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한신희,박정모 성인간호학회 2002 성인간호학회지 Vol.14 No.3
Purpose: The Purpose of this research was to develop the integrative exercise program for the elderly. Method: The first step was to survey the elder's health status and general health problems The second step was to design the exercise type, intensity, time and frequency. Result: 1. Elders who implement the integrative exercise program had weaker health status, lower physical performance and more depression than any other places. 2. The integrative exercise program developed the preparation stage composed of stretching and Yudongkong-Ki exercise, the central stage was composed of range of motion exercise, muscle strength exercise and aerobic exercise with favorite and popular Korean music. The finishing stage was composed of joint rounding and Yudongkong-Ki exercise. The exercise intensity was RPE(rating perceived exertion) 10-11, maximal pulse rate 40-60%, duration started from 20min to 50min and frequency is 2-3times/wk. Conclusion: The integrative exercise program developed by the researcher is tailored exercise that is more applicable to individual cases in community settings. Eventually, the program is safely applicable to the elders, and is expected to improve the elders' physical function and quality of life.
박정모,한신희 경인여자대학 2002 경인논집 Vol.- No.9
Purpose : The Purpose of this Study was to analyze the status and depression of low income elderly living at home. Method : To identify the status was used SF-36 and the depression was used GDS. The data was collected by interview with 83 adults who visited social welfare organization and community health care center and who were 65 years of age or more subsidized Dong-Gu in Inchon City. Results : 1. Health status of elderly was low with compare of other results findings. 2. Over the 50% of the elderly was depressive. 3. Over the 50% of the elderly has no problems in functional ability 'alone clothing', 'walking around the house', 'walking around the villiage', 'walking 30 minutes'. But the highest only 24.4% in 'running, lifting a something heavy', 'cleaning the house', 'go up 2 or 3 steps' has no problem in the elderly. 4. Except the subcategory of the health status 'the health change', depression correlated with all subcategories of the health status. Conclusion: The old men living in Dong-Gu, Inchon City have severely low health status and depression symptom. They need the intervention to prevent physical functional disability and emotional distress.
Mouse의 심폐이식에서 IL-2 Receptor의 역할에 관한 연구
김대원,조정희,한덕종,이인철 울산대학교 의과대학 1993 울산의대학술지 Vol.2 No.1
Improved graft survival after organ transplantation is relied upon the innumerable studies concerning the immunologic reactions following antigen exposure and the accompanying strategies against rejection response. Cellular immunity is known to act as a major role in organ transplantation. We performed heart-lung transplantation in mice in order to define cellular immune reactions. For that purpose we analysed the functional role of the immune cells by the cellular cytotoxicity and phenotypic reactions by the IL-2 receptor(R) positive immune cells in the spleen as well as in the graft. ·Mean graft survival after the allogenic heart-lung transplantation in mice(BALB/C to CBA) was 8.5±2.5 days. ·Splenocyte cytotoxicity was the highest on the postoperative day 6 and then decreased abruptly to even lower than that of control mouse. ·Immunohistochemical analysis of spleen harvested consecutively during the postoperative period showed that proportion of IL-2R positive lymphocyte was around 20% in white pulp and scarce in red pulp illustrating nonspecific pattern regardless of rejection. ·Quantitative assay of IL-2R positive splenocyte showed the peak level on the postoperative day 6. ·IL-2R analysis of transplanted heart showed that IL-2R positive lymphocyte infiltated the heart progressively from the epicardium toward the endocardium with the maximal cellular infiltrate progressively from the epicardium toward the endocardium with the maximal cellular infiltrate on the postoperative day 4. These results illustrate that cellular cytotoxicity and expression of IL-2R positive cells have the consistent finding in terms of roles and diagnostic aid graft rejection following heart-lung transplantation in mice.
