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New Glycosides from Dracocephalum tanguticum Maxim
Qi Zeng,Hui-zi Jin,Ruijie Chang,Jiangjiang Qin,Xiangrong Cheng,Weidong Zhang 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.12
Four new glycosides, luteolin-7-methoxy-3'-O-(3''-O-acetyl)-β-D-gluco pyranuronic acid-6''-methyl ester (1), benzyl-6-[(2E)-2-butenoate]-β-D-glucopyranoside (2), 2-methoxy-4-(2-propen-1-yl)penyl-6-acetate-β-D-glucopyranoside (3), and 2-methoxy-4-(2-propen-1-yl)penyl-6-[(2E)-2-butenoate]-β- D-glucopyranoside (4), along with benzyl-β-D-glucopyranoside (5), 2-methoxy-4-(2-propen-1-yl)penyl-β-D-glucopyranoside (6), and pectolarigenin (7), were isolated from the whole plant of Dracocephalum tanguticum Maxim. The structures of 1-4 were elucidated by detailed spectroscopic analyses, including HR-ESI-MS and 2D NMR spectroscopic data. The inhibitory effects against nitric oxide production in LPS-stimulated RAW264.7 cells of all seven compounds were also evaluated.