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韓國女眞語文學的豊碩成果 : 金東昭敎授《女眞語滿語硏究》讀後
김계종 효성여자대학교 한국전통문화연구소 1995 韓國傳統文化硏究 Vol.10 No.-
我從遼寧回到京的第二年, 使我高興論一件事, 是韓國女眞語文學家星女子大學金東昭敎授的光臨舍下, 記得當時是承延邊大學崔羲秀敎授同來介紹的. 初談之際, 卽感到金東昭敎授對女眞文硏究的深度·廣度, 令人佩服. 兩年之後, 使我更高興的事美得到了金東昭敎授的文集≪女眞語滿語硏究≫, 這本書是中央民族大學黃有福敎授譯成的中文本. 本來我曾與金東昭敎授互贈著作. 但承他寄贈的≪韓國語與通古斯語音韻比較硏究≫(1981), ≪同文類解滿州文語語彙≫(1982), 皆 金東昭敎授授執敎的曉星女子大學出版部所出, 印製精良. 彌足診貴. 而奉面又以≪女眞譯語≫等書影爲地, 更覺親切, 其眞對女眞語文硏究之重視, 亦由此可見. 我本早想寫-篇介紹, 但因限于朝鮮語文程度, 遲遲不果. 今得此中譯本能洞悉著作眞諦, 理當爲之游揚.
프레탈^(R)정(실로스타졸 50mg)에 대한 실로졸^(R)정의 생물학적 동등성
최한곤,권기철,이승호,김학미,박병주,유봉규,이종달,이경희,하정희,우종수,박인숙,최진석,용철순 한국병원약사회 2003 병원약사회지 Vol.20 No.1
Bioequivalence of two cilostazol tablets, the Pletaal^(R)(Korea Otsuka Pharmaceutical Co., Ltd.) and the Cilozol^(R)(Hanmi Pharmaceutical Co., Ltd.), was evaluated according to the guideline of KFDA, Sixteen normal male volunteers(age 20~29 years old) were divided into two groups and a randomized 22 cross-over study was employed. After two tablets containing 50㎎ of cilostazol were orally administered. blood was taken at predetermined time intervals and the concentration of cilostazol in plasma was determined with an HPLC method using UV detector. The pharmacokinetic parameters(C_(max), T_(max) and AUC_(t)) were calculated and ANOVA was utilized for the statistical analysis of parameters. The results showed that the differences in C_(max), T_(max) and AUC_(t) between two tablets were 4.99%, 1.74% and 7.68%, respectively. The powers(1-β) for C_(max), T_(max) and AUC_(t) were83.92%, 80.12% and 85.03%, respectively. Detectable differences(Δ) and confidence intervals were all less than 20%, and confidence interval of all the parameters were also less than 20% at the significance level(α) of 0.05. All of these parameters met the criteria of KFDA for bioequivalence, indicating that Cilozol^(R) tablet is bioequivalent to Pletaal^(R) tablet.
Epidemiological Characteristics of Norovirus Outbreaks in Shenyang from 2017 to 2021
Qi Ying,Dong Xinxin,Cheng Xiaowei,Xu Han,Wang Jin,Wang Bing,Chen Ye,Sun Baijun,Zhang Linlin,Yao Yan 한국미생물학회 2023 The journal of microbiology Vol.61 No.4
Norovirus is one of the leading causes of acute gastroenteritis outbreaks worldwide. This study aimed to identify the epidemiological characteristics of norovirus outbreaks and to provide evidence for public health entities. Specimens and epidemiological survey data were collected to determine if there were differences in the attack rate of norovirus in terms of the year, season, transmission route, exposure setting, and region and to determine whether there were relationships between the reporting interval, the number of illnesses in a single outbreak and the duration of the outbreak. Norovirus outbreaks were reported throughout the year, with seasonal characteristics (i.e., high rates in spring and winter). Among all regions in Shenyang with the exception of Huanggu and Liaozhong, norovirus outbreaks had been reported, and the primary genotype was GII.2[P16]. Vomiting was the most common symptom. The main places of occurrence were childcare institutions and schools. The person-to-person route was the main transmission route. The median duration of norovirus was 3 days (IQR [interquartile range]: 2–6 days), the median reporting interval was 2 days (IQR: 1–4 days), the median number of illnesses in a single outbreak was 16 (IQR: 10–25); there was a positive correlation between these parameters. Norovirus surveillance and genotyping studies still need to be further strengthened to increase knowledge regarding the pathogens and their variant characteristics, to better characterize the patterns of norovirus outbreaks and to provide information for outbreak prevention. Norovirus outbreaks should be detected, reported and handled early. Public health entities and the government should develop corresponding measures for different seasons, transmission routes, exposure settings, and regions.
