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Thiol의 친핵성 첨가물의 합성(제Ⅸ보) (Diacylivinylaryloxy)acetic acid 유도체와 그 Thioglycolic Acid 참가생성물의 합성
한인섭,김태린,허태성,최재희 聖心女子大學校 1989 論文集 Vol.21 No.-
이뇨작용 및 항종양효과가 있으리라고 예상되는 (acetylbenzoylvinyloxy)acetic acid 유도체(3a-3d)와 (dibenzoylvinylaryloxy)acetic acid 유도체 (3e-3h) 및 이들의 thioglycolic acid 첨가생성물(4a-4h)을 합성하였다. (dibenzoylvinylaryloxy)acetic acid 유도체는 hydroxybenzaldehyde 유도체로부터 monochloroacetic acid를 이용하여 2단계 반응으로 합성하였다. (Acetylbenzoylvinyloxy)acetic acid derivatives(3a-3d), (dibenzoylvinylaryloxy) acetic acid dervatives(3e-3h) and their thioglycolic acid adducts(4a-4h) which are expected to have diurectic activities and antitumour effect were synthesized. (Diacylvinylaryloxy)acetic acid derivatives wer prepared from hydoxybenzaldehyde derivatives via two step reaction employing monochloraccetic acid.
Surveillance of Coronavirus Disease 2019 (COVID-19) Testing in Clinical Laboratories in Korea
Huh Hee Jae,Hong Ki Ho,Kim Taek Soo,Song Sang Hoon,Roh Kyoung Ho,Lee Hyukmin,Kwon Gye Cheol 대한진단검사의학회 2021 Annals of Laboratory Medicine Vol.41 No.2
In response to the ongoing coronavirus disease 2019 (COVID-19) pandemic, an online laboratory surveillance system was established to monitor severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) real-time reverse transcription-PCR (rRT-PCR) testing capacities and results. SARS-CoV-2 rRT-PCR testing data were collected from 97 clinical laboratories, including 84 medical institutions and 13 independent clinical laboratories in Korea. We assessed the testing capacities to utilize SARS-CoV-2 rRT-PCR based on surveillance data obtained from February 7th to June 4th, 2020 and evaluated positive result characteristics according to the reagents used and sample types. A total of 1,890,319 SARS-CoV-2 rRT-PCR testing were performed, 2.3% of which were positive. Strong correlations were observed between the envelope (E) gene and RNA-dependent RNA polymerase (RdRp)/nucleocapsid (N) genes threshold cycle (Ct) values for each reagent. No statistically significant differences in gene Ct values were observed between the paired upper and lower respiratory tract samples, except in the N gene for nasopharyngeal swab and sputum samples. Our study showed that clinical laboratories in Korea have rapidly expanded their testing capacities in response to the COVID-19 outbreak, with a peak daily capacity of 34,193 tests. Rapid expansion in testing capacity is a critical component of the national response to the ongoing pandemic
경관적 재구성을 통한 “장성 필암서원” 경관짜임의 독해(讀解)
노재현 ( Jae Hyun Rho ),허준 ( Joon Huh ),최종희 ( Jong Hee Choi ) 한국전통조경학회 2014 한국전통조경학회지 Vol.32 No.2
본 연구는 장성 필암서원의 입지·형국·풍수지리 등 장소성에 담긴 의미경관적 요소와 서원배치에 따른 시지각적 공간구성에 담긴 미학성 독해를 위해 시도되었다. 고지도에 표기된 ``필암서원``, ``필봉서원``, ``김하서서원`` 등에서 보이듯 ``필암``은 곧 ``필봉``이며 이는 ``김하서``라는 인식이 드러나고 있다. 서원의 배산 필암산(문필산)과 필암(붓바위)은 필암서원 장소정체성 구축의 핵심이며 하서 김인후의 상징으로, 연고성을 바탕으로 한 깊은 인걸지령(人傑地靈)의 관계로 엮여있음이 읽혀진다. 필암서원은 안산(案山) 없이 파노라믹한 ``증산들``을 안대(案對)로 한 계거(溪居)의 입지특성을 보인다. 하서의 태생지인 맥동마을과 필암 그리고 ``단봉함서형(丹鳳含書形)`` 형국을 반영한 서원의 터잡기와 조형적 반영 그리고 건물 ``이름붙이기``에서 드러난 필암서원의 액호(額號)와 각 건물의 당호(堂號) 또한 성리학적 가르침을 바탕으로, 자연과 인간이 하나 되는 천인합일(天人合一)의 인식 결과에 따른 기호경관적 특질은 여타 서원 보다 뚜렷하다. 확연루(누문)-청절당(강당)-진덕재·숭의재(재실)-우동사(사당)의「전당후재형」배치로 구축된 교접마당을 통한 중심성의 극대화는 필암서원 고유의 공간 프레임적 특성이다. 여기에 더하여 ``유식공간과 제향공간내 경장각과 계생비 배치로 얻어진 내심 이동``을 통한 중심성의 강화`` 그리고 ``영역성의 강화를 위한 시설과 장치`` 등에서 필암서원의 공간구성상의 경관짜임이 읽혀진다. 또한 ``창호 구성을 통한 조망 중심성의 강화``, ``「틀에넣기」와 중첩을 통한 시각적 투명성 확보`` 그리고 ``재실 툇마루 높이를 통한 위계성의 구현`` 등의 시각구성상의 경관짜임을 통해 성리학적 사고를 바탕으로 한 질서와 미학성이 필암서원 조형에 논리적으로 구현되었음을 독해하였다. 이와 같이 경관 재구성을 통해 정리되고 새롭게 읽혀진 필암서원의 의미체계와 공간 및 시각구성상의 미학성은 결코 우연이 아닌 필연적 결과로, 장성 필암서원의 내적 충일을 높일 수 있는 요인이며 또 다른 자원기반이다. 