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      • Metaheuristic-reinforced neural network for predicting the compressive strength of concrete

        Pan Hu,Zohre Moradi,H. Elhosiny Ali,Loke Kok Foong 국제구조공학회 2022 Smart Structures and Systems, An International Jou Vol.30 No.2

        Computational drawbacks associated with regular predictive models have motivated engineers to use hybrid techniques in dealing with complex engineering tasks like simulating the compressive strength of concrete (CSC). This study evaluates the efficiency of tree potential metaheuristic schemes, namely shuffled complex evolution (SCE), multi-verse optimizer (MVO), and beetle antennae search (BAS) for optimizing the performance of a multi-layer perceptron (MLP) system. The models are fed by the information of 1030 concrete specimens (where the amount of cement, blast furnace slag (BFS), fly ash (FA1), water, superplasticizer (SP), coarse aggregate (CA), and fine aggregate (FA2) are taken as independent factors). The results of the ensembles are compared to unreinforced MLP to examine improvements resulted from the incorporation of the SCE, MVO, and BAS. It was shown that these algorithms can considerably enhance the training and prediction accuracy of the MLP. Overall, the proposed models are capable of presenting an early, inexpensive, and reliable prediction of the CSC. Due to the higher accuracy of the BAS-based model, a predictive formula is extracted from this algorithm.

      • KCI등재

        Advanced Small-Signal Model of Multi-Terminal Modular Multilevel Converters for Power Systems Based on Dynamic Phasors

        Pan Hu,Hongkun Chen,Lei Chen,Xiaohang Zhu,Xuechun Wang 전력전자학회 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.2

        Modular multilevel converter (MMC)-based high-voltage direct current (HVDC) presents attractive technical advantages and contributes to enhanced system operation and reduced oscillation damping in dynamic MMC–HVDC systems. We propose an advanced small-signal multi-terminal MMC–HVDC based on dynamic phasors and state space for power system stability analysis to enhance computational accuracy and reduce simulation time. In accordance with active and passive network control strategies for multi-terminal MMC–HVDC, the matchable small-signal stability models containing high harmonics and dynamics of internal variables are conducted, and a related theoretical derivation is carried out. The proposed advanced small-signal model is then compared with electromagnetic–transient and traditional small-signal state-space models by adopting a typical multi-terminal MMC–HVDC network with offshore wind generation. Simulation indicates that the advanced small-signal model can successfully follow the electromechanical transient response with small errors and can predict the damped oscillations. The validity and applicability of the proposed model are effectively confirmed.

      • SCISCIESCOPUS

        Octazethrene and Its Isomer with Different Diradical Characters and Chemical Reactivity: The Role of the Bridge Structure

        Hu, Pan,Lee, Sangsu,Park, Kyu Hyung,Das, Soumyajit,Herng, Tun Seng,Gonç,alves, Thé,o P.,Huang, Kuo-Wei,Ding, Jun,Kim, Dongho,Wu, Jishan American Chemical Society 2016 Journal of organic chemistry Vol.81 No.7

        <P>The fundamental relationship between structure and diradical character is important for the development of open-shell diradicaloid-based materials. In this work, we synthesized two structural isomers bearing a 2,6-naphthoquinodimethane or a 1,5-naphthoquinodimethane bridge and demonstrated that their diradical characters and chemical reactivity are quite different. The mesityl-or pentafluorophenyl-substituted octazethrene derivatives <B>OZ-M/OZ-F</B> and their isomer <B>OZI-M</B> (with mesityl substituents) were synthesized via an intramolecular Friedel–Crafts alkylation followed by oxidative dehydrogenation strategy from the key building blocks <B>4</B> and <B>11</B>. Our detailed experimental and theoretical studies showed that both isomers have an open-shell singlet ground state with a remarkable diradical character (<I>y</I><SUB>0</SUB> = 0.35 and 0.34 for <B>OZ-M</B> and <B>OZ-F</B>, and <I>y</I><SUB>0</SUB> = 0.58 for <B>OZI-M</B>). Compounds <B>OZ-M</B> and <B>OZ-F</B> have good stability in an ambient environment, while <B>OZI-M</B> has high reactivity and can be easily oxidized to a dioxo product <B>15</B>, which can be correlated to their different diradical characters. Additionally, we investigated the physical properties of <B>OZ-M</B>, <B>OZ-F</B>, and <B>15</B>.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/joceah/2016/joceah.2016.81.issue-7/acs.joc.6b00172/production/images/medium/jo-2016-00172x_0011.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/jo6b00172'>ACS Electronic Supporting Info</A></P>