Jeong, Sung Woo,Kim, Gon-Sup,Lee, Won Sup,Kim, Yun-Hi,Kang, Nam Jun,Jin, Jong Sung,Lee, Gye Min,Kim, Soo Taek,Abd El-Aty, A.M.,Shim, Jae-Han,Shin, Sung Chul Elsevier 2015 Journal of advanced research Vol.6 No.3
<P>The present study was conducted to characterize the polyphenolic contents of lettuce leaves grown under different night-time temperatures (4, 12, and 20 °C) and cultivation durations (5, 15, and 20 days) using high performance liquid chromatography-tandem mass spectrometry (LC/MS/MS). The assay method was validated based on specificity, linearity, accuracy, precision, and the performance limit. The total polyphenolic contents were highest (2462.6 mg/kg) after transplantation at a night temperature of 20 °C on day 20 and lowest (1132.7 mg/kg) at the same temperature on day 5. Quantification and principal component analysis showed that the relative contents of quercetin and kaempferol were markedly higher during the early stage of cultivation (day 5) than those of day 15 and 20, and that night-time temperatures of 12 and 20 °C on day 20 were favorable for producing polyphenol-rich lettuce containing caffeic acid. In conclusion, a synergistic effect between high night-time temperatures (12 and 20 °C) and cultivation duration (20 days) produced lettuce rich in polyphenols compared to that at low temperature (4 °C).</P>
Effect of P-Glycoprotein and DNA Contents in Acute Leukemic Cells on Morphological Remission Rate
Kwon, Hi Jeong,Han, Kyung Ja,Lee, Kyo Young,Kang, Chang Suk,Kim, Won Il,Shim, Sang In CATHOLIC MEDICAL CENTER 1992 Bulletin of the Clinical Research Institute Vol.20 No.1
The effect on prognosis of overexpression of P-glycoprotein and cellular DNA contents in leukemic blasts are still controversial. Using flow cytometry we investigated P-glycoprotein and DNA content in leukemic blasts and the effect on the morphological remission rate of acute leukemia. The results were as follows; 1. Twelve out of all 58 cases (20.7%) revealed P-g1ycoprotein expression. Morphological remission rate was lower in cases with P-glycoprotein expression (2/12; 16.7%) than in cases without P-glycoprotein expression (24/45; 53.3%). 2. DNA content was analyzed in the same cases, and 7 cases (12.1%) revealed aneuploidy. The cases with aneuploidy (0/6; 0%) showed lower morphological remission rate than cases with diploidy (26/51; 51.0%). 3. P-glycoprotein expression was not related to BNA ploidy pattern, and was not related to S-phase fraction. From the above results, we consider P-glycoprotein expression and cellular DNA content as separate prognostic factors and recommend analysis of P-glycoprotein expression and DNA content previous to leukemia chemotherapy.
소아 Helicobacter pylori 위염의 내시경 및 병리소견 분석
김한성,서정기,이희수,장자준 대한소화기학회 2000 대한소화기학회지 Vol.36 No.1
Background/Aims : The aim of this study was to investigate characteristics of childhood Helicobacter pylori (H. pylori) gastritis. We analyzed the endoscopic features and histopathologic features. Methods : Eighty children with gastritis were enrolled in this study. Forty children were H. pylori positive and another 40 children were H. pylori negative. Their histopathologic features were classified by updated Sydney system and the endoscopic findings were analyzed. These results were also compared according to age ($gt;10 or ≤10 years). Results : Density of H. pylori was positively correlated with degree of mononuclear cell infiltration (P=0.039). In children with high density of H. pylori, the mucosal damage was significantly lower in young age group (≤10) than in old age group (P=0.04). Eighty percent of H. pylori positive cases showed nodular gastritis, while did 15% of H. pylori negative cases. Both lymphoid follicles and mononuclear cell infiltration were frequently observed in nodular gastritis (P$lt;0.001)Conclusions : Children with H. pylori infection showed the histopathologic features such as mononuclear cell infiltration, lymphoid follicles, mucosal damage and the endoscopic findings such as nodular gastritis. These features are not different according to age except for the case of severe H. pylori infection. Degree of lymphoid follicles and heavy mononuclear cell infiltration may increase in case of nodular gastritis.