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강원도 화천군 수달(Lutra lutra) 서식지의 식생 구조
서형수 ( Hyung Soo Seo ),신영섭 ( Young Seob Shin ),이경은 ( Kyung Eun Lee ),김윤미 ( Yoon Mi Kim ),전미나 ( Mina Jeon ),남택우 ( Taek Woo Nam ),한성용 ( Sung Yong Han ),정연숙 ( Yeonsook Choung ) 한국하천호수학회 2014 생태와 환경 Vol.47 No.special
In order to determine whether vegetation would be one of the factors for the selection of otter home range, vegetation structure and other potential factors were studied in Hwacheon, Korea. Thirteen sites, otter’s activity found and not found, were investigated in North Han River and connected tributary streams of Hwacheon-gun. Three types of vegetation were classified by cluster analysis, which is short grass, tall grass and shrub type. Vegetation zone of each channel is composed of either one type, or mosaic of tall grass and shrub type. Short grass type is common in Lake Paro and upper North Han-river where water level is highly variable throughout a year. Therefore, annual species such as Persicaria nodosa, Fimbristylis dichotomam and Chenopodium ficifolium are the most dominant. Shrub type is common at the downstream sites of Jichon stream and along mainstream of North Han River down Lake Paro. A shrub species, Salix koreensis, is the most common. Tall grass type is dominant occupying the most vegetation zone of the tributary channels. Phragmites japonica is absolutely dominant. Due to its dense cover, a few plant species are co-existed. Otter activity was found in all three vegetation types and no marked activity was found at some sites of tall grass type. There is no difference in species composition and physiognomy between tall grass sites with and without otter activity, while it shows significant difference in fish availability between two groups. Overall we found that home range of otters in the region is along the mainstream and downstream of tributary streams with high fish availability in all vegetation types and in various human activity levels.
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혈압점(血壓點)에 윤제(潤劑)의 주입이 고혈압에 미치는 영향
위종성,한재섭,박희수,박재영,Owi, Jong-Sung,Han, Jai-Seop,Park, Hee-Soo,Park, Jai-Young 대한약침학회 2002 Journal of pharmacopuncture Vol.5 No.1
Objective: This study was designed to evaluate the possibility of Hypertension by moistening Herbal-acupuncture at Blood Pressure Point(HN136). Methods: We reviewed 14 patients of Hypertension. They were hospitalized at oriental medical hospital of Sang-Ji university for 2002. 1. 2. - 2002. 5. 2. First, we divided into two groups; Group Ⅰ was administrated by moistening Herbal-acupuncture at Blood Pressure Point(HN136), and was not given any western medicine about Hypertension during the period of experiment. Group Ⅱ was administrated by moistening Herbal-acupuncture at Blood Pressure Point(HN136), and given western medicine about Hypertension during the period of experiment. we observed the change of systolic and diastolic for 2 weeks, and compared Group Ⅰ with Group Ⅱ . Results: The results obtained as follows: 1. The figure of systolic in Group Ⅰ was decreased, but there was no signification. There was a significant decrease in Group Ⅱ (p<0.05) 2. The figure of diastolic in Group Ⅰ was decreased, but there was no signification. There was a significant decrease in Group Ⅱ (p<0.05) 3. Group Ⅱ was more effective than Group Ⅰ in the results. Conclusion: The results suggest that moistening Herbal-acupuncture at Blood Pressure Point(HN136) was effective treatment of Hypertension. So further research is needed continuously.