      • The Study of Chinese Public Service Announcements Using the Concept of Metaphor

        Hu Pan(호반),Jinho Lee(이진호) 한국콘텐츠학회 2009 한국콘텐츠학회 종합학술대회 논문집 Vol.7 No.1

        Metaphors, as an important way to deliver information and convince the audience, have been used in print advertising extensively. This study researches the concept of metaphors and analyses seven Chinese advertisements in which metaphors are used in public service advertising. The nature of metaphors is to express one thing by using another thing. Using metaphors can put some creative ideas into pictures and make the pictures full of visual impact. Then the target audience will pay more attention to the picture and become impressed. When people look at the advertisements using metaphors, they will definitely look up in their existing knowledge to understand the message which the advertisements are delivering. So this makes the advertisements more attractive and the people would be more easily convinced.

      • SCIESCOPUSKCI등재

        Advanced Small-Signal Model of Multi-Terminal Modular Multilevel Converters for Power Systems Based on Dynamic Phasors

        Hu, Pan,Chen, Hongkun,Chen, Lei,Zhu, Xiaohang,Wang, Xuechun The Korean Institute of Power Electronics 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.2

        Modular multilevel converter (MMC)-based high-voltage direct current (HVDC) presents attractive technical advantages and contributes to enhanced system operation and reduced oscillation damping in dynamic MMC-HVDC systems. We propose an advanced small-signal multi-terminal MMC-HVDC based on dynamic phasors and state space for power system stability analysis to enhance computational accuracy and reduce simulation time. In accordance with active and passive network control strategies for multi-terminal MMC-HVDC, the matchable small-signal stability models containing high harmonics and dynamics of internal variables are conducted, and a related theoretical derivation is carried out. The proposed advanced small-signal model is then compared with electromagnetic-transient and traditional small-signal state-space models by adopting a typical multi-terminal MMC-HVDC network with offshore wind generation. Simulation indicates that the advanced small-signal model can successfully follow the electromechanical transient response with small errors and can predict the damped oscillations. The validity and applicability of the proposed model are effectively confirmed.

      • Association of TNF-α-308 and -238 Polymorphisms with Risk of Cervical Cancer: A Meta-analysis

        Pan, Feng,Tian, Jing,Ji, Chu-Shu,He, Yi-Fu,Han, Xing-Hua,Wang, Yong,Du, Jian-Ping,Jiang, Feng-Shou,Zhang, Ying,Pan, Yue-Yin,Hu, Bing Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11

