요골동맥과 복재정맥을 이용한 관상동맥우회술의 조기성적

김관창,원태희,한재진,최수승,안재호 이화여자대학교 의과학연구소 2008 EMJ (Ewha medical journal) Vol.31 No.2

Background:Increasing interest and use of arterial conduits is based on the better patency of left internal thoracic artery(LITA) than that of saphenous vein(SV) graft. We compared the early result of coronary artery bypass grafting(CABG) using LITA and radial artery(RA group) with CABG using LITA and SV only(SV group). Material and Method:We compared the early operative results of 6 cases in RA group with 18 cases in SV group selected from 24 cases that had CABG between January 2006 and December 2006. We analyzed each group on the preoperative risk factors and operative results. Results:We can’t find significant differences in clinical and hemodynamic characteristics before surgery. There were no statically significant difference between two groups in operative mortality and each morbidities(postoperative intraaortic balloon pump insertion, bleeding, stroke, perioperative myocardial infarction, wound dehiscence), respectively. However, the overall incidence of conventional CABG using cardiopulmonary bypass was higher in RA group compared to SV group(p=0.016). Accordingly, RA group had longer duration of ventilation time(p=0.004) and ICU stay(p=0.003) than SV group with statically significant difference between two groups in hospital stay. The graft patency on postoperative coronary angiography or computerized tomographic angiography at 7-14 days after operation in both group patients were 100%(includeing LITA, RA and SV). Conclusion:We had early good operative results in RA group and SV group. 관상동맥우회술에서 내흉동맥의 장기개통률이 복재정맥보다 우수하다는 것이 알려짐과 더불어 두 개의 내흉동맥을 이용한 군에서의 장기 임상 성적이 하나의 내흉동맥만을 이용한 군에서의 성적보다 우월하다 것이 알려지면서 최근에는 동맥이식편의 사용이 증가하고 있다1)2). 좌내흉동맥이 동맥이식편중 가장 많이 그리고 오래 전부터 사용되어왔고 그 장기 개통률이 매우 우수한 것으로 증명되면서, 이식편으로 사용 가능한 다른 동맥이식편에 대한 사용이 늘어나고 있는 추세이다. 좌내흉동맥 이외에 사용될 수 있는 동맥이식편으로는 요골동맥, 우내흉동맥, 우위망막동맥 등이 있다. 이 중 우내흉동맥은 좌내흉동맥과 같이 사용한 경우 장기 생존율이 높다는 보고도 있지만 가용길이가 짧아 이용에 한계가 있고 수술시간이 길어지며 상처 합병증과 기술적인 문제 등이 있다2). 요골동맥은 Carpentier 등3)에 의해 1970년대 초 처음 이식편으로 소개되었으나 추적 관상동맥조영술상 높은 이식편 부전으로 인해 사용이 중단되었다가 1989년 다시 소개되어 주목을 받게 되었고4), 요골동맥박리술의 기술적인 변형과 항연축제의 사용으로 요골동맥의 연축을 최소화하여 사용하면서 많은 저자들에 의해 좋은 임상 성적과 높은 개통률을 보이고 있다5-7). 본 이화여자대학교 목동병원 흉부외과에서도 요골동맥을 좌내흉동맥에 이은 두 번째 동맥이식편으로 사용하고 있는데 본 연구에서는 본원에서 경험한 요골동맥을 사용하여 시행한 관상동맥우회술의 임상 성적과 수술 후 관상동맥조영술 혹은 컴퓨터 단층 혈관조영술 결과를 분석해 보고 아울러 이를 요골동맥을 사용하지 않고 내흉동맥과 복재정맥만을 이용한 군의 성적과 비교 분석해 보았다.