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최도영,이재동,백용현,이송실,유명철,한정수,양형인,박상도,유미현,박은경,박동석,Choi, Do-young,Lee, Jae-dong,Back, Yong-hyeon,Lee, Song-shil,Yoo, Myung-chul,Han, Chung-soo,Yang, Hyung-in,Park, Sang-do,Ryu, Mi-hyun,Park, Eun-kyung,Park, 대한침구의학회 2004 대한침구의학회지 Vol.21 No.4
Objective : Rheumatoid arthritis is an autoimmune disease that pathogenesis is not fully understood and one of the most intractable musculoskeletal diseases. The concern in the immunopathogenesis of rheumatoid arthritis has been increased since 1980's and many immunotherapeutic agents including disease-modifying antirheumatic drugs (DMARDs) were developed and became the mainstay of treatment of rheumatoid arthritis. However, the cure of the disease has hardly been achieved. In oriental medicine, rheumatoid arthritis is related to Bi-Zheng(痺證), that presents pain, swelling, andlor loss of joint function as major clinical manifestations, and also known to be deeply involved in suppression of immune function related to weakness of Jung-Ki(正氣). The herbal medicine, empirically used, could be a potential resource of development of new immunotherapeutic agents for rheumatoid arthritis. Methods : We developed a search strategy using terms to include "rheumatoid arthritis and herbal medicine" combined with "Chinese medicine" and/or "Oriental medicine". The search was focused on experimental studies of herbal medicine (January 1999 to May 2004), which is known to have effects on immune function of patients with rheumatoid arthritis. Computerized search used Internet databases including KISS and RISS4U (Korea), CNKI (China), MOMJ (Main Oriental Medicine Journal, Japan), and PubMed. The articles were selected from journals of universities or major research institutes. Results : The literature search for experimental studies on effects of herbal medicine on immunity of rheumatoid arthritis retrieved a total of 21 articles (Korea; 8, China ; 12, Japan ; 1). Of 21 articles, 10 were related to single-drug formula, 2 to drug interaction, and 9 to multi-drug formula. Single-drug formula was mainly used for aqua-acupuncture and researches on active components. Studies of drug interaction emphasized harmony of Ki-Hyul(氣血) and balance of Han-Yeul(寒熱). Multi-drug regimen was mainly found among formulas for Bo-Ki-Hyul(補氣血) and Bo-Sin(補腎). Conclusion : Studies on rheumatoid arthritis were performed both in vitro and in vivo in vitro study, LPS-stimulated splenocytes and synoviocytes were treated with herbal medicine, resulting in proliferation and activation of immune cells and suppression of cytokine activities in vivo study CIA animal model demonstrated that herbal medicine decreased antibody production and improved function of immune cells. In cellular and molecular study herbal medicine showed profound effects on the level of mRNA expression of certain cytokines related to immune function. This study revealed that herbal medicine has significant immune modulatory action and could be used for recovery of immune dysfunction of rheumatoid arthritis patients.
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Environmental Management in Industry
Han, Sang Wook,Kim, Ik Soo,Terence P. CURRAN 한국환경정책학회 1995 環境政策 Vol.3 No.1
환경문제를 야기시키는 원인은 인간 그 자체에 있으며, 경제주체별로는 개인, 기업, 정부로 볼 수 있다. 시시각각 변화하고 강화되여가는 국제환경질서에 대처하기 위해서는 기업과 정부가 협조적인 관계를 유지하면서 각각의 역할을 하여야하는 바, 기업은 사회공헌책임주의에 입각하여 환경친화책인 기업경영을 도입, 실천해야 하며, 정부는 이를 지원, 촉진하기 위한 정책을 펼쳐야 할 것이다. 이 논문은 지구차원에서의 환경문제, 미국과 한국의 최근 환경정책 그리고 기업에서의 환경경영도입의 중요성과 환경경영이 모든 조직기능에서 통합 고려되어야 하는 필요성올 논의하였으며, 기업의 환경경영을 위한 환경성과지표, 환경심사, 전과정분석 등의 요소들을 검토하였다. 끝으로 3M, Body Shop, Baxter International 둥 3개 기업에 있어서의 환경경영의 사례를 동해 환경경영에 의한 기업이익을 엿볼 수 있었다.