        Published data on the associations between tumor necrosis factor-alpha (TNF-${\alpha}$) promoter -308G>A and -238G>A polymorphisms and cervical cancer risk are inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. Data were collected from MEDLINE and PubMed databases. Crude odds ratios (ORs) with 95% confidence intervals (CIs) were calculated in a fixed/random effect model. 13 separate studies including 3294 cases and 3468 controls were involved in the meta-analysis. We found no association between TNF-${\alpha}$-308G>A polymorphism and cervical cancer in overall population. In subgroup analysis, significantly elevated risks were found in Caucasian population (A vs. G: OR = 1.43, 95% CI = 1.00-2.03; AA vs. GG: OR = 2.09, 95% CI = 1.34-3.25; Recessive model: OR = 2.09, 95% CI = 1.35-3.25) and African population (GA vs. GG: OR = 1.53, 95% CI = 1.02-2.30). An association of TNF-${\alpha}$-238G>A polymorphism with cervical cancer was found (A vs. G: OR = 0.61, 95% CI = 0.47-0.78; GA vs. GG: OR = 0.59, 95% CI = 0.45-0.77; Dominant model: OR = 0.59, 95% CI = 0.46-0.77). When stratified by ethnicity, similar association was observed in Caucasian population (A vs. G: OR = 0.62, 95% CI = 0.46-0.84; GA vs. GG: OR = 0.59, 95% CI = 0.43-0.82; Dominant model: OR = 0.60, 95% CI = 0.44-0.83). In summary, this meta-analysis suggests that TNF-${\alpha}$-238A allele significantly decreased the cervical cancer risk, and the TNF-${\alpha}$-308G>A polymorphism is associated with the susceptibility to cervical cancer in Caucasian and African population.

      • Toward Tetraradicaloid: The Effect of Fusion Mode on Radical Character and Chemical Reactivity

        Hu, Pan,Lee, Sangsu,Herng, Tun Seng,Aratani, Naoki,Gonç,alves, Thé,o P.,Qi, Qingbiao,Shi, Xueliang,Yamada, Hiroko,Huang, Kuo-Wei,Ding, Jun,Kim, Dongho,Wu, Jishan American Chemical Society 2016 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.138 No.3

        <P>Open-shell singlet diradicaloids display unique electronic, nonlinear optical, and magnetic activity and could become novel molecular materials for organic electronics, photonics, and spintronics. However, design and synthesis of diradicaloids with a significant polyradical character is a challenging task for chemists. In this Article, we report our efforts toward a tetraradicaloid system. A series of potential tetraradicaloids by fusion of two p-quinodimethane (p-QDM) units with naphthalene or benzene rings in different modes were synthesized. Their model compounds containing one p-QDM moiety were also prepared and compared. Their ground-state structures, physical properties, and chemical reactivity were systematically investigated by various experimental methods such as steady-state and transient absorption, two-photon absorption, X-ray crystallographic analysis, electron spin resonance, superconducting quantum interference device, and electrochemistry, assisted by density functional theory calculations. It was found that their diradical and tetraradical characters show a clear dependence on the fusion mode. Upon the introduction of more five-membered rings, the diradical characters greatly decrease. This difference can be explained by the pro-aromaticity/antiaromaticity of the molecules as well as the intramolecular charge transfer. Our comprehensive studies provide a guideline for the design and synthesis of stable open-shell singlet polycyclic hydrocarbons with significant polyradical characters.</P>

      • KCI등재

        Resveratrol enhances the functionality and improves the regeneration of mesenchymal stem cell aggregates

        Yi-Jing Wang,Pan Zhao,Bing-Dong Sui,Nu Liu,Cheng-Hu Hu,Ji Chen,Chen-Xi Zheng,An-Qi Liu,Kun Xuan,Ya-Ping Pan,Yan Jin 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-