養液의 이온濃度 差異가 케일의 生長에 미치는 影響

지성한,이관호 호남대학교산업기술연구소 1997 산업기술연구논문집 Vol.4 No.-

신선하고 영양이 풍부한 녹즙재료로 이용되는 케일의 양액재배시 적정 이온농도 범위를 구명하기 위해 EC 0.8∼2.5 mS/cm 사이의 4수준의 양액농도에서 생장반응을 조사했다. 양액의 EC는 정식후 10일 경부터 저하하기 시작했으나 비교적 변화가 적은 반면, pH의 경우는 그 변화진폭이 매우 크게 나타났다. 양액이온농도가 높을수록 생장이 왕성했으며 특히 엽 생체중에서 표준농도는 1/4배 농도의 3.2배를 기록하였다. 총 건물중은 생체중과 유사한 결과를 보였으나 3/4배 농도와 표준농도간의 통계적 유의성은 인정되지 않았고 고농도일수록 葉 건물분배율은 증가한 반면 根 건물분배율은 낮아졌다. T/R 율은 1/4배 농도에서 가장 작았고 SLA는 반대로 저농도일수록 크게 나타났다. 이상의 결과로부터 케일의 담액수경재배에서 최대수량 확보를 위해서는 원시균형양액의 3/4과 1배 농도(EC 2.0∼2.5 mS/cm)범위로 관리하는 것이 적당한 것으로 판명되었다. The effect of 4 different ionic strengths of nutrient solution on growth in hydroponically grown kale was investigated. The plant growth increased with increasing ionic strength of nutrient solution. Specially in leaf fresh weight, there was a large difference between 1/4 strength and standard strength. The dry matter distribution in the leaf also increased with inoic strength of nutrient solution but not that in root. The 1.4 strength of nutrient solution was resulted in lowest T/R ratio and heighest SLA. In conclusion the 3.4 stregth and standard nutrient solution(EC 2.0∼2.5 mS/cm) are thought to be suitable for high yield of leaf in hydroponically grown kale plant.

3차원 전산화단층촬영 영상을 이용한 안면 연조직 두께 계측의 임상적 유용성

정호걸,김기덕,한승호,허경석,이제범,박혁,최성호,김종관,박창서 대한구강악안면방사선학회 2006 Imaging Science in Dentistry Vol.36 No.2

Purpose : To evaluate clinical usefulness of facial soft tissue thickness measurement using 3D computed tomographic images. Materials and Methods : One cadaver that had sound facial soft tissues was chosen for the study. The cadaver was scanned with a Helical CT under following scanning protocols about slice thickness and table speed; 3 mm and 3 mm/sec, 5 mm and 5 mm/sec, 7 mm and 7 mm/sec. The acquired data were reconstructed 1.5, 2.5, 3.5 mm reconstruction interval respectively and the images were transferred to a personal computer. Using a program developed to measure facial soft tissue thickness in 3D image, the facial soft tissue thickness was measured. After the ten-time repeation of the measurement for ten times, repeated measure analysis of variance (ANOVA) was adopted to compare and analyze the measurements using the three scanning protocols. Comparison according to the areas was analyzed by Mann-Whitney test. Results : There were no statistically significant intraobserver differences in the measurements of the facial soft tissue thickness using the three scanning protocols (p>0.05). There were no statistically significant differences between measurements in the 3 mm slice thickness and those in the 5 mm, 7 mm slice thickness (p>0.05). There were statistical differences in the 14 of the total 30 measured points in the 5 mm slice thickness and 22 in the 7mm slice thickness. Conclusion : The facial soft tissue thickness measurement using 3D images of 7 mm slice thickness is acceptable clinically, but those of 5 mm slice thickness is recommended for the more accurate measurement.

병렬 VOD 서버의 확장을 위한 스트라이핑 정책

최숙영,최현호,한주희,유관종 한국정보전략학회 1999 추계공동학술대회 논문집 Vol.- No.01

본 논문에서는 확장 가능한 병렬 VOD서버 모델을 제시하고, 이 별렬 VOD 서버에서 기존의 디스크 공간이 부족하여 새로운 병렬 서버를 추가할 경우, 데이터 분배 문제를 고려한다. 새로운 서버에 미디어 파일을 추가할 경우, 특정 서버에 부하가 몰리는 것을 방지하기 위해 기존의 서버에 저장되어 있는 일부 데이터들을 이동 시켜서 각 서버의 사용가능한 디스크 공간을 조정한 뒤, 각 디스크 부하를 최소화 하도록 고려하여 데이터를 저장하는 스트라이핑 방법을 제시한다.

금속사출성형에 의한 중합금 소결체 부품 제조에 관한 연구

여환균,김병진,김길수,김성훈,송준호,한관희 嶺南大學校 工業技術硏究所 2003 工業技術硏究所論文集 Vol.31 No.2

In this study we demonstrate that a small complex part of a tungsten-based heavy alloy (W-Ni-Cu) can be readily manufactured by utilizing the metal injection molding (MIM) technology. We use a simple thermoplastic binder system, containing low density polyethylene, paraffin wax, and stearic acid. To remove the organic binder from the molded part, we employ the solvent extraction and thermal debinding processes. Densification of debound parts is achieved by sintering in hydrogen atmosphere. The experimental results of the optimization of process variables to manufacture the heavy alloy part are described, with a brief discussion.

