology 2015 Biomolecules & Therapeutics(구 응용약물학회지) Vol.23 No.6
Human mesenchymal stem cells (MSCs) have been used in cell-based therapy to promote revascularization after peripheral or myocardial ischemia. High levels of reactive oxygen species (ROS) are involved in the senescence and apoptosis of MSCs, causing defective neovascularization. Here, we examined the effect of the natural antioxidant lycopene on oxidative stress-induced apoptosis in MSCs. Although $H_2O_2$ ($200{\mu}M$) increased intracellular ROS levels in human MSCs, lycopene ($10{\mu}M$) pretreatment suppressed $H_2O_2$-induced ROS generation and increased survival. $H_2O_2$-induced ROS increased the levels of phosphorylated p38 mitogen activated protein kinase (MAPK), Jun-N-terminal kinase (JNK), ataxia telangiectasia mutated (ATM), and p53, which were inhibited by lycopene pretreatment. Furthermore, lycopene pretreatment decreased the expression of cleaved poly (ADP ribose) polymerase-1 (PARP-1) and caspase-3 and increased the expression of B-cell lymphoma 2 (Bcl-2) and Bcl-2-associated X protein (Bax), which were induced by $H_2O_2$ treatment. Moreover, lycopene significantly increased manganese superoxide dismutase (MnSOD) expression and decreased cellular ROS levels via the PI3K-Akt pathway. Our findings show that lycopene pretreatment prevents ischemic injury by suppressing apoptosis-associated signal pathway and enhancing anti-oxidant protein, suggesting that lycopene could be developed as a beneficial broad-spectrum agent for the successful MSC transplantation in ischemic diseases.
Detection of Pulmonary Region in Medical Images through Improved Active Control Model
Kwon Yong-Jun,Won Chul-Ho,Kim Dong-Hun,Kim Pil-Un,Park Il-Yong,Park Hee-Jun,Lee Jyung-Hyun,Kim Myoung-Nam,Cho Jin-HO The Korean Society of Medical and Biological Engin 2005 의공학회지 Vol.26 No.6
Active contour models have been extensively used to segment, match, and track objects of interest in computer vision and image processing applications, particularly to locate object boundaries. With conventional methods an object boundary can be extracted by controlling the internal energy and external energy based on energy minimization. However, this still leaves a number of problems, such as initialization and poor convergence in concave regions. In particular, a contour is unable to enter a concave region based on the stretching and bending characteristic of the internal energy. Therefore, this study proposes a method that controls the internal energy by moving the local perpendicular bisector point of each control point on the contour, and determines the object boundary by minimizing the energy relative to the external energy. Convergence at a concave region can then be effectively implemented as regards the feature of interest using the internal energy, plus several objects can be detected using a multi-detection method based on the initial contour. The proposed method is compared with other conventional methods through objective validation and subjective consideration. As a result, it is anticipated that the proposed method can be efficiently applied to the detection of the pulmonary parenchyma region in medical images.
Kwon, Soo-Hun,Joo, Hyo-Jun,Kwon, Hyuck-In Elsevier 2018 Ceramics international Vol.44 No.17
<P><B>Abstract</B></P> <P>In this study, simultaneous ultraviolet and thermal (SUT) treatment is proposed as an effective post-deposition treatment technique to lower the annealing temperature required for the formation of p-type SnO thin-films. The chemical, electrical, and optical properties of the radio-frequency (RF)-sputtered SnO<SUB>X</SUB> thin-films subjected to the conventional thermal and SUT treatments at different temperatures (as-deposited, 125 °C, 150 °C, 175 °C, and 200 °C) were investigated using X-ray diffraction, X-ray photoelectron spectroscopy, scanning electron microscopy, Hall measurements, and ultraviolet-visible-near infrared spectroscopy. The experimental results revealed that the p-type SnO was the dominant phase of the SnO<SUB>X</SUB> thin-film after SUT treatment at 150 °C, which is considerably lower than the annealing temperature of 200 °C required for the formation of the p-type SnO thin-film using the conventional thermal annealing process. The observed phenomenon can be attributed to the reactive oxygen radicals produced by ultraviolet irradiation during the SUT treatment. The proposed post-deposition SUT treatment technique in this work may be useful in various applications that require the formation of p-type SnO thin-films using a low-temperature process.</P>