본 연구를 통해 얻은 경관독해의 결과가 필암서원에 대한 이해 증진과 드러나지 않은 문화경관에 대한 감수성을 높이는데 기여할 것을 기대한다. This study was conducted to identify landscaping elements such as location, situation and feng shui included in the spatiality of Jangseong Pilmaseowon and to interpret aesthetic features of visual-perceptual spatial composition according to its arrangement. As it is shown in ’Pilamseowon’, ’Pilbongseowon’, and ’Gimhaseoseowon’ appearing in antique maps, the awareness considering ’Pilam’ as ’Pilbong’ and ’Gimhaseo’ was revealed. Mountain Pilamsan[Mountain Munpilsan] which is the location of seowon and Pilam(Brush-shaped rock) is the core of establishment of location identity of Pilamseowon and the symbol of Haseo Kim In-hu, which shows that they are deeply related to Ingeoljiryeong(人傑地靈: ‘a place derives reflected glory from an illustrious human’) based on connection. Pilamseowon shows locational characteristics of living in stream(溪居) facing panoramic ‘jeungsan field’ without Ansan(案山). Based on the teachings of Neo-Confucianism, Village Maekdong which is the birth place of Haseo, Pilam, seowon geomancy considering the Danbonghamseo-type(丹鳳含書形) geographical shape, formative reflection, Pilmaseowon and structures revealed in building naming more clearly show symbolic landscaping features resulting from ’theory of ’Heaven-Man Unity’(天人合一)’ representing the union of nature and haman, than other seowons. The maximization of centrality through connected yards constructed with the ’jeondang hujae(前堂後齋)’ arrangement in the order of Whakyeon-lu, Chenogjeol-dang, Jindeak-jae or Sungui-jae, and Woodong-sa is a unique feature of spatial frame of Pilmaseowon. In addition, it reveals the centrality reinforced with ’the move of inner center through arrangement of Kyeongjang-kag and Kyesengbi inside ‘YuSik(遊息)’ space and religious space’ and the landscaping arrangement of Pilmaseowon from installation and device for reinforcement of territoriality. Moreover, it was found that orders and aesthetic features based on Neo-Confucianism were logically realized in the formation of Pilmaseowon with visual and compositional landscaping arrangement such as ’reinforcement of view centrality through composition of windows and doors’, ’securement of visual transparency through framing and duplication’, and ‘realization of hierarchy through height of jaesil toenmaru’. The meaning system and spatial or visual aesthetic features of Pilmaseowon newly arranged and interpreted through landscaping recomposition is not a coincidental but inevitable result. It is another resource basis and an element that can improve the internal exuberance of Pilamseowon. This landscaping reading study is expected to improve the understanding of landscapes of Pilmaseowon and elevate the sensibility of unrevealed cultural landscapes.
개선된 De-loading기법을 이용한 해상풍력 연계용 HVDC의 DC 전압의 제어방안
허재선(Jae-Sun Huh),문원식(Won-Sik Moon),박상인(Sang-In Park),김두희(Doo-Hee Kim),김재철(Jae-Chul Kim) 대한전기학회 2015 전기학회논문지 Vol.64 No.3
This paper presents the DC voltage control method in DC link of High Voltage Direct Current(HVDC) for an offshore wind farm in Low Voltage Ride Through(LVRT) situation. Wind generators in an offshore wind farm are connected to onshore network via HVDC transmission. Due to LVRT control of grid side inverter in HVDC, power imbalancing in DC link is generated and this consequentially causes rising of DC voltage. A de-loading scheme is one of the method to protect the wind power system DC link capacitors from over voltage. But the flaw of this method is slow control response time and that it needs long recovery time to pre-fault condition after fault clear. Thus, this paper proposes improved de-loading method and we analyze control performance for DC voltage in LVRT control of HVDC for an offshore wind farm.