The Obturator Guiding Technique in Percutaneous Endoscopic Lumbar Discectomy

Han, In-Ho,Choi, Byung-Kwan,Cho, Won-Ho,Nam, Kyoung-Hyup The Korean Neurosurgical Society 2012 Journal of Korean neurosurgical society Vol.51 No.3

In conventional percutaneous disc surgery, introducing instruments into disc space starts by inserting a guide needle into the triangular working zone. However, landing the guide needle tip on the annular window is a challenging step in endoscopic discectomy. Surgeons tend to repeat the needling procedure to reach an optimal position on the annular target. Obturator guiding technique is a modification of standard endoscopic lumbar discectomy, in which, obturator is used to access triangular working zone instead of a guide needle. Obturator guiding technique provides more vivid feedback and easy manipulation. This technique decreases the steps of inserting instruments and takes safer route from the peritoneum.

Randomized phase 2 study of subcutaneous amifostine versus epoetin-α given 3 times weekly during concurrent chemotherapy and hyperfractionated radiotherapy for limited-disease small cell lung cancer

Han, Hye-Suk,Han, Ji-Youn,Yu, Sun Young,Pyo, Hong Ryull,Kim, Hyae Young,Cho, Kwan Ho,Lee, Dae Ho,Kim, Heung Tae,Lee, Jin Soo Wiley Subscription Services, Inc., A Wiley Company 2008 Cancer Vol.113 No.7

<B>BACKGROUND.</B><P>The purpose of the current study was to investigate the role of amifostine and epoetin-α in reducing severe toxicities during concurrent chemo-hyperfractionated radiotherapy (CCRT) for limited disease small cell lung cancer (LD-SCLC).</P><B>METHODS.</B><P>Seventy-six patients with LD-SCLC were enrolled. The treatment schedule was consisted of two 28-day cycles of cisplatin at a dose of 30 mg/m<SUP>2</SUP> (Days 1 and 8) and irinotecan at a dose of 60 mg/m<SUP>2</SUP> (Days 1, 8, and 15) followed by two 21-day cycles of cisplatin at a dose of 60 mg/m<SUP>2</SUP> (Day 1) and etoposide at a dose of 100 mg/m<SUP>2</SUP> (Days 1-3) with concurrent twice-daily thoracic radiotherapy for a total of 45 grays. Patients were randomly assigned at registration to either amifostine at a dose of 500 mg or epoetin-α at a dose of 10,000 IU subcutaneously 3 times weekly (n = 36 patients and 40 patients, respectively). Fifteen of 36 patients assigned to the amifostine arm did not receive amifostine because of a lack of supply.</P><B>RESULTS.</B><P>Amifostine treatment was associated with higher febrile neutropenia (P = .003) and grade 2 or 3 nausea (according to the National Cancer Institute Common Toxicity Criteria [version 3.0]) (P = .03). It also demonstrated a trend toward higher grade 4 leukopenia (P = .05). Grade 3 esophagitis was reported in 30% of patients treated with amifostine and 9% of patients treated with epoetin-α (P = .059). Epoetin-α treatment was associated with less grade 2 or 3 anemia (P = .031) and lower decreases in hemoglobin level during CCRT (P = .016). The median survival times for both treatment arms were comparable (22.6 months in the amifostine arm vs 25.6 months in the epoetin-α arm; P = .447).</P><B>CONCLUSIONS.</B><P>Although amifostine administered 3 times weekly during CCRT did not significantly reduce severe toxicities, epoetin-α was effective in preventing severe anemia during CCRT in patients with LD-SCLC. Other radioprotective strategies to minimize severe toxicities should be investigated Cancer 2008. © 2008 American Cancer Society.</P>

Effect of a Fibrin-Fibronectin Sealing System as a Carrier for Recombinant Human Bone Morphogenetic Protein-4 on Bone Formation in Rat Calvarial Defects

Han, Dong-Kwan,Kim, Chang-Sung,Jung, Ui-Won,Chai, Jung-Kiu,Choi, Seong-Ho,Kim, Chong-Kwan,Cho, Kyoo-Sung Wiley (John WileySons) 2005 Journal of periodontology Vol.76 No.12