        Mesenchymal stem cell (MSC)-based regeneration, specifically cell aggregate or cell sheet engineering, is a promising approach for tissue reconstruction. Considering the advantages of ease of harvest and lack of immune rejection, the application of autologous MSCs (i.e., patients’ own MSCs) in regenerative medicine has developed considerable interest. However, the impaired cell viability and regenerative potential following MSCs impacted by disease remain a major challenge. Resveratrol (RSV) exhibits reliable and extensive rejuvenative activities that have received increasing clinical attention. Here, we uncovered that resveratrol enhances the functionality and improves the regeneration of mesenchymal stem cell aggregates. Periodontal ligament MSCs (PDLSCs) from normal control subjects (N-PDLSCs) and periodontitis patients (P-PDLSCs) were investigated. Compared to N-PDLSCs, P-PDLSCs were less capable of forming cell aggregates, and P-PDLSC aggregates showed impaired osteogenesis and regeneration. These functional declines could be mimicked in N-PDLSCs by tumor necrosis factor alpha (TNF-α) treatment. Notably, a TNF-α-induced functional decline in N-PDLSC aggregates was rescued by RSV application. More importantly, in both N-PDLSCs and P-PDLSCs, RSV promoted cell aggregate formation and improved their osteogenic potential. Furthermore, as proven ectopically in vivo, the tissue regenerative capability of P-PDLSC aggregates was also enhanced after RSV treatment during aggregate formation in vitro. Finally, in a rat in situ regeneration model, we successfully applied both N-PDLSC aggregates and P-PDLSC aggregates to repair periodontal defects upon long-term functional improvements by RSV preconditioning. Together, our data unravel a novel methodology for using pharmacology (i.e., RSV)-based cell aggregate engineering to improve the functionality and facilitate the regeneration of MSCs from both healthy and inflammatory microenvironments, shedding light on improving the application of autologous MSC-mediated regenerative medicine.

      • KCI등재

        Nano La2O3 as a heterogeneous catalyst for biodiesel synthesis by transesterification of Jatropha curcas L. oil

        Quan Zhou,Song Yang,Heng Zhang,Fei Chang,Hu Li,Hu Pan,Wei Xue,De-Yu Hu 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.31 No.-

        A comparative study on the activity of La2O3 and two kinds of nano La2O3 catalysts prepared usingsonochemical (nano La2O3-S) and hydrothermal methods in the transesterification to produce biodieselwas conducted. The relatively high activity of nano La2O3 catalysts may be ascribed to their high basestrength, large base amount, small particle size and large BET surface areas. Nano La2O3-S was selectedfor further optimisation due to its simple preparation procedure and short preparation time. The FAMEcontent and yield obtained were successively 97.6% and 90.3% under optimal conditions. Moreover, nanoLa2O3-S showed a remarkable tolerance to FFA.

      • KCI등재

        Population dynamics of Frankliniella occidentalis Pergrande and its predator Orius similis Zheng on common crops and surrounding plants

        Hu Changxiong,Li Yiru,Chen Guohua,Duan Pan,Wu Daohui,Liu Qing,Yin Honghui,Xu Tianyang,Zhang Xiaoming 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.3

        Frankliniella occidentalis Pergrande is important invasive pests in China, causing damage to agricultural pro duction, and Orius similis Zheng is the dominant predator species of F. occidentalis. A two-year survey was conducted to determine the population density of F. occidentalis and O. similis, on chili (Capsicum annuum L.) and maize (Zea mays L.) crops and surrounding weed species, which included white clover (Trifolium repens L.), St. John’s wort (Hypericum beanii N. Robson), alfalfa (Medicago sativa L.) and beggarticks (Bidens pilosa L.) in Kunming, southern China. The activity of F. occidentalis on these 6 host plant species was determined using the quartile method. F. occidentalis mainly damaged plants during their flowering stage. The main activity period of F. occidentalis occurred earlier on H. beanii and T. repens than on C. annuum. The peak activity of F. occidentalis occurred in the middle of May (on T. repens). During the whole activity period, the highest thrips densities were recorded on H. beanii among all of the sampled host plant species, followed by C. annuum. The lowest density was recorded on B. pilosa. Dynamics of immature F. occidentalis were more irregular than that of adults. The highest density of O. similis was recorded on Z. mays. It was 2.27–26.43-fold (2017) and 2.01–19.09-fold (2018) higher than that on other host plant species. This study showed that F. occidentalis could migrate between C. annuum and surrounding weeds. The weeds were the main source of thrips on C. annuum. The results indicated that Z. mays can be planted around C. annuum fields as a potential banker plant, to attract O. similis to control F. occidentalis on C. annuum, T. repens and B. pilosa. The flowering period of plants and surrounding plant species has a great effect to the population activities of F. occidentalis and predator O. similis on crops.

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