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A Trend Analysis of Case Reports and Case Series on Hwa-byung in Korea
Sung, Soo-Hyun,Park, Jong-Hyun,Lee, Young-Joon,Park, Soo-Jin,Park, Eun-Jung,Han, Chang-Hyun The Society of Korean Medicine 2015 대한한의학회지 Vol.36 No.4
Objectives: This study aimed to provide a basis for treatment of Hwa-byung, a mental disorder frequently found among Koreans, by analysing published case reports and case series. Methods: In June 2015, a literature search for case reports and case series describing interventions for Hwa-byung was conducted in 7 databases for research publications in Korea, using Korean and English terms. Results: Thirty-two papers, reporting 439 cases of Hwa-byung, met the inclusion criteria. Since the first case report on Hwa-byung in 1996, case reports were continuously published until 2012. A total of 22 interventions were described, of which herbal medicine (71.9%), acupuncture (65.6%), and moxibustion (34.4%) were the most frequently described interventions. Twenty-five papers reported patterns, for which liver qi depression (28%) was most frequently used. A total of 48 outcome measures were used in 32 papers, of which Beck Depression Index (46.9%) and Symptom change (43.8%) were used in at least 10 papers. Conclusions: Since only 32 case reports/case series have been published on Hwa-byung in Korea, a strong basis for recommending standardized treatments is lacking. Therefore, a sufficient number of clinical studies, in particular randomized clinical trials (RCTs), are warranted to provide a clinical basis for treatment of Hwa-byung.
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( Sung Soo La ),( Dong Woo Kim ),( Ki Chul Shin ),( Se Young Yun ),( Suk Bae Kim ),( Jung Eun Shin ),( Hong Ja Kim ),( Il Han Song ) 대한소화기학회 2007 SIDDS Vol.9 No.-
Background/Aims: Serum alanine aminotransferase (ALT) activity, reflecting the degree of hepatic necroinflammation, is one of the most frequently measured liver tests in persons who are suspected to have liver disease. But current upper limit of normal (ULN) of ALT, 40 IU/L, often can not detect the subclinical liver disease with minimal to mild inflammation. We, therefore, evaluated the ULN of ALT of healthy adult subjects in order to assess the necessity of revision for currently accepted reference range of ALT. Methods: 23,898 adult subjects who visited for medical examination at Health Promotion Center, Dankook University Hospital, from January 2005 to December 2006, were retrospectively enrolled in the present study. We excluded the adults who had HBsAg, anti-HCV, anti-HIV, VDRL, history of current medication and alcohol consumption more than 40 g/week, and high risks for liver disease defined as BMI more than 23 kg/m2, serum cholesterol level more than 240 mg/dL, triglyceride more than 200 mg/dL, fasting glucose more than 115 mg/dL, and ultrasonographic liver diseases including fatty change. We defined updated ULN of ALT as activity below 95th percentile for each gender. Results: 5,994 adults (2,983 men, 2,961 women) met the inclusion criteria of this present study. Updated ULN of ALT levels were 38 IU/L in men and 25 IU/L in women. This ALT activity showed a tendency to increase according to age increase, and revealed positive correlation with the ultrasonographic degree of fatty liver. Serum ALT activity below 95th percentile of HBsAg or anti-HCV positive carrier subjects, whose medical conditions were equal to those of enrolled healthy subjects in aspect of biochemical and ultrasonographic finding, were 75 IU/L and 77 IU/L, respectively. Conclusions: Updated ULN of ALT was lower than currently accepted ALT activity. Considering age and gender, current reference range of serum ALT level should be revised for the detection of subclinical liver diseases such as fatty liver.
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Interaction of phospholipid with Brain Glutamate Decarboxylase
Soo Young Choi,Kyuhyung Han,Sang Ho Jang,Min Sun Song,Yong Kyu Kim,Joon Ho Choe,Sung Woo Cho 생화학분자생물학회 1994 BMB Reports Vol.27 No.3
Porcine brain glutamate decarboxylase interacts with derivatized phopholipid fluoreceine-dtpahtdtoyl-phosphatldyl ethanolamine (FL-DPPE). Upon addition of the enzyme to FL-DPPE, an increase in fluordcence intensity is discernible, together with an increase in emission anisotropy. Judging from anisotropy values, FL-DPPE is rapidly trapped by the protein matrix The binding of FL-DPPE to glutamate decacboxylese on of the dimeric enzyme into polymeric species. It appears that 2.2 moi of FL-DPPE ate bound per protein molecule, as determined by a study of fluorescence quenching. A quenching bimolecular rate constant of 1.1 × 10^9M^(-1)·S% was obtained from a Stem-Volmer plot. These results suggest that fatty add tails sense as anchoring sites for the protein dimers, whereas the fluorescent probe covalently bound to the hydrophilic head of the phospholipid, remains accessible to the collisional quencher.
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