Revealing the factors determining the selectivity of guaiacol HDO reaction pathways using ZrP-supported Co and Ni catalysts

Han, Geun-Ho,Lee, Min Woo,Park, Soohyung,Kim, Ho Joong,Ahn, Jae-Pyoung,Seo, Myung-gi,Lee, Kwan-Young Elsevier 2019 Journal of catalysis Vol.377 No.-

<P><B>Abstract</B></P> <P>Guaiacol, a primary chemical derived from lignin, is still an attractive candidate as a cyclical carbon source in the petroleum industry. This work newly introduced Co/ZrP and Ni/ZrP catalysts and examined their activity for guaiacol hydrodeoxygenation (HDO) in a batch reactor at 573 K and under 70 bar of H<SUB>2</SUB>. Their catalytic, surface and textural properties were investigated by XRD, N<SUB>2</SUB> adsorption-desorption, H<SUB>2</SUB>-TPR, H<SUB>2</SUB>-TPD, NH<SUB>3</SUB>-TPD, HAADF-STEM and H<SUB>2</SUB>-chemisorption. In addition, the overall reaction pathways of guaiacol to cyclohexane on Co/ZrP and Ni/ZrP were proposed. Guaiacol was converted to cyclohexane through two different pathways via two major intermediates: phenol (demethoxylation, PHE route) and 2-methoxycyclohexanol (hydrogenation, 2-M route). Co/ZrP preferred the PHE-route, while Ni/ZrP dominantly favored the 2-M-route, which resulted in a high cyclohexane yield when using Co/ZrP (76%). In this study, an ‘intrinsic H<SUB>2</SUB> supply’ was determined to be the main factor for selecting the reaction pathway. Co/ZrP, with a low intrinsic H<SUB>2</SUB> supply capacity, promoted a less H<SUB>2</SUB>-consuming pathway (PHE route), and Ni/ZrP, with a high intrinsic H<SUB>2</SUB> supply, favored the more H<SUB>2</SUB>-consuming 2-M route. Likewise, lowering the H<SUB>2</SUB> pressure (from 70 to 40 bar) could promote the PHE route and increase cyclohexane production (80%). However, the opposite trend was observed when the reaction temperature was reduced from 573 K to 523 K. For both Co/ZrP and Ni/ZrP catalysts, the production of PHE significantly decreased, while the same yield of 2-M was almost maintained. Thus, the pathway preference of Co/ZrP was reversed to the 2-M-route. Guaiacol HDO pathway preference over Co/ZrP and Ni/ZrP catalysts was characterized and the reaction conditions were investigated in this study, which could provide a guideline for effective ways to produce desired chemicals from guaiacol using Co/ZrP and Ni/ZrP.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Guaiacol HDO reactions were performed with Co/ZrP and Ni/ZrP catalysts. </LI> <LI> Strong interaction between metal and ZrP was observed by characterizations. </LI> <LI> We found out that Co/ZrP and Ni/ZrP favored different conversion pathways. </LI> <LI> The pathway preference was affected by H<SUB>2</SUB> supply of the catalysts and condition. </LI> <LI> Desired products can selectively be obtained by controlling the pathway preference. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Computer-Assisted Modified Mid-Sacrectomy for En Bloc Resection of Chordoma and Preservation of Bladder Function

Han, In-Ho,Seo, Young-Jun,Cho, Won-Ho,Choi, Byung-Kwan The Korean Neurosurgical Society 2011 Journal of Korean neurosurgical society Vol.50 No.6

A 67-year-old woman presented for evaluation of severe coccygeal pain. The computed tomography scans and magnetic resonance imaging showed an asymmetric midline sacral tumor invading the right lower portion of S2. To preserve both S2 nerve roots and to obtain negative surgical margins, a modified mid-sacrectomy with an aid of a computed navigation system was performed. The sacral tumor was excised en bloc with negative tumor margins. Both S2 nerve roots were preserved and additional reconstruction was not necessary because of minimal resection of the sacroiliac joint. We report a case of a sacral chordoma which was excised en bloc with adequate surgical margins by a computer-assisted modified mid-sacrectomy. The computed navigation system may be a useful tool for tumor targeting and safe osteotomies in sacral tumor surgery via the posterior only approach.