Effect of humidity on mechanical properties of dissolving microneedles for transdermal drug delivery
Qi Lei Wang,Jia Wei Ren,Bo Zhi Chen,Xuan Jin,Can Yang Zhang,Xin Dong Guo 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.59 No.-
Dissolving microneedles (DMNs) prepared from soluble polymers has been being widely investigated as a safe and effective transdermal delivery system for drug and vaccine. Limited by the materials, the air humidity would probably affect the mechanical property of DMNs, which is essential for the effective needle insertions and drug delivery. In this study, four kinds DMNs prepared by polyvinyl alcohol, sodium hyaluronate (HA), chitosan and gelatin are studied on the mechanical strength and insertion ability under varying humidity conditions. Based on these investigations, we hope to provide the effective time of DMNs to ensure a successful insertion and drug delivery.
Jin Cai,Xu‑Sheng Wu,Pan Sun,Jun Sun,Qi‑jun Deng 전력전자학회 2021 JOURNAL OF POWER ELECTRONICS Vol.21 No.12
The mutual inductance parameters change from time to time. When conducting dynamic wireless power transfer using an inductive power transfer system, it results in larger fluctuation of output power. Therefore, a parameter optimization method is necessary to improve the stability of inductive power transfer system during dynamic misalignment. In this study, a nonlinear programing model with objective function of minimum voltage gain difference was established by taking S-LCC topology as an example. Genetic algorithm and nonlinear programming were combined to optimize the compensating parameters of the system and to realize minimum fluctuation of output voltage gain of the system within any given range of mutual inductance parameters. Optimization results show that output stability can be realized by adjusting the compensation capacitance in the primary side. The feasibility of the theory was verified through stimulation and test prototype. Test results show that when the mutual induction range is from 29.3 μH to 84.3 μH, the voltage gain of the system varies from 0.67 to 0.77. The fluctuation ratio of voltage gain is 6.7%, and the fluctuation ratio of voltage gain under the circumstance of resonance parameters is 40.2%.
Qi‑Lei Dai,Kun Li,Kai‑Ren Meng,Zhou Fang,Wen Chen,Tian‑Bao Yang,Chi Feng,Jin‑Ming Wu,R. D. K. Misra 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.4
Advanced automotive industries generate large demand for the next generation of high strength and high toughness springsteels. Vanadium-containing 55SiCrV spring steels subjected to rapid-induction heating treatment can fulfil such requirements. However, the effect of vanadium microalloying under online rapid-induction heat treatments is rarely reported. Acomparative study of the microstructure and tensile properties of 55SiCr and 55SiCrV spring steel wires subjected to a novelonline rapid induction heat treatment has been demonstrated herein. It is found that the tensile strength of the 55SiCr springwire decreases with the decrease in the wire speed in online rapid-induction heating, and the plasticity increases. Whereas,the tensile strength of the 55SiCrV steel wire increases with the decrease in the wire speed with the retained high plasticity,which is attributed to the strengthening effect of the dislocations. Through the optimized rapid-induction heating/coolingthermal cycles and intermediate-temperature tempering treatment, the tensile strength of the 55SiCrV steel wire approaches2106 MPa with total elongation of 9.7%. Compared with the 55SiCr spring steel, the addition of V in 55SiCrV spring steelchanges the strengthening and toughening mechanisms via the grain refinement and enhancement in the hardenability andtempering resistance. The finely dispersed V-containing secondary phases are rarely found in the matrix, which indicates thatthe precipitation effect stemming from the addition of V is not the dominant strengthening factor in the online rapid-inductionheat process. The proposed novel online rapid-induction heat treatment provides a promising pathway for the mechanicalproperty improvement of the spring steel.
New Glycosides from Dracocephalum tanguticum Maxim
Qi Zeng,Hui-zi Jin,Ruijie Chang,Jiangjiang Qin,Xiangrong Cheng,Weidong Zhang 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.12
Four new glycosides, luteolin-7-methoxy-3'-O-(3''-O-acetyl)-β-D-gluco pyranuronic acid-6''-methyl ester (1), benzyl-6-[(2E)-2-butenoate]-β-D-glucopyranoside (2), 2-methoxy-4-(2-propen-1-yl)penyl-6-acetate-β-D-glucopyranoside (3), and 2-methoxy-4-(2-propen-1-yl)penyl-6-[(2E)-2-butenoate]-β- D-glucopyranoside (4), along with benzyl-β-D-glucopyranoside (5), 2-methoxy-4-(2-propen-1-yl)penyl-β-D-glucopyranoside (6), and pectolarigenin (7), were isolated from the whole plant of Dracocephalum tanguticum Maxim. The structures of 1-4 were elucidated by detailed spectroscopic analyses, including HR-ESI-MS and 2D NMR spectroscopic data. The inhibitory effects against nitric oxide production in LPS-stimulated RAW264.7 cells of all seven compounds were also